Ras oncogene at 85D

REFERENCES (part 3/3)

Sahai, E., Olson, M. F. and Marshall, C. J. (2001). Cross-talk between Ras and Rho signaling pathways in transformation favours proliferation and increased motility. EMBO J. 20: 755-766. 11179220

Salzberg, A., et al. (1993). The Drosophila Ras2 and Rop gene pair: a dual homology with a yeast Ras-like gene and a suppressor of its loss-of-function phenotype. Development 117: 1309-1319. PubMed Citation: 8404533

Sanchez-Garcia, I. and Martin-Zanca, D. (1997). Regulation of Bcl-2 gene expression by BCR-ABL is mediated by Ras. J. Mol. Biol. 267 (2): 225-228. PubMed Citation: 9096220

Santillo, M., et al. (2001). Opposing functions of Ki- and Ha-Ras genes in the regulation of redox signals. Curr. Biol. 11: 614-619. 11369207

Sato, M. and Kornberg, T. B. (2002). FGF is an essential mitogen and chemoattractant for the air sacs of the Drosophila tracheal system. Dev. Cell 3: 195-207. 12194851

Sato, T. and Nakamura, H. (2004). The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway. Development 131: 4275-4285. 15294862

Sawamoto, K., et al. (1998). Argos induces programmed cell death in the developing Drosophila eye by inhibition of the Ras pathway. Cell Death Differ. 5(4): 262-70. PubMed Citation: 10200472

Sawamoto, K., et al. (1999a). The Drosophila Ral GTPase regulates developmental cell shape changes through the Jun NH(2)-terminal kinase pathway. J. Cell Biol. 146(2): 361-372. PubMed Citation: 10427090

Sawamoto, K., et al. (1999b). Ectopic expression of constitutively activated Ral GTPase inhibits cell shape changes during Drosophila eye development. Oncogene 18(11): 1967-74. PubMed Citation: 10208418

Saxton, T. M., et al. (2001). Gene dosage-dependent functions for phosphotyrosine-Grb2 signaling during mammalian tissue morphogenesis. Curr. Biol. 11: 662-670. 11369229

Scheffzek, K., et al. (1997). The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants. Science 277(5324): 333-338. PubMed Citation: 9219684

Shamloula, H. K., et al. (2002). rugose (rg), a Drosophila A kinase anchor protein, is required for retinal pattern formation and interacts genetically with multiple signaling pathways. Genetics 161(2): 693-710. 12072466

Shemer, G., Kishore, R. and Podbilewicz, B. (2000). Ring formation drives invagination of the vulva in Caenorhabditis elegans: Ras, cell fusion, and cell migration determine structural fates. Dev. Bio. 221: 233-248. PubMed Citation: 10772804

Schlaepfer, D. D. and Hunter, T. (1997). Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src. J. Biol. Chem. 272(20): 13189-13195. PubMed Citation: 9148935

Schlaepfer, D. D., Jones, K. C. and Hunter, T. (1998). Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events. Mol. Cell. Biol. 18(5): 2571-2585. PubMed Citation: 9566877

Schnepp, B., et al. (1996). Vein is a novel component in the Drosophila epidermal growth factor receptor pathway with similarity to the neuregulins. Genes Dev. 10: 2302-13. PubMed Citation: 8824589

Schnorr, J. D. and Berg, C. A. (1996). Differential activity of Ras1 during patterning of the Drosophila dorsoventral axis. Genetics 144 (4): 1545-1557. PubMed Citation: 8978043

Schnorr, J. D., et al. (2001). Ras1 interacts with multiple new signaling and cytoskeletal loci in Drosophila eggshell patterning and morphogenesis. Genetics 159: 609-622. 11606538

Scholz, H., et al. (1997). Control of midline glia development in the embryonic Drosophila. Mech. Dev. 62: 79-91. PubMed Citation: 9106169

Schwarzschild, M. A., et al. (1994). Leukemia inhibitory factor and ciliary neurotrophic factor increase activated Ras in a neuroblastoma cell line and in sympathetic neuron cultures. J. Neurochem. 63: 1246-54. PubMed Citation: 7523587

Sears, R., et al. (2000). Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev. 14: 2501-2514. PubMed Citation: 11018017

Serrano, M., et al. (1995). Inhibition of ras-induced proliferation and cellular transformation by p16INK4. Science 267: 249-252. PubMed Citation: 7809631

Serrano, M., et al. (1997). Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16/INK4a. Cell 88: 593-602. PubMed Citation: 9054499

Shaw, A. C., et al. (1999). Induction of Ig light chain gene rearrangement in heavy chain-deficient B cells by activated Ras. Proc. Natl. Acad. Sci. 96(5): 2239-2243. PubMed Citation: 10051625

Shaw, A. T., et al. (2007). Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis. Genes Dev. 21: 694-707. Medline abstract: 17369402

Shaye, D. S. and Greenwald, I. (2002). Endocytosis-mediated downregulation of LIN-12/Notch upon Ras activation in Caenorhabditis elegans. Nature 420: 686-690. 12478297

Shima, F., et al. (1997). Effect of association with Adenylyl cyclase-associated protein on the interaction of yeast Adenylyl cyclase with Ras protein. Mol. Cell. Biol. 17: 1057-64

Sieburth, D. S., Sun, Q. and Han, M. (1998). SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans. Cell 94(1): 119-130

Sieburth, D. S., et al. (1999). A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval induction. Genes Dev. 13: 2562-2569

Sieglitz, F., Matzat, T., Yuva-Adyemir, Y., Neuert, H., Altenhein, B. and Klambt, C. (2013). Antagonistic feedback loops involving rau and sprouty in the Drosophila eye control neuronal and glial differentiation. Sci Signal 6: ra96. PubMed ID: 24194583

Silver, S. J., Chen, F., Doyon, L., Zink, A. W. and Rebay, I. (2004). New class of Son-of-sevenless (Sos) alleles highlights the complexities of Sos function. Genesis 39: 263-272. 15286999

Silverstein, A. M., et al. (1998). p50(cdc37) binds directly to the catalytic domain of Raf as well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site. J. Biol. Chem. 273(32): 20090-5

Simon, M. A., Dodson, G. S. and Rubin, G. M. (1993). An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro. Cell 73: 169-177

Slack, C., Alic, N., Foley, A., Cabecinha, M., Hoddinott, M.P. and Partridge, L. (2015). The Ras-Erk-ETS-signaling pathway is a drug target for longevity. Cell 162(1):72-83.. PubMed ID: 26119340

Smit, L., van der Horst, G. and Borst, J. (1996). Formation of Shc/Grb2- and Crk adaptor complexes containing tyrosine phosphorylated Cbl upon stimulation of the B-cell antigen receptor. Oncogene 13: 381-389

Sobering, A. K., et al. (2004). Yeast Ras regulates the complex that catalyzes the first step in GPI-anchor biosynthesis at the ER. Cell 117(5): 637-48. 15163411

Solari, F. and Ahringer, J. (2000). NURD-complex genes antagonise Ras-induced vulval development in Caenorhabditis elegans. Curr. Biol. 10(4): 223-6.

Sondermann, H., et al. (2004). Structural analysis of autoinhibition in the Ras activator Son of sevenless. Cell 119(3): 393-405. 15507210

Song, H., et al. (2005). Antagonistic regulation of Yan nuclear export by Mae and Crm1 may increase the stringency of the Ras response. Genes Dev. 19: 1767-1772. 16027171

Stickel, S. and Su, T. T. (2014). Oncogenic mutations produce similar phenotypes in Drosophila tissues of diverse origins. Biol Open 3(3): 201-9. PubMed ID: 24570398

Stokoe, D. and McCormick, F. (1997). Activation of c-Raf-1 by Ras and Src through different mechanisms: activation in vivo and in vitro. EMBO J 16 (9): 2384-2396. PubMed ID: 9171352

Stringham, E., et al. (2002). unc-53 controls longitudinal migration in C. elegans. Development 129: 3367-3379. 12091307

Strutt, H. and Strutt, D. (2003). EGF signaling and ommatidial rotation in the Drosophila eye. Curr. Biol. 13: 1451-1457. 12932331

Suhasini, M., et al. (1998). Cyclic-GMP-dependent protein kinase inhibits the Ras/Mitogen-activated protein kinase pathway. Mol. Cell. Biol. 18(12): 6983-6994.

Suire, S., Hawkins, P. and Stephens, K. (2002). Activation of Phosphoinositide 3-kinasegamma by Ras. Curr. Biol. 12: 1068-1075. 12121613

Sullivan, K. M. C. and Rubin, G. M. (2002). The Ca2+-calmodulin-activated protein phosphatase calcineurin negatively regulates Egf receptor signaling in Drosophila development. Genetics 161: 183-193. 12019233

Sun, H., et al. (2000). Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak. Curr. Biol. 10: 281-284.

Sundaramm, M. and Han, M. (1995). The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction. Cell 83: 889-901

Suzuki, N., et al. (1990). Leucine-rich repeats and carboxyl terminus are required for interaction of yeast adenylate cyclase with RAS proteins. Proc. Natl. Acad. Sci. 87(22): 8711-5

Suzuki, T., et al. (2002). Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation. Genes Dev. 16: 1356-1370. 12050114

Takahashi, F., et al. (1996), Regulation of cell-cell contacts in developing Drosophila eyes by Dsrc41, a new, close relative of vertebrate c-src. Genes Dev. 10(13): 1645-1656

Takuwa, N. and Takuwa, Y. (1997). Ras activity late in G1 phase required for p27kip1 downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts. Mol. Cell. Biol. 17(9): 5348-5358

Tall, G. G., et al. (2001). Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1. Dev. Cell 1: 73-82

Tang, Y., et al. (1997). Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts. Mol. Cell. Biol. 17: 4454-4464

Tang, Y., Yu, J. and Field, J. (1999). Signals from the ras, rac, and rho GTPases converge on the pak protein kinase in rat-1 fibroblasts. Mol. Cell. Biol. 19(3): 1881-91

Tapon, N., et al. (2001). The Drosophila Tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation. Cell 105: 345-355. 11348591

Teleman, A. A., Hietakangas, V., Sayadian, A. C. and Cohen, S. M. (2008). Nutritional control of protein biosynthetic capacity by insulin via Myc in Drosophila. Cell Metab 7: 21-32. PubMed ID: 18177722

Teng, D. H., Engele, C. M. and Venkatesh, T. R. (1991). A product of the prune locus of Drosophila is similar to mammalian GTPase-activating protein. Nature 353(6343): 437-40

Therrien, M., et al. (1995). KSR, a novel protein kinase required for RAS signal transduction. Cell 83: 879-888

Therrien, M., Wong, A. M. and Rubin, G. M. (1998). CNK, a RAF-binding multidomain protein required for RAS signaling. Cell 95(3): 343-53

Therrien, M., et al. (1999). Functional analysis of CNK in RAS signaling. Proc. Natl. Acad. Sci. 96: 13259-13263.

Therrien, M., et al. (2000). A genetic screen for modifiers of a Kinase suppressor of ras-dependent rough eye phenotype in Drosophila. Genetics 156(3): 1231-42. 11063697

Thomas, B. J., et al. (1994). Cell cycle progression in the developing Drosophila eye: roughex encodes a novel protein required for the establishment of G1. Cell 77: 1003-1014

Thomas, S. M., et al. (1992). Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases. Cell 68: 1031-40

Thorson, J. A., et al. (1998). 14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity. Mol. Cell. Biol. 18(9): 5229-38

Tian, X., et al. (2002). PDK1 mediates growth factor-induced Ral-GEF activation by a kinase-independent mechanism. EMBO J. 21: 1327-1338. 11889038

Tong, X.-K., et al. (2000). The endocytic protein intersectin is a major binding partner for the Ras exchange factor mSos1 in rat brain. EMBO J. 19: 1263-1271.

Tong, X. K., et al. (2000). Intersectin can regulate the Ras/MAP kinase pathway independent of its role in endocytosis. J. Biol. Chem. 275(38): 29894-9. 10896662

Tonini, R., et al. (2001). Involvement of CDC25Mm/Ras-GRF1-dependent signaling in the control of neuronal excitability. Mol. Cell. Neurosci. 18: 691-701. 11749043

Tran, J., et al. (2000). Somatic control over the germline stem cell lineage during Drosophila spermatogenesis. Nature 407: 754-757

Trentin, G. A., et al. (2001). A mouse homologue of the Drosophila tumor suppressor l(2)tid gene defines a novel Ras GTPase-activating protein (RasGAP)-binding protein. J. Biol. Chem. 276: 13087-13095. 11116152

Tseng, A. S., et al. (2007). Capicua regulates cell proliferation downstream of the receptor tyrosine kinase/ras signaling pathway. Curr. Biol. 17(8): 728-33. Medline abstract: 17398096

Tzivion, G., Luo, Z. and Avruch, J. (1998). A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity. Nature 394(6688): 88-92

Uberall, F., et al. (1999). Evidence that atypical Protein kinase C-lambda and atypical Protein kinase C-zeta participate in Ras-mediated reorganization of the F-actin cytoskeleton. J. Cell Biol. 144(3): 413-425

Umbhauer, M., et al (1995). Mesoderm induction in Xenopus caused by activation of MAP kinase. Nature 376(6535): 58-62

van der Straten, A., et al. (1997). The heat shock protein 83 (Hsp83) is required for Raf-mediated signalling in Drosophila. EMBO J. 16: 1961-69

von Zelewsky, T., et al. (2000). The C. elegans Mi-2 chromatin-remodelling proteins function in vulval cell fate determination. Development 127: 5277-5284.

Vincent, S., et al. (1998). The Drosophila protein Dof is specifically required for FGF signaling. Molec. Cell 2: 515-525

Vossler, M. R., et al. (1997). cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway. Cell 89(1): 73-82

Wajapeyee, N., Malonia, S. K., Palakurthy, R. K. and Green, M. R. (2013). Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors. Genes Dev 27: 2221-2226. PubMed ID: 24105743

Wakioka, T., et al. (2001), Spred is a Sprouty-related suppressor of Ras signalling. Nature 412: 647-651. 11493923

Walker, J. A., et al. (2006). Reduced growth of Drosophila neurofibromatosis 1 mutants reflects a non-cell-autonomous requirement for GTPase-Activating Protein activity in larval neurons. Genes Dev. 20: 3311-3323. Medline abstract: 17114577

Wan, P. T. C., et al. (2004). Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell 116: 855-867. 15035987

Ward, E. J. and Berg, C. A. (2005). Juxtaposition between two cell types is necessary for dorsal appendage tube formation Mech. Dev. 122: 241-255. 15652711

Wassarman, D. A., Therrien, M. and Rubin, G. M. (1995). The Ras signaling pathway in Drosophila. Curr. Opin. Genet. Dev. 5: 44-50

Wasylyk, C., et al. (1997). Conserved mechanisms of Ras regulation of evolutionary related transcription factors, Ets1 and Pointed P2. Oncogene 14: 899-913

Watari, Y., et al. (1998). Identification of Ce-AF-6, a novel Caenorhabditis elegans protein, as a putative Ras effector. Gene 224(1-2): 53-8

Webb, C. P., et al. (1998). Signaling pathways in ras-mediated tumorigenicity and metastasis. Proc. Natl. Acad. Sci. 95(15): 8773-8778

Weber, J. D., et al. (1997a). Ablation of goalpha overrides G1 restriction point control through Ras/ERK/Cyclin D1-CDK activities. J. Biol. Chem. 272(28): 17320-17326

Weber, J. D., et al. (1997b). Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase. Biochem J. 326: 61-8

Wehr, M. C., Holder, M. V., Gailite, I., Saunders, R. E., Maile, T. M., Ciirdaeva, E., Instrell, R., Jiang, M., Howell, M., Rossner, M. J. and Tapon, N. (2013). Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila. Nat Cell Biol 15: 61-71. PubMed ID: 23263283

White, M. A., et al. (1996). A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation. J. Biol. Chem. 271(28): 16439-42

Willecke, M., Toggweiler, J. and Basler, K. (2011). Loss of PI3K blocks cell-cycle progression in a Drosophila tumor model. Oncogene 30(39): 4067-74. PubMed Citation: 21516128

Wilkins, A., et al. (2000). Dictyostelium RasD is required for normal phototaxis, but not differentiation. Genes Dev. 14: 1407-1413

Williams, E. J., et al. (1997). Selective inhibition of growth factor-stimulated mitogenesis by a cell-permeable Grb2-binding peptide. J. Biol. Chem. 272(35): 22349-22354

Winston, J. T., et al. (1996). Regulation of the cell cycle machinery by oncogenic ras. Oncogene 12: 127-134

Wittwer, F., et al. (2001). Lilliputian: an AF4/FMR2-related protein that controls cell identity and cell growth. Development 128(5): 791-800. 11171403

Wolthuis, R. M. F., et al. (1997). Stimulation of gene induction and cell growth by the Ras effector Rlf. EMBO J. 16(22): 6748-6761

Wood, K. W., et al. (1992). ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK. Cell 68: 1041-50.

Woodcock, S. A. and Hughes, D. A. (2005). p120 Ras GTPase-activating protein associates with fibroblast growth factor receptors in Drosophila. Biochem. J. 380(Pt 3): 767-74. 1503031

Wu, Y. and Han, M. (1994). Suppression of activated Let-60 ras protein defines a role of Caenorhabditis elegans Sur-1 MAP kinase in vulval differentiation. Genes Dev. 8: 147-59

Wolthuis, R. M. F., et al. (1997). Stimulation of gene induction and cell growth by the Ras effector Rlf. EMBO J. 16(22): 6748-6761

Wu, M., Pastor-Pareja, J. C. and Xu, T. (2010). Interaction between RasV12 and scribbled clones induces tumour growth and invasion. Nature 463(7280): 545-8. PubMed Citation: 20072127

Wylie, A., Lu, W. J., D'Brot, A., Buszczak, M. and Abrams, J. M. (2014). p53 activity is selectively licensed in the Drosophila stem cell compartment. Elife 3: e01530. PubMed ID: 24618896

Xing, H. R., Lozano, J. and Kolesnick, R. (2000). Epidermal growth factor treatment enhances the kinase activity of kinase suppressor of Ras. J. Biol. Chem. 275(23): 17276-80. 10764733

Xing, H. R. and Kolesnick, R. N. (2001). Kinase suppressor of Ras signals through Thr269 of c-Raf-1. J Biol Chem. 276(13): 9733-41. 11134016

Xu, X. X., et al. (1998). Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2. Oncogene 16(12):1561-1569

Yamamoto, T., et al. (1997). The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells. J. Cell Biol. 139: 785-795

Yamanashi, Y. and Baltimore, D. (1997). Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok. Cell 88 (2): 205-211

Yan, H., Chin, M. L., Horvath, E. A., Kane, E. A. and Pfleger, C. M. (2009). Impairment of ubiquitylation by mutation in Drosophila E1 promotes both cell-autonomous and non-cell-autonomous Ras-ERK activation in vivo. J Cell Sci 122: 1461-1470. PubMed ID: 19366732

Yan, H., Jahanshahi, M., Horvath, E. A., Liu, H. Y. and Pfleger, C. M. (2010). Rabex-5 ubiquitin ligase activity restricts Ras signaling to establish pathway homeostasis in Drosophila. Curr Biol 20: 1378-1382. PubMed ID: 20655224

Yan, J., et al. (1998). Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase. J. Biol. Chem. 273(37): 24052-6

Yan, Z., et al. (1997). Oncogenic c-Ki-ras but not oncogenic c-Ha-ras up-regulates CEA expression and disrupts basolateral polarity in colon epithelial cells. J. Biol. Chem. 272: 27902-27907

Yang, J. J., Kang, J. S. and Krauss, R. S. (1998). Ras signals to the cell cycle machinery via multiple pathways to induce anchorage-independent growth. Mol. Cell. Biol. 18(5): 2586-2595

Yang, L. and Baker, N. E. (2001). Role of the EGFR/Ras/Raf pathway in specification of photoreceptor cells in the Drosophila retina. Development 128: 1183-1191. 11245584

Yang, L. and Baker, N. E. (2003). Cell cycle withdrawal, progression, and cell survival regulation by EGFR and its effectors in the differentiating Drosophila eye. Developmental Cell 4: 359-369. 12636917

Yao, R. and Cooper, G. M. (1995). Regulation of the Ras signaling pathway by GTPase-activating protein in PC12 cells. Oncogene 11: 1607-1614

Ye, B., et al. (2000). GRASP-1: A neuronal RasGEF associated with the AMPA receptor/GRIP complex. Neuron 26: 603-617.

Yochem, J., Sundaram, M. and Han, M. (1997). Ras is required for a limited number of cell fates and not for general proliferation in Caenorhibditis elegans. Mol. Cell. Biol. 17: 2716-22

Yu, W., et al. (1998). Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK. Curr. Biol. 8(1): 56-64

Zecca, M. and Struhl, G. (2002a). Subdivision of the Drosophila wing imaginal disc by EGFR-mediated signaling. Development 129: 1357-1368. 11880345

Zecca, M. and Struhl, G. (2002b). Control of growth and patterning of the Drosophila wing imaginal disc by EGFR-mediated signaling. Development 129: 1369-1376. 11880346

Zhang, Q., Zheng, Q. and Lu, X. (1999). A genetic screen for modifiers of Drosophila Src42A identifies mutations in Egfr, rolled and a novel signaling gene. Genetics 151: 697-711. PubMed Citation: 9927462

Zhang, S., Charest, P. G. and Firtel, R. A. (2008). Spatiotemporal regulation of Ras activity provides directional sensing. Curr. Biol. 18(20): 1587-93. PubMed Citation: 18948008

Zhang, W., et al. (1999). Citron binds to PSD-95 at glutamatergic synapses on inhibitory neurons in the hippocampus. J. Neurosci. 19(1): 96-108. PubMed Citation: 9870942

Zhang, W., Thompson, B. J., Hietakangas, V. and Cohen S. M. (2011). MAPK/ERK signaling regulates insulin sensitivity to control glucose metabolism in Drosophila. PLoS Genet. 7(12): e1002429. PubMed Citation: 22242005

Zhang, X., Spiegelman, N.A., Nelson, O.D., Jing, H. and Lin, H. (2017). SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation. Elife 6. PubMed ID: 28406396

Zhang, Y., et al. (1997). Kinase suppressor of Ras is ceramide-activated protein kinase. Cell 89 (1): 63-72. PubMed Citation: 9094715

Zhao, S., et al. (2001). Patterning the optic neuroepithelium by FGF signaling and Ras activation. Development 128: 5051-5060. 11748141

Zhao, Z., et al. (2010). p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal. Genes Dev. 24(13): 1389-402. PubMed Citation: 20595231

Zhong, J., et al. (2007). Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo. Nat. Neurosci. 10(5): 598-607. PubMed citation: 17396120

Zhong, Y.(1995a). Mediation of PACAP-like neuropeptide transmission by activation of Ras/Raf and cAMP signal transduction pathways in Drosophila. Nature 375: 588-592. PubMed Citation: 7791875

Zhong, Y. and Pena, L.A. (1995b). A novel synaptic transmission mediated by a PACAP-like neuropeptide in Drosophila. Neuron 14: 527-36. PubMed Citation: 7695899

Zhong, Y. (1996). Genetic dissection of signal transduction mechanisms underlying PACAP-like neuropeptide transmission in Drosophila: synergy of cAMP and Ras/Raf pathways. Ann. N. Y. Acad. Sci. 805: 67-79. PubMed Citation: 8993394

Zhu, J., et al. (1998). Senescence of human fibroblasts induced by oncogenic Raf. Genes Dev. 12(19): 2997-3007

Zhu, J. J., et al. (2002). Ras and rap control AMPA receptor trafficking during synaptic plasticity. Cell 110: 443-455. 12202034

Zhu, L. Q., et al. (2007). Activation of glycogen synthase kinase-3 inhibits long-term potentiation with synapse-associated impairments. J. Neurosci. 27: 12211-12220. PubMed Citation: 17989287

Zimmermann, S., et al. (1997). MEK1 mediates a positive feedback on Raf-1 activity independently of Ras and Src. Oncogene 15(13): 1503-1511

Zimmermann, S. and Moelling, K. (1999). Phosphorylation and regulation of Raf by Akt (Protein kinase B). Science 286: 1741-1744

Zou, X., et al. (1997). Induction of c-myc transcription by the v-Abl tyrosine kinase requires Ras, Raf1, and cyclin-dependent kinases. Genes Dev. 11:654-662

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Ras85D: Biological Overview | Evolutionary Homologs | Regulation | Protein Interactions | Effects of Mutation

date revised: 2 January 2016

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