Fly Labs and References


  • Darren Obbard Institute of Evolutionary Biology, The University of Edinburgh
    Lewis, S. H., Webster, C. L., Salmela, H. and Obbard, D. J. (2016). Repeated duplication of Argonaute2 is associated with strong selection and testis specialization in Drosophila. Genetics [Epub ahead of print]. PubMed ID: 27535930

    Palmer, W. H. and Obbard, D. J. (2016). Variation and evolution in the glutamine-rich repeat region of Drosophila Argonaute-2. G3 (Bethesda) 6(8):2563-72. PubMed ID: 27317784

    Webster, C. L., Waldron, F. M., Robertson, S., Crowson, D., Ferrari, G., Quintana, J. F., Brouqui, J. M., Bayne, E. H., Longdon, B., Buck, A. H., Lazzaro, B. P., Akorli, J., Haddrill, P. R. and Obbard, D. J. (2015). The Discovery, Distribution, and Evolution of Viruses Associated with Drosophila melanogaster. PLoS Biol 13: e1002210. PubMed ID: 26172158

    van Mierlo, J. T., Overheul, G. J., Obadia, B., van Cleef, K. W., Webster, C. L., Saleh, M. C., Obbard, D. J. and van Rij, R. P. (2014). Novel Drosophila viruses encode host-specific suppressors of RNAi. PLoS Pathog 10: e1004256. PubMed ID: 25032815

    Obbard, D. J., Maclennan, J., Kim, K. W., Rambaut, A., O'Grady, P. M. and Jiggins, F. M. (2012). Estimating divergence dates and substitution rates in the Drosophila phylogeny. Mol Biol Evol 29: 3459-3473. PubMed ID: 22683811

  • Lucy O'Brien Molecular and Cellular Physiology, Stanford
    Ngo, S., Liang, J., Su, Y. H. and O'Brien, L. E. (2020). Disruption of EGF Feedback by Intestinal Tumors and Neighboring Cells in Drosophila. Curr Biol 30(8): 1537-1546 e1533. PubMed ID: 32243854

    Koyama, L. A. J., Aranda-Diaz, A., Su, Y. H., Balachandra, S., Martin, J. L., Ludington, W. B., Huang, K. C. and O'Brien, L. E. (2020). Bellymount enables longitudinal, intravital imaging of abdominal organs and the gut microbiota in adult Drosophila. PLoS Biol 18(1): e3000567. PubMed ID: 31986129

    Martin, J. L., Sanders, E. N., Moreno-Roman, P., Jaramillo Koyama, L. A., Balachandra, S., Du, X. and O'Brien, L. E. (2018). Long-term live imaging of the Drosophila adult midgut reveals real-time dynamics of division, differentiation and loss. Elife 7. PubMed ID: 30427308

  • Mary O'Connell Central European Institute of Technology, University Campus of Masaryk University in Brno, Czechoslovakia
    Li, X., Overton, I. M., Baines, R. A., Keegan, L. P. and O'Connell, M. A. (2013). The ADAR RNA editing enzyme controls neuronal excitability in Drosophila melanogaster. Nucleic Acids Res. PubMed ID: 24137011

    Barraud, P., Heale, B. S., O'Connell, M. A. and Allain, F. H. (2012). Solution structure of the N-terminal dsRBD of Drosophila ADAR and interaction studies with RNA. Biochimie 94: 1499-1509. PubMed ID: 22210494

    Paro, S., Li, X., O'Connell, M. A. and Keegan, L. P. (2012). Regulation and functions of ADAR in drosophila. Curr Top Microbiol Immunol 353: 221-236. PubMed ID: 21761288

    Keegan, L. P., McGurk, L., Palavicini, J. P., Brindle, J., Paro, S., Li, X., Rosenthal, J. J. and O'Connell, M. A. (2011). Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: loss of ADAR1 in insects. Nucleic Acids Res 39: 7249-7262. PubMed ID: 21622951

  • Michael O'Connor Department of Genetics, Cell Biology and Development, University of Minnesota
    Herrera, S. C., Sainz de la Maza, D., Grmai, L., Margolis, S., Plessel, R., Burel, M., O'Connor, M., Amoyel, M. and Bach, E. A. (2021). Proliferative stem cells maintain quiescence of their niche by secreting the Activin inhibitor Follistatin. Dev Cell 56(16): 2284-2294.e2286. PubMed ID: 34363758

    Pan, X. and O'Connor, M. B. (2021). Coordination among multiple receptor tyrosine kinase signals controls Drosophila developmental timing and body size. Cell Rep 36(9): 109644. PubMed ID: 34469735

    Hughson, B. N., Shimell, M. and O'Connor, M. B. (2021). AKH Signaling in D. melanogaster Alters Larval Development in a Nutrient-Dependent Manner That Influences Adult Metabolism. Front Physiol 12: 619219. PubMed ID: 33708137

    Kim, M. J. and O'Connor, M. B. (2021). Drosophila Activin signaling promotes muscle growth through InR/TORC1-dependent and -independent processes. Development 148(1). PubMed ID: 33234715

    Maselko, M., Feltman, N., Upadhyay, A., Hayward, A., Das, S., Myslicki, N., Peterson, A. J., O'Connor, M. B. and Smanski, M. J. (2020). Engineering multiple species-like genetic incompatibilities in insects. Nat Commun 11(1): 4468. PubMed ID: 32901021

    Upadhyay, A., Peterson, A. J., Kim, M. J. and O'Connor, M. B. (2020). Muscle-derived Myoglianin regulates Drosophila imaginal disc growth. Elife 9. PubMed ID: 32633716

    Khan, A., Paro, S., McGurk, L., Sambrani, N., Hogg, M. C., Brindle, J., Pennetta, G., Keegan, L. P. and O'Connell, M. A. (2020). Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy. BMC Biol 18(1): 15. PubMed ID: 32059717

    Moss-Taylor, L., Upadhyay, A., Pan, X., Kim, M. J. and O'Connor, M. B. (2019). Body size and tissue-scaling is regulated by motoneuron-derived activinbeta in Drosophila melanogaster. Genetics. PubMed ID: 31585954

    Langerak, S., Kim, M. J., Lamberg, H., Godinez, M., Main, M., Winslow, L., O'Connor, M. B. and Zhu, C. C. (2018). The Drosophila TGF-beta/Activin-like ligands Dawdle and Myoglianin appear to modulate adult lifespan through regulation of 26S proteasome function in adult muscle. Biol Open 7(4). PubMed ID: 29615416

    Kanai, M. I., Kim, M. J., Akiyama, T., Takemura, M., Wharton, K., O'Connor, M. B. and Nakato, H. (2018). Regulation of neuroblast proliferation by surface glia in the Drosophila larval brain. Sci Rep 8(1): 3730. PubMed ID: 29487331

    Makhijani, K., Alexander, B., Rao, D., Petraki, S., Herboso, L., Kukar, K., Batool, I., Wachner, S., Gold, K. S., Wong, C., O'Connor, M. B. and Bruckner, K. (2017). Regulation of Drosophila hematopoietic sites by Activin-beta from active sensory neurons. Nat Commun 8: 15990. PubMed ID: 28748922

    Kaieda, Y., Masuda, R., Nishida, R., Shimell, M., O'Connor, M. B. and Ono, H. (2017). Glue protein production can be triggered by steroid hormone signaling independent of the developmental program in Drosophila melanogaster. Dev Biol. PubMed ID: 28782527

    Song, W., Cheng, D., Hong, S., Sappe, B., Hu, Y., Wei, N., Zhu, C., O'Connor, M. B., Pissios, P. and Perrimon, N. (2017). Midgut-derived Activin regulates glucagon-like action in the fat body and glycemic control. Cell Metab 25(2): 386-399. PubMed ID: 28178568

    Schiesari, L., Andreatta, G., Kyriacou, C. P., O'Connor, M. B. and Costa, R. (2016). The Insulin-Like Proteins dILPs-2/5 Determine Diapause Inducibility in Drosophila. PLoS One 11: e0163680. PubMed ID: 27689881

  • Kate O'Connor-Giles Laboratory of Cell & Molecular Biology, University of Wisconsin, Madison
    Hoover, K. M., Gratz, S. J., Qi, N., Herrmann, K. A., Liu, Y., Perry-Richardson, J. J., Vanderzalm, P. J., O'Connor-Giles, K. M. and Broihier, H. T. (2019). The calcium channel subunit alpha2delta-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway. Nat Commun 10(1): 5575. PubMed ID: 31811118

    Gratz, S. J., Goel, P., Bruckner, J. J., Hernandez, R. X., Khateeb, K., Macleod, G. T., Dickman, D. and O'Connor-Giles, K. M. (2019). Endogenous tagging reveals differential regulation of Ca(2+) channels at single AZs during presynaptic homeostatic potentiation and depression. J Neurosci. PubMed ID: 30692227

    Bruckner, J. J., Zhan, H., Gratz, S. J., Rao, M., Ukken, F., Zilberg, G. and O'Connor-Giles, K. M. (2017). Fife organizes synaptic vesicles and calcium channels for high-probability neurotransmitter release. J Cell Biol 216(1): 231-246. PubMed ID: 27998991

    Zhan, H., Bruckner, J., Zhang, Z. and O'Connor-Giles, K. (2016). Three-dimensional imaging of Drosophila motor synapses reveals ultrastructural organizational patterns. J Neurogenet 30(3-4): 237-246. PubMed ID: 27981875

    Ukken, F. P., Bruckner, J. J., Weir, K. L., Hope, S. J., Sison, S. L., Birschbach, R. M., Hicks, L., Taylor, K. L., Dent, E. W., Gonsalvez, G. B. and O'Connor-Giles, K. M. (2015). BAR-SH3 Sorting nexins are conserved Nervous wreck interactors that organize synapses and promote neurotransmission. J Cell Sci. PubMed ID: 26567222

    Gratz, S. J., Rubinstein, C. D., Harrison, M. M., Wildonger, J. and O'Connor-Giles, K. M. (2015). CRISPR-Cas9 Genome Editing in Drosophila. Curr Protoc Mol Biol 111: 31 32 31-31 32 20. PubMed ID: 26131852

    Gratz, S. J., Harrison, M. M., Wildonger, J. and O'Connor-Giles, K. M. (2015). Precise Genome Editing of Drosophila with CRISPR RNA-Guided Cas9. Methods Mol Biol 1311: 335-348. PubMed ID: 25981484

    Gratz, S. J., Ukken, F. P., Rubinstein, C. D., Thiede, G., Donohue, L. K., Cummings, A. M. and O'Connor-Giles, K. M. (2014). Highly specific and efficient CRISPR/Cas9-catalyzed homology-directed repair in Drosophila. Genetics 196: 961-971. PubMed ID: 24478335

    Bruckner, J. J., Gratz, S. J., Slind, J. K., Geske, R. R., Cummings, A. M., Galindo, S. E., Donohue, L. K. and O'Connor-Giles, K. M. (2012). Fife, a Drosophila Piccolo-RIM homolog, promotes active zone organization and neurotransmitter release. J Neurosci 32: 17048-17058. PubMed ID: 23197698

  • Michael O'Connor Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis
    Pan, X., Neufeld, T. P. and O'Connor, M. B. (2019). A tissue- and temporal-specific autophagic switch controls Drosophila pre-metamorphic nutritional checkpoints. Curr Biol 29(17): 2840-2851.e2844. PubMed ID: 31422886

    Setiawan, L., Pan, X., Woods, A. L., O'Connor, M. B. and Hariharan, I. K. (2018). The BMP2/4 ortholog Dpp can function as an inter-organ signal that regulates developmental timing. Life Sci Alliance 1(6): e201800216. PubMed ID: 30515478

    Shimell, M., Pan, X., Martin, F. A., Ghosh, A. C., Leopold, P., O'Connor, M. B. and Romero, N. M. (2018). Prothoracicotropic hormone modulates environmental adaptive plasticity through the control of developmental timing. Development 145(6). PubMed ID: 29467242

    Kim, M. J. and O'Connor, M. B. (2014). Anterograde Activin Signaling Regulates Postsynaptic Membrane Potential and GluRIIA/B Abundance at the Drosophila Neuromuscular Junction. PLoS One 9: e107443. PubMed ID: 25255438

    Ting, C. Y., McQueen, P. G., Pandya, N., Lin, T. Y., Yang, M., Reddy, O. V., O'Connor, M. B., McAuliffe, M. and Lee, C. H. (2014). Photoreceptor-Derived Activin Promotes Dendritic Termination and Restricts the Receptive Fields of First-Order Interneurons in Drosophila. Neuron. PubMed ID: 24462039

    Yamanaka, N., Romero, N. M., Martin, F. A., Rewitz, K. F., Sun, M., O'Connor, M. B. and Leopold, P. (2013). Neuroendocrine control of Drosophila larval light preference. Science 341: 1113-1116. PubMed ID: 24009394

    Peterson, A. J. and O'Connor, M. B. (2013). Activin receptor inhibition by Smad2 regulates Drosophila wing disc patterning through BMP-response elements. Development 140: 649-659. PubMed ID: 23293296

    Yamanaka, N., Rewitz, K. F. and O'Connor, M. B. (2013). Ecdysone control of developmental transitions: lessons from Drosophila research. Annu Rev Entomol 58: 497-516. PubMed ID: 23072462

    Peterson, A. J., Jensen, P. A., Shimell, M., Stefancsik, R., Wijayatonge, R., Herder, R., Raftery, L. A. and O'Connor, M. B. (2012). R-Smad competition controls activin receptor output in Drosophila. PLoS One 7: e36548. PubMed ID: 22563507

    Dimitroff, B., Howe, K., Watson, A., Campion, B., Lee, H. G., Zhao, N., O'Connor, M. B., Neufeld, T. P. and Selleck, S. B. (2012). Diet and energy-sensing inputs affect TorC1-mediated axon misrouting but not TorC2-directed synapse growth in a Drosophila model of tuberous sclerosis. PLoS One 7: e30722. PubMed ID: 22319582

  • Ward Odenwald Neural Cell-Fate Determinants Section, NINDS, NIH, Bethesda
    Brody, T., Yavatkar, A., Kuzin, A. and Odenwald, W. F. (2020). Ultraconserved Non-coding DNA Within Diptera and Hymenoptera. G3 (Bethesda). PubMed ID: 32601058

    Luan, H., Kuzin, A., Odenwald, W. F. and White, B. H. (2020). Cre-assisted fine-mapping of neural circuits using orthogonal split inteins. Elife 9. PubMed ID: 32286225

    Ross, J., Kuzin, A., Brody, T. and Odenwald, W. F. (2018). Mutational analysis of a Drosophila neuroblast enhancer governing nubbin expression during CNS development. Genesis. PubMed ID: 30005136

    Kuzin, A., Smith, S., Brody, T. and Odenwald, W. F. (2018). Structure and cis-regulatory analysis of a Drosophila grainyhead neuroblast enhancer. Genesis 56(3): e23094. PubMed ID: 29417712

    Brody, T., Yavatkar, A. S., Park, D. S., Kuzin, A., Ross, J. and Odenwald, W. F. (2017). Flavivirus and Filovirus EvoPrinters: New alignment tools for the comparative analysis of viral evolution. PLoS Negl Trop Dis 11(6): e0005673. PubMed ID: 28622346

    Ross, J., Kuzin, A., Brody, T. and Odenwald, W. F. (2015). cis-regulatory analysis of the Drosophila pdm locus reveals a diversity of neural enhancers. BMC Genomics 16: 700. PubMed ID: 26377945

    Awasaki, T., Kao, C. F., Lee, Y. J., Yang, C. P., Huang, Y., Pfeiffer, B. D., Luan, H., Jing, X., Huang, Y. F., He, Y., Schroeder, M. D., Kuzin, A., Brody, T., Zugates, C. T., Odenwald, W. F. and Lee, T. (2014). Making Drosophila lineage-restricted drivers via patterned recombination in neuroblasts. Nat Neurosci. PubMed ID: 24561995

    Wang, Y. C., Yang, J. S., Johnston, R., Ren, Q., Lee, Y. J., Luan, H., Brody, T., Odenwald, W. F. and Lee, T. (2014). Drosophila intermediate neural progenitors produce lineage-dependent related series of diverse neurons. Development 141: 488. PubMed ID: 24381200

    Kundu, M., Kuzin, A., Lin, T. Y., Lee, C. H., Brody, T., Odenwald, W. F. (2013) cis-Regulatory Complexity within a Large Non-Coding Region in the Drosophila Genome. PLoS One 8: e60137. PubMed ID: 23613719

    Kuzin, A., Kundu, M., Ross, J., Koizumi, K., Brody, T. and Odenwald, W. F. (2012). The cis-regulatory dynamics of the Drosophila CNS determinant castor are controlled by multiple sub-pattern enhancers. Gene Expr Patterns 12: 261-272. PubMed ID: 22691242

    Brody, T., Yavatkar, A.S., Kuzin, A., Kundu, M., Tyson, L.J., Ross, J., Lin, T.Y., Lee, C.H., Awasaki, T., Lee, T. and Odenwald, W.F. (2012) Use of a Drosophila genome-wide conserved sequence database to identify functionally related cis-regulatory enhancers, Developmental Dynamics 241, 169-189. PubMed ID: 22174086

  • Janis O'Donnell Biological Sciences, University of Alabama
    Maitra, U., Scaglione, M. N., Chtarbanova, S. and O'Donnell, J. M. (2019). Innate immune responses to paraquat exposure in a Drosophila model of Parkinson's disease. Sci Rep 9(1): 12714. PubMed ID: 31481676

    D'Silva, N. M., Donini, A. and O'Donnell, M. J. (2017). The roles of V-type H+-ATPase and Na+/K+-ATPase in energizing K+ and H+ transport in larval Drosophila gut epithelia. J Insect Physiol. PubMed ID: 28188726

    Bednářová, A., Hanna, M.E., Rakshit, K., O'Donnell, J.M. and Krishnan, N. (2017). Disruption of dopamine homeostasis has sexually dimorphic effects on senescence characteristics of Drosophila melanogaster. Eur J Neurosci [Epub ahead of print]. PubMed ID: 28112452

    Browne, A. and O'Donnell, M. J. (2016). Segment-specific Ca transport by isolated Malpighian tubules of Drosophila melanogaster: A comparison of larval and adult stages. J Insect Physiol 87: 1-11. PubMed ID: 26802560

    Ajjuri, R. R. and O'Donnell, J. M. (2013). Novel Whole-tissue Quantitative Assay of Nitric Oxide Levels in Drosophila Neuroinflammatory Response. J Vis Exp. PubMed ID: 24335747

    Browne, A. and O'Donnell, M. J. (2013). Ammonium secretion by Malpighian tubules of Drosophila melanogaster: application of a novel ammonium-selective microelectrode. J Exp Biol. PubMed ID: 23821719

    Seabrooke, S. and O'Donnell, M. J. (2013). Oatp58Dc contributes to blood-brain barrier function by excluding organic anions from the Drosophila brain. Am J Physiol Cell Physiol. PubMed ID: 23804204

    Chahine, S., Seabrooke, S. and O'Donnell, M. J. (2012). Effects of genetic knock-down of organic anion transporter genes on secretion of fluorescent organic ions by Malpighian tubules of Drosophila melanogaster. Arch Insect Biochem Physiol 81: 228-240. PubMed ID: 22972675

    Chahine, S., Campos, A. and O'Donnell, M. J. (2012). Genetic knockdown of a single organic anion transporter alters the expression of functionally related genes in Malpighian tubules of Drosophila melanogaster. J Exp Biol 215: 2601-2610. PubMed ID: 22786636

    Ruiz-Sanchez, E. and O'Donnell, M. J. (2012). Effects of the microbial metabolite destruxin A on ion transport by the gut and renal epithelia of Drosophila melanogaster. Arch Insect Biochem Physiol 80: 109-122. PubMed ID: 22522660

  • Michael O'Donnell Department of Biology, McMasters University, Hamilton, Ontario
    Vanderveken, M. and O'Donnell, M. J. (2014). Effects of Diuretic hormone 31, Drosokinin, and Allatostatin a on transepithelial k transport and contraction frequency in the midgut and hindgut of larval Drosophila melanogaster. Arch Insect Biochem Physiol. PubMed ID: 24408875

    Browne, A. and O'Donnell, M. J. (2013). Ammonium secretion by Malpighian tubules of Drosophila melanogaster: application of a novel ammonium-selective microelectrode. J Exp Biol 216: 3818-3827. PubMed ID: 23821719

    Seabrooke, S. and O'Donnell, M. J. (2013). Oatp58Dc contributes to blood-brain barrier function by excluding organic anions from the Drosophila brain. Am J Physiol Cell Physiol 305: C558-567. PubMed ID: 23804204

    Chahine, S., Seabrooke, S. and O'Donnell, M. J. (2012). Effects of genetic knock-down of organic anion transporter genes on secretion of fluorescent organic ions by Malpighian tubules of Drosophila melanogaster. Arch Insect Biochem Physiol 81: 228-240. PubMed ID: 22972675

  • Diane O'Dowd Developmental & Cell Biology, University of California, Irvine
    Roemmich, A. J., Vu, T., Lukacsovich, T., Hawkins, C., Schutte, S. S. and O'Dowd, D. K. (2021). Seizure phenotype and underlying cellular defects in Drosophila knock-in models of DS (R1648C) and GEFS+ (R1648H) SCN1A epilepsy. eNeuro. PubMed ID: 34475263

    Guven-Ozkan, T., Busto, G. U., Schutte, S. S., Cervantes-Sandoval, I., O'Dowd, D. K. and Davis, R. L. (2016). MiR-980 is a memory suppressor microRNA that regulates the autism-susceptibility gene A2bp1. Cell Rep 14: 1698-1709. PubMed ID: 26876166

    Schutte, R. J., Schutte, S. S., Algara, J., Barragan, E. V., Gilligan, J., Staber, C., Savva, Y. A., Smith, M. A., Reenan, R. and O'Dowd, D. K. (2014). Knock-in model of Dravet Syndrome reveals a constitutive and conditional reduction in sodium current. J Neurophysiol. PubMed ID: 24805083

    Janakaloti Narayanareddy, B. R., Vartiainen, S., Hariri, N., O'Dowd, D. K. and Gross, S. P. (2014). A biophysical analysis of mitochondrial movement: differences between transport in neuronal cell bodies versus processes. Traffic. PubMed ID: 24673933

    Iniguez, J., Schutte, S. S. and O'Dowd, D. K. (2013). Cav3-type alpha1T calcium channels mediate transient calcium currents that regulate repetitive firing in Drosophila antennal lobe PNs. J Neurophysiol. PubMed ID: 23864373

    Gu, H., Jiang, S. A., Campusano, J. M., Iniguez, J., Su, H., Hoang, A. A., Lavian, M., Sun, X. and O'Dowd, D. K. (2009). Cav2-type calcium channels encoded by cac regulate AP-independent neurotransmitter release at cholinergic synapses in adult Drosophila brain. J Neurophysiol 101: 42-53. PubMed ID: 19004991

  • Pat O'Farrell Department of Biochemistry and Biophysics, UCSF
    Strong, I. J. T., Lei, X., Chen, F., Yuan, K. and O'Farrell, P. H. (2020). Interphase-arrested Drosophila embryos activate zygotic gene expression and initiate mid-blastula transition events at a low nuclear-cytoplasmic ratio. PLoS Biol 18(10): e3000891. PubMed ID: 33090988

    Chiang, A. C., McCartney, E., O'Farrell, P. H. and Ma, H. (2019). A Genome-wide Screen Reveals that Reducing Mitochondrial DNA Polymerase Can Promote Elimination of Deleterious Mitochondrial Mutations. Curr Biol 29(24): 4330-4336. PubMed ID: 31786061

    Seller, C. A., Cho, C. Y. and O'Farrell, P. H. (2019). Rapid embryonic cell cycles defer the establishment of heterochromatin by Eggless/SetDB1 in Drosophila. Genes Dev. PubMed ID: 30808658

    Seller, C. A. and O'Farrell, P. H. (2018). Rif1 prolongs the embryonic S phase at the Drosophila mid-blastula transition. PLoS Biol 16(5): e2005687. Pubmed ID: 29746464

    Ma, H. and O'Farrell, P.H. (2016). Selfish drive can trump function when animal mitochondrial genomes compete. Nat Genet [Epub ahead of print]. PubMed ID: 27270106

    Yuan, K. and O'Farrell, P. H. (2016). TALE-light imaging reveals maternally guided, H3K9me2/3-independent emergence of functional heterochromatin in Drosophila embryos. Genes Dev 30: 579-593. PubMed ID: 26915820

    Yuan, K., and O'Farrell, P.H. (2015). Cyclin B3 is a mitotic cyclin that promotes the metaphase-anaphase transition. Curr Biol [Epub ahead of print]. PubMed ID: 25754637

    Farrell, J. A. and O'Farrell, P. H. (2014). From Egg to Gastrula: How the Cell Cycle Is Remodeled During the Drosophila Mid-Blastula Transition. Annu Rev Genet. PubMed ID: 25195504

    Yuan, K., Shermoen, A. W. and O'Farrell, P. H. (2014). Illuminating DNA replication during Drosophila development using TALE-lights. Curr Biol 24: R144-145. PubMed ID: 24556431
    Yuan, K., Farrell, J. A. and O'Farrell, P. H. (2012). Different cyclin types collaborate to reverse the S-phase checkpoint and permit prompt mitosis. J. Cell Biol. 198(6): 973-80. PubMed ID: 22965907

    DeLuca, S. Z. and O'Farrell, P. H. (2012). Barriers to male transmission of mitochondrial DNA in sperm development. Dev Cell 22: 660-668. PubMed ID: 22421049
  • Hiro Ohkura The Wellcome Trust Centre for Cell Biology, The University of Edinburgh,
    Barbosa, P., Zhaunova, L., Debilio, S., Steccanella, V., Kelly, V., Ly, T. and Ohkura, H. (2021). SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56. J Cell Biol 220(2). PubMed ID: 33382409

    Costa, M. F. A. and Ohkura, H. (2019). The molecular architecture of the meiotic spindle is remodeled during metaphase arrest in oocytes. J Cell Biol. PubMed ID: 31278080

    Rome, P. and Ohkura, H. (2018). A novel microtubule nucleation pathway for meiotic spindle assembly in oocytes. J Cell Biol. PubMed ID: 30087124

    Breuer, M. and Ohkura, H. (2015). A negative loop within the nuclear pore complex controls global chromatin organization. Genes Dev 29: 1789-1794. PubMed ID: 26341556

    Nikalayevich, E. and Ohkura, H. (2014). The NuRD nucleosome remodelling complex and NHK-1 kinase are required for chromosome condensation in oocytes. J Cell Sci. PubMed ID: 25501812

    Clohisey, S. M., Dzhindzhev, N. S. and Ohkura, H. (2014). Kank Is an EB1 Interacting Protein that Localises to Muscle-Tendon Attachment Sites in Drosophila. PLoS One 9: e106112. PubMed ID: 25203404

    Lesniewska, K., Warbrick, E. and Ohkura, H. (2014). Peptide aptamers define distinct EB1- and EB3-binding motifs and interfere with microtubule dynamics. Mol Biol Cell. PubMed ID: 24478452

    Syred, H. M., Welburn, J., Rappsilber, J. and Ohkura, H. (2013). Cell cycle regulation of microtubule interactomes: multi-layered regulation is critical for the interphase/mitosis transition. Mol Cell Proteomics. PubMed ID: 23893837

    Loh, B. J., Cullen, C. F., Vogt, N. and Ohkura, H. (2012). The conserved kinase SRPK regulates karyosome formation and spindle microtubule assembly in Drosophila oocytes. J Cell Sci 125: 4457-4462. PubMed ID: 22854045

    Meireles, A. M., Dzhindzhev, N. S. and Ohkura, H. (2011). Kebab: kinetochore and EB1 associated basic protein that dynamically changes its localisation during Drosophila mitosis. PLoS One 6: e24174. PubMed ID: 21912673

    Parton, R. M., Hamilton, R. S., Ball, G., Yang, L., Cullen, C. F., Lu, W., Ohkura, H. and Davis, I. (2011). A PAR-1-dependent orientation gradient of dynamic microtubules directs posterior cargo transport in the Drosophila oocyte. J Cell Biol 194: 121-135. PubMed ID: 21746854

  • Benjamin Ohlstein Department of Genetics and Development, Columbia University
    Lucchetta, E.M. and Ohlstein, B. (2017). Amitosis of Polyploid Cells Regenerates Functional Stem Cells in the Drosophila Intestine. Cell Stem Cell [Epub ahead of print]. PubMed ID: 28343984

    Guo, Z. and Ohlstein, B. (2015). Stem cell regulation. Bidirectional Notch signaling regulates Drosophila intestinal stem cell multipotency. Science 350 [Epub ahead of print]. PubMed ID: 26586765

    Driver, I. and Ohlstein, B. (2014). Specification of regional intestinal stem cell identity during Drosophila metamorphosis. Development. PubMed ID: 24700821

    Lucchetta, E. M. and Ohlstein, B. (2012). The Drosophila midgut: a model for stem cell driven tissue regeneration. Wiley Interdiscip Rev Dev Biol 1: 781-788. PubMed ID: 23799573

    Guo, Z., Driver, I. and Ohlstein, B. (2013). Injury-induced BMP signaling negatively regulates Drosophila midgut homeostasis. J Cell Biol. PubMed ID: 23733344

    Choi, N. H., Lucchetta, E. and Ohlstein B. (2011). Nonautonomous regulation of Drosophila midgut stem cell proliferation by the insulin-signaling pathway. Proc. Natl. Acad. Sci. 108(46): 18702-7. PubMed ID: 22049341

    Mathur, D., Bost, A., Driver, I. and Ohlstein, B. (2010). A transient niche regulates the specification of Drosophila intestinal stem cells. Science 327: 210-213. PubMed ID: 20056890

  • Katsutomo Okamura Temasek Life Sciences Laboratory Limited, Singapore
    Goh, E. and Okamura, K. (2018). Hidden sequence specificity in loading of single-stranded RNAs onto Drosophila Argonautes. Nucleic Acids Res. PubMed ID: 30590701

    Zhou, L., Lim, M. Y., Kaur, P., Saj, A., Bortolamiol-Becet, D., Gopal, V., Tolwinski, N., Tucker-Kellogg, G. and Okamura, K. (2018). Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during Drosophila development. Elife 7. PubMed ID: 30024380

    Lim, M. Y., Ng, A. W., Chou, Y., Lim, T. P., Simcox, A., Tucker-Kellogg, G. and Okamura, K. (2016). The Drosophila Dicer-1 Partner Loquacious Enhances miRNA Processing from Hairpins with Unstable Structures at the Dicing Site. Cell Rep 15: 1795-1808. PubMed ID: 27184838

    Wen, J., Duan, H., Bejarano, F., Okamura, K., Fabian, L., Brill, J. A., Bortolamiol-Becet, D., Martin, R., Ruby, J. G. and Lai, E. C. (2015). Adaptive regulation of testis gene expression and control of male fertility by the Drosophila hairpin RNA pathway. [Corrected]. Mol Cell 57: 165-178. PubMed ID: 25544562

    Wen, J., Mohammed, J., Bortolamiol-Becet, D., Tsai, H., Robine, N., Westholm, J. O., Ladewig, E., Dai, Q., Okamura, K., Flynt, A. S., Zhang, D., Andrews, J., Cherbas, L., Kaufman, T. C., Cherbas, P., Siepel, A. and Lai, E. C. (2014). Diversity of miRNAs, siRNAs, and piRNAs across 25 Drosophila cell lines. Genome Res 24: 1236-1250. PubMed ID: 24985917

    Hain, D., Bettencourt, B. R., Okamura, K., Csorba, T., Meyer, W., Jin, Z., Biggerstaff, J., Siomi, H., Hutvagner, G., Lai, E. C., Welte, M. and Muller, H. A. (2010). Natural variation of the amino-terminal glutamine-rich domain in Drosophila argonaute2 is not associated with developmental defects. PLoS One 5: e15264. PubMed ID: 21253006

  • Cahir O'Kane Department of Genetics, University of Cambridge
    Oliva, M. K., Perez-Moreno, J. J., O'Shaughnessy, J., Wardill, T. J. and O'Kane, C. J. (2020). Endoplasmic Reticulum Lumenal Indicators in Drosophila Reveal Effects of HSP-Related Mutations on Endoplasmic Reticulum Calcium Dynamics. Front Neurosci 14: 816. PubMed ID: 32903680

    Perez-Moreno, J. J. and O'Kane, C. J. (2018). GAL4 Drivers Specific for Type Ib and Type Is Motor Neurons in Drosophila. G3 (Bethesda). PubMed ID: 30530644

    Yalcin, B., Zhao, L., Stofanko, M., O'Sullivan, N. C., Kang, Z. H., Roost, A., Thomas, M. R., Zaessinger, S., Blard, O., Patto, A. L., Sohail, A., Baena, V., Terasaki, M. and O'Kane, C. J. (2017). Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins. Elife 6. PubMed ID: 28742022

    Pavel, M., Imarisio, S., Menzies, F. M., Jimenez-Sanchez, M., Siddiqi, F. H., Wu, X., Renna, M., O'Kane, C. J., Crowther, D. C. and Rubinsztein, D. C. (2016). CCT complex restricts neuropathogenic protein aggregation via autophagy. Nat Commun 7: 13821. PubMed ID: 27929117

    Menzies, F. M., Garcia-Arencibia, M., Imarisio, S., O'Sullivan, N. C., Ricketts, T., Kent, B. A., Rao, M. V., Lam, W., Green-Thompson, Z. W., Nixon, R. A., Saksida, L. M., Bussey, T. J., O'Kane, C. J. and Rubinsztein, D. C. (2014). Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity. Cell Death Differ. PubMed ID: 25257175

    Masuda-Nakagawa, L. M., Ito, K., Awasaki, T. and O'Kane, C. J. (2014). A single GABAergic neuron mediates feedback of odor-evoked signals in the mushroom body of larval Drosophila. Front Neural Circuits 8: 35. PubMed ID: 24782716

    O'Sullivan, N. C., Drager, N. and O'Kane, C. J. (2013). Characterization of the Drosophila Atlastin Interactome Reveals VCP as a Functionally Related Interactor. J Genet Genomics 40: 297-306. PubMed ID: 23790629

    O'Sullivan, N. C., Jahn, T. R., Reid, E. and O'Kane, C. J. (2012). Reticulon-like-1, the Drosophila orthologue of the hereditary spastic paraplegia gene reticulon 2, is required for organization of endoplasmic reticulum and of distal motor axons. Hum Mol Genet 21: 3356-3365. PubMed ID: 22543973

    Rocha, J. J., Korolchuk, V. I., Robinson, I. M. and O'Kane, C. J. (2011). A phagocytic route for uptake of double-stranded RNA in RNAi. PLoS One 6: e19087. PubMed ID: 21559499

  • Hitoshi Okazawa Department of Neuropathology, Tokyo Medical and Dental University.
    Shiraishi, R., Tamura, T., Sone, M. and Okazawa, H. (2014). Systematic analysis of fly models with multiple drivers reveals different effects of ataxin-1 and huntingtin in neuron subtype-specific expression. PLoS One 9: e116567. PubMed ID: 25551764

    Barclay, S. S., Tamura, T., Ito, H., Fujita, K., Tagawa, K., Shimamura, T., Katsuta, A., Shiwaku, H., Sone, M., Imoto, S., Miyano, S. and Okazawa, H. (2013). Systems biology analysis of Drosophila in vivo screen data elucidates core networks for DNA damage repair in SCA1. Hum Mol Genet. PubMed ID: 24179173

    Tamura, T., Sone, M., Nakamura, Y., Shimamura, T., Imoto, S., Miyano, S. and Okazawa, H. (2013). A restricted level of PQBP1 is needed for the best longevity of Drosophila. Neurobiol Aging 34: 356 e311-320. PubMed ID: 22901698

    Tamura, T., Sone, M., Iwatsubo, T., Tagawa, K., Wanker, E. E. and Okazawa, H. (2011). Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease. PLoS One 6: e27408. PubMed ID: 22096569

  • Ludmila Olenina Institute of Molecular Genetics, Russian Academy of Sciences
    Adashev, V. E., Kotov, A. A., Bazylev, S. S., Shatskikh, A. S., Aravin, A. A. and Olenina, L. V. (2020). Stellate Genes and the piRNA Pathway in Speciation and Reproductive Isolation of Drosophila melanogaster. Front Genet 11: 610665. PubMed ID: 33584811

    Kotov, A. A., Godneeva, B. K., Olenkina, O. M., Adashev, V. E., Trostnikov, M. V. and Olenina, L. V. (2020). The Drosophila RNA Helicase Belle (DDX3) Non-Autonomously Suppresses Germline Tumorigenesis Via Regulation of a Specific mRNA Set. Cells 9(3). PubMed ID: 32111103

    Kotov, A. A., Adashev, V. E., Godneeva, B. K., Ninova, M., Shatskikh, A. S., Bazylev, S. S., Aravin, A. A. and Olenina, L. V. (2019). piRNA silencing contributes to interspecies hybrid sterility and reproductive isolation in Drosophila melanogaster. Nucleic Acids Res. PubMed ID: 30788506

    Ryazansky, S. S., Kotov, A. A., Kibanov, M. V., Akulenko, N. V., Korbut, A. P., Lavrov, S. A., Gvozdev, V. A. and Olenina, L. V. (2016). RNA helicase Spn-E is required to maintain Aub and AGO3 protein levels for piRNA silencing in the germline of Drosophila. Eur J Cell Biol. PubMed ID: 27320195

    Kotov, A. A., Olenkina, O. M., Kibanov, M. V. and Olenina, L. V. (2016). RNA helicase Belle (DDX3) is essential for male germline stem cell maintenance and division in Drosophila. Biochim Biophys Acta [Epub ahead of print]. PubMed ID: 26876306

    Kibanov, M. V., Kotov, A. A., Olenina, L. V. (2013) Multicolor fluorescence imaging of the whole mount Drosophila testes for studying spermatogenesis. Anal Biochem. PubMed ID: 23357237

    Olenkina, O. M., Egorova, K. S., Aravin, A. A., Naumova, N. M., Gvozdev, V. A. and Olenina, L. V. (2012). Mapping of cis-regulatory sites in the promoter of testis-specific stellate genes of Drosophila melanogaster. Biochemistry (Mosc) 77: 1285-1293. PubMed ID: 23240566

    Kibanov, M. V., Gvozdev, V. A. and Olenina, L. V. (2012). Germ granules in spermatogenesis of Drosophila: Evidences of contribution to the piRNA silencing. Commun Integr Biol 5: 130-133. PubMed ID: 22808315

  • Patricio Olguín Instituto de Ciencias Biomédicas, University of Chile
    Manieu, C., Olivares, G. H., Vega-Macaya, F., Valdivia, M. and Olguin, P. (2018). Jitterbug/Filamin and Myosin-II form a complex in tendon cells required to maintain epithelial shape and polarity during musculoskeletal system development. Mech Dev. PubMed ID: 30213743

    Valdivia, M., Vega-Macaya, F. and Olguin, P. (2017). Mechanical Control of Myotendinous Junction Formation and Tendon Differentiation during Development. Front Cell Dev Biol 5: 26. PubMed ID: 28386542

    Vega-Macaya, F., Manieu, C., Valdivia, M., Mlodzik, M. and Olguin, P. (2016). Establishment of the Muscle-Tendon Junction During Thorax Morphogenesis in Drosophila Requires the Rho-Kinase. Genetics 204(3): 1139-1149. PubMed ID: 27585845

  • Brian Oliver NIDDK, National Institutes of Health
    Mahadevaraju, S., Fear, J. M., Akeju, M., Galletta, B. J., Pinheiro, M., Avelino, C. C., Cabral-de-Mello, D. C., Conlon, K., Dell'Orso, S., Demere, Z., Mansuria, K., Mendonça, C. A., Palacios-Gimenez, O. M., Ross, E., Savery, M., Yu, K., Smith, H. E., Sartorelli, V., Yang, H., Rusan, N. M., Vibranovski, M. D., Matunis, E. and Oliver, B. (2021). Dynamic sex chromosome expression in Drosophila male germ cells. Nat Commun 12(1): 892. PubMed ID: 33563972

    Galletta, B. J., Ortega, J. M., Smith, S. L., Fagerstrom, C. J., Fear, J. M., Mahadevaraju, S., Oliver, B. and Rusan, N. M. (2020). Sperm Head-Tail Linkage Requires Restriction of Pericentriolar Material to the Proximal Centriole End. Dev Cell. PubMed ID: 32169161

    Benner, L., Castro, E. A., Whitworth, C., Venken, K. J. T., Yang, H., Fang, J., Oliver, B., Cook, K. R. and Lerit, D. A. (2019). Drosophila heterochromatin stabilization requires the zinc-finger protein Small ovary. Genetics. PubMed ID: 31558581

    Lee, H. and Oliver, B. (2018). Non-canonical Drosophila X chromosome dosage compensation and repressive topologically associated domains. Epigenetics Chromatin 11(1): 62. PubMed ID: 30355339

    Grobler, Y., Yun, C. Y., Kahler, D. J., Bergman, C. M., Lee, H., Oliver, B. and Lehmann, R. (2018). Whole genome screen reveals a novel relationship between Wolbachia levels and Drosophila host translation. PLoS Pathog 14(11): e1007445. PubMed ID: 30422992

    Wang, Y., Cho, D. Y., Lee, H., Fear, J., Oliver, B. and Przytycka, T. M. (2018). Reprogramming of regulatory network using expression uncovers sex-specific gene regulation in Drosophila. Nat Commun 9(1): 4061. PubMed ID: 30283019

    Lee, H., Cho, D. Y., Wojtowicz, D., Harbison, S. T., Russell, S., Oliver, B. and Przytycka, T. (2017). Dosage-dependent expression variation suppressed on the Drosophila male X chromosome. G3 (Bethesda). PubMed ID: 29242386

    Yang, H., Basquin, D., Pauli, D. and Oliver, B. (2017). Drosophila melanogaster positive transcriptional elongation factors regulate metabolic and sex-biased expression in adults. BMC Genomics 18(1): 384. PubMed ID: 28521739

    Lee, H., Cho, D.Y., Whitworth, C., Eisman, R., Phelps, M., Roote, J., Kaufman, T., Cook, K., Russell, S., Przytycka, T. and Oliver, B. (2016). Effects of gene dose, chromatin, and network topology on expression in Drosophila melanogaster. PLoS Genet 12: e1006295. PubMed ID: 27599372

    Sun, X., Yang, H., Sturgill, D., Oliver, B., Rabinow, L. and Samson, M. L. (2015). Sxl-dependent, tra/tra2-independent alternative splicing of the Drosophila melanogaster X-Linked gene found in neurons. G3 (Bethesda) [Epub ahead of print]. PubMed ID: 26511498

  • Eric Olson University of Texas Southwestern Medical Center, Department of Molecular Biology, Dallas
    Lee, J. H., Bassel-Duby, R. and Olson, E. N. (2014). Heart- and muscle-derived signaling system dependent on MED13 and Wingless controls obesity in Drosophila. Proc Natl Acad Sci U S A 111: 9491-9496. PubMed ID: 24979807

    Johnson, A. N., Mokalled, M. H., Valera, J. M., Poss, K. D. and Olson, E. N. (2013). Post-transcriptional regulation of myotube elongation and myogenesis by Hoi Polloi. Development 140: 3645-3656. PubMed ID: 23942517

    Johnson, A. N., Mokalled, M. H., Haden, T. N. and Olson, E. N. (2011). JAK/Stat signaling regulates heart precursor diversification in Drosophila. Development 138: 4627-4638. PubMed ID: 21965617

  • Richard Ordway Department of Biology, Penn State University
    Florian, J. R., DeMatte, S. J., Sweeder, D. M., Ordway, R. W. and Kawasaki, F. (2021). Genetic analysis of the Drosophila ESCRT-III complex protein, VPS24, reveals a novel function in lysosome homeostasis. PLoS One 16(5): e0251184. PubMed ID: 33956855

    Strauss, A. L., Kawasaki, F. and Ordway, R. W. (2015). A distinct perisynaptic glial cell type forms tripartite neuromuscular synapses in the Drosophila adult. PLoS One 10: e0129957. PubMed ID: 26053860

    Kawasaki, F., Iyer, J., Posey, L. L., Sun, C. E., Mammen, S. E., Yan, H. and Ordway, R. W. (2011). The DISABLED protein functions in CLATHRIN-mediated synaptic vesicle endocytosis and exoendocytic coupling at the active zone. Proc Natl Acad Sci U S A 108: E222-229. PubMed ID: 21606364

    Danjo, R., Kawasaki, F. and Ordway, R. W. (2011). A tripartite synapse model in Drosophila. PLoS One 6: e17131. PubMed ID: 21359186

    Yu, W., Kawasaki, F. and Ordway, R. W. (2011). Activity-dependent interactions of NSF and SNAP at living synapses. Mol Cell Neurosci 47: 19-27. PubMed ID: 21316453

  • Alana O'Reilly Fox Chase Cancer Center, Philadelphia, PA
    Singh, T., Lee, E. H., Hartman, T. R., Ruiz-Whalen, D. M. and O'Reilly, A. M. (2018). Opposing Action of Hedgehog and Insulin Signaling Balances Proliferation and Autophagy to Determine Follicle Stem Cell Lifespan. Dev Cell 46(6): 720-734 e726. PubMed ID: 30197240

    Henry, R. A., Singh, T., Kuo, Y. M., Biester, A., O'Keefe, A., Lee, S., Andrews, A. J. and O'Reilly, A. M. (2016). Quantitative Measurement of Histone Tail Acetylation Reveals Stage-Specific Regulation and Response to Environmental Changes during Drosophila Development. Biochemistry 55(11): 1663-1672. PubMed ID: 26836402

    Hartman, T. R., Ventresca, E. M., Hopkins, A., Zinshteyn, D., Singh, T., O'Brien, J. A., Neubert, B. C., Hartman, M. G., Schofield, H. K., Stavrides, K. P., Talbot, D. E., Riggs, D. J., Pritchard, C. and O'Reilly, A. M. (2015). Novel tools for genetic manipulation of follicle stem cells in the Drosophila ovary reveal an integrin-dependent transition from quiescence to proliferation. Genetics 199(4): 935-957. PubMed ID: 25680813

  • Teresa Orenic Biological Sciences, University of Illinois, Chicago
    Eksi, S. E., Barmina, O., McCallough, C. L., Kopp, A. and Orenic, T. V. (2018). A Distalless-responsive enhancer of the Hox gene Sex combs reduced is required for segment- and sex-specific sensory organ development in Drosophila. PLoS Genet 14(4): e1007320. PubMed ID: 29634724

    Takaesu, N. T., Bulanin, D. S., Johnson, A. N., Orenic, T. V. and Newfeld, S. J. (2008). A combinatorial enhancer recognized by Mad, TCF and Brinker first activates then represses dpp expression in the posterior spiracles of Drosophila. Dev Biol 313(2): 829-843. PubMed ID: 18068697

    Shroff, S., Joshi, M. and Orenic, T. V. (2007). Differential Delta expression underlies the diversity of sensory organ patterns among the legs of the Drosophila adult. Mech Dev 124(1): 43-58. PubMed ID: 17107776

  • Amir Orian Cell Biology, Technion, Israel
    Erez, N., Israitel, L., Bitman-Lotan, E., Wong, W. H., Raz, G., Cornelio-Parra, D. V., Danial, S., Flint Brodsly, N., Belova, E., Maksimenko, O., Georgiev, P., Druley, T., Mohan, R. D. and Orian, A. (2021). A Non-stop identity complex (NIC) supervises enterocyte identity and protects from premature aging. Elife 10. PubMed ID: 33629655

    Flint Brodsly, N., Bitman-Lotan, E., Boico, O., Shafat, A., Monastirioti, M., Gessler, M., Delidakis, C., Rincon-Arano, H. and Orian, A. (2019). The transcription factor Hey and nuclear lamins specify and maintain cell identity. Elife 8. PubMed ID: 31310235

    Yanku, Y., Bitman-Lotan, E., Zohar, Y., Kurant, E., Zilke, N., Eilers, M. and Orian, A. (2018). Drosophila HUWE1 Ubiquitin Ligase Regulates Endoreplication and Antagonizes JNK Signaling During Salivary Gland Development. Cells 7(10). PubMed ID: 30261639

    Abed, M., Bitman-Lotan, E. and Orian, A. (2018). The Biology of SUMO-Targeted Ubiquitin Ligases in Drosophila Development, Immunity, and Cancer. J Dev Biol 6(1). PubMed ID: 29615551

    Koltun, B., Shackelford, E., Bonnay, F., Matt, N., Reichhart, J. M. and Orian, A. (2017). The SUMO-targeted ubiquitin ligase, Dgrn, is essential for Drosophila innate immunity. Int J Dev Biol 61(3-4-5): 319-327. PubMed ID: 28621429

  • Valerio Orlando Dulbecco Telethon Institute, Epigenetics and Genome Reprogramming Lab, Rome, Italy
    Cernilogar, F. M., Burroughs, A. M., Lanzuolo, C., Breiling, A., Imhof, A. and Orlando, V. (2013). RNA-Interference Components Are Dispensable for Transcriptional Silencing of the Drosophila Bithorax-Complex. PLoS One 8: e65740. PubMed ID: 23785447

    Lo Sardo, F., Lanzuolo, C., Comoglio, F., De Bardi, M., Paro, R., Orlando, V. (2013) PcG-Mediated Higher-Order Chromatin Structures Modulate Replication Programs at the Drosophila BX-C. PLoS Genet 9: e1003283. PubMed ID: 23437006

    Lanzuolo, C. and Orlando, V. (2012). Memories from the polycomb group proteins. Annu Rev Genet 46: 561-589. PubMed ID: 22994356

    Lanzuolo, C., Lo Sardo, F. and Orlando, V. (2012). Concerted epigenetic signatures inheritance at PcG targets through replication. Cell Cycle 11: 1296-1300. PubMed ID: 22421150

    Cernilogar, F. M., et al. (2011). Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila. Nature 480: 391-395. PubMed ID: 22056986

  • William Orr Biological Sciences, Southern Methodist University, Dallas, TX
    Klichko, V.I., Chow, E.S., Kotwica-Rolinska, J., Orr, W.C., Giebultowicz, J.M. and Radyuk, S.N. (2015). Aging alters circadian regulation of redox in Drosophila. Front Genet 6: 83. PubMed ID: 25806044

    Radyuk, S.N., Klichko, V., Sohal, B. H., Radyuk, S. N., Orr, W. C. and Sohal, R. S. (2014). Decrease in cytochrome c oxidase reserve capacity diminishes robustness of Drosophila melanogaster and shortens life span. Biochem J. PubMed ID: 24444354

    Orr, W. C., Radyuk, S. N. and Sohal, R. S. (2013). Involvement of redox state in the aging of Drosophila melanogaster. Antioxid Redox Signal 19: 788-803. PubMed ID: 23458359

    Radyuk, S. N., Klichko, V. I., Michalak, K. and Orr, W. C. (2013). The effect of peroxiredoxin 4 on fly physiology is a complex interplay of antioxidant and signaling functions. FASEB J 27: 1426-1438. PubMed ID: 23271054

    Beaver, L. M., Klichko, V. I., Chow, E. S., Kotwica-Rolinska, J., Williamson, M., Orr, W. C., Radyuk, S. N. and Giebultowicz, J. M. (2012). Circadian regulation of glutathione levels and biosynthesis in Drosophila melanogaster. PLoS One 7: e5045

  • Terry Orr-Weaver Whitehead Institute for Biomedical Research, Cambridge, MA
    Aviles-Pagan, E. E., Hara, M. and Orr-Weaver, T. L. (2021). The GNU subunit of PNG kinase, the developmental regulator of mRNA translation, binds BIC-C to localize to RNP granules. Elife 10. PubMed ID: 34250903

    Aviles-Pagan, E. E., Kang, A. S. W. and Orr-Weaver, T. L. (2020). Identification of New Regulators of the Oocyte-to-Embryo Transition in Drosophila. G3 (Bethesda). PubMed ID: 32690584

    Kwasnieski, J. C., Orr-Weaver, T. L. and Bartel, D. P. (2019). Early genome activation in Drosophila is extensive with an initial tendency for aborted transcripts and retained introns. Genome Res. PubMed ID: 31235656

    Hua, B. L., Bell, G. W., Kashevsky, H., Von Stetina, J. R. and Orr-Weaver, T. L. (2018). Dynamic changes in ORC localization and replication fork progression during tissue differentiation. BMC Genomics 19(1): 623. PubMed ID: 30134926

    Hara, M., Lourido, S., Petrova, B., Lou, H. J., Von Stetina, J. R., Kashevsky, H., Turk, B. E. and Orr-Weaver, T. L. (2018). Identification of PNG kinase substrates uncovers interactions with the translational repressor TRAL in the oocyte-to-embryo transition. Elife 7. PubMed ID: 29480805

    Pinto, B. S. and Orr-Weaver, T. L. (2017). Drosophila protein phosphatases 2A B' Wdb and Wrd regulate meiotic centromere localization and function of the MEI-S332 Shugoshin. Proc Natl Acad Sci U S A. PubMed ID: 29158400

    Hara, M., Petrova, B. and Orr-Weaver, T. L. (2017). Control of PNG kinase, a key regulator of mRNA translation, is coupled to meiosis completion at egg activation. Elife 6. PubMed ID: 28555567

    Alexander, J. L., Beagan, K., Orr-Weaver, T. L. and McVey, M. (2016). Multiple mechanisms contribute to double-strand break repair at rereplication forks in Drosophila follicle cells. Proc Natl Acad Sci U S A [Epub ahead of print]. PubMed ID: 27849606

    Eichhorn, S. W., Subtelny, A. O., Kronja, I., Kwasnieski, J. C., Orr-Weaver, T. L. and Bartel, D. P. (2016). mRNA poly(A)-tail changes specified by deadenylation broadly reshape translation in Drosophila oocytes and early embryos. Elife 5. PubMed ID: 27474798

    Alexander, J. L., Barrasa, M. I. and Orr-Weaver, T. L. (2015). Replication fork progression during re-replication requires the DNA damage checkpoint and double-Strand break repair. Curr Biol 25: 1654-1660. PubMed ID: 26051888

    Nordman, J. T. and Orr-Weaver, T. L. (2015). Understanding replication fork progression, stability, and chromosome fragility by exploiting the Suppressor of Underreplication protein. Bioessays. PubMed ID: 26059810

  • Joe O'Tousa Dept. of Biological Sciences, Galvin Life Science Building, University of Notre Dame, Notre Dame IN
    Mecklenburg, K. L., Weghorst, F. P., Freed, S. A. and O'Tousa, J. E. (2018). Discordant Responses to MAPK Pathway Stimulation Include Axonal Growths in Adult Drosophila Photoreceptors. Front Mol Neurosci 11: 441. PubMed ID: 30564098

    Mecklenburg, K. L., Freed, S. A., Raval, M., Quintero, O. A., Yengo, C. M. and O'Tousa, J. E. (2015). Invertebrate and vertebrate class III myosins interact with MORN repeat-containing adaptor proteins. PLoS One 10(3): e0122502. PubMed ID: 25822849

    Rocha, M., Kimler, K. J., Leming, M. T., Hu, X., Whaley, M. A. and O'Tousa, J. E. (2015). Expression and light-triggered movement of rhodopsins in the larval visual system of mosquitoes. J Exp Biol 218(Pt 9): 1386-1392. PubMed ID: 25750414

    Hu, X., Leming, M. T., Whaley, M. A. and O'Tousa, J. E. (2014). Rhodopsin coexpression in UV photoreceptors of Aedes aegypti and Anopheles gambiae mosquitoes. J Exp Biol 217(Pt 6): 1003-1008. PubMed ID: 24311804

  • Johannes Overgaard Department of Bioscience, Aarhus University, Denmark
    Jorgensen, L. B., Malte, H., Orsted, M., Klahn, N. A. and Overgaard, J. (2021). A unifying model to estimate thermal tolerance limits in ectotherms across static, dynamic and fluctuating exposures to thermal stress. Sci Rep 11(1): 12840. PubMed ID: 34145337

    Andersen, M. K. and Overgaard, J. (2020). Maintenance of hindgut reabsorption during cold exposure is a key adaptation for Drosophila cold tolerance. J Exp Biol. PubMed ID: 31953360

    Andersen, M. K., MacMillan, H. A., Donini, A. and Overgaard, J. (2017). Cold tolerance of Drosophila species is tightly linked to epithelial K+ transport capacity of the Malpighian tubules and rectal pads. J Exp Biol. PubMed ID: 28947500

    MacMillan, H. A., Norgard, M., MacLean, H. J., Overgaard, J. and Williams, C. J. A. (2017). A critical test of Drosophila anaesthetics: Isoflurane and sevoflurane are benign alternatives to cold and CO2. J Insect Physiol 101: 97-106. PubMed ID: 28733237

    Sorensen, J. G., Kristensen, T. N. and Overgaard, J. (2016). Evolutionary and ecological patterns of thermal acclimation capacity in Drosophila: is it important for keeping up with climate change? Curr Opin Insect Sci 17: 98-104. PubMed ID: 27720081

    Olsson, T., MacMillan, H. A., Nyberg, N., Staerk, D., Malmendal, A. and Overgaard, J. (2016). Hemolymph metabolites and osmolality are tightly linked to cold tolerance of Drosophila species: a comparative study. J Exp Biol 219(Pt 16): 2504-2513. PubMed ID: 27307488
  • David Owald Institute of Neurophysiology Charité - Universitätsmedizin Berlin
    Raccuglia, D., Huang, S., Ender, A., Heim, M. M., Laber, D., Suarez-Grimalt, R., Liotta, A., Sigrist, S. J., Geiger, J. R. P. and Owald, D. (2019). Network-specific synchronization of electrical slow-wave oscillations regulates sleep drive in Drosophila. Curr Biol 29(21): 3611-3621. PubMed ID: 31630955

    Ehmann, N., Owald, D. and Kittel, R. J. (2018). Drosophila active zones: From molecules to behaviour. Neurosci Res 127: 14-24. PubMed ID: 29258853

    Perisse, E., Owald, D., Barnstedt, O., Talbot, C. B., Huetteroth, W. and Waddell, S. (2016). Aversive Learning and Appetitive Motivation Toggle Feed-Forward Inhibition in the Drosophila Mushroom Body. Neuron 90(5): 1086-1099. PubMed ID: 27210550

    Owald, D. and Waddell, S. (2015). Olfactory learning skews mushroom body output pathways to steer behavioral choice in Drosophila. Curr Opin Neurobiol 35: 178-184. PubMed ID: 26496148

    Owald, D., Felsenberg, J., Talbot, C. B., Das, G., Perisse, E., Huetteroth, W. and Waddell, S. (2015). Activity of defined mushroom body output neurons underlies learned olfactory behavior in Drosophila. Neuron 86(2): 417-427. PubMed ID: 25864636

  • Return to The Interactive Fly