Postdoctoral Position - Astrocyte lineage formation in mouse Optic nerve head/stalk

University of California, Davis

Davis, CA

Posted 7/11/2023

The Brown lab (  ) is seeking a highly motivated postdoctoral research fellow.  Mechanisms that establish and maintain cell identity are fundamental to embryonic development and adult homeostasis. Very little is known about how multipotent ocular progenitors adopt astrocytic cell fates and differentiate into glial subtypes. We established mouse models to isolate these cells during optic nerve head/optic stalk formation; and evaluate embryonic and postnatal phenotypes upon specific deletion of the Pax2 gene. This project will use techniques for genome-wide analysis of gene expression from single or multiple cells, chromatin binding and accessibility studies, classical embryology and gene expression assays.  Full funding from an NIH grant is available, but application to fellowships is also expected.

We are seeking a dynamic and rigorous scientist with a PhD degree in Biology or a related discipline.  Previous experience with genomics, molecular biology, high-throughput library preparation (bulk or single-cell) is preferable.  The successful candidate is a critical thinker, able to work independently, possess excellent quantitative and organizational/time management skills.  

Interested candidates should send a cover letter describing your expertise, what you hope to learn from the postdoctoral experience, and ultimate career goals.  Please send this letter along with a CV and contact information for three references to Nadean Brown ([email protected]).

Davis is a bicycle friendly, progressive college town, a short commute from Sacramento, <100 miles from San Francisco, Lake Tahoe, and California coast.  The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. UC Davis is committed to maintaining an atmosphere free from all forms of discrimination, harassment, exploitation, and intimidation.

Last Updated 07/11/2023