Postdoctoral Associate - Deep Sea Adaptation

University of Pittsburgh

Pittsburgh, PA

Posted 10/23/2023

The MechMorpho/Davidson Lab at the University of Pittsburgh is seeking a creative and collaborative Postdoctoral Associate to study adaptation of cells and organisms to the Deep Ocean. Life in the deep ocean (> 5000 m) can experience extremely high hydrostatic pressures that would ordinarily denature proteins critical to multicellular organisms. Despite this seemingly harsh environment, many organisms thrive and reproduce. We are taking a comparative approach to identify pressure-protective pathways in deep sea organisms and to test these adaptations within surface-dwelling organisms (Xenopus frogs, zebrafish, and Nematostella anemone). The candidate will join a collaborative research network of material scientists, theorists, biophysicists, engineers, and marine biologists whose goal is to create biomimetic materials and structures based on these adaptations. The position is funded for 2+ years by the Bio-Inspired Material Architectures for Deep Sea (BIMADS) program. Successful candidates will include those with experience in live-cell imaging, bioinformatics, and/or comparative biology.

This Postdoctoral Associate will be responsible for leading a bioinformatic survey of pressure adapted organisms and developing live cell assays to assess pressure-protective pathways on non-adapted organisms. The researcher will benefit from a strongly interdisciplinary environment within the Davidson Lab and cross-disciplinary collaborations with biophysicists and cell biologists working to bridge engineering and molecular cell biology.

Interested applicants should send an email to Lance Davidson ([email protected]) and apply to requisition number 23007522 at Pitt Talent Center by visiting https://www.join.pitt.edu. Interested individuals should submit: (1) CV, (2) statement of research interest and purpose, (3) unofficial copy of full UG and Grad transcripts, (4) email and phone number for three references. This position will remain open until filled.

Last Updated 10/23/2023