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SDB
58th ANNUAL METTING University of Virginia, Charlottesville, VA, June 13-18, 1999 |
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Program Committee: Kathryn Anderson, Marnie Halpern, Nipam
Patel, and Daphne Preuss
Local Organizing Committee: Claire Cronmiller, Ann Sutherland, and Ida Chow |
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| PROGRAM | |||
| SUNDAY, JUNE 13 | |||
| 12:00-7:00 pm | Registration | ||
| Education Symposium (Sponsored by Carl Zeiss) 2:00-4:30 pm | |||
| Susan Singer, Chair | |||
| 2:00 pm | Bruce Alberts (NAS) |
Science, Society and the University: The many challenges ahead | |
| 2:50 pm | Richard Nuccitelli (UC Davis) |
Improving Science Education | |
| 3:00 pm | Poster
presentations on new approaches to science education Please note that these posters will be presented again in Poster Session II, June 15 |
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| 5:45-7:15 pm | Dinner | ||
| President's
Symposium, Morphogenesis and Cell Fate,
7:30-9:00pm In Honor of the 60th Anniversary of the Society for Developmental Biology |
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| Kathryn Anderson, Chair | |||
| 7:30 pm | Kathryn Anderson (Sloan-Kettering Inst.) |
Introduction | |
| 7:40 pm | Ray Keller (U Virginia) |
The convergence code: neural and mesodermal cell strategies for shaping the embryo | |
| 8:20 pm | Chuck Kimmel (U Oregon) |
Patterning dorsal mesodermal development in the zebrafish | |
| 9:00 pm on | Opening Reception | ||
| MONDAY, JUNE 14 | |||
| 8:00-9:00 am | Funding Opportunities
in Developmental Biology Presentations by representatives of federal and private funding agencies: NIH, NSF, ACS and others |
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| Concurrent
Symposia 1-3, 9:00 am-12:00 pm Six 20 minute talks, each with 5 minutes for questions, with a 30 minute break |
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| Symposium 1, Wiring the Nervous System | |||
| Haig Keshishian, Chair | |||
| 9:00 am | Barry Condron (U Virgina) |
Role of midline signaling in the regulation of serotonergic neuron differentiation in the developing insect CNS | |
| 9:25 am | Anne Goriely (Oxford U) |
Regulation and role of the C-Irx genes, two chick homologues of the fly Iroquois genes in the formation of the early nervous system | |
| 9:50 am | Jonathan Eggenschwiler (Sloan-Kettering Inst.) |
The mouse open brain gene is essential for dorsoventral patterning of the neural tube | |
| 10:15 am | Break | ||
| 10:45 am | Haig Keshishian (Yale U) |
Mechanisms governing pupal neuromuscular development in Drosophila | |
| 11:10 am | Yishi Jin (UC Santa Cruz) |
Synaptogenesis and synaptic remodeling in C. elegans | |
| 11:35 am | David Feldheim (Harvard U Med. Sch.) |
Ephrins are required for topographic mapping of visual projections in mammals | |
| Symposium 2, Metamorphosis and Regeneration | |||
| Don Brown, Chair | |||
| 9:00 am | Don Brown (Carnegie Inst. of Washington) |
Amphibian metamorphosis | |
| 9:25 am | Elizabeth Callery (U Toronto) |
Thyroid hormone signalling and metamorphic remodelling in the direct developing frog, Eleutherodacylus coqui | |
| 9:50 am | Jim Truman (U Washington) |
Diversification of endocrine response patterns in the control of metamorphosis | |
| 10:15 am | Break | ||
| 10:45 am | Carl Thummel (U Utah) |
Regulation of Drosophila metamorphosis by the steroid hormone ecdysone | |
| 11:10 am | Bill Bates (Bamfield Marine Station) |
Expression of FGF and distal-less during the outgrowth of ascidian ampullae | |
| 11:35 am | Alejandro Sanchez Alvarado (Carnegie Inst. of Washington) | Amphibian tadpoles and planarians: Model systems for the molecular study of metazoan regeneration | |
| Symposium 3, The Cell Biology of Development | |||
| Judy White, Chair | |||
| 9:00 am | Rick Fehon (U North Carolina) |
Pattern, proliferation, and the apical membrane domain | |
| 9:25 am | Daphne Preuss (U Chicago) |
Pollination in Arabidopsis: Cell adhesion and pollen tube development | |
| 9:50 am | Judy White (U Virginia) |
ADAMs and integrins: evidence that different states of an integrin mediate cell-cell (ADAM) and cell-matrix interactions | |
| 10:15 am | Break | ||
| 10:45 am | Martina Brueckner (Yale U) |
The motor domain of left-right dynein is essential for the development of left-right asymmetry in the mouse | |
| 11:10 am | Erin Newman-Smith (UC Santa Barbara) |
Evidence for the involvement of END-2, a member of the steroid hormone receptor family, in endoderm and mesoderm formation in C. elegans | |
| 11:35 am | Richard Gomer (Rice U) |
A secreted factor regulating aggregate size in Dictyostelium | |
| 12:30-1:30 pm | Lunch | ||
| 1:30-4:00 pm | Poster
Session I Development and Evolution, Gene Expression, Intercellular Communication, Metamorphosis |
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| Workshop 1, Legislation 101 for Scientists, 4:00-5:30 pm | |||
| 4:00 pm | Michael Stephens (Von Scoyoc Assoc. and FASEB) |
Federal funding budget - Understanding the black box | |
| 5:00 pm | Update on human stem cell research | ||
| 5:30-7:00 pm | Dinner | ||
| Plenary
Session 1, Birth Defects and Animal Models Six 20 min talks, each with 5 min for questions, one 15 min break |
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| Chris Wylie, Chair | |||
| 7:30 pm | Andy Copp (UC London) |
Neural tube defects | |
| 7:55 pm | Maximilian Muenke (NIH) |
Holoprosencephaly as a model to study normal and abnormal brain development | |
| 8:20 pm | Angela Christiano (Columbia) |
Skin and hair diseases of humans and mice | |
| 8:45 pm | Break | ||
| 9:00 pm | Ethylin Jabs (Hopkins) |
Human craniofacial development and disorders | |
| 9:25 pm | Eric Olson (U Texas) |
Transcriptional Control of Cardiac Development | |
| 9:50 pm | Richard Harvey (Australia) |
Role of homeodomain factor Nkx2-5 in cardiac development and disease | |
| 10:15-11:30 pm | Poster Session I (cont.) | ||
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TUESDAY, JUNE 15
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| 9:00 am-12:00 | Concurrent
Symposia 4-6 Six 20 minute talks, each with 5 minutes for questions, with a 30 minute break |
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| Symposium 4, Genetics and Genomics | |||
| Philip Benfey, Chair | |||
| 9:00 am | Howard Sirotkin (Skirball) |
Genetic interaction of the homeobox gene bozozok with nodal-related genes in zebrafish development | |
| 9:25 am | William Smith (UC Santa Barbara) |
ENU-induced mutations affecting tail and notochord morphogenesis in the ascidian Ciona savignyi | |
| 9:50 am | Phil Benfey (New York U) |
Radial pattern formation in plants | |
| 10:15 am | Break | ||
| 10:45 am | Susie Zoltewicz (Duke U) |
The oto mutation disrupts development of the forebrain and first pharyngeal arch | |
| 11:10 am | Bill Skarnes (UC Berkeley) |
A resource of mouse mutations in secreted and membrane proteins | |
| 11:35 am | Stacie Loftus (NIH) |
Informatic selection of a neural crest-melanocyte cDNA set for microarray analysis | |
| Symposium 5, Signals That Subdivide | |||
| Chris Wright, Chair | |||
| 9:00 am | Raphael Kopan (Washington U) |
The role of Presenilin in Notch signaling | |
| 9:25 am | Tom Gridley (Jackson Lab) |
Notch signaling in mice | |
| 9:50 am | David Kimelman (U Washington) |
Regulation of dorsal axis formation in Xenopus by a novel GSK-3 binding protein | |
| 10:15 am | Break | ||
| 10:45 am | Gerald Thomsen (NYSU Stony Brook) |
Ubiquitination regulates BMP signaling and embryonic pattern formation in Xenopus | |
| 11:10 am | Jan Christian (Oregon Health Sci) |
A novel cleavage site within the prodomain of the BMP-4 precursor regulates the activity and signaling range of mature BMP-4 | |
| 11:35 am | Chris Wright (Vanderbilt) |
Antagonistic signaling in left-right asymmetry | |
| Symposium 6, Cell Lineage and Cell Polarity | |||
| Mark Martindale, Chair | |||
| 9:00 am | Bill Theurkauf (U Mass) |
Polarity in the Drosophila oocyte | |
| 9:25 am | Laura Berkowitz (U Indiana) |
mes-1, a gene required for unequal divisions of the germline in early C. elegans embryos, encodes a membrane protein localized to the boundary between the germline and gut cells | |
| 9:50 am | Mark Martindale (U Hawaii) |
The origins of mesoderm. A cell lineage analysis in basal metazoans | |
| 10:15 | Break | ||
| 10:45 am | Connie Lane (U Wisconsin-Madison) |
Rethinking Xenopus patterning: revisions in the fate and axis orientation maps | |
| 11:10 am | Elaine Seaver (UT Austin) |
Autonomous development during segment formation in leech: Evidence contradicting a role for engrailed as initiator of a signaling pathway in the segment primordium | |
| 11:35 am | Bridget Lear (U Chicago) |
The roles of intrinsic and extrinsic factors in asymmetric division in the Drosophila central nervous system | |
| 12:30-1:30 pm | Lunch | ||
| 1:30-4:00 pm | Poster
Session II Education, Organogensis, Cell Lineage, Gametogenesis and Fertilization, Signalling Pathways |
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| Workshop 2, Imaging Techniques, 4:00-5:30 pm | |||
| 4:00 pm | Bradley Smith (Duke U) |
Magnetic resonance microscopy for developmental biology | |
| 4:30 pm | Dan Turnbull (Skirball) |
In utero ultrasound microscopy of mouse embryos | |
| 5:00 pm | Robert Thompson (Med. Univ. S. Carolina) |
Confocal microscopy for developmental biology | |
| 5:30-7:00 pm | Dinner | ||
| Plenary Session
2, Gametogenesis and Germ line Development, 7:30-10:15
pm Six 20 min talks, each with 5 min for questions, one 15 min break |
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| Daphne Preuss, Chair | |||
| 7:30 pm | Chris Wylie (U Minnesota) |
Formation and properties of early germ line cells in vertebrates | |
| 7:55 pm | Shirley Tilghman (Princeton) |
The mechanism of genomic imprinting in mammals | |
| 8:20 pm | Tim Bestor (Columbia) |
Gene silencing in mammalian gametogenesis | |
| 8:45 pm | Break | ||
| 9:00 pm | Geraldine Seydoux (Hopkins) |
Control of germ cell fate in embryogenesis | |
| 9:25 pm | Mark Van Doren (Skirball Inst.) |
Germ cell migration and gonad morphogenesis in Drosophila | |
| Steve DiNardo (U Penn) |
Regulating stem cell fate and proliferation in the Drosophila male germline | ||
| 10:15-11:30 pm | Poster Session II (cont.) | ||
| Top of page | |||
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WEDNESDAY, June 16
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| Concurrent
Symposia 7-9, 9:00 am-12:00 pm Six 20 min talks, each with 5 min for questions, and a 30 min break |
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| Symposium 7, Organogenesis | |||
| Rob Martienssen, Chair | |||
| 9:00 am | Rob Martienssen (Cold Spring Harbor) |
Organogenesis in higher plants | |
| 9:25 am | Steve Clark (U Michigan) |
A receptor complex regulating organ formation | |
| 9:50 am | Mary Baylies (Sloan-Kettering Inst.) |
The role of Twist in muscle development in Drosophila and vertebrates | |
| 10:15 am | Break | ||
| 10:45 am | Rob Grainger (U Virginia) |
Early determination events during vertebrate eye development | |
| 11:10 am | Jessica Treisman (Skirball) |
The genetic control of early eye development in Drosophila | |
| 11:35 am | Shankar Srinivas (Columbia U) |
Expression of green fluorescent protein in the ureteric bud of transgenic mice: a new tool for the analysis of ureteric bud morphogenesis | |
| Symposium 8, Signals that Organize the Body Plan | |||
| Mary Mullins, Chair | |||
| 9:00 am | Mary Mullins (U Pennsylvania) |
Genetic analysis of BMP signaling in dorsoventral patterning of the zebrafish embryo | |
| 9:25 am | David Koos (Princeton U) |
The nieuwkoid/dharma/bozozok repressor is required for the specification of the zebrafish gastrula organizer | |
| 9:50 am | Didier Stainier (UC San Francisco) |
Molecular and genetic analysis of endoderm formation in zebrafish | |
| 10:15 am | Break | ||
| 10:45 am | John Klingensmith (Duke U) |
The Spemann's organizer neural inducers Chordin and Noggin are required for anterior development in the mouse | |
| 11:10 am | Joshua Brickman (NIMR-Hill Mill) |
Anterior pattern and targets of the transcription factor Hex | |
| 11:35 am | Michael Shen (Rutgers U) |
The EGF-CFC gene family and mammalian axis determination | |
| Symposium 9, Morphogenesis | |||
| Judith Austin, Chair | |||
| 9:00 am | Judith Austin (U Chicago) |
Regulation of cell shape by the actin cytoskeleton during C. elegans morphogenesis | |
| 9:25 am | Diane Shakes (Coll. William & Mary) |
Anucleate C. elegans sperm can crawl, fertilize oocytes, and direct anterior-posterior polarization of the 1-cell embryo | |
| 9:50 am | Graham Thomas (Penn State U) |
Apical spectrin in epithelia is required for morphogenesis but not apico/basal polarity | |
| 10:15 am | Break | ||
| 10:45 am | Gary Schoenwolf (U Utah) |
Early patterning events in avian embryogenesis | |
| 11:10 am | Shannon Fisher (Carnegie Inst. of Washington) |
Patterning the zebrafish adult skeleton requires chordin function | |
| 11:35 am | Steve Johnson (Washington U) |
Dissecting Kit dependent morphogenesis with conditional mutations in zebrafish | |
| 12:30-1:30 pm | Lunch | ||
| 1:30-4:00 pm | Poster
Session III Patterning, Body Plan, Morphogensis, Animal Models, Medicine and Development, Cell Biology of Development |
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| Workshop 3, Ethics and Technology, 4:00-5:30 pm | |||
| 4:00 pm | Scott Gilbert (Swarthmore) |
Introduction | |
| 4:15 pm | Marie A. Di Beraradino (MCP Hahnemann) |
Cloning and stem cells | |
| 4:40 pm | Stuart Newman (NY Med Coll) |
Forces driving human applications of developmental biology | |
| 5:05 pm | Stephen Jones (State U Washington) |
Billion dollar breakfast: Hungry? | |
| 5:30-7:00 pm | Dinner | ||
| Plenary
Session 3, Evolution of the Body Plan, 7:30-10:15 pm Six 20 min talks, each with 5 min for questions, one 15 min break |
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| Nipam Patel, Chair | |||
| 7:30 pm | Nipam Patel (U. Chicago) |
Evolution of arthropod body patterning | |
| 7:55 pm | Diethard Tautz (Munich) |
Evolution of insect segmentation | |
| 8:20 pm | Bob Goldstein (UNC) |
Evolution of axis specification in nematodes | |
| 8:45 pm | Break | ||
| 9:00 pm | Andy Cameron (California Inst of Technology) |
Genetic regulatory mechanisms and the origin of bilaterian body plans | |
| 9:25 pm | Robert Knight (U of Reading) |
Krox genes and hindbrain evolution | |
| 9:50 pm | Annie Burke (UNC) |
Hox genes and the evolution of the vertebrate axial skeleton | |
| 10:15-11:30 pm | Poster Session III (cont.) | ||
| Top of page | |||
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THURSDAY, JUNE 17
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| 9:00 am-12:00 |
Poster Session IV |
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| 12:30-1:30 pm | Lunch | ||
| The
Annual Academic Press Symposium in Developmental Biology - Embryonic Patterning,
2:00-5:00 pm Six 20 minute talks, each with 5 min for questions, one 30 min break |
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| Marnie Halpern, Chair | |||
| 2:00 pm | David Stein (Albert Einstein) |
Glycosaminoglycans and the establishment of Drosophila embryonic dorsal-ventral polarity | |
| 2:25 pm | Janet Heasman (U Minnesota) |
VegT - A maternal determinant of Xenopus tissue | |
| 2:50 pm | Terry Magnuson (Case Western) |
Clonal analysis of cell fate in mutant mouse embryos | |
| 3:15 pm | Break | ||
| 3:45 pm | Siew-Lan Ang (Strasbourg) |
Hnf3? and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity of the mouse embryo | |
| 4:10 pm | Nicole LeDouarin (Paris) |
Avian development | |
| 4:35 pm | Juan Carlos Ispizua-Belmonte (Salk) | Growth and Patterning of the Vertebrate Limb | |
| 5:30-7:00 pm | Conklin
Award Lecture, Dr. Clement Markert, "How did we get there from here? A short history of our Society." |
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| 7:30 pm on | Reception, Banquet, and Awards Ceremony | ||
| FRIDAY, JUNE 18 | |||
| Departure | |||
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ACKNOWLEDGMENTS
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