hedgehog
Haines, N. and van den Heuvel, M. (2000). A directed mutagenesis screen in Drosophila melanogaster reveals new
mutants that influence hedgehog signaling. Genetics 156: 1777-1785. 11102373
Hall, J. M. H. et al. (2003). Disruption of Sonic hedgehog signaling alters growth and patterning of lingual taste papillae. Dev. Bio. 255: 263-277. 12648489
Hall, T. M., et al. (1997). Crystal structure of a Hedgehog autoprocessing domain: homology
between Hedgehog and self-splicing proteins. Cell 91(1): 85-97.
Hammerschmidt, M., Bitgood, M. J. and McMahon, A. P. (1996). Protein kinase A is a common negative regulator of Hedgehog signaling
in the vertebrate embryo. Genes Dev. 10: 647-658
Hammond, K. L., et al. (2003). Hedgehog signalling is required for correct anteroposterior patterning of the zebrafish otic vesicle. Development 130: 1403-1417. 12588855
Han, C., Belenkaya, T. Y., Wang, B. and Lin, X. (2004). Drosophila glypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process. Development 131: 601-611. 14729575
Haraguchi, R., et al. (2007). Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling. Development 134(3): 525-33. Medline abstract: 17202190
Hardcastle, Z., et al. (1998). The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants. Development 125(15): 2803-2811.
Harfe, B. D., Scherz, P. J., Nissim, S., Tian, H., McMahon, A. P. and Tabin, C. J. (2004). Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities. Cell 118(4): 517-28. 15315763
Hatini, V. and DiNardo, S. (2001). Distinct signals generate repeating Striped pattern in the embryonic parasegment. Mol. Cell 7: 151-160. 11172720
Hatini, V., Green, R. B., Lengyel, J. A., Bray, S. J. and Dinardo, S. (2005).
The Drumstick/Lines/Bowl regulatory pathway links antagonistic Hedgehog and Wingless
signaling inputs to epidermal cell differentiation.
Genes Dev. 19(6): 709-18. 15769943
Heberlein, U., et al. (1995). Growth and differentiation in the Drosophila eye
coordinated by hedgehog. Nature 373: 709-711
Hebrok, M., Kim, S. K. and Melton, D. A. (1998). Notochord repression of endodermal Sonic hedgehog permits pancreas development. Genes Dev. 12: 1705-1713.
Hebrok, M., et al. (2000). Regulation of pancreas development by hedgehog signaling. Development 127: 4905-4913
Helms, J. A., et al. (1997). Sonic hedgehog participates in craniofacial
morphogenesis and is down-regulated by teratogenic
doses of retinoic acid. Dev. Biol. 187(1): 25-35.
Herzog, W., et al. (2003). Adenohypophysis formation in the zebrafish and its dependence on Sonic hedgehog. Dev. Bio. 254: 36-49. 12606280
Hilton, M. J., et al. (2005). Ihh controls cartilage development by antagonizing Gli3, but requires additional effectors to regulate osteoblast and vascular development. Development 132(19): 4339-51. 16141219
Hirsinger, E., et al. (1997). Noggin acts downstream of Wnt and Sonic Hedgehog to antagonize
BMP4 in avian somite patterning. Development 124(22): 4605-4614.
Hirsinger, E., et al. (2004). Hedgehog signaling is required for commitment but not initial induction of slow muscle precursors. Dev. Biol. 275: 143-157. 15464578
Hisa, T. et al. Hematopoietic, angiogenic and eye defects in Meis1 mutant animals. EMBO J 23: 450-459. PubMed citation: 14713950
Horabin, J. I., Walthall, S., Vied, C. and Moses, M. (2003). A positive role for Patched in Hedgehog signaling revealed by the intracellular trafficking of Sex-lethal, the Drosophila sex determination master switch. Development 130: 6101-6109. 14597576
Horabin, J. I. (2005). Splitting the Hedgehog signal: sex and patterning in Drosophila. Development 132(21): 4801-10. 16207758
Hutchin, M. E., et al. (2005). Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle. Genes Dev. 19(2): 214-23. 15625189
Hoch, M. and Pankratz, M. J. (1996). Control of gut development by fork head and cell signaling molecules in Drosophila. Mech. Dev. 58: 3-14
Hosono, C., Takaira, K., Matsuda, R. and Saigo, K. (2003). Functional subdivision of trunk visceral mesoderm parasegments in Drosophila is required for gut and trachea development. Development 130: 439-449. 12490551
Hu, D. and Helms, J. A. (1999). The role of Sonic hedgehog in normal and abnormal craniofacial
morphogenesis. Development 126: 4873-4884.
Hu, H., Hilton, M. J., Tu, X., Yu, K., Ornitz, D. M. and Long, F. (2005). Sequential roles of Hedgehog and Wnt signaling in osteoblast development. Development 132(1): 49-60. 15576404
Huang, X., Litingtung, Y. and Chiang, C. (2007). Region-specific requirement for cholesterol modification of sonic hedgehog in patterning the telencephalon and spinal cord. Development 134: 2095-2105. Medline abstract: 17507410
Huang, Z. and Kunes, S. (1996). Hedgehog, transmitted along retinal axons, triggers neurogenesis in the developing visual centers of the Drosophila brain. Cell 86: 411-422
Huang, Z. and Kunes, S. (1998). Signals transmitted along retinal axons in Drosophila: Hedgehog signal
reception and the cell circuitry of lamina cartridge assembly. Development 125: 3753-3764.
Huangfu, D., et al. (2003). Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature 426(6962): 83-7. 14603322
Hummel, T., Schimmelpfeng, K. and Klambt, C. (1999). Commissure formation in the embryonic CNS of Drosophila. Identification of required gene functions. Dev. Biol. 209(2): 381-98.
Hummel, T., Attix, S., Gunning, D. and Zipursky, S. L. (2002). Temporal control of glial cell migration in the Drosophila eye requires gilgamesh, hedgehog, and eye specification genes. Neuron 33: 193-203. 11804568
Hynes, M., et al. (1997). Control of cell pattern in the neural tube by the zinc
finger transcription factor and oncogene Gli-1. Neuron 19(1): 15-26.
i Altaba, A. Ruiz (1998). Combinatorial Gli gene function in floor plate and neuronal inductions by Sonic hedgehog. Development 125(12): 2203-2212.
Incardona, J. P., Gruenberg, J. and Roelink, H. (2002). Sonic hedgehog induces the segregation of Patched and Smoothened in endosomes. Curr. Biol. 12: 983-995. 12123571
Inaki, M., Kojima, T., Uedab R. and Saigo, K. (2002). Requirements of high levels of Hedgehog signaling activity for medial-region cell fate determination in Drosophila legs: identification of pxb, a putative Hedgehog signaling attenuator gene repressed along the anterior-posterior compartment boundary. Mech. Dev. 116: 3-18. 12128201
Ingham, P. W., Taylor, A. M. and Nakano,Y. (1991). Role of the Drosophila patched gene in positional
signalling. Nature 353: 184-7
Ingham, P. W. (1993). Localized hedgehog activity controls spatial limits of
wingless transcription in the Drosophila embryo. Nature 366: 560-2
Ingham, P. W. and Fietz, M. J. (1995). Quantitative effects of hedgehog and decapentaplegic
activity on the patterning of the Drosophila wing. Curr Biol 5: 432-440
Ishibashi, M. and McMahon, A. P. (2002). A sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic primordia in the early mouse embryo. Development 129: 4807-4819. 12361972
Jagla, K., et al. (1997). ladybird, a new component of the cardiogenic pathway in Drosophila required for diversification of heart precursors. Development 124: 3471-3479.
Jagla, T., et al. (1998). ladybird determines cell fate decisions during diversification
of Drosophila somatic muscles. Development 125(18): 3699-3708.
Janody, F. Reischl, J. and Dostatni, N. (2000). Persistence of Hunchback in the terminal region of the Drosophila blastoderm
embryo impairs anterior development. Development 127: 1573-1582
Jarov, A., et al. (2003). A dual role for Sonic hedgehog in regulating adhesion and differentiation of neuroepithelial cells. Dev. Biol. 261: 520-536. 14499657
Jensen, A. M., and Wallace, V. A. (1997). Expression of Sonic hedgehog and its putative
role as a precursor cell mitogen in the developing
mouse retina. Development 124: 363-371
Jeong, J., et al. (2004). Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia. Genes Dev. 18: 937-951. 15107405
Jeong, J. and McMahon, A. P. (2005). Growth and pattern of the mammalian neural tube are governed by partially overlapping feedback activities of the hedgehog antagonists patched 1 and Hhip1. Development 132(1): 143-54. 15576403
Jeong, Y. and Epstein, D. J. (2003). Distinct regulators of Shh transcription in the floor plate and notochord indicate separate origins for these tissues in the mouse node. Development 130: 3891-3902. 12835403
Jhaveri, D., et al. (2000). Sense organ identity in the Drosophila antenna is specified by the
expression of the proneural gene atonal. Mech. Dev. 99: 101-111.
Johnson, R. L., Grenier, J. K. and Scott, M. P. (1995). patched overexpression alters wing disc size and pattern: transcriptional and post-transcriptional effects on hedgehog targets. Development 121: 4161-4170
Jones, C., Reifegerste, R. and Moses, K. (2006). Characterization of Drosophila mini-me, a gene required for cell proliferation and survival. Genetics 173(2): 793-808. 16547096
Joulia, L., Bourbon, H. M. and Cribbs, D. L. (2005). Homeotic proboscipedia function modulates hedgehog-mediated organizer activity to pattern adult Drosophila mouthparts. Dev. Biol. 278(2): 496-510. 15680366
Jung, H. S., et al. (1998). Local inhibitory action of BMPs and their relationships with
activators in feather formation: implications for periodic patterning. Dev. Biol. 196(1): 11-23.
Jung, H. S., Oropeza, V. and Thesleff, I. (1999). Shh, bmp-2, bmp-4 and fgf-8 are associated with initiation and patterning of mouse tongue papillae. Mech. Dev. 81(1-2): 179-82.
Jung, S. H., Evans, C. J., Uemura, C. and Banerjee, U. (2005). The Drosophila lymph gland as a developmental model of hematopoiesis. Development 132: 2521-2533. PubMed citation: 15857916
Kameda, T., et al. (2003). Down-regulation of endodermal Shh is required for gland formation in chicken stomach. Mech. Dev. 120: 801-809. 12915230
Kango-Singh, M., Singh, A. and Sun, Y. H. (2003). Eyeless collaborates with Hedgehog and Decapentaplegic signaling in Drosophila eye induction. Dev. Bio. 256: 48-60. 12654291
Karp, S. J., et al. (2000). Indian Hedgehog coordinates endochondral bone growth and morphogenesis via Parathyroid Hormone related-Protein-dependent and -independent
pathways. Development 127: 543-548.
Karunaratne, A., et al. (2002). GATA proteins identify a novel ventral
interneuron subclass in the developing chick spinal cord. Dev. Bio. 249: 30-43. 12217316
Kato, K., Chihara, T. and Hayashi, S. (2004). Hedgehog and Decapentaplegic instruct polarized growth of cell extensions in the Drosophila trachea. Development 131: 5253-5261. 15456724
Kawahira, H., et al. (2003). Combined activities of hedgehog signaling inhibitors regulate pancreas development. Development 130: 4871-4879. 12917290
Kawakami, T., et al. (2002). Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling. Development 129: 5753-5765. 12421714
Kenney, A. M., Widlund, H. R. and Rowitch, D. H. (2004). Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal
precursors. Development 131: 217-228 . 14660435
Kessaris, N., Jamen, F., Rubin, L. L. and Richardson, W. D. (2004). Cooperation between sonic hedgehog and fibroblast growth factor/MAPK signalling pathways in neocortical precursors. Development 131(6): 1289-98. 14960493
Keys, D. N., et al. (1999). Recruitment of a hedgehog regulatory circuit in butterfly
eyespot evolution. Science 283(5401): 532-4.
King. F. J., et al. (2001). Yb modulates the divisions of both germline and somatic stem cells through piwi- and hh-mediated mechanisms in the Drosophila ovary. Molec. Cell 7: 497-508
Kitamura, K., et al (1997). Expression patterns of Brx1 (Rieg gene), Sonic hedgehog, Nkx2.2,
Dlx1 and Arx during zona limitans intrathalamica and embryonic
ventral lateral geniculate nuclear formation. Mech. Dev. 67(1): 83-96.
Knezevic, V., et al. (1997). Hoxd-12 differentially affects preaxial and postaxial chondrogenic
branches in the limb and regulates Sonic hedgehog in a positive
feedback loop. Development 124(22): 4523-4536.
Koebernick, K., Hollemann, T. and Pieler, T. (2003). A restrictive role for Hedgehog signalling during otic specification in Xenopus. Dev. Biol. 260: 325-338. 12921735
Kohtz, J. D., et al. (1998). Regionalization within the mammalian telencephalon is mediated
by changes in responsiveness to Sonic Hedgehog. Development 125(24): 5079-5089.
Kohtz, J. D., et al. (2001). N-terminal fatty-acylation of sonic hedgehog enhances the induction of rodent ventral forebrain neurons. Development 128: 2351-2363
Kojima, T., et al. (1994).
Induction of a mirror-image duplication of anterior wing structures by localized hedgehog expression in the anterior compartment of Drosophila melanogaster wing imaginal discs. Gene 148: 211-7
Kopp, A., and Duncan, I. (2002). Anteroposterior patterning in adult abdominal
segments of Drosophila. Dev. Bio. 242: 15-30
Kopp, A., Muskavitch, M. A. and Duncan, I. (1997a). The roles of hedgehog and engrailed in patterning adult abdominal
segments of Drosophila. Development 124(19): 3703-3714.
Kopp, A. and Duncan, I. (1997b). Control of cell fate and polarity in the adult abdominal segments of Drosophila by optomotor-blind. Development 124(19): 3715-3726.
Kos, L., Chiang, C. and Mahon, K. A. (1998). Mediolateral patterning of somites: multiple axial signals, including Sonic hedgehog, regulate Nkx-3.1 expression. Mech. Dev. 70(1-2): 25-34
Koziel, L., Wuelling, M., Schneider, S. and Vortkamp, A. (2005). Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation. Development 132(23): 5249-60. 16284117
Krebs, O., et al. (2003). Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud. Development 130: 6037-6047. 14597572
Krishnan, V., et al. (1997). Mediation of Sonic hedgehog-induced expression of COUP-TFII by
a protein phosphatase. Science 278(5345): 1947-1950.
Kruger, M., et al. (2001). Sonic hedgehog is a survival factor for hypaxial muscles during mouse development. Development 128: 743-752. 11171399
Kwon, C., et al. (2004). Opposing inputs by Hedgehog and Brinker define a stripe of hairy expression in the Drosophila leg imaginal disc. Development 131: 2681-2692. 15128656
Laforest, L., et al. (1998). Involvement of the Sonic Hedgehog, patched 1 and bmp2 genes in
patterning of the zebrafish dermal fin rays. Development 125(21): 4175-4184.
Lake, B. B., Ford, R. and Kao, K. R. (2001). Xrel3 is required for head development in Xenopus laevis. Development 128: 263-273. 11124121
Lamm, M. L. G., et al. (2002). Sonic hedgehog activates mesenchymal Gli1
expression during prostate ductal bud formation. Dev. Bio. 249: 349-366. 12221011
Larsen, C. W., Hirst, E., Alexandre, C. and Vincent, J.-P. (2003). Segment boundary formation in Drosophila embryos. Development 130: 5625-5635. 14522878
Lawrence, P. A., Casal, J. and Struhl, G. (1999a). hedgehog and engrailed: pattern formation and polarity in the Drosophila
abdomen. Development 126: 2431-2439.
Lawrence, P. A., Casal, J. and Struhl, G. (1999b). The Hedgehog morphogen and gradients of cell affinity in the abdomen of
Drosophila. Development 126: 2441-2449.
Lawrence, P. A., Casal, J. and Struhl, G. (2002). Towards a model of the organisation of planar polarity and pattern in the Drosophila abdomen.
Development 129: 2749-2760. 12015301
Lawson, N. D., Vogel, A. M. and Weinstein, B. M. (2002). sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation. Dev. Cell 3: 127-136. 12110173
Lee, C. S., et al. (2000). SHH-N upregulates Sfrp2 to mediate its competitive interaction with WNT1
and WNT4 in the somitic mesoderm. Development 127: 109-118.
Lee, J. D., et al. (2001a). An acylatable residue of Hedgehog is differentially
required in Drosophila and mouse limb development. Dev. Biol. 233: 122-136. 11319862
Lee, J. D. and Treisman, J. E. (2001b). Sightless has homology to transmembrane acyltransferases and is required to generate active Hedgehog protein. Cur. Bio. 11: 1147-1152. 11509241
Lee, J., et al. (1997). Gli1 is a target of Sonic hedgehog that induces ventral neural tube
development. Development 124(13): 2537-2552.
Lee, J. D., Amanai, K., Shearn, A. and Treisman, J. E. (2002). The ubiquitin ligase Hyperplastic discs negatively regulates hedgehog and decapentaplegic expression by independent mechanisms. Development 129: 5697-5706. 12421709
Lee, J.J., et al. (1992). Secretion and localized transcription suggest a role in positional signaling of products of the segmentation gene hedgehog. Cell 71: 33-50
Lepage, T., et al. (1995). Signal transduction by cAMP-dependent protein kinase A in Drosophila limb pattening. Nature 373: 711-715
Levine, E. M., et al. (1997). Sonic hedgehog promotes rod photoreceptor differentiation in
mammalian retinal cells in vitro. J. Neurosci. 17(16): 6277-6288.
Lewis, K. E. and Eisen, J. S. (2001). Hedgehog signaling is required for primary motoneuron induction in zebrafish. Development 128: 3485-3495. 11566854
Lewis, P. M., et al. (2001). Cholesterol modification of Sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1. Cell 105: 599-612. 11389830
Li, H., et al. (1997). A single morphogenetic field gives rise to two retina primordia under the influence
of the prechordal plate. Development 124: 603-615
Lin, L., Bu, L., Cai, C. L., Zhang, X. and Evans, S. (2007). Isl1 is upstream of sonic hedgehog in a pathway required for cardiac morphogenesis. Dev. Biol. 295(2): 756-63. Medline abstract: 16687132
Litingtung, Y., et al. (2002). Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity. Nature 418: 979-983. 12198547
Liu, H. X., et al. (2004). Sonic hedgehog exerts distinct, stage-specific effects on tongue and taste papilla development. Dev. Biol. 276(2): 280-300. 15581865
Liu, W., et al. (2002). Sonic Hedgehog regulates otic capsule
chondrogenesis and inner ear development in the mouse embryo. Dev. Bio. 248: 240-250. 12167401
Lobjois, V., et al. (2004). Specific regulation of cyclins D1 and D2 by FGF and Shh signaling coordinates cell cycle progression, patterning, and differentiation during early steps of spinal cord development. Dev. Biol. 273: 195-209. 15328007
Long, F., et al. (2001). Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development 128: 5099-5108. 11748145
Long, F., et al. (2004). Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development 131(6): 1309-18. 14973297
López, S. L., et al. (2003). Notch activates sonic hedgehog and both are involved in the specification of dorsal midline cell-fates in Xenopus. Development 130: 2225-2238. 12668635
Lopez-Martinez, A., et al. (1995). Limb-patterning activity and restricted posterior
localization of the amino-terminal product of Sonic
hedgehog cleavage. Curr Biol 5: 791-796
Lu, H. C., et al. (2001). Evidence for a role of protein kinase C in FGF signal transduction in the developing chick limb bud. Development 128: 2451-2460. 11493562
Lu, Q. R., et al. (2000). Sonic hedgehog-regulated oligodendrocyte lineage genes
encoding bHLH proteins in the mammalian central nervous
system. Neuron 25: 317-329.
Luders, F., et al. (2003). Slalom encodes an adenosine 3'-phosphate 5'-phosphosulfate transporter essential for development in Drosophila.
EMBO J. 22(14): 3635-44. 12853478
Lum, L., Yao, S., Mozer, B., Rovescalli, A., von Kessler, D., Nirenberg, M. and Beachy, P. A. (2003). Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells. Science 299: 2039-2045. 12663920
Lupo, G., et al. (2005). Dorsoventral patterning of the Xenopus eye: a collaboration of Retinoid, Hedgehog and FGF receptor signaling.
Development 132(7): 1737-48.15753216
Ma, Y., et al. (2002). Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of Dispatched. Cell 111: 63-75. 12372301
Machold, R., et al. (2003). Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron 39: 937-950. 12971894
Mandal, L., et al. (2007). A Hedgehog- and Antennapedia-dependent niche maintains Drosophila haematopoietic precursors. Nature 446: 320-324. PubMed citation: 17361183
Manning, L., et al. (2007). Regional morphogenesis in the hypothalamus: A BMP-Tbx2 pathway coordinates fate and proliferation through Shh downregulation. Dev. Cell 11(6): 873-85. Medline abstract: 17141161
Marcelle, C., Ahlgren, S. and Bronner-Fraser, M. (1999). In vivo regulation of somite differentiation and proliferation by Sonic Hedgehog. Dev. Biol. 214(2): 277-87.
Mardon, G., Solomon, N. M. and Rubin, G. M. (1994). dachshund encodes a nuclear protein required for normal eye and
leg development in Drosophila. Development 120 (12): 3473-3486.
Marigo, V. and Tabin, C. J. (1996a). Regulation of Patched by Sonic hedgehog in the developing neural tube. Proc. Natl. Acad. Sci. 93: 9346-51
Marigo, V., et al. (1996b). Biochemical evidence that Patched is the Hedgehog receptor. Nature 384: 176-179
Marigo, V., et al. (1996c). Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development. Dev. Biol. 180: 273-283
Marigo, V., et al. (1996d). Conservation in hedgehog signaling: induction of a
chicken patched homolog by Sonic hedgehog in the
developing limb. Development 122: 1225-1233
Martín, V., et al. (2001). The sterol-sensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking. Curr. Biol. 11: 601-607. 11369205
Martinez-Morales, J. R., et al. (1997). Vitronectin is expressed in the ventral region of the neural tube and promotes the differentiation of motor neurons. Development 124(24): 5139-5147.
Masai, I., et al. (2005). The hedgehog-PKA pathway regulates two distinct steps of the differentiation of retinal ganglion cells: the cell-cycle exit of retinoblasts and their neuronal maturation.
Development 132(7): 1539-53. 15728672
Mathieu, J., et al. (2002). Distinct and cooperative roles for Nodal and Hedgehog signals during hypothalamic development. Development 129: 3055-3065. 12070082
Matsumoto, H., et al. (2002). Indian hedgehog as a progesterone-responsive
factor mediating epithelial-mesenchymal interactions in the mouse uterus.
Dev. Biol. 245: 280-290. 11977981
Matsuzaki, M. and Saigo, K. (1996). hedgehog signaling independent of engrailed
and wingless required for post-S1 neuroblast formation in Drosophila CNS. Development 122, 3567-3575.
Maurange, C. and Paro, R. (2002). A cellular memory module conveys epigenetic inheritance of hedgehog expression during Drosophila wing imaginal disc development. Genes Dev. 20: 2672-2683. 12381666
McClure, K. D. and Schubiger, G. (2005). Developmental analysis and squamous morphogenesis of the peripodial epithelium in Drosophila imaginal discs.
Development 132(22): 5033-42. 16236766
McDonald, J. A. and Doe, C. Q. (1997). Establishing neuroblast-specific gene expression in the Drosophila CNS: huckebein is activated by Wingless and Hedgehog and repressed by Engrailed and Gooseberry. Development 124: 1079-1087
McMahon, J. A., et al. (1998). Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev. 12(10): 1438-1452.
Menuet, A., Alunni, A., Joly, J. S., Jeffery, W. R. and Retaux, S. (2007). Expanded expression of Sonic Hedgehog in Astyanax cavefish: multiple consequences on forebrain development and evolution. Development 134(5): 845-55. Medline abstract: 17251267
Merabet, S., Hombria, J. C., Hu, N., Pradel, J. and Graba, Y. (2005).
Hox-controlled reorganisation of intrasegmental patterning cues underlies
Drosophila posterior spiracle organogenesis.
Development 132(13): 3093-3102. 15930099
Miao, N., et al. (1997). Sonic hedgehog promotes the survival of specific CNS neuron populations and protects these
cells from toxic insult In vitro. J. Neurosci. 17(15): 5891-9.
Milenkovic, L., et al. (1999). Mouse patched1 controls body size determination and limb patterning.
Development 126: 4431-4440.
Mill, P., et al. (2005). Shh controls epithelial proliferation via independent pathways that converge on N-Myc. Dev. Cell 9(2): 293-303. 16054035
Minina, E., et al. (2001). BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation. Development 128: 4523-4534. 11714677
Mistretta, C. M., et al. (2003). Cyclopamine and jervine in embryonic rat tongue cultures demonstrate a role for Shh signaling in taste papilla development and patterning: fungiform papillae double in number and form in novel locations in dorsal lingual epithelium. Dev. Bio. 254: 1-18. 12606278
Mito, T., et al. (2002). Involvement of hedgehog, wingless, and dpp in the initiation of proximodistal axis formation during the regeneration of insect legs, a verification of the modified boundary model. Mech. Dev. 114: 27-35. 12175487
Mohler, J. (1988). Requirements for hedgehog, a segmental polarity gene, in
patterning larval and adult cuticle of Drosophila. Genetics 120: 1061-72
Mohler, J. (1995a). Spatial regulation of segment polarity gene expression in the
anterior terminal region of the Drosophila blastoderm embryo. Mech Dev 50: 151-161
Mohler, J., Mahaffey, J.W., Deutsch, E., and Vani, K. (1995b). Control of Drosophila head segment identity by the bZIP homeotic gene cnc. Development 121: 237-247
Monsoro-Burq, A.-H. and Le Douarin, N. M. (2001). BMP4 plays a key role in left-right patterning in chick embryos by maintaining Sonic hedgehog asymmetry. Molec. Cell 7: 789-799
Moore-Scott, B. A. and Manley, N. R. (2005). Differential expression of Sonic hedgehog along the anterior-posterior axis regulates patterning of pharyngeal pouch endoderm and pharyngeal endoderm-derived organs. Dev. Biol. 278: 323-335. 15680353
Motzny, C. K. and Holmgren, R. (1995). The Drosophila Cubitus interruptus protein and its role in
the Wingless and Hedgehog signal transduction pathways. Mech Dev 52: 137-150
Muller, B. and Basler, K. (2000). The repressor and activator forms of Cubitus interruptus control Hedgehog
target genes through common generic Gli-binding sites. Development 127: 2999-3007.
Muller, F., et al. (1999). Intronic enhancers control expression of zebrafish sonic
hedgehog in floor plate and notochord. Development 126(10): 2103-2116.
Muller, F., et al. (2000). Direct action of the Nodal-related signal Cyclops in induction of sonic
hedgehog in the ventral midline of the CNS. Development 127: 3889-3897
Mullor, J. L., et al. (1997). Hedgehog activity, independent of decapentaplegic, participates in
wing disc patterning. Development 124(6): 1227-1237.
Mullor, J. L. and Guerrero, I. (2000). A gain-of-function mutant of patched dissects
different responses to the Hedgehog gradient. Dev. Bio. 228: 211-224.
Munsterberg, A. E., et al. (1995). Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite. Genes Dev 9: 2911-2922
Murtaugh, L. C., Chyung, J. H. and Lassar, A. B. (1999). Sonic hedgehog promotes somitic chondrogenesis by altering the
cellular response to BMP signaling. Genes Dev. 13(2): 225-237.
Murtaugh, L. C., et al. (2001). The chick transcriptional repressor Nkx3.2 acts downstream of Shh to promote BMP-dependent axial chondrogenesis. Developmental Cell 1: 411-422
Continued: see hedgehog References part 3/3 | back to part 1/3
hedgehog
continued:
Biological Overview
| Evolutionary Homologs
| Regulation
| Targets of Activity
| Protein Interactions
| Developmental Biology
| Effects of Mutation
Home page: The Interactive Fly © 1995, 1996 Thomas B. Brody, Ph.D.
The Interactive Fly resides on the
Society for Developmental Biology's Web server.