A postdoctoral position is available in the laboratory of Hamed Jafar-Nejad, M.D., at the Department of Molecular & Human Genetics, Baylor College of Medicine (firstname.lastname@example.org). The laboratory uses cell culture, Drosophila and mouse genetics to identify and characterize genetic modifiers of human developmental disorders, in hopes of shedding light on disease pathophysiology and establishing new therapeutic targets. For details about the lab’s research interests, please visit https://www.bcm.edu/research/labs/hamed-jafar-nejad.
The lab has reported a mouse model for a developmental disorder called Alagille syndrome (ALGS; OMIM 118450), and has identified two dosage-sensitive genetic modifiers of the liver phenotypes in this model (Thakurdas et al, Hepatology, 2016 and unpublished). Building on these observations, the Postdoctoral Fellow will examine the genetic and transcriptional network involved in ALGS liver abnormalities and will examine the potential utility of these modifiers for developing therapies for ALGS. These studies are likely to provide fundamental insights into normal biliary development and biliary repair in disease contexts.
Experience in mouse genetics and mammalian cell culture is essential. The ideal candidate will be a highly motivated, recent graduate with a strong publication record. To submit an application, please use the link at the top of this page.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.