ventral nervous system defective


Apergis, G. A., et al. (1998). A novel nk-2-related transcription factor associated with human fetal liver and hepatocellular carcinoma. J. Biol. Chem. 273(5): 2917-2925. PubMed Citation: 9446603

Ashraf, S. I. and Ip, Y. T. (2001). The Snail protein family regulates neuroblast expression of inscuteable and string, genes involved in asymmetry and cell division in Drosophila. Development 128: 4757-4767. 11731456

Barth, K. A. and Wilson, S. W. (1995). Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain. Development 121: 1755-1768. PubMed Citation: 7600991

Bery, A., Martynoga, B., Guillemot, F., Joly, J. S. and Retaux, S. (2013). Characterization of enhancers active in the mouse embryonic cerebral cortex suggests Sox/Pou cis-regulatory logics and heterogeneity of cortical progenitors. Cereb Cortex. PubMed ID: 23720416

Bober, E., et al. (1994). A novel NK-related mouse homeobox gene: expression in central and peripheral nervous structures during embryonic development. Dev. Biol. 162: 288-303. PubMed Citation: 7510254

Briscoe, J., et al. (1999). Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling. Nature 398(6728): 622-7. PubMed Citation: 10217145

Briscoe, J., et al. (2000). A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube. Cell 101: 435-445. PubMed Citation: 10830170

Brody, T., et al. (2012). Use of a Drosophila genome-wide conserved sequence database to identify functionally related cis-regulatory enhancers. Dev. Dyn. 241(1): 169-89. PubMed Citation: 22174086

Broihier, H. T., Kuzin, A., Zhu, Y., Odenwald, W. and Skeath, J. B. (2004). Drosophila homeodomain protein Nkx6 coordinates motoneuron subtype identity and axonogenesis. Development 131: 5233-5242. 15456721

Buescher, M., Hing, F. S. and Chia, W. (2002). Formation of neuroblasts in the embryonic central nervous system of Drosophila melanogaster is controlled by SoxNeuro. Development 129: 4193-4203. 12183372

Catena, R., Tiveron, C., Ronchi, A., Porta, S., Ferri, A., Tatangelo, L., Cavallaro, M., Favaro, R., Ottolenghi, S., Reinbold, R., Scholer, H. and Nicolis, S. K. (2004). Conserved POU binding DNA sites in the Sox2 upstream enhancer regulate gene expression in embryonic and neural stem cells. J Biol Chem 279: 41846-41857. PubMed ID: 15262984

Chu, H., et al. (1998). Formation and specification of ventral neuroblasts is controlled by vnd in Drosophila neurogenesis. Genes Dev. 12: 3613-3624. PubMed Citation: 9832512

Cinnamon, E., et al. (2008), Multiple RTK pathways downregulate Groucho-mediated repression in Drosophila embryogenesis. Development 135: 829-837. PubMed Citation: 18216172

Corbin, J. G., et al. (2003). Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development 130: 4895-4906. 12930780

Cowden, J. and Levine, M. (2003). Ventral dominance governs sequential patterns of gene expression across the dorsal-ventral axis of the neuroectoderm in the Drosophila embryo. Dev. Biol. 262: 335-349. 14550796

Craven, S. E., et al. (2004). Gata2 specifies serotonergic neurons downstream of Sonic hedgehog. Development 131: 1165-1173. PubMed Citation: 14973276

D'Alessio, M. D. and Frasch, M. (1996). msh may play a conserved role in dorsoventral patterning of the neuroectoderm and mesoderm. Mech. Dev. 58: 217-231. PubMed Citation: 8887329

Denes, A. S., et al. (2007). Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in bilateria. Cell 129(2): 277-88. Medline abstract: 17448990

Dominguez, M. H., Ayoub, A. E. and Rakic, P. (2012). POU-III transcription factors (Brn1, Brn2, and Oct6) influence neurogenesis, molecular identity, and migratory destination of upper-layer cells of the cerebral cortex. Cereb Cortex. PubMed ID: 22892427

Doyle, M. J., Loomis, Z. L. and Sussel, L. (2007). Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet. Development 134(3): 515-23. Medline abstract: 17202186

Ericson, J., et al. (1997). Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell 90(1): 169-180. PubMed Citation: 9230312

Estes, P., Mosher, J. and Crews, S. T. (2001). Drosophila Single-minded represses gene transcription by activating the expression of repressive factors. Dev. Biol. 232: 157-175. PubMed Citation: 11254355

Fu, H., et al. (2002). Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation. Development 129: 681-693. 11830569

Gabay, L., et al. (1996). EGF receptor signaling induces pointed P1 and inactivates Yan protein in the Drosophila embryonic ventral ectoderm. Development 122: 3355-3362. 8951052

Gauchat, D., et al. (2000). Evolution of Antp-class genes and differential expression of Hydra Hox/paraHox genes in anterior patterning. Proc. Natl. Acad. Sci. 97: 4493-4498. PubMed Citation: 10781050

Goldstein, R. E., et al. (2005). An eh1-like motif in Odd-skipped mediates recruitment of Groucho and repression in vivo. Mol. Cell. Biol. 25(24): 10711-20. 16314497

Grens, A., et al. (1996). CnNK-2, an NK-2 homeobox gene, has a role in patterning the basal end of the axis in hydra. Dev. Biol. 180: 473-488. PubMed Citation: 8954720

Gruschus, J. M., et al. (1997). Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity. Biochemistry 36(18): 5372-80. PubMed Citation: 9154919

Guazzi, S., Price, M., De Felice, M., Damante, G., Mattei, M.-G. and Di Lauro, R. (1990). Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity. EMBO J. 9: 3631-3639. PubMed Citation: 1976511

Hadrys, T., et al. (1998). Nkx5-1 controls semicircular canal formation in the mouse inner ear. Development 125(1): 33-39. PubMed Citation: 9389661

Hochstim, C., Deneen, B., Lukaszewicz, A., Zhou, Q. and Anderson, D. J. (2008). Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code. Cell 133(3): 510-22. PubMed Citation: 18455991

Holland, L. Z., et al. (1998). Characterization and developmental expression of AmphiNk2-2, an NK2 class homeobox gene from Amphioxus. (Phylum Chordata; Subphylum Cephalochordata). Dev Genes Evol. 208(2): 100-5

Butt, S. J., et al. (2008). The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes. Neuron 59(5): 722-32. PubMed Citation: 18786356

Hu, B. Y., et al. (2009). Human oligodendrocytes from embryonic stem cells: conserved SHH signaling networks and divergent FGF effects. Development 136(9): 1443-52. PubMed Citation: 19363151

Inoue, F., Kurokawa, D., Takahashi, M. and Aizawa, S. (2012). Gbx2 directly restricts Otx2 expression to forebrain and midbrain, competing with class III POU factors. Mol Cell Biol 32: 2618-2627. PubMed ID: 22566684

Jimenez, F., et al. (1995). vnd, a gene required for eurly neurogenesis of Drosophila, encodes a homeodomain protein. EMBO J. 14: 3487-95. PubMed Citation: 7628450

Kim, D. S., Matsuda, T. and Cepko, C. L. (2008). A core paired-type and POU homeodomain-containing transcription factor program drives retinal bipolar cell gene expression. J. Neurosci. 28(31): 7748-64. PubMed Citation: 18667607

Kim, H.J., Ahn, H.J., Lee, S., Kim, J.H., Park, J., Jeon, S.H. and Kim, S.H. (2015). Intrinsic dorsoventral patterning and extrinsic EGFR signaling genes control glial cell development in the Drosophila nervous system. Neuroscience 307:242-52. PubMed ID: 26318336

Kim, Y. and Nirenberg, M. (1989). Drosophila NK-homeobox genes. Proc. Natl. Acad. Sci. 86: 7716-7720. PubMed Citation: 2573058

Kitamura, K., et al (1997). Expression patterns of Brx1 (Rieg gene), Sonic hedgehog, Nkx2.2, Dlx1 and Arx during zona limitans intrathalamica and embryonic ventral lateral geniculate nuclear formation. Mech. Dev. 67(1): 83-96

Kohtz, J. D., et al. (1998). Regionalization within the mammalian telencephalon is mediated by changes in responsiveness to Sonic Hedgehog. Development 125(24): 5079-5089

Kramatschek, B. and Campos-Ortega, J.A. (1994) Neuroecotdermal transcription of the Drosophila neurogenic genes E(spl) and HLH-m5 is regulated by proneural genes. Development 120: 815-826. PubMed Citation: 7600959

Kuzin, A., Kundu, M., Ekatomatis, A., Brody, T. and Odenwald, W. F. (2009). Conserved sequence block clustering and flanking inter-cluster flexibility delineate enhancers that regulate nerfin-1 expression during Drosophila CNS development. Gene Expr. Patterns. 9(2): 65-72. PubMed Citation: 19056518

Lee, S.-K., et al. (2004). Analysis of embryonic motoneuron gene regulation: derepression of general activators function in concert with enhancer factors. Development 131: 3295-3306. 15201216

Lowe, C. J., et al. (2003). Anteroposterior patterning in hemichordates and the origins of the chordate nervous system. Cell 113: 853-865. 12837244

Ma, Y., et al. (1998). Gene regulatory functions of Drosophila fish-hook, a high mobility group domain Sox protein. Mech. Dev. 73(2): 169-82. Medline abstract: 9622621

Markstein, M., et al. (2004). A regulatory code for neurogenic gene expression in the Drosophila embryo. Development 131: 2387-2394. 15128669

McDonald, J. A., et al. (1998). Dorsoventral patterning in the Drosophila central nervous system: the vnd homeobox gene specifies ventral column identity. Genes Dev. 12: 3603-3612. PubMed Citation: 9832511

McKinsey, G. L., Lindtner, S., Trzcinski, B., Visel, A., Pennacchio, L. A., Huylebroeck, D., Higashi, Y. and Rubenstein, J. L. (2013). Dlx1&2-dependent expression of Zfhx1b (Sip1, Zeb2) regulates the fate switch between cortical and striatal interneurons. Neuron 77: 83-98. PubMed ID: 23312518

Meier, S., Sprecher, S. G., Reichert, H. and Hirth, F. (2006). ventral veins lacking is required for specification of the tritocerebrum in embryonic brain development of Drosophila. Mech. Dev. 123(1): 76-83. Medline abstract: 16326080

Mellerick, D. and Nirenberg, M. (1995). Dorsal-ventral patterning genes restrict NK2 homeobox gene expression to the ventral half of the central nervous system of Drosophila embryos. Dev. Biol. 171: 306-316. PubMed Citation: 7556915

Mellerick, D. M. and Modica, V. (2002). Regulated vnd expression is required for both neural and glial specification in Drosophila. J. Neurobiol. 50(2): 118-36. 11793359

Minoo, P., et al. (1999). Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos. Dev. Biol. 209(1): 60-71

Mizuno, K., Gonzalez, F. J. and Kimura, S. (1991). Thyroid-specific enhancer-binding protein (T/EBP): cDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1. Mol Cell Biol. 10: 4927-4933

Mizutani, C. M., Meyer, N., Roelink, H. and Bier, E. (2006). Threshold-dependent BMP-mediated repression: a model for a conserved mechanism that patterns the neuroectoderm. PLoS Biol. 4(10): e313. Medline abstract: 16968133

Muhr, J., et al. (2001). Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube. Cell 104: 861-873. 11290324

Nery, S., et al. (2001). Sonic hedgehog contributes to oligodendrocyte specification in the mammalian forebrain. Development 128: 527-540. 11171336

Nóbrega-Pereira, S., et al. (2008). Postmitotic Nkx2-1 controls the migration of telencephalic interneurons by direct repression of guidance receptors. Neuron 59(5): 733-45. PubMed Citation: 18786357

Orian, A., et al. (2007). A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development. Proc. Natl. Acad. Sci. 104(40): 15771-6. PubMed Citation: 17898168

Overton, P. M., Meadows, L. A., Urban, J. and Russell, S. (2002). Evidence for differential and redundant function of the Sox genes Dichaete and SoxN during CNS development in Drosophila. Development 129: 4219-4228. 12183374

Pabst, O., Herbrand, H. and Arnold, H. H. (1998). Nkx2-9 is a novel homeobox transcription factor which demarcates ventral domains in the developing mouse CNS. Mech. Dev. 73(1): 85-93

Pabst, O., et al. (2000). NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue. EMBO J. 19: 2015-2023

Pabst, O., et al. (2003). Targeted disruption of the homeobox gene Nkx2.9 reveals a role in development of the spinal accessory nerve. Development 130: 1193-1202. 12571110

Pattyn, A., et al. (2003). Complementary roles for Nkx6 and Nkx2 class proteins in the establishment of motoneuron identity in the hindbrain. Development 130: 4149-4159. 12874134

Pera, E. M. and Kessel, M. (1997). Patterning of the chick forebrain anlage by the prechordal plate. Development 124(20): 4153-4162

Pera, E. M. and Kessel, M. (1998). Demarcation of ventral territories by the homeobox gene NKX2.1 during early chick development. Dev. Genes Evol. 208: 168-171

Price, M., et al. (1992). Regional expression of the homeobox gene Nkx-2.2 in the developing mammalian forebrain. Neuron 8: 241-55

Qiu, M., et al. (1998). Control of anteroposterior and dorsoventral domains of Nkx-6.1 gene expression relative to other Nkx genes during vertebrate CNS development. Mech. Dev. 72(1-2): 77-88

Reecy, J. M., et al. (1997). Chicken nkx-2.8: A novel homeobox gene expressed in early heart progenitor cells and pharyngeal pouch-2 and -3 endoderm. Dev. Biol. 188(2):295-311

Rinkwitz-Brandt, S., et al. (1995). Distinct temporal expression of mouse Nkx-5.1 and Nkx-5.2 homeobox genes during brain and ear development. Mech Dev 52: 371-381

Rohr, K. B., et al. (2001). The nodal pathway acts upstream of hedgehog signaling to specify ventral telencephalic identity. Neuron 29: 341-351. 11239427

Rouault, H., et al. (2010). Genome-wide identification of cis-regulatory motifs and modules underlying gene coregulation using statistics and phylogeny. Proc. Natl. Acad. Sci. 107: 14615-14620. PubMed Citation: 20671200

Saha, M. S., et al. (1993). A Xenopus homebox gene defines dorsal-ventral domains in the developing brain. Development 118(1): 193-202

Sander, M., et al. (2000). Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas. Development 127: 5533-5540

Saunders, H. H., Koizumi, K., Odenwald, W. and Nirenberg, M. (1998). Neuroblast pattern formation: regulatory DNA that confers the vnd/NK-2 homeobox gene pattern on a reporter gene in transgenic lines of Drosophila. Proc. Natl. Acad. Sci. 95(14): 8316-8321. PubMed Citation: 9653184

Schafer, M., et al. (2005). Hedgehog and retinoid signalling confines nkx2.2b expression to the lateral floor plate of the zebrafish trunk. Mech. Dev. 122(1): 43-56. 15582776

Schroeder, M. D., et al. (2004). Transcriptional control in the segmentation gene network of Drosophila. PLoS Biol 2: E271. PubMed Citation: 15340490

Schulz, R. A. and Gajewski, K. (1999). Ventral neuroblasts and the heartless FGF receptor are required for muscle founder cell specification in Drosophila. Oncogene 18(48): 6818-23. PubMed Citation: 10597291

Seibert, J. and Urbach, R. (2010). Role of en and novel interactions between msh, ind, and vnd in dorsoventral patterning of the Drosophila brain and ventral nerve cord. Dev. Biol. 346(2): 332-45. PubMed Citation: 20673828

Shao, X., Koizumi, K., Nosworthy, N., Tan, D.-P., Odenwald, W. and Nirenberg, M. (2002). Regulatory DNA required for vnd/NK-2 homeobox gene expression pattern in neuroblasts. Proc. Natl. Acad. Sci. 99: 113-117. 11752402

Shimamura, K., et al. (1995). Longitudinal organization of the anterior neural plate and neural tube. Development 121: 3923-3933

Skeath, J. B., Panganiban, G. F. and Carroll, S. B. (1994). The ventral nervous system defective gene controls proneural gene expression at two distinct steps during neuroblast formation in Drosophila. Development 120: 1517-24. PubMed Citation: 8050360

Smith, S. T. and Jaynes, J. B. (1996). A conserved region of Engrailed, shared among all en-, gsc-, Nk1-, Nk2- and msh-class homeoproteins, mediates active transcriptional repression in vivo. Development 122(10): 3141-3150

Soula, C., et al. (2001). Distinct sites of origin of oligodendrocytes and somatic motoneurons in the chick spinal cord: oligodendrocytes arise from Nkx2.2-expressing progenitors by a Shh-dependent mechanism. Development 128: 1369-1379. 11262237

Sprecher, S. G., Urbach, R., Technau, G. M., Rijli, F. M., Reichert, H. and Hirth, F. (2006). The columnar gene vnd is required for tritocerebral neuromere formation during embryonic brain development of Drosophila. Development 133(21): 4331-9. Medline abstract: 17038518

Stathopoulos, A. and Levine, M. (2002). Linear signaling in the Toll-Dorsal pathway of Drosophila: activated Pelle kinase specifies all threshold outputs of gene expression while the bHLH protein Twist specifies a subset. Development 129: 3411-3419. 12091311

Sugimori, M., et al. (2008). Ascl1 is required for oligodendrocyte development in the spinal cord. Development 135: 1271-1281. PubMed Citation: 18287202

Sussel, L., et al. (1998). Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development 125(12): 2213-2221. PubMed Citation: 9584121

Sussel, L., et al. (1999). Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum. Development 126: 3359-3370. PubMed Citation: 10393115

Thomsen, S., et al. (2004). Control of foot differentiation in Hydra: in vitro evidence that the NK-2 homeobox factor CnNK-2 autoregulates its own expression and uses pedibin as target gene. Mech. Dev. 121: 195-204. 15037320

Tsao, D. H. H., et al. (1994). Elongation of helix III of the NK-2 homeodomain upon binding to DNA: a secondary structure study by NMR. Biochemistry 33: 15053-60. PubMed Citation: 7999763

Tsao, D. H., et al. (1998). The three-dimensional solution structure of the NK-2 homeodomain from Drosophila. J. Mol. Biol. 251(2): 297-307. PubMed Citation: 7643404

Uhler, J., et al. (2002). Nk6, a novel Drosophila homeobox gene regulated by vnd. Mech. Dev. 116: 105-116. 12128210

Uhler, J., Zhang, H., Syu, L. J. and Mellerick, D. M. (2007). The Nk-2 box of the Drosophila homeodomain protein, Vnd, contributes to its repression activity in a Groucho-dependent manner. Mech. Dev. 124(1): 1-10. Medline abstract: 17070676

Urbach, R. and Technau, G. M. (2003). Segment polarity and DV patterning gene expression reveals segmental organization of the Drosophila brain. Development 130: 3607-3620. 12835379

Urbach, R., Volland, D., Seibert, J. and Technau, G. M. (2006). Segment-specific requirements for dorsoventral patterning genes during early brain development in Drosophila. Development 133(21): 4315-30. Medline abstract: 17038517

Vokes, S. A., et al. (2007). Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning. Development 134(10): 1977-89. Medline abstract: 17442700

Von Ohlen, T. and Doe, C. Q. (2000). Convergence of Dorsal, Dpp, and Egfr signaling pathways subdivides the Drosophila neuroectoderm into three dorsal-ventral columns. Dev. Bio. 224: 362-372. PubMed Citation: 10926773

Von Ohlen, T. L. and Moses, C. (2009). Identification of Ind transcription activation and repression domains required for dorsoventral patterning of the CNS. Mech. Dev. 126: 552-562. PubMed Citation: 19348939

Venkatesh, T. V., et al. (1999). Sequence and developmental expression of amphioxus AmphiNk2-1: insights into the evolutionary origin of the vertebrate thyroid gland and forebrain. Dev. Genes Evol. 209(4): 254-9. PubMed Citation: 10079369

Wang, H., Lei, Q., Oosterveen, T., Ericson, J. and Matise, M. P. (2011). Tcf/Lef repressors differentially regulate Shh-Gli target gene activation thresholds to generate progenitor patterning in the developing CNS. Development 138(17): 3711-21. PubMed Citation: 21775418

Wang, L. H., Chmelik, R., Tang, D. and Nirenberg, M. (2005). Identification and analysis of Vnd/NK-2 homeodomain binding sites in genomic DNA. Proc. Natl. Acad. Sci. 102(20): 7097-102. 15870192

Weiler, S., et al. (1998). Site-directed mutations in the vnd/NK-2 homeodomain. Basis Of variations in structure and sequence-specific DNA binding. J. Biol. Chem. 273(18): 10994-11000. PubMed Citation: 9556579

Weiss, J. B., Ohlen, T. V., Mellerick, D. M., Dressler, G., Doe, C. Q. and Scott, M. P. (1998). Dorsoventral patterning in the Drosophila central nervous system: the intermediate neuroblasts defective homeobox gene specifies intermediate column identity. Genes Dev 12: 3591-3602. PubMed Citation: 9832510

White, K., DeCelles, N. L. and Enlow, T. C. (1983). Genetic and developmental analysis of the locus vnd in Drosophila melanogaster. Genetics 104(3): 433-48. PubMed Citation: 6411520

Xiang, B., et al. (1998). Structural basis of an embryonically lethal single Ala --> Thr mutation in the vnd/NK-2 homeodomain. Proc. Natl. Acad. Sci. 95(13): 7412-7416

Yagi, Y., Suzuki, T. and Hayashi, S. (1998). Interaction between Drosophila EGF receptor and vnd determines three dorsoventral domains of the neuroectoderm. Development 125(18): 3625-3633. PubMed Citation: 9716528

Yang, L., Rastegar, S. and Strähle U. (2010). Regulatory interactions specifying Kolmer-Agduhr interneurons. Development 137(16): 2713-22. PubMed Citation: 20610488

Yu, Z., Syu, L. J. and Mellerick, D. M. (2005). Contextual interactions determine whether the Drosophila homeodomain protein, Vnd, acts as a repressor or activator. Nucleic Acids Res. 33(1): 1-12. Medline abstract: 15640442

Zhang, Y., et al. (2007). GATA and Nkx factors synergistically regulate tissue-specific gene expression and development in vivo. Development 134: 189-198. Medline abstract: 17164424

Zhao, G. and Skeath, J. B. (2002). The Sox-domain containing gene Dichaete/fish-hook acts in concert with vnd and ind to regulate cell fate in the Drosophila neuroectoderm. Development 129: 1165-1174. 11874912

Zhao, G., Wheeler, S. R. and Skeath, J. B. (2007). Genetic control of dorsoventral patterning and neuroblast specification in the Drosophila central nervous system. Int. J. Dev. Biol. 51(2): 107-15. Medline abstract: 17294361

Zhao, G., Boekhoff-Falk, G., Wilson, B. A. and Skeath, J. B. (2007). Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS. Proc. Natl. Acad. Sci. 104(10): 3847-52. Medline abstract: 17360441

Zhou, Q., Choi, G. and Anderson, D. J. (2001). The bHLH transcription factor Olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2 Neuron 31: 791-807. 11567617

Zhao, Y., Flandin, P., Vogt, D., Blood, A., Hermesz, E., Westphal, H. and Rubenstein, J. L. (2014). Ldb1 is essential for development of Nkx2.1 lineage derived GABAergic and cholinergic neurons in the telencephalon. Dev Biol 385: 94-106. PubMed ID: 24157949

ventral nervous system defective: Biological Overview | Evolutionary Homologs | Regulation | Developmental Biology | Effects of Mutation

date revised: 30 October 2015

Home page: The Interactive Fly © 1997 Thomas B. Brody, Ph.D.

The Interactive Fly resides on the
Society for Developmental Biology's Web server.