cAMP-dependent protein kinase 1

REFERENCES (part 1/2)

Abel, T., et al. (1997). Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory. Cell 88: 615-626. 9054501

Adolfsen, B., Saraswati, S., Yoshihara, M. and Littleton, J. T. (2004). Synaptotagmins are trafficked to distinct subcellular domains including the postsynaptic compartment. J. Cell Biol. 166: 249-60. 15263020

Akalal, D. B., Wilson, C. F., Zong, L., Tanaka, N. K., Ito, K. and Davis, R. L. (2006). Roles for Drosophila mushroom body neurons in olfactory learning and memory. Learn Mem 13: 659-668. PubMed Citation: 16980542

Alcedo, J., et al. (1996). The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the Hedgehog signal. Cell 86: 221-232. 8706127

Alcedo, J., Zou, Y. and Noll, M. (2000). Posttranscriptional regulation of Smoothened is part of a self-correcting mechanism in the Hedgehog signaling system. Molec. Cell 6: 457-465. 10983991

Ali, S., et al. (1998). The A kinase anchoring protein is required for mediating the effect of protein kinase A on ROMK1 channels. Proc. Natl. Acad. Sci. 95(17): 10274-8. PubMed Citation: 9707637

Ayaz, D., et al. (2008). Axonal injury and regeneration in the adult brain of Drosophila. J. Neurosci. 28(23): 6010-21. PubMed Citation: 18524906

Bagley, E. E., et al. (2004). GABA transporter currents activated by Protein kinase A excite midbrain neurons during opioid withdrawal. Neuron 45: 433-445. 15694329

Baines, R. A. (2003). Postsynaptic protein kinase A reduces neuronal excitability in response to increased synaptic excitation in the Drosophila CNS. J Neurosci 23: 8664-8672. PubMed Citation: 14507965

Balint-Kurti, P., et al. (1998). Non-autonomous regulation of a graded, PKA-mediated transcriptional activation signal for cell patterning. Development 125(20): 3947-3954. PubMed Citation: 9735356

Baum, B., Li, W. and Perrimon, N. (2000). A cyclase-associated protein regulates actin and cell polarity during Drosophila oogenesis and in yeast. Curr. Biol. 10: 964-973. 10985383

Bauman, A. L., et al. (2006). Dynamic regulation of cAMP synthesis through anchored PKA-adenylyl cyclase V/VI complexes. Mol. Cell 23(6): 925-31. 16973443

Bartsch, D., et al. (1995). Aplysia CREB2 represses long-term facilitation: relief of repression converts transient facilitation into long-term functional and structural change. Cell 83: 979-992. PubMed Citation: 8521521

Bhattacharya, A., Lakhman, S.S. and Singh, S. (2004). Modulation of L-type calcium channels in Drosophila via a pituitary adenylyl cyclase-activating polypeptide (PACAP)-mediated pathway. J. Biol. Chem. 279: 37291-37297. Medline abstract: 15201281

Bhave, G., et al. (2002). cAMP-dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation. Neuron 35: 721-731. 12194871

Bischof, L. J., et al. (1998). Members of the meis1 and pbx homeodomain protein families cooperatively bind a cAMP-responsive sequence (CRS1) from bovine CYP17. J. Biol. Chem. 273(14): 7941-7948. PubMed Citation: 9525891

Blader, P., et al. (1997). The activity of Neurogenin1 is controlled by local cues in the zebrafish embryo. Development 124(22): 4557-4569. PubMed Citation: 9409673

Bouzaiane, E., Trannoy, S., Scheunemann, L., Placais, P. Y. and Preat, T. (2015). Two independent mushroom body output circuits retrieve the six discrete components of Drosophila aversive memory. Cell Rep 11(8): 1280-1292. PubMed ID: 25981036

Brandon, E. P., et al. (1995). Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase. Proc. Natl. Acad. Sci. 92: 8851-8855. PubMed Citation: 7568030

Briggs, L. J., et al. (1998). The cAMP-dependent protein kinase site (Ser312) enhances Dorsal nuclear import through facilitating nuclear localization sequence/importin interaction. J. Biol. Chem. 273(35): 22745-22752. PubMed Citation: 9712906

Burton, K. A., et al. (1997). Type II regulatory subunits are not required for the anchoring-dependent modulation of Ca2+ channel activity by cAMP-dependent protein kinase. Proc. Natl. Acad. Sci. 94(20): 11067-11072. PubMed Citation: 9380760

Cai, X., Gu, Z., Zhong, P., Ren, Y. and Yan, Z. (2002). Serotonin 5-HT1A receptors regulate AMPA receptor channels through inhibiting Ca2+/calmodulin-dependent kinase II in prefrontal cortical pyramidal neurons. J. Biol. Chem. 277(39): 36553-62. 12149253

Carrion, A. M., Mellstrom, B. and Naranjo, J. R. (1998). Protein kinase A-dependent derepression of the human Prodynorphin gene via differential binding to an intragenic silencer element. Mol. Cell. Biol. 18(12): 6921-6929. PubMed Citation: 9819380

Casadio, A., et al. (1999). A transient, neuron-wide form of CREB-mediated long-term facilitation can be stabilized at specific synapses by local protein synthesis. Cell 99: 221-237. PubMed Citation: 10535740

Cervo, L., Mukherjee, S., Bertaglia, A. and Samanin, R. (1997). Protein kinases A and C are involved in the mechanisms underlying consolidation of cocaine place conditioning. Brain Res. 775(1-2): 30-6. 9439825

Chain, D. G., et al. (1995). Persistent activation of cAMP-dependent protein kinase by regulated proteolysis suggests a neuron-specific function of the ubiquitin system in Aplysia. J. Neurosci. 15(11): 7592-603. PubMed Citation: 7472510

Chain, D. G., et al. (1999). Mechanisms for generating the autonomous cAMP-dependent protein kinase required for long-term facilitation in Aplysia. Neuron 22(1): 147-56. PubMed Citation: 10027297

Cheley, S., et al. (1994). Type II regulatory subunits of cAMP-dependent protein kinase and their binding proteins in the nervous system of Aplysia californica. J. Biol. Chem. 269: 2911-20. PubMed Citation: 7905481

Chen, E. H. and Baker. B. S. (1997). Compartmental organization of the Drosophila genital imaginal discs. Development 124: 205-218. PubMed Citation: 9006081

Chen, C., et al. (1998). Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus. Proc. Natl. Acad. Sci. 95: 2349-2354. PubMed Citation: 9482888

Chen, Y., et al. (1999). Mutants of cubitus interruptus that are independent of PKA regulation are independent of hedgehog signaling. Development 126: 3607-3616. PubMed Citation: 10409506

Chen, Y., Yu, F. H., Surmeier, D. J., Scheuer, T. and Catterall, W. A. (2006). Neuromodulation of Na+ channel slow inactivation via cAMP-dependent protein kinase and protein kinase C. Neuron 49(3): 409-20. 16446144

Chen, Y., et al. (2010). G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in Drosophila. Genes Dev. 24(18): 2054-2067. PubMed Citation: 20844016

Cheng, X., et al. (1998). Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase. Proc. Natl. Acad. Sci. 95(17): 9849-9854

Chenouard, N., Xuan, F. and Tsien, R. W. (2020). Synaptic vesicle traffic is supported by transient actin filaments and regulated by PKA and NO. Nat Commun 11(1): 5318. PubMed ID: 33087709

Chheda, M. G., et al. (2001). Phosphorylation of Snapin by PKA modulates its interaction with the SNARE complex. Nature Cell Biology 3: 331-338. 11283605

Cho, R. W., Buhl, L. K., Volfson, D., Tran, A., Li, F., Akbergenova, Y. and Littleton, J. T. (2015). Phosphorylation of Complexin by PKA regulates activity-dependent spontaneous neurotransmitter release and structural synaptic plasticity. Neuron 88: 749-761. PubMed ID: 26590346

Chyb, S., et al. (1999). Modulation of the light response by cAMP in Drosophila photoreceptors. J. Neurosci. 19(20): 8799-8807

Colledge, M., et al. (2000). Targeting of PKA to Glutamate receptors through a MAGUK-AKAP complex. Neuron 27: 107-119.

Collier, L. S., Suyama, K., Anderson, J. H., Scott, M. P. (2004). Drosophila Costal1 mutations are alleles of protein kinase A that modulate hedgehog signaling. Genetics 167(2): 783-96. 15238528

Crocker, A. and Sehgal, A. (2008). Octopamine regulates sleep in Drosophila through protein kinase A-dependent mechanisms. J. Neurosci. 28(38): 9377-85. PubMed Citation: 18799671

Cziko, A.-M. J. et al. (2009). Genetic modifiers of dFMR1 encode RNA granule components in Drosophila. Genetics 182(4): 1051-1060. PubMed Citation: 19487564

Daaka, Y., Luttrell, L. M. and Lefkowitz, R. J. (1997). Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A. Nature 389(6655): 88-91

Dahdal, D., et al. (2010). Drosophila pacemaker neurons require G protein signaling and GABAergic inputs to generate twenty-four hour behavioral rhythms. Neuron 68(5): 964-77. PubMed Citation: 21145008

Dai, P., et al. (1999). Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3. J. Biol. Chem. 274(12): 8143-52

D'Angiolella, V., et al. (2001). Role for cyclin-dependent kinase 2 in mitosis exit. Curr. Bio. 11: 1221-1226. 11516956

Das, S., et al. (1997). NMDA and D1 receptors regulate the phosphorylation of CREB and the induction of c-fos in striatal neurons in primary culture. Synapse 25(3): 227-233

Davis, R. L., et al. (1995). The cyclic AMP system and Drosophila learning. Mol. and Cell. Biochem. 149/150: 271-278

Davis, R. L. (2011). Traces of Drosophila memory. Neuron 70: 8-19. PubMed ID: 21482352

Davis, G. W., DiAntonio, A., Petersen, S. A. and Goodman, C. S. (1998). Postsynaptic PKA controls quantal size and reveals a retrograde signal that regulates presynaptic transmitter release in Drosophila. Neuron 20: 305-315. PubMed Citation: 9491991

Deshpande, G., et al. (2001). Hedgehog signaling in germ cell migration. Cell 106: 759-769. 11572781

Dittmer, P. J., Dell'Acqua, M. L. and Sather, W. A. (2014). Ca(2+)/calcineurin-dependent inactivation of neuronal L-type Ca(2+) channels requires priming by AKAP-anchored protein kinase A. Cell Rep 7: 1410-1416. PubMed ID: 24835998

Diviani, D., et al. (2000). Pericentrin anchors protein kinase A at the centrosome through a newly identified RII-binding domain. Curr. Biol. 10: 417-420.

Drier, E. A., Huang, L. H. and Steward, R. (1999). Nuclear import of the Drosophila Rel protein Dorsal is regulated by phosphorylation. Genes Dev. 13(5): 556-568

Dong, J., et al. (1998a). A phosphorylation site in the Ftz homeodomain is required for activity. EMBO J. 17: 2308-2318

Dong, J. M., et al. (1998b). cAMP-induced morphological changes are counteracted by the activated RhoA small GTPase and the Rho kinase ROKalpha. J. Biol. Chem. 273(35): 22554-22562

Downs, S. M., Hudson, E. R. and Hardie, D. G. (2002). A potential role for AMP-activated protein kinase in meiotic induction in mouse oocytes Dev. Biol. 245: 200-212. 11969266

Efetova, M., Petereit, L., Rosiewicz, K., Overend, G., Haussig, F., Hovemann, B. T., Cabrero, P., Dow, J. A. and Schwarzel, M. (2013). Separate roles of PKA and EPAC in renal function unraveled by the optogenetic control of cAMP levels in vivo. J Cell Sci 126(Pt 3): 778-788. PubMed ID: 23264735

Dransfield, D. T., et al (1997). Ezrin is a cyclic AMP-dependent protein kinase anchoring protein. EMBO J. 16: 35-43

Eide, T., et al. (1998). Molecular cloning, chromosomal localization, and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95. Exp. Cell Res. 238(2): 305-316

Epstein, D. J., et al. (1996). Antagonizing cAMP-dependent protein kinase A in the dorsal CNS activates a conserved Sonic hedgehog signaling pathway. Development 122(9): 2885-94

Esguerra, M., et al. (1994). Cloned Ca(2+)-dependent K+ channel modulated by a functionally associated protein kinase. Nature 369(6481): 563-5

Fan, C. M., et al. (1995). Long-range sclerotome induction by sonic hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway. Cell 81: 457-65

Feliciello, A., et al. (1997). A-kinase anchor protein 75 increases the rate and magnitude of cAMP signaling to the nucleus. Curr. Biol. 7(12): 1011-1014

Fiala, A., Muller, U. and Menzel, R. (1999). Reversible downregulation of protein kinase A during olfactory learning using antisense technique impairs long-term memory formation in the honeybee, Apis mellifera. J Neurosci. 19(22): 10125-34

Firulli, B. A., et al. (2003). PKA, PKC, and the Protein phosphatase 2A influence HAND factor function: A mechanism for tissue-specific transcriptional regulation. Molec. Cell 12: 1225-1237. 14636580

Francis, S. H., and Corbin, J. D. (1994). Structure and function of cyclic nucleotide-dependent protein kinases. Annu. Rev. Physiol. 56: 237-72. PubMed Citation: 8010741

Fraser, I. D. C., et al. (1998). A novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane events. EMBO J. 17: 2261-2272. PubMed Citation: 9545239

Ganguly, A. and Lee, D. (2013). Suppression of inhibitory GABAergic transmission by cAMP signaling pathway: alterations in learning and memory mutants. Eur J Neurosci 37: 1383-1393. PubMed ID: 23387411

Gao, T., et al. (1997). cAMP-dependent regulation of cardiac L-type Ca2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits. Neuron 19(1): 185-196. PubMed Citation: 9247274

Gibson, R. M., Ji-Buechler ,Y. and Taylor, S. S. (1997). Interaction of the regulatory and catalytic subunits of cAMP-dependent protein kinase. Electrostatic sites on the type Ialpha regulatory subunit. J. Biol. Chem. 272(26): 16343-16350. PubMed Citation: 9195940

Goessling, W., et al. (2009). Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell 136(6): 1136-47. PubMed Citation: 19303855

Goldsmith, B. A. and Abrams, T. W. (1992). cAMP modulates multiple K+ currents, increasing spike duration and excitability in Aplysia sensory neurons. Proc. Natl. Acad. Sci. 89: 11481-5. PubMed Citation: 1333612

Goodwin, S. F., et al. (1997). Defective learning in mutants of the Drosophila gene for a regulatory subunit of cAMP-dependent protein kinase. J. Neurosci. 17(22): 8817-8827. PubMed Citation: 9348350

Görner, W., et al. (1998). Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity. Genes Dev. 12: 586-597. PubMed Citation: 9472026

Gourlet, P., Vandermeers, A., Robberecht, P. and Deschodt-Lanckman, M. (1997). Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating peptide (PACAP-27, but not PACAP-38) degradation by the neutral endopeptidase EC Biochem Pharmacol 54(4): 509-515. PubMed ID: 9313778

Gray, P. C., et al. (1998). Primary structure and function of an A kinase anchoring protein associated with calcium channels. Neuron 20(5): 1017-1026

Grieco, D., et al. (1996). Requirement for cAMP-PKA pathway activation by M phase-promoting factor in the transition from mitosis to interphase. Science 271: 1718-1723

Gronholm, M., et al. (2003). Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A. J. Biol. Chem. 278(42): 41167-72. 12896975

Guan, Z., Buhl, L. K., Quinn, W. G. and Littleton, J. T. (2011). Altered gene regulation and synaptic morphology in Drosophila learning and memory mutants. Learn Mem 18: 191-206. PubMed ID: 21422168

Guo, H.-F., et al. (2000). A neurofibromatosis-1-regulated pathway is required for learning in Drosophila. Nature 403: 895-898

Feliciello, A., et al. (1997). A-kinase anchor protein 75 increases the rate and magnitude of cAMP signaling to the nucleus. Curr. Biol. 7(12): 1011-1014

Goodwin, S. F., Del Vecchio, M., Velinzon, K., Hogel, C., Russell, S. R., Tully, T. and Kaiser, K. (1997). Defective learning in mutants of the Drosophila gene for a regulatory subunit of cAMP-dependent protein kinase. J. Neurosci. 17: 8817-8827. 9348350

Hagiwara, M., et al. (1993). Coupling of hormonal stimulation and transcription via the cyclic AMP-responsive factor CREB is rate limited by nuclear entry of protein kinase A. Mol. Cell Biol. 13: 4852-9

Hallier, B., Schiemann, R., Cordes, E., Vitos-Faleato, J., Walter, S., Heinisch, J. J., Malmendal, A., Paululat, A. and Meyer, H. (2016). Drosophila neprilysins control insulin signaling and food intake via cleavage of regulatory peptides. Elife 5. PubMed ID: 27919317 Drosophila. Nature 375(6532): 588-592. PubMed ID: 7791875

Han, S. J., Chen, R., Paronetto, M. P. and Conti, M. (2005). Wee1B is an oocyte-specific kinase involved in the control of meiotic arrest in the mouse. Curr. Biol. 15(18): 1670-6. 16169490

Hammerschmidt, M., Bitgood, M. J. and McMahon, A. P. (1996). Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo. Genes Dev. 10: 647-658

Han, J. D., Baker, N. E. and Rubin, C. S. (1997) Molecular characterization of a novel A kinase anchor protein from Drosophila melanogaster. J. Biol. Chem. 272(42): 26611-26619

Harvie, P. D., Filippova, M. and Bryant, P. J. (1998). Genes expressed in the ring gland, the major endocrine organ of Drosophila melanogaster. Genetics 149(1): 217-231

Haug, L. S., et al. (1999). Phosphorylation of the inositol 1,4,5-trisphosphate receptor by cyclic nucleotide-dependent kinases in vitro and in rat cerebellar slices in situ. J. Biol. Chem. 274(11): 7467-73. 10066812

Hebb, D. O. (1949). The Organization of Behavior. Wiley, New York

Hegde, A. N., Goldberg, A. L. and Schwartz, J. H. (1993). Regulatory subunits of cAMP-dependent protein kinases are degraded after conjugation to ubiquitin: a molecular mechanism underlying long-term synaptic plasticity. Proc. Natl. Acad. Sci. 90(16): 7436-40

Hegde, A. N., et al. (1997). Ubiquitin C-terminal hydrolase is an immediate-early gene essential for long-term facilitation in Aplysia. Cell 89: 115-126

Hendricks, J. C., et al. (2001). A non-circadian role for cAMP signaling and CREB activity in Drosophila rest homeostasis. Nat. Neurosci. 4: 1108-1115. 11687816

Hensch, T. K., et al. (1998). Comparison of plasticity in vivo and in vitro in the developing visual cortex of normal and protein kinase A RIbeta-deficient mice. J. Neurosci. 18(6): 2108-2117

Hoffman, D. A. and Johnston, D. (1998). Downregulation of transient K+ channels in dendrites of hippocampal CA1 pyramidal neurons by activation of PKA and PKC. J. Neurosci. 18(10): 3521-3528

Homayouni, R., Byrne, J. H. and Eskin, A. (1995). Dynamics of protein phosphorylation in sensory neurons of Aplysia. J. Neurosci. 15: 429-38

Howe, A. K. and Juliano, R. L. (2000). Regulation of anchorage-dependent signal transduction by Protein kinase A and p21-activated kinase. Nat. Cell Biol. 2: 593-600. 10980699

Hu, S. C., Chrivia, J. and Ghosh, A. (1999). Regulation of CBP-mediated transcription by neuronal calcium signaling. Neuron 22(4): 799-808

Huang, A. M. and Rubin, G. M. (2000). A misexpression screen identifies genes that can modulate RAS1 pathway signaling in Drosophila melanogaster. Genetics 156(3): 1219-30. 11063696

Huang, G., et al. (2007). Protein kinase A and casein kinases mediate sequential phosphorylation events in the circadian negative feedback loop. Genes Dev. 21(24): 3283-95. PubMed citation: 18079175

Huang, L. J., et al. (1997). D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain. Proc. Natl. Acad. Sci. 94(21): 11184-11189

Huang, Y.-Y., et al. (1995), A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning. Cell 83: 1211-1222

Huang, Y. Y. and Kandel, E. R. (1998). Postsynaptic induction and PKA-dependent expression of LTP in the lateral amygdala. Neuron 21(1): 169-178

Huang, Z. and Kunes, S. (1998). Signals transmitted along retinal axons in Drosophila: Hedgehog signal reception and the cell circuitry of lamina cartridge assembly. Development 125: 3753-3764

Ice, R. J., Wildonger, J., Mann, R. S. and Hiebert, S. W. (2005). Comment on 'Nervy links protein kinase A to plexin-mediated semaphorin repulsion'. Science 309(5734): 558. PubMed citation: 16040690

Imai, T., Suzuki, M. and Sakano, H. (2006). Odorant receptor-derived cAMP signals direct axonal targeting. Science 314(5799): 657-61. Medline abstract: 16990513

Impey, S., et al. (1996). Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus. Neuron 16: 973-982

Impey, S., et al. (1998). Cross talk between ERK and PKA is required for Ca2+ stimulation of CREB-dependent transcription and ERK nuclear translocation. Neuron 21(4): 869-83

Islam, M. S., et al. (1998). In situ activation of the type 2 ryanodine receptor in pancreatic beta cells requires cAMP-dependent phosphorylation. Proc. Natl. Acad. Sci. 95(11): 6145-6150

Jackson, S. M. and Blochlinger, K. (1997). cut interacts with Notch and protein kinase A to regulate egg chamber formation and to maintain germline cyst integrity during Drosophila oogenesis. Development 124: 3663-3672

Jackson, S. M. and Berg, C. A. (2002). An A-kinase anchoring protein is required for Protein kinase A regulatory subunit localization and morphology of actin structures during oogenesis in Drosophila. Development 129: 4423-4433. 12223401

Jia, G., Liu, Y., Yan, W. and Jia, J. (2009). PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation. Development 136: 307-316. PubMed Citation: 19088085

Jia, J., et al. (2002). Shaggy/GSK3 antagonizes Hedgehog signaling by regulating Cubitus interruptus. Nature 416: 548-551. 11912487

Jiang, J. and Struhl, G. (1995). Protein kinase A and Hedgehog signaling in Drosophila limb development. Cell 80 563-572. PubMed Citation: 7867064

Johnson, L. R., et al. (1997). Assembly of AKAP82, a protein kinase A anchor protein, into the fibrous sheath of mouse sperm. Dev. Biol. 192(2): 340-350

Joiner, W. J., Crocker, A., White, B. H. and Sehgal, A. (2006). Sleep in Drosophila is regulated by adult mushroom bodies. Nature 441(7094): 757-60. Medline abstract: 16760980

Joore, J., et al. (1998). Protein kinase A is involved in the induction of early mesodermal marker genes by activin. Mech. Dev. 79(1-2): 5-16. PubMed Citation: 10349616

Kaang, B. K., Kandel, E. R. and Grant, S. G. (1993). Activation of cAMP-responsive genes by stimuli that produce long-term facilitation in Aplysia sensory neurons. Neuron 10: 427-35. PubMed Citation: 8384857

Kalderon, D. and Rubin, G. M. (1988). Isolation and characterization of Drosophila cAMP-dependent protein kinase gene. Genes Dev. 2: 1539-56. PubMed Citation: 3215511

Kameyama, K., et al. (1998). Involvement of a postsynaptic protein kinase A substrate in the expression of homosynaptic long-term depression. Neuron 21(5): 1163-75. PubMed Citation: 9856471

Kiger, J. A., et al. (1999). Transgenic inhibitors identify two roles for Protein Kinase A in Drosophila development. Genetics 152(1): 281-290. PubMed Citation: 10224260

Kiger, J. A. and O'Shea, C. (2001a). Genetic evidence for a protein kinase A/Cubitus interruptus complex that facilitates processing of Cubitus interruptus in Drosophila. Genetics 158: 1157-1166. 11454764

Kiger, J. A., Natzle, J. E. and Green, M. M. (2001b). Hemocytes are essential for wing maturation in Drosophila melanogaster. Proc. Natl. Acad. Sci. 98(18): 10190-5. 11504926

Kikuchi, A. and Williams, L. T. (1996). Regulation of interaction of ras p21 with RalGDS and Raf-1 by cyclic AMP-dependent protein kinase. J. Biol. Chem. 271(1): 588-94. PubMed Citation: 8550624

Kilman, V. L., Zhang, L., Meissner, R. A., Burg, E. and Allada, R. (2009). Perturbing dynamin reveals potent effects on the Drosophila circadian clock. PLoS One 4(4): e5235. PubMed Citation: 19384421

Kilstrup-Nielsen, C., Alessio, M. and Zappavigna, V. (2003). PBX1 nuclear export is regulated independently of PBX-MEINOX interaction by PKA phosphorylation of the PBC-B domain. EMBO J. 22: 89-99. 12505987

Kim, C., Cheng, C. Y., Saldanha, S. A. and Taylor, S. S. (2007). PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation. Cell 130(6): 1032-43. PubMed citation; Online text

Kimura, K.-i., Kodama, A., Hayasaka, Y. and Ohta, T. (2004). Activation of the cAMP/PKA signaling pathway is required for post-ecdysial cell death in wing epidermal cells of Drosophila melanogaster. Development 131: 1597-1606. 14998927

Kotani, S., et al. (1998). PKA and MPF-activated polo-like kinase regulate anaphase-promoting complex activity and mitosis progression. Mol. Cell 1(3): 371-80

Krashes, M. J., Keene, A. C., Leung, B., Armstrong, J. D. and Waddell, S. (2007). Sequential use of mushroom body neuron subsets during drosophila odor memory processing. Neuron 53: 103-115. PubMed Citation: 17196534

Krushel, L. A., et al. (1998). Neural cell adhesion molecule (N-CAM) domains and intracellular signaling pathways involved in the inhibition of astrocyte proliferation. Proc. Natl. Acad. Sci. 95: 2592-2596

Kula-Eversole, E., Nagoshi, E., Shang, Y., Rodriguez, J., Allada, R. and Rosbash, M. (2010). Surprising gene expression patterns within and between PDF-containing circadian neurons in Drosophila. Proc. Natl. Acad. Sci. 107: 13497-502. PubMed Citation: 20624977

Lane-Ladd, S. B., et al. (1997). CREB (cAMP response element-binding protein) in the locus coeruleus: biochemical, physiological, and behavioral evidence for a role in opiate dependence. J. Neurosci. 17(20): 7890-7901

Lane, M. E. and Kalderon, D. (1993). Genetic investigation of cAMP-dependent protein kinase function in Drosophila development. Genes Dev. 7: 1229-1243

Lane, M. E. and Kalderon, D. (1994). RNA localization along the anteroposterior axis of the Drosophila oocyte requires PKA-mediated signal transduction to direct normal microtubule organization. Genes Dev. 8: 2986-2995

Lane, M. E. and Kalderon, D. (1995). Localization and functions of protein kinase A during Drosophila oogenesis. Mech. Dev. 49: 191-200

Lee, H.-K., et al. (2000). Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity. Nature 405: 955-959

Lee, H., Rezai-Zadeh, N. and Seto, E. (2004). Negative regulation of histone deacetylase 8 activity by cyclic AMP-dependent protein kinase A. Mol. Cell. Biol. 24(2): 765-73. 14701748

Lee, P. T., Lin, G., Lin, W. W., Diao, F., White, B. H. and Bellen, H. J. (2018). A kinase-dependent feedforward loop affects CREBB stability and long term memory formation. Elife 7. PubMed ID: 29473541

Lepage, T., et al. (1995). Signal transduction by cAMP-dependent protein kinase A in Drosophila limb patterning. Nature 373: 711-715

Lester, L. B., Langeberg, L. K., Scott, J. D. (1997). Anchoring of protein kinase A facilitates hormone-mediated insulin secretion. Proc. Natl. Acad. Sci. 94(26): 14942-14947

Levine, J. D., et al. (1994). Altered circadian pacemaker functions and cyclic AMP rhythms in the Drosophila learning mutant dunce. Neuron 13: 967-74

Leyssen, M. and Hassan, B. A. (2007). A fruitfly's guide to keeping the brain wired. EMBO Rep. 8: 46-50. PubMed Citation: 17203102

Li, W., et al. (1995). Function of protein kinase A in Hedgehog signal transduction and Drosophila imaginal disc development. Cell 80: 553-562

Li, W., Tully, T. and Kalderon, D. (1996). Effects of a conditional Drosophila PKA mutant on olfactory learning and memory. Learn Mem. 2(6): 320-33

Li, X, Fetter, R., Schwabe, T., Jung, C., Liu, L., Steller, H. and Gaul, U. (2021). The cAMP effector PKA mediates Moody GPCR signaling in Drosophila blood-brain barrier formation and maturation. Elife 10. PubMed ID: 34382936

Li, Y., Guo, F., Shen, J., Rosbash, M. (2014). PDF and cAMP enhance Per stability in Drosophila clock neurons. Proc Natl Acad Sci U S A 111: E1284-1290. PubMed ID: 24707054

Li, Z., Rossi, E., Hoheisel, J., Kalderon, D. and Rubin, C. (1999). Generation of a novel A kinase anchoring protein and a myristoyalted alanine-rich C kinase substrate-linked analog from a single gene. J. Biol. Chem. 274: 27191-27200. 10480936

Liao, X., et al. (1999). Activation of protein kinase A contributes to the expression but not the induction of long-term hyperexcitability caused by axotomy of Aplysia sensory neurons. J. Neurosci. 19(4): 1247-56

Lim, J., Sabandal, P. R., Fernandez, A., Sabandal, J. M., Lee, H. G., Evans, P. and Han, K. A. (2014). The Octopamine receptor Octβ2R regulates ovulation in Drosophila melanogaster. PLoS One 9: e104441. PubMed ID: 25099506

Liou, H. H., Zhou, S. S. and Huang, C. L. (1999). Regulation of ROMK1 channel by protein kinase A via a phosphatidylinositol 4,5-bisphosphate-dependent mechanism. Proc. Natl. Acad. Sci. 96(10):5820-5. PubMed ID: 10318968

Liu, X., Krause, W. C. and Davis, R. L. (2007). GABAA receptor RDL inhibits Drosophila olfactory associative learning. Neuron 56: 1090-1102. PubMed ID: 18093529

Liu, X. and Davis, R. L. (2009). The GABAergic anterior paired lateral neuron suppresses and is suppressed by olfactory learning. Nat Neurosci 12: 53-59. PubMed ID: 19043409

Lu, Y., et al. (2007). The AKAP Yu is required for olfactory long-term memory formation in Drosophila. Proc. Natl. Acad. Sci. USA 104(34): 13792-13797. PubMed Citation: 17690248

Majercak, J., Kalderon, D. and Edery, I. (1997). Drosophila melanogaster deficient in protein kinase A manifests behavior-specific arrhythmia but normal clock function. Mol. Cell. Biol. 17(10): 5915-5922

Mansuy, I. M., et al. (1998). Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory. Cell 92: 39-49

Marks, S. A. and Kalderon, D. (2011). Regulation of mammalian Gli proteins by Costal 2 and PKA in Drosophila reveals Hedgehog pathway conservation. Development 138(12): 2533-42. PubMed Citation: 21610030

Martin, D. E., Soulard, A. and Hall, M. N. (2004). TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1. Cell 119: 969-979. 15620355

Martin, S. G. and St Johnston, D. (2003). A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity. Nature 421(6921): 379-84. 12540903

Marx, S. O., et al. (2000). PKA phosphorylation dissociates FKBP12.6 from the calcium release Channel (ryanodine receptor): defective regulation in failing hearts. Cell 101: 365-376

Masai, I., et al. (2005). The hedgehog-PKA pathway regulates two distinct steps of the differentiation of retinal ganglion cells: the cell-cycle exit of retinoblasts and their neuronal maturation. Development 132(7): 1539-53. 15728672

McGuire, S. E., Le, P. T. and Davis, R. L. (2001). The role of Drosophila mushroom body signaling in olfactory memory. Science 293: 1330-1333. PubMed Citation: 11397912

Meima, M. E. and Schaap, P. (1999). Fingerprinting of adenylyl cyclase activities during Dictyostelium development indicates a dominant role for adenylyl cyclase B in terminal differentiation. Dev. Biol. 212(1): 182-190

Meléndez, A., Li, W. and Kalderon, D. (1995). Activity, expression and function of a second Drosophila protein kinase A catalytic subunit gene. Genetics 141: 1507-20

Methot, N. and Basler, K. (1999). Hedgehog controls limb development by regulation the activities of distinct transcription activator and repressor forms of Cubitus interruptus. Cell 96: 819-831

Michels, B., et al. (2011). Cellular site and molecular mode of synapsin action in associative learning. Learn Mem. 18(5): 332-44. PubMed Citation: 21518740

Miller, M. J., et al. (1998). Differential effects of protein kinase A on Ras effector pathways. Mol. Cell. Biol. 18(7): 3718-3726

Moita, M. A., Lamprecht, R., Nader, K. and LeDoux, J. E. (2002) A-kinase anchoring proteins in amygdala are involved in auditory fear memory. Nat. Neurosci. 5: 837-838. PubMed Citation: 12172550

Mohanty, S., et al. (2001). Regulated protein degradation controls PKA function and cell-type differentiation in Dictyostelium. Genes Dev. 15: 1435-1448. 11390363

Mondal, B. C., et al. (2011). Interaction between differentiating cell- and niche-derived signals in hematopoietic progenitor maintenance. Cell 147(7): 1589-600. PubMed Citation: 22196733

Monnier, D. and Loeffler, J. P. (1998). Pituitary adenylate cyclase-activating polypeptide stimulates proenkephalin gene transcription through AP1- and CREB-dependent mechanisms. DNA Cell Biol. 17(2): 151-159

Moon, C., et al. (1998). Calcium-sensitive particulate guanylyl cyclase as a modulator of cAMP in olfactory receptor neurons. J. Neurosci. 18(9): 3195-3205

Moore, M. S., et al. (1998). Ethanol intoxication in Drosophila: genetic and pharmacological evidence for regulation by the cAMP signaling pathway. Cell 93: 997-1007

Muller, U. (1997). Neuronal cAMP-dependent protein kinase type II is concentrated in mushroom bodies of Drosophila melanogaster and the honeybee Apis mellifera. J. Neurobiol. 33(1): 33-44.

Muller, U. and Carew, T. J. (1998). Serotonin induces temporally and mechanistically distinct phases of persistent PKA activity in Aplysia sensory neurons. Neuron 21(6): 1423-34

Müller, U. (2000). Prolonged activation of cAMP-dependent protein kinase during conditioning induces long-term memory in honeybees. Neuron 27: 159-168. PubMed ID: 10939339

Muniz, M., et al. (1997). Protein kinase A activity is required for the budding of constitutive transport vesicles from the trans-golgi network. Proc. Natl. Acad. Sci. 94(26): 14461-14466

Murphy, J. G., Sanderson, J. L., Gorski, J. A., Scott, J. D., Catterall, W. A., Sather, W. A. and Dell'Acqua, M. L. (2014). AKAP-anchored PKA maintains neuronal L-type calcium channel activity and NFAT transcriptional signaling. Cell Rep 7: 1577-1588. PubMed ID: 24835999

Continued: cAMP-dependent protein kinase 1 - References part 2/2

cAMP-dependent protein kinase 1: Biological Overview | Evolutionary Homologs | Regulation | Protein Interactions | Developmental Biology | Effects of Mutation

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