Notch

EVOLUTIONARY HOMOLOGS

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C. elegans Notch homologs
The Notch - Presenilin connection in C. elegans and mammals
Enzymatic cleavage of Notch
Cis-interactions between Notch and Delta generate mutually exclusive signalling states
Fringe proteins modulate Notch-ligand and interactions to specify signaling states
Transcytosis of the Notch extracellular domain
Numb promotes degradation of Notch intracellular domain
Phosphorylation of Notch by GSK3ß
Attenuation of Notch signalling by the Down-syndrome-associated kinase DYRK1A dependent phosphorylation
Ubiquitination of Notch
O-glucosylation of notch
Contactin acts as a functional ligand of Notch
MAPK regulation of maternal and zygotic Notch transcript stability in early development

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Notch transcriptional activation complex: Interaction of Notch, Rbpj/CBF1 and Mastermind

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p24 proteins and quality control of Notch family protein in C. elegans
Notch signaling in C. elegans
Other invertebrate Notch homologs

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Fish and Frog Notch homologs
Chicken Notch homologs

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Notch and ear development
Notch and tooth development
Notch and eye development
Notch and lung development
Notch and pancreatic development
Notch and kidney development

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Mammalian Notch homologs
Mammalian Notch homologs: Cell surface and cytoplasmic interactions
Mammalian Notch homologs: Effects of mutation
Transcriptional regulation of Notch
Notch and stem cells
Notch and testis development

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Notch, myeloid cells and the immune response
Notch and T cell development
Notch and vascular morphogenesis
Notch pathway and somitogenesis
Notch pathway and notochord development
Notch and myogenesis
Notch and heart morphogenesis
Notch and endodermal differentiation
Notch and spinal cord development
Notch and neural crest
Notch and gliogenesis
Notch and neural development
A Notch pathway - Ras pathway connection

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Nuclear affectors of the Notch pathway
Targets of Notch signaling
Notch and epidermal development and patterning
Notch and neural diversity
Notch, cell cycle and transformation
Notch and developmental disorders

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