Postdoctoral Research Fellow, Yuan Lab

MGH-Harvard

Boston, MA

Posted 8/15/2025

The laboratory of Dr. Shiaulou Yuan at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) is seeking highly motivated candidates for a full-time postdoctoral research fellow position.

We are a multidisciplinary group of biologists, biophysicists, and microscopists who aim to understand how fluid flows and biophysical forces shape the developing heart and how these mechanisms underlie cardiac disease pathogenesis when gone awry. Specifically, we seek to illuminate how the cilium, a hair-like structure found on most cells in the human body, acts as an “antenna” to sense and translate extracellular signals into molecular processes that sculpt the early heart (Djenoune, Mahamdeh et al., Science, 2023). The penultimate goal of our research is to advance our understanding of cardiac development and diseases by combining state-of-the-art approaches from developmental biology, cell biology, genetics, biophysics, and advanced microscopy in zebrafish animal models and human stem cells.

The ideal candidate will have: (1) a strong background working with zebrafish, (2) an PhD, MD or equivalent doctoral degree in a relevant field, (3) prior training in zebrafish husbandry and colony management, embryo micro-injection, embryo micro-dissection, confocal or light sheet microscopy, live cell imaging, quantitative image analysis, immunofluorescence, in situ hybridization, molecular cloning, CRISPR-Cas9 gene editing, recombinant protein, and/or human stem cell culture techniques, (5) a passion for developmental biology, cell biology, cardiovascular biology, and microscopy, (6) the ability to work independently and also as part of a team, (7) excellent written and verbal communication skills, (8) a strong work ethic and superb attention to details, and (9) exceptional technical and experimental skills.

Interested candidates should send a CV, a cover letter, and contact information for three references to Dr. Shiaulou Yuan ([email protected]).

Find out more about our lab’s research: https://yuan.mgh.harvard.edu

Review of applications will begin immediately and continue until the position is filled.

Last Updated 08/15/2025