Imaginal Discs: The Genetic and Cellular Logic of Pattern Formation
by Lewis I. Held, Jr.

Alphabetical list of references:

A (1-157) | B (158-585) | C (586-934) | D (935-1129) | E (1130-1179) | F (1180-1336) | G (1337-1661)

H (1662-1957) | I-J (1958-2107) | K (2108-2375) | L (2376-2630) | M (2631-3024) | N (3025-3153) | O (3154-3218)

P (3219-3478) | Q-R (3479-3716) | S (3717-4226) | T (4227-4413) | U-V (4414-4507) | W (4508-4769) | X-Z (4770-4900)

Bibliography - T (4227-4413)

4227. Tabata, T., Eaton, S., and Kornberg, T.B. (1992). The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation. Genes Dev. 6, 2635-2645.

4228. Tabata, T. and Kornberg, T.B. (1994). Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs. Cell 76, 89-102.

4229. Tabata, T., Schwartz, C., Gustavson, E., Ali, Z., and Kornberg, T.B. (1995). Creating a Drosophila wing de novo, the role of engrailed, and the compartment border hypothesis. Development 121, 3359-3369.

4230. Tabin, C.J., Carroll, S.B., and Panganiban, G. (1999). Out on a limb: parallels in vertebrate and invertebrate limb patterning and the origin of appendages. Amer. Zool. 39, 650-663.

4231. Taghert, P.H., Doe, C.Q., and Goodman, C.S. (1984). Cell determination and regulation during development of neuroblasts and neurones in grasshopper embryo. Nature 307, 163-165.

4232. Tago, K.-i., Nakamura, T., Nishita, M., Hyodo, J., Nagai, S.-i., Murata, Y., Adachi, S., Ohwada, S., Morishita, Y., Shibuya, H., and Akiyama, T. (2000). Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein. Genes Dev. 14, 1741-1749.

4233. Taguchi, A., Sawamoto, K., and Okano, H. (2000). Mutations modulating the argos-regulated signaling pathway in Drosophila eye development. Genetics 154, 1639-1648.

4234. Tahirov, T.H., Inoue-Bungo, T., Morii, H., Fujikawa, A., Sasaki, M., Kimura, K., Shiina, M., Sato, K., Kumasaka, T., Yamamoto, M., Ishii, S., and Ogata, K. (2001). Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFb. Cell 104, 755-767.

4235. Takagaki, Y. and Manley, J.L. (1994). A polyadenlyation factor subunit is the human homologue of the Drosophila suppressor of forked protein. Nature 372, 471-474.

4236. Takahashi, K., Matsuo, T., Katsube, T., Ueda, R., and Yamamoto, D. (1998). Direct binding between two PDZ domain proteins Canoe and ZO-1 and their roles in regulation of the Jun N-terminal kinase pathway in Drosophila morphogenesis. Mechs. Dev. 78, 97-111.

4237. Takahisa, M., Togashi, S., Suzuki, T., Kobayashi, M., Murayama, A., Kondo, K., Miyake, T., and Ueda, R. (1996). The Drosophila tamou gene, a component of the activating pathway of extramacrochaetae expression, encodes a protein homologous to mammalian cell-cell junction-associated protein ZO-1. Genes Dev. 10, 1783-1795.

4238. Takano, T.S. (1998). Loss of notum macrochaetae as an interspecific hybrid anomaly between Drosophila melanogaster and D. simulans. Genetics 149, 1435-1450.

4239. Takano-Shimizu, T. (2000). Genetic screens for factors involved in the notum bristle loss of interspecific hybrids between Drosophila melanogaster and D. simulans. Genetics 156, 269-282.

4240. Takei, K., McPherson, P.S., Schmid, S.L., and De Camilli, P. (1995). Tubular membrane invaginations coated by dynamin rings are induced by GTP-gammaS in nerve terminals. Nature 374, 186-190.

4241. Talbert, P.B. and Garber, R.L. (1994). The Drosophila homeotic mutation Nasobemia (AntpNs) and its revertants: an analysis of mutational reversion. Genetics 138, 709-720.

4242. Tamai, K., Semenov, M., Kato, Y., Spokony, R., Liu, C., Katsuyama, Y., Hess, F., Saint-Jeannet, J.-P., and He, X. (2000). LDL-receptor-related proteins in Wnt signal transduction. Nature 407, 530-535.

4243. Tamkun, J.W., Deuring, R., Scott, M.P., Kissinger, M., Pattatucci, A.M., Kaufman, T.C., and Kennison, J.A. (1992). brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2. Cell 68, 561-572.

4244. Tamura, K., Taniguchi, Y., Minoguchi, S., Sakai, T., Tun, T., Furukawa, T., and Honjo, T. (1995). Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-Jkappa/Su(H). Curr. Biol. 5, 1416-1423.

4245. Tan, P.B.O. and Kim, S.K. (1999). Signaling specificity: the RTK/RAS/MAP kinase pathway in metazoans. Trends Genet. 15, 145-149.

4246. Tanaka Hall, T.M., Porter, J.A., Young, K.E., Koonin, E.V., Beachy, P.A., and Leahy, D.J. (1997). Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins. Cell 91, 85-97.

4247. Tanaka-Matakatsu, M. and Thomas, B. (2001). Shattered is a new rough eye mutant which interacts with roughex, string and fizzy-related. Proc. 42nd Ann. Drosophila Res. Conf. Abstracts Vol., a66.

4248. Tanenbaum, S.B., Gorski, S.M., Rusconi, J.C., and Cagan, R.L. (2000). A screen for dominant modifiers of the irreC-rst cell death phenotype in the developing Drosophila retina. Genetics 156, 205-217.

4249. Tang, A.H., Neufeld, T.P., Kwan, E., and Rubin, G.M. (1997). PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism. Cell 90, 459-467.

4250. Tang, A.H., Neufeld, T.P., Rubin, G.M., and Müller, H.-A.J. (2001). Transcriptional regulation of cytoskeletal functions and segmentation by a novel maternal pair-rule gene, lilliputian. Development 128, 801-813.

4251. Tanimoto, H., Itoh, S., ten Dijke, P., and Tabata, T. (2000). Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs. Molec. Cell 5, 59-71.

4252. Tanoue, T., Adachi, M., Moriguchi, T., and Nishida, E. (2000). A conserved docking motif in MAP kinases common to substrates, activators and regulators. Nature Cell Biol. 2, 110-116.

4253. Tanoue, T., Maeda, R., Adachi, M., and Nishida, E. (2001). Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions. EMBO J. 20, 466-479.

4254. Tashiro, S., Michiue, T., Higashijima, S.-i., Zenno, S., Ishimaru, S., Takahashi, F., Orihara, M., Kojima, T., and Saigo, K. (1993). Structure and expression of hedgehog, a Drosophila segment-polarity gene required for cell-cell communication. Gene 124, 183-189.

4255. Tata, F. and Hartley, D.A. (1993). The role of the Enhancer of split complex during cell fate determination in Drosophila. Development 1993 Suppl., 139-148.

4256. Tata, F. and Hartley, D.A. (1995). Inhibition of cell fate in Drosophila by Enhancer of split genes. Mechs. Dev. 51, 305-315.

4257. Taubert, H. and Szabad, J. (1987). Genetic control of cell proliferation in female germ line cells of Drosophila: Mosaic analysis of five discless mutations. Mol. Gen. Genet. 209, 545-551.

4258. Tautz, D. (1996). Selector genes, polymorphisms, and evolution. Science 271, 160-161.

4259. Tautz, D. (2000). Evolution of transcriptional regulation. Curr. Opin. Gen. Dev. 10, 575-579.

4260. Tautz, D. (2000). A genetic uncertainty problem. Trends Genet. 16, 475-477.

4261. Tayler, T.D. and Garrity, P.A. (2001). Regulation of R1-R6 photoreceptor axon targeting. Proc. 42nd Ann. Drosophila Res. Conf. Abstracts Vol., a253.

4262. Taylor, A.M., Nakano, Y., Mohler, J., and Ingham, P.W. (1993). Contrasting distributions of patched and hedgehog proteins in the Drosophila embryo. Mechs. Dev. 42, 89-96.

4263. Taylor, J., Abramova, N., Charlton, J., and Adler, P.N. (1998). Van Gogh: a new Drosophila tissue polarity gene. Genetics 150, 199-210.

4264. Tear, G. (1999). Neuronal guidance: a genetic perspective. Trends Genet. 15, 113-118.

4265. Teleman, A.A. and Cohen, S.M. (2000). Dpp gradient formation in the Drosophila wing imaginal disc. Cell 103, 971-980.

4266. Telford, M.J. and Thomas, R.H. (1998). Of mites and zen: expression studies in a chelicerate arthropod confirm zen is a divergent Hox gene. Dev. Genes Evol. 208, 591-594.

4267. ten Dijke, P., Miyazono, K., and Heldin, C.-H. (1996). Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. Curr. Opin. Cell Biol. 8, 139-145.

4268. Tepass, U., Gruszynski-DeFeo, E., Haag, T.A., Omatyar, L., Török, T., and Hartenstein, V. (1996). shotgun encodes Drosophila E-cadherin and is preferentially required during cell rearrangement in the neurectoderm and other morphogenetically active epithelia. Genes Dev. 10, 672-685.

4269. Tepass, U. and Hartenstein, V. (1995). Neurogenic and proneural genes control cell fate specification in the Drosophila endoderm. Development 121, 393-405.

4270. Tepass, U., Pellikka, M., Tanentzapf, G., Pinto, M., Hong, H., Smith, C., McGlade, J., and Ready, D. (2001). Crumbs, the Drosophila homolog of human CRB1 (retinitis pigmentosa 12/RP12), is required for photoreceptor cell morphogenesis. Proc. 42nd Ann. Drosophila Res. Conf. Abstracts Vol., a45.

4271. Terracol, R. and Lengyel, J.A. (1994). The thick veins gene of Drosophila is required for dorsoventral polarity of the embryo. Genetics 138, 165-178.

4272. Thackeray, J.R., Gaines, P.C.W., Ebert, P., and Carlson, J.R. (1998). small wing encodes a phospholipase C-gamma that acts as a negative regulator of R7 development in Drosophila. Development 125, 5033-5042.

4273. Thaker, H.M. and Kankel, D.R. (1992). Mosaic analysis gives an estimate of the extent of genomic involvement in the development of the visual system in Drosophila melanogaster. Genetics 131, 883-894.

4274. Thanos, D. and Maniatis, T. (1995). Virus induction of human IFNbeta gene expression requires the assembly of an enhanceosome. Cell 83, 1091-1100.

4275. The, I., Bellaiche, Y., and Perrimon, N. (1999). Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan. Molec. Cell 4, 633-639.

4276. The, I. and Perrimon, N. (2000). Morphogen diffusion: the case of the Wingless protein. Nature Cell Biol. 2, E79-E82.

4277. Theisen, H., Haerry, T.E., O'Connor, M.B., and Marsh, J.L. (1996). Developmental territories created by mutual antagonism between Wingless and Decapentaplegic. Development 122, 3939-3948.

4278. Theisen, H., Purcell, J., Bennett, M., Kansagara, D., Syed, A., and Marsh, J.L. (1994). dishevelled is required during wingless signaling to establish both cell polarity and cell identity. Development 120, 347-360.

4279. Theodosiou, N.A., Zhang, S., Wang, W.-Y., and Xu, T. (1998). slimb coordinates wg and dpp expression in the dorsal-ventral and anterior-posterior axes during limb development. Development 125, 3411-3416.

4280. Thérond, P., Alves, G., Limbourg-Bouchon, B., Tricoire, H., Guillemet, E., Brissard-Zahraoui, J., Lamour-Isnard, C., and Busson, D. (1996). Functional domains of Fused, a serine-threonine kinase required for signaling in Drosophila. Genetics 142, 1181-1198.

4281. Therond, P., Busson, D., Guillemet, E., Limbourg-Bouchon, B., Preat, T., Terracol, R., Tricoire, H., and Lamour-Isnard, C. (1993). Molecular organisation and expression pattern of the segment polarity gene fused of Drosophila melanogaster. Mechs. Dev. 44, 65-80.

4282. Thérond, P.P., Bouchon, B.L., Gallet, A., Dussilol, F., Pietri, T., van den Heuvel, M., and Tricoire, H. (1999). Differential requirements of the Fused kinase for Hedgehog signalling in the Drosophila embryo. Development 126, 4039-4051.

4283. Thérond, P.P., Knight, J.D., Kornberg, T.B., and Bishop, J.M. (1996). Phosphorylation of the fused protein kinase in response to signaling from hedgehog. Proc. Natl. Acad. Sci. USA 93, 4224-4228.

4284. Therrien, M., Chang, H.C., Solomon, N.M., Karim, F.D., Wassarman, D.A., and Rubin, G.M. (1995). KSR, a novel protein kinase required for RAS signal transduction. Cell 83, 879-888.

4285. Therrien, M., Michaud, N.R., Rubin, G.M., and Morrison, D.K. (1996). KSR modulates signal propagation within the MAPK cascade. Genes Dev. 10, 2684-2695.

4286. Therrien, M., Morrison, D.K., Wong, A.M., and Rubin, G.M. (2000). A genetic screen for modifiers of a kinase suppressor of Ras-dependent rough eye phenotype in Drosophila. Genetics 156, 1231-1242.

4287. Therrien, M., Wong, A.M., Kwan, E., and Rubin, G.M. (1999). Functional analysis of CNK in RAS signaling. Proc. Natl. Acad. Sci. USA 96, 13259-13263.

4288. Therrien, M., Wong, A.M., and Rubin, G.M. (1998). CNK, a RAF-binding multidomain protein required for RAS signaling. Cell 95, 343-353.

4289. Thieffry, D., Huerta, A.M., Pérez-Rueda, E., and Collado-Vides, J. (1998). From specific gene regulation to genomic networks: a global analysis of transcriptional regulation in Escherichia coli. BioEssays 20, 433-440.

4290. Thisse, C., Perrin-Schmitt, F., Stoetzel, C., and Thisse, B. (1991). Sequence-specific transactivation of the Drosophila twist gene by the dorsal gene product. Cell 65, 1191-1201.

4291. Thomas, B.J., Gunning, D.A., Cho, J., and Zipursky, S.L. (1994). Cell cycle progression in the developing Drosophila eye: roughex encodes a novel protein required for the establishment of G1. Cell 77, 1003-1014.

4292. Thomas, B.J. and Wassarman, D.A. (1999). A fly's eye view of biology. Trends Genet. 15, 184-190.

4293. Thomas, B.J., Zavitz, K.H., Dong, X., Lane, M.E., Weigmann, K., Finley, R.L., Jr., Brent, R., Lehner, C.F., and Zipursky, S.L. (1997). roughex down-regulates G2 cyclins in G1. Genes Dev. 11, 1289-1298.

4294. Thomas, D. and Tyers, M. (2000). Transcriptional regulation: kamikazi activators. Curr. Biol. 10, R341-R343.

4295. Thomas, G.H. (2001). Spectrin: the ghost in the machine. BioEssays 23, 152-160.

4296. Thomas, G.H., Zarnescu, D.C., Juedes, A.E., Bales, M.A., Londergan, A., Korte, C.C., and Kiehart, D.P. (1998). Drosophila bHeavy-spectrin is essential for development and contributes to specific cell fates in the eye. Development 125, 2125-2134.

4297. Thomas, J.B., Crews, S.T., and Goodman, C.S. (1988). Molecular genetics of the single-minded locus: a gene involved in the development of the Drosophila nervous system. Cell 52, 133-141.

4298. Thomas, J.H. (1993). Thinking about genetic redundancy. Trends Genet. 9, 395-399.

4299. Thomas, J.O. and Travers, A.A. (2001). HMG1 and 2, and related "architectural" DNA-binding proteins. Trends Biochem. Sci. 26, 167-174.

4300. Thomas, U., Ebitsch, S., Gorczyca, M., Koh, Y.H., Hough, C.D., Woods, D., Gundelfinger, E.D., and Budnik, V. (2000). Synaptic targeting and localization of Discs-large is a stepwise process controlled by different domains of the protein. Curr. Biol. 10, 1108-1117.

4301. Thomas, U., Jönsson, F., Speicher, S.A., and Knust, E. (1995). Phenotypic and molecular characterization of SerD, a dominant allele of the Drosophila gene Serrate. Genetics 139, 203-213.

4302. Thomas, U., Speicher, S.A., and Knust, E. (1991). The Drosophila gene Serrate encodes an EGF-like transmembrane protein with a complex expression pattern in embryos and wing discs. Development 111, 749-761.

4303. Thompson, A. and Kavaler, J. (2001). The role of Pax2 in glial cell differentiation during Drosophila sense organ development. Proc. 42nd Ann. Drosophila Res. Conf. Abstracts Vol., a262.

4304. Thompson, C.C. and McKnight, S.L. (1992). Anatomy of an enhancer. Trends Genet. 8, 232-236.

4305. Thompson, D.W. (1913). "On Aristotle as a Biologist." Clarendon Pr., Oxford.

4306. Thompson, D.W. (1917). "On Growth and Form." Cambridge Univ. Pr., Cambridge.

4307. Thompson, J.N., Jr. (1974). Studies on the nature and function of polygenic loci in Drosophila. II. The subthreshold wing vein pattern revealed in selection experiments. Heredity 33, 389-401.

4308. Thompson, J.N., Jr., Hellack, J.J., and Kennedy, J.S. (1982). Polygenic analysis of pattern formation in Drosophila: specification of campaniform sensilla positions on the wing. Dev. Genet. 3, 115-128.

4309. Thompson, J.N., Jr., Spivey, W.E., and Duncan, D.K. (1985). Temperature-dependent responses to a developmental gradient in the Drosophila wing. Experientia 41, 1346-1347.

4310. Thor, S., Andersson, S.G.E., Tomlinson, A., and Thomas, J.B. (1999). A LIM-homeodomain combinatorial code for motor-neuron pathway selection. Nature 397, 76-80.

4311. Thummel, C.S. (1996). Flies on steroids--Drosophila metamorphosis and the mechanisms of steriod hormone action. Trends Genet. 12, 306-310.

4312. Thüringer, F., Cohen, S.M., and Bienz, M. (1993). Dissection of an indirect autoregulatory response of a homeotic Drosophila gene. EMBO J. 12, 2419-2430.

4313. Tie, F., Furuyama, T., and Harte, P.J. (1998). The Drosophila Polycomb Group proteins ESC and E(Z) bind directly to each other and co-localize at multiple chromosome sites. Development 125, 3483-3496.

4314. Tie, F., Furuyama, T., Prasad-Sinha, J., Jane, E., and Harte, P. (2001). Purification and characterization of components of the ESC complex. Proc. 42nd Ann. Drosophila Res. Conf. Abstracts Vol., a90.

4315. Tie, F., Furuyama, T., Prasad-Sinha, J., Jane, E., and Harte, P.J. (2001). The Drosophila Polycomb Group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3. Development 128, 275-286.

4316. Tie, F. and Harte, P. (2001). Characterization of ESC self-association and phosphorylation. Proc. 42nd Ann. Drosophila Res. Conf. Abstracts Vol., a98.

4317. Tien, A.-C., Hsei, H.-Y., and Chien, C.-T. (1999). Dynamic expression and cellular localization of the Drosophila 14-3-3e during embryonic development. Mechs. Dev. 81, 209-212.

4318. Tietze, K., Oellers, N., and Knust, E. (1992). Enhancer of splitD, a dominant mutation of Drosophila, and its use in the study of functional domains of a helix-loop-helix protein. Proc. Natl. Acad. Sci. USA 89, 6152-6156.

4319. Tillib, S., Petruk, S., Sedkov, Y., Kuzin, A., Fujioka, M., Goto, T., and Mazo, A. (1999). Trithorax- and Polycomb-group response elements within an Ultrabithorax transcription maintenance unit consist of closely situated but separable sequences. Mol. Cell. Biol. 19, 5189-5202.

4320. Timms, J.F., Swanson, K.D., Marie-Cardine, A., Raab, M., Rudd, C.E., Schraven, B., and Neel, B.G. (1999). SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages. Curr. Biol. 9, 927-930.

4321. Tio, M., Ma, C., and Moses, K. (1994). spitz, a Drosophila homolog of transforming growth factor-alpha, is required in the founding photoreceptor cells of the compound eye facets. Mechs. Dev. 48, 13-23.

4322. Tio, M. and Moses, K. (1997). The Drosophila TGFalpha homolog Spitz acts in photoreceptor recruitment in the developing retina. Development 124, 343-351.

4323. Tio, M., Zavortink, M., Yang, X., and Chia, W. (1999). A functional analysis of inscuteable and its roles during Drosophila asymmetric cell divisions. J. Cell Sci. 112, 1541-1551.

4324. Tiong, S.Y., Girton, J.R., Hayes, P.H., and Russell, M.A. (1977). Effect of regeneration on compartment specificity of the bithorax mutant of Drosophila melanogaster. Nature 268, 435-437.

4325. Tiong, S.Y.K., Nash, D., and Bender, W. (1995). Dorsal wing, a locus that affects dorsoventral wing patterning in Drosophila. Development 121, 1649-1656.

4326. Tiong, S.Y.K. and Russell, M.A. (1986). Effect of the bithorax mutation on determination in duplicating Drosophila imaginal discs. Dev. Biol. 113, 271-281.

4327. Tiong, S.Y.K. and Russell, M.A. (1990). Clonal analysis of segmental and compartmental homoeotic transformations in Polycomb mutants of Drosophila melanogaster. Dev. Biol. 141, 306-318.

4328. Tiong, S.Y.K., Whittle, J.R.S., and Gribbin, M.C. (1987). Chromosomal continuity in the abdominal region of the bithorax complex of Drosophila is not essential for its contribution to metameric identity. Development 101, 135-142.

4329. Tissot, M. and Stocker, R.F. (2000). Metamorphosis in Drosophila and other insects: the fate of neurons throughout the stages. Progr. Neurobiol. 62, 89-111.

4330. Tix, S., Bate, M., and Technau, G.M. (1989). Pre-existing neuronal pathways in the leg imaginal discs of Drosophila. Development 107, 855-862.

4331. Tix, S., Minden, J.S., and Technau, G.M. (1989). Pre-existing neuronal pathways in the developing optic lobes of Drosophila. Development 105, 739-746.

4332. Tjian, R. and Maniatis, T. (1994). Transcriptional activation: a complex puzzle with few easy pieces. Cell 77, 5-8.

4333. Toba, G., Ohsako, T., Miyata, N., Ohtsuka, T., Seong, K.-H., and Aigaki, T. (1999). The gene search system: a method for efficient detection and rapid molecular identification of genes in Drosophila melanogaster. Genetics 151, 725-737.

4334. Tobler, H. (1966). Zellspezifische Determination und Beziehung zwischen Proliferation und Transdetermination in Bein- und Flügelprimordien von Drosophila melanogaster. J. Embryol. Exp. Morph. 16, 609-633.

4335. Tobler, H. (1969). Beeinflussung der Borstendifferenzierung und Musterbildung durch Mitomycin bei Drosophila melanogaster. Experientia 25, 213-214.

4336. Tobler, H. and Huber, S. (1972). Effect of nitrogen mustard (HN-2) on the development of the male foreleg of Drosophila melanogaster. Dros. Info. Serv. 49, 99-100.

4337. Tobler, H. and Maier, V. (1970). Zur Wirkung von Senfgaslösungen auf die Differenzierung des Borstenorganes und auf die Transdeterminationsfrequenz bei Drosophila melanogaster. W. Roux' Arch. 164, 303-312.

4338. Tobler, H., Rothenbuhler, V., and Nothiger, R. (1973). A study of the differentiation of bracts in Drosophila melanogaster using two mutations, H2 and svde. Experientia 29, 370-371.

4339. Toby, G., Law, S.F., and Golemis, E.A. (1998). Vectors to target protein domains to different cellular compartments. BioTechniques 24, 637-640.

4340. Toering, S.J. (2001). Cellular localization of Drosophila Sprouty protein. Proc. 42nd Ann. Drosophila Res. Conf. Abstracts Vol., a165.

4341. Toffoli, T. and Margolus, N. (1987). "Cellular Automata Machines: A New Environment for Modeling." M.I.T. Pr., Cambridge, Mass.

4342. Toh, Y. (1985). Structure of campaniform sensilla on the haltere of Drosophila prepared by cryofixation. J. Ultrastruct. Res. 93, 92-100.

4343. Tokunaga, C. (1961). The differentiation of a secondary sex comb under the influence of the gene engrailed in Drosophila melanogaster. Genetics 46, 157-176.

4344. Tokunaga, C. (1962). Cell lineage and differentiation on the male foreleg of Drosophila melanogaster. Dev. Biol. 4, 489-516.

4345. Tokunaga, C. (1966). Msc: Multiple sex comb. Dros. Info. Serv. 41, 57.

4346. Tokunaga, C. (1978). Genetic mosaic studies of pattern formation in Drosophila melanogaster, with special reference to the prepattern hypothesis. In "Genetic Mosaics and Cell Differentiation", Results and Problems in Cell Differentiation, Vol. 9, (W.J. Gehring, ed.). Springer-Verlag: Berlin, pp. 157-204.

4347. Tokunaga, C. (1982). Curt Stern, 1902-1981, in memoriam. Jpn. J. Genet. 57, 459-466.

4348. Tokunaga, C. and Gerhart, J.C. (1976). The effect of growth and joint formation on bristle pattern in D. melanogaster. J. Exp. Zool. 198, 79-96.

4349. Tokunaga, C. and Stern, C. (1965). The developmental autonomy of extra sex combs in Drosophila melanogaster. Dev. Biol. 11, 50-81.

4350. Tokunaga, C. and Stern, C. (1969). Determination of bristle direction in Drosophila. Dev. Biol. 20, 411-425.

4351. Tolkunova, E.N., Fujioka, M., Kobayashi, M., Deka, D., and Jaynes, J.B. (1998). Two distinct types of repression domain in Engrailed: one interacts with the Groucho corepressor and is preferentially active on integrated target genes. Mol. Cell. Biol. 18, 2804-2814.

4352. Tolwinski, N. S. and Wieschaus, E. (2001). Armadillo nuclear import is regulated by cytoplasmic anchor Axin and nuclear anchor dTCF/Pan. Development 128, 2107-2117.

4353. Tomilin, A., Reményi, A., Lins, K., Bak, H., Leidel, S., Vriend, G., Wilmanns, M., and Schöler, H.R. (2000). Synergism with the coactivator OBF-1 (OCA-B, BOB-1) is mediated by a specific POU dimer configuration. Cell 103, 853-864.

4354. Tomita, K., Ishibashi, M., Nakahara, K., Ang, S.-L., Nakanishi, S., Guillemot, F., and Kageyama, R. (1996). Mammalian hairy and Enhancer of Split homolog 1 regulates differentiation of retinal neurons and is essential for eye morphogenesis. Neuron 16, 723-734.

4355. Tomlinson, A. (1985). The cellular dynamics of pattern formation in the eye of Drosophila. J. Embryol. Exp. Morph. 89, 313-331.

4356. Tomlinson, A. (1988). Cellular interactions in the developing Drosophila eye. Development 104, 183-193.

4357. Tomlinson, A. (1989). An eye to the main chance. Nature 340, 510-511.

4358. Tomlinson, A. (1989). Short-range positional signals in the developing Drosophila eye. Development 1989 Suppl., 59-63.

4359. Tomlinson, A. (1991). sevenless and its bride: a marriage of molecules? Curr. Biol. 1, 132-134.

4360. Tomlinson, A., Bowtell, D.D.L., Hafen, E., and Rubin, G.M. (1987). Localization of the sevenless protein, a putative receptor for positional information, in the eye imaginal disc of Drosophila. Cell 51, 143-150.

4361. Tomlinson, A., Kimmel, B.E., and Rubin, G.M. (1988). rough, a Drosophila homeobox gene required in photoreceptors R2 and R5 for inductive interactions in the developing eye. Cell 55, 771-784.

4362. Tomlinson, A. and Ready, D.F. (1986). Sevenless: a cell-specific homeotic mutation of the Drosophila eye. Science 231, 400-402.

4363. Tomlinson, A. and Ready, D.F. (1987). Cell fate in the Drosophila ommatidium. Dev. Biol. 123, 264-275.

4364. Tomlinson, A. and Ready, D.F. (1987). Neuronal differentiation in the Drosophila ommatidium. Dev. Biol. 120, 366-376.

4365. Tomlinson, A., Strapps, W.R., and Heemskerk, J. (1997). Linking Frizzled and Wnt signaling in Drosophila development. Development 124, 4515-4521.

4366. Tomlinson, A. and Struhl, G. (1999). Decoding vectorial information from a gradient: sequential roles of the receptors Frizzled and Notch in establishing planar polarity in the Drosophila eye. Development 126, 5725-5738.

4367. Tomlinson, A. and Struhl, G. (2001). Delta/Notch and Boss/Sevenless signals act combinatorially to specify the Drosophila R7 photoreceptor. Molec. Cell 7, 487-495.

4368. Tomoyasu, Y., Nakamura, M., and Ueno, N. (1998). Role of Dpp signalling in prepattern formation of the dorsocentral mechanosensory organ in Drosophila melanogaster. Development 125, 4215-4224.

4369. Tomoyasu, Y., Ueno, N., and Nakamura, M. (2000). The Decapentaplegic morphogen gradient regulates the notal wingless expression through induction of pannier and u-shaped in Drosophila. Mechs. Dev. 96, 37-49.

4370. Torres, M. and Sánchez, L. (1991). The sisterless-b function of the Drosophila gene scute is restricted to the stage when the X:A ratio determines the activity of Sex-lethal. Development 113, 715-722.

4371. Torres, R., Firestein, B.L., Dong, H., Staudinger, J., Olson, E.N., Huganir, R.L., Bredt, D.S., Gale, N.W., and Yancopoulos, G.D. (1998). PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands. Neuron 21, 1453-1463.

4372. Torres-Vazquez, J., Park, S., Warrior, R., and Arora, K. (2001). The transcription factor Schnurri plays a dual role in mediating Dpp signaling during embryogenesis. Development 128, 1657-1670.

4373. Torres-Vazquez, J., Warrior, R., and Arora, K. (2000). schnurri is required for dpp-dependent patterning of the Drosophila wing. Dev. Biol. 227, 388-402.

4374. Townsley, F.M. and Bienz, M. (2000). Actin-dependent membrane association of a Drosophila epithelial APC protein and its effect on junctional Armadillo. Curr. Biol. 10, 1339-1348.

4375. Toyoda, H., Kinoshita-Toyoda, A., and Selleck, S.B. (2000). Structural analysis of glycosaminoglycans in Drosophila and Caenorhabditis elegans and demonstration that tout-velu, a Drosophila gene related to EXT tumor suppressors, affects heparan sulfate in vivo. J. Biol. Chem. 275 #4, 2269-2275.

4376. Traas, J., Hülskamp, M., Gendreau, E., and Höfte, H. (1998). Endoreduplication and development: rule without dividing? Curr. Opin. Plant Biol. 1, 498-503.

4377. Travers, A. (1999). An engine for nucleosome remodeling. Cell 96, 311-314.

4378. Travers, A.A. (1992). The reprogramming of transcriptional competence. Cell 69, 573-575.

4379. Travis, J. (1993). Cell biologists explore "tiny caves". Science 262, 1208-1209.

4380. Treacy, M.N., Neilson, L.I., Turner, E.E., He, X., and Rosenfeld, M.G. (1992). Twin of I-POU: a two amino acid difference in the I-POU homeodomain distinguishes an activator from an inhibitor of transcription. Cell 68, 491-505.

4381. Treier, M., Bohmann, D., and Mlodzik, M. (1995). JUN cooperates with the ETS domain protein Pointed to induce photoreceptor R7 fate in the Drosophila eye. Cell 83, 753-760.

4382. Treier, M., Seufert, W., and Jentsch, S. (1992). Drosophila UbcD1 encodes a highly conserved ubiquitin-conjugating enzyme involved in selective protein degradation. EMBO J. 11, 367-372.

4383. Treisman, J., Harris, E., and Desplan, C. (1991). The paired box encodes a second DNA-binding domain in the Paired homeo domain protein. Genes Dev. 5, 594-604.

4384. Treisman, J., Harris, E., Wilson, D., and Desplan, C. (1992). The homeodomain: a new face for the helix-turn-helix? BioEssays 14, 145-150.

4385. Treisman, J.E. (1999). A conserved blueprint for the eye? BioEssays 21, 843-850.

4386. Treisman, J.E. (2001). Drosophila homologues of the transcriptional coactivation complex subunits TRAP240 and TRAP230 are required for identical processes in eye-antennal disc development. Development 128, 603-615.

4387. Treisman, J.E. and Heberlein, U. (1998). Eye development in Drosophila: formation of the eye field and control of differentiation. Curr. Top. Dev. Biol. 39, 119-158.

4388. Treisman, J.E., Lai, Z.-C., and Rubin, G.M. (1995). shortsighted acts in the decapentaplegic pathway in Drosophila eye development and has homology to a mouse TGF-beta-responsive gene. Development 121, 2835-2845.

4389. Treisman, J.E., Luk, A., Rubin, G.M., and Heberlein, U. (1997). eyelid antagonizes wingless signaling during Drosophila development and has homology to the Bright family of DNA-binding proteins. Genes Dev. 11, 1949-1962.

4390. Treisman, J.E. and Rubin, G.M. (1995). wingless inhibits morphogenetic furrow movement in the Drosophila eye disc. Development 121, 3519-3527.

4391. Treisman, J.E. and Rubin, G.M. (1996). Targets of glass regulation in the Drosophila eye disc. Mechs. Dev. 56, 17-24.

4392. Treisman, R. (1995). Inside the MADS box. Nature 376, 468-469.

4393. Treisman, R. (1996). Regulation of transcription by MAP kinase cascades. Curr. Opin. Cell Biol. 8, 205-215.

4394. Triezenberg, S.J., Kingsbury, R.C., and McKnight, S.L. (1988). Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression. Genes Dev. 2, 718-729.

4395. Trott, R.L., Kalive, M., Paroush, Z., and Bidwai, A.P. (2001). Drosophila melanogaster casein kinase II interacts with and phosphorylates the basic helix-loop-helix proteins m5, m7, and m8 derived from the Enhancer of split Complex. J. Biol. Chem. 276 #3, 2159-2167.

4396. Trowbridge, I.S. (1993). Dynamin, SH3 domains and endocytosis. Curr. Biol. 3, 773-775.

4397. True, J.R., Edwards, K.A., Yamamoto, D., and Carroll, S.B. (1999). Drosophila wing melanin patterns form by vein-dependent elaboration of enzymatic prepatterns. Curr. Biol. 9, 1382-1391.

4398. Trujillo-Cenóz, O. (1985). The eye: development, structure and neural connections. In "Comprehensive Insect Physiology, Biochemistry, and Pharmacology", Vol. 6 (G.A. Kerkut and L.I. Gilbert, ed.). Pergamon Pr.: Oxford, pp. 171-223.

4399. Tsuda, L., Inoue, Y.H., Yoo, M.-A., Mizuno, M., Hata, M., Lim, Y.-M., Adachi-Yamada, T., Ryo, H., Masamune, Y., and Nishida, Y. (1993). A protein kinase similar to MAP kinase activator acts downstream of the Raf kinase in Drosophila. Cell 72, 407-414.

4400. Tsuda, M., Kamimura, K., Nakato, H., Archer, M., Staatz, W., Fox, B., Humphrey, M., Olson, S., Futch, T., Kaluza, V., Siegfried, E., Stam, L., and Selleck, S.B. (1999). The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila. Nature 400, 276-280.

4401. Tsuji, T., Sato, A., Hiratani, I., Taira, M., Saigo, K., and Kojima, T. (2000). Requirements of Lim1, a Drosophila LIM-homeobox gene, for normal leg and antennal development. Development 127, 4315-4323.

4402. Tsujimura, H. (2001). Neuronal programmed cell death is controlled by cell death genes, hid and reaper, in the reorganization of the CNS during Drosophila metamorphosis. Proc. 42nd Ann. Drosophila Res. Conf. Abstracts Vol., a260.

4403. Tsukazaki, T., Chiang, T.A., Davison, A.F., Attisano, L., and Wrana, J.L. (1998). SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor. Cell 95, 779-791.

4404. Tsuneizumi, K., Nakayama, T., Kamoshida, Y., Kornberg, T.B., Christian, J.L., and Tabata, T. (1997). Daughters against dpp modulates dpp organizing activity in Drosophila wing development. Nature 389, 627-631.

4405. Tsunoda, S., Sierralta, J., Sun, Y., Bodner, R., Suzuki, E., Becker, A., Socolich, M., and Zuker, C.S. (1997). A multivalent PDZ-domain protein assembles signalling complexes in a G-protein-coupled cascade. Nature 388, 243-249.

4406. Tsunoda, S., Sierralta, J., and Zuker, C.S. (1998). Specificity in signaling pathways: assembly into multimolecular signaling complexes. Curr. Opin. Gen. Dev. 8, 419-422.

4407. Tucker, J.B., Milner, M.J., Currie, D.A., Muir, J.W., Forrest, D.A., and Spencer, M.-J. (1986). Centrosomal microtubule-organizing centres and a switch in the control of protofilament number for cell surface-associated microtubules during Drosophila wing morphogenesis. Eur. J. Cell Biol. 41, 279-289.

4408. Tun, T., Hamaguchi, Y., Matsunami, N., Furukawa, T., Honjo, T., and Kawaichi, M. (1994). Recognition sequence of a highly conserved DNA binding protein RBP-Jkappa. Nucleic Acids Res. 22, 965-971.

4409. Turing, A.M. (1937). On computable numbers, with an application to the Entscheidungs problem. Proc. Lond. Math Soc., Ser. 2 42, 230-265.

4410. Turing, A.M. (1952). The chemical basis of morphogenesis. Phil. Trans. Roy. Soc. London, Ser. B 237, 37-72.

4411. Tweedie, S., Ng, H.-H., Barlow, A.L., Turner, B.M., Hendrich, B., and Bird, A. (1999). Vestiges of a DNA methylation system in Drosophila melanogaster? Nature Genet. 23, 389-390.

4412. Tyler, A. (1947). An auto-antibody concept of cell structure, growth and differentiation. Growth 10 (Suppl.), 7-19.

4413. Tyler, J.K. and Kadonaga, J.T. (1999). The "dark side" of chromatin remodeling: repressive effects on transcription. Cell 99, 443-446.

Home page: The Interactive Fly © 1995, 1996 Thomas B. Brody, Ph.D.

The Interactive Fly resides on the
Society for Developmental Biology's Web server.