Postdoctoral Position in Genetic Regulation of Neocortex Development , Children's Hospital of Philadelphia

Posted 4/4/2019

A new position is available for a postdoctoral fellow in the Lefebvre laboratory at the Children’s Hospital of Philadelphia (CHOP).

The fellow will be encouraged to deepen his/her research expertise towards reaching principal investigator independence. S/he will study mechanisms whereby SOX5 haploinsufficiency causes Lamb-Shaffer syndrome, a neurodevelopmental disease primarily characterized by global developmental delay and intellectual disability. The focus will be on deciphering the regulation of SOX5-dependent neocorticogenesis and on developing therapeutic approaches for the disease. The fellow will use cutting-edge approaches in iPSC differentiation assays, mouse models and high-throughput sequencing assays. 

Candidates must have a recent Ph.D. degree in biological sciences, a solid publication record, expertise in such areas as genomic regulation, neuroscience, stem cell biology, and mouse models, strong verbal and written communication skills, and first-rate interpersonal and organizational skills.

CHOP offers an exceptionally interactive and front-line research environment with state-of-the-art core facilities and various career-development programs. It recognizes the power of a diverse community and encourages applications from individuals with varied experiences, perspectives, and backgrounds.

Interested candidates should send a CV, description of research interests and career goals, and contact information for three references to Dr. Veronique Lefebvre (

Last Updated 04/04/2019