Postdoc Position in Embryology and Cancer biology
We are looking for a postdoc who can lead at least one of the following projects. The position is intended for wet lab work, yet all projects integrate large dataset analysis, which will be supported by our computational biologists in the group. This position will be ideal for those who are interested in integrating both experimental and computational biology into one’s research.
Requirement: General knowledge and skills in cell and developmental biology or cancer biology
Human cancer biology:
(1) a germline factor DDX4’s function in human cancer cells and patient tissues: Identifying the functional mechanism of DDX4, an RNA helicase, in multiple human cancer cell types (Ref: https://www.ncbi.nlm.nih.gov/pubmed/28612512)
Preferred skills: Experience in cancer cell culture, organoid culture, and/or mouse studies.
Sea urchin embryology:
(2) Localized mRNA translation on the spindle: Identifying how Vasa, an RNA helicase, regulates translation with spatiotemporal precision during asymmetric cell division of the sea urchin embryo (Ref: https://www.ncbi.nlm.nih.gov/pubmed/35444184)
(3) Molecular evolution of polarity factors and asymmetric cell division: Discovering how molecular evolution of AGS, a polarity factor, alters the asymmetric cell division and developmental program during the course of echinoderm evolution (Ref: https://www.ncbi.nlm.nih.gov/pubmed/31439829)
(4) Metabolic regulation during embryonic development: Identifying how metabolic regulation contributes to specific cellular signaling and gene regulations during asymmetric cell division of the sea urchin embryo
Preferred skills: Experience in embryology and live imaging such as microinjection, optogenetic manipulations of a protein, and 4D-confocal imaging.
Although most programs are currently funded by the federal programs next 1-4 years, the PI will also provide extensive training in writing fellowships to help the postdoc’s career. Interested individuals should contact Mamiko Yajima ([email protected]) by enclosing your CV and cover letter. Lab website: https://sites.brown.edu/yajima-lab/
Last Updated 01/26/2023