The Interactive Fly

The Eye-Antenna Disc and Eye Morphogenesis
Genes involved in tissue and organ development
  • Genes expressed in eye morphogenesis
  • Genes expressed in antennal morphogenesis
  • Bolwig's Organ, the Hofbauer-Buchner Eyelet and Ocelli
  • Structure of the eye
  • Development of the eye
  • Image: Specification of the eye disc primordium and establishment of dorsal/ventral asymmetry

    Eye-antenna disc
  • Specification of the eye versus the antenna
  • 5D imaging via light sheet microscopy reveals cell dynamics during the eye-antenna disc primordium formation in Drosophila
  • Transformation of eye to antenna by misexpression of a single gene
  • Genes expressed in antennal differentiation
  • Notch-dependent epithelial fold determines boundary formation between developmental fields in the Drosophila antenna

    Eye development
  • The Drosophila Adult Ommatidium
  • Atonal and EGFR signalling orchestrate rok- and Drak-dependent adherens junction remodelling during ommatidia morphogenesis
  • Mapping gene regulatory networks in Drosophila eye development by large-scale transcriptome perturbations and motif inference
  • Stochastic spineless expression creates the retinal mosaic for colour vision
  • Binary cell fate decisions and fate transformation in the Drosophila larval eye
  • The spatiotemporal order of signaling events unveils the logic of development signaling
  • Single-base pair differences in a shared motif determine differential Rhodopsin expression
  • Polycomb group genes are required to maintain a binary fate choice in the Drosophila eye
  • Wingless mediated apoptosis: How cone cells direct the death of peripheral ommatidia in the developing Drosophila eye
  • Proteasome, but not autophagy, disruption results in severe eye and wing dysmorphia: a subunit- and regulator-dependent process in Drosophila
  • A population of G2-arrested cells are selected as sensory organ precursors for the interommatidial bristles of the Drosophila eye
  • mir-279/996 cluster represses receptor tyrosine kinase signaling to determine cell fates in the Drosophila eye
  • The phosphoinositide phosphatase Sac1 regulates cell shape and microtubule stability in the developing Drosophila eye

  • The actomyosin machinery is required for Drosophila retinal lumen formation
  • Ire1 supports normal ER differentiation in developing Drosophila photoreceptors
  • Past1 modulates Drosophila eye development

  • Contribution of photoreceptor subtypes to spectral wavelength preference in Drosophila
  • Color discrimination with broadband photoreceptors
  • Genetic dissection reveals two separate retinal substrates for polarization vision in Drosophila
  • Identifying functional connections of the inner photoreceptors in Drosophila using Tango-Trace
  • Loss of Na/K-ATPase in Drosophila photoreceptors leads to blindness and age-dependent neurodegeneration
  • Proteins involved in visual signal transduction
  • Anatomical reconstruction and functional imaging reveal an ordered array of skylight polarization detectors in Drosophila

  • progression of the morphogenetic furrow across the eye disc
    Progression of the morphogenetic furrow across the eye disc

    Genes involved in eye morphogenesis
    *** indicates a special link to eye specific information

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