achaete

REFERENCES

Acar, M., et al. (2006). Senseless physically interacts with proneural proteins and functions as a transcriptional co-activator. Development 133: 1979-1989. Medline abstract: 16624856

Ahmad, I., Dooley, C. M. and Afiat, S. (1998). Involvement of Mash1 in EGF-mediated regulation of differentiation in the vertebrate retina. Dev. Biol. 194(1): 86-98.

Allende, M.L. and Weinberg, E.S. (1994). the expression pattern of two zebrafish achaete-scute homolog (ash) genes is altered in the embryonic brain of the cyclops mutant. Dev. Biol. 166: 509-530

Ashraf, S. I. and Ip, Y. T. (2001). The Snail protein family regulates neuroblast expression of inscuteable and string, genes involved in asymmetry and cell division in Drosophila. Development 128: 4757-4767. 11731456

Asmar, J., Biryukova, I. and Heitzler, P. (2008). Drosophila dLMO-PA isoform acts as an early activator of achaete/scute proneural expression. Dev. Biol. 316(2): 487-97. PubMed Citation: 18329012

Badenhorst, P., Finch, J. T. and Travers, A. A. (2002). Tramtrack co-operates to prevent inappropriate neural development in Drosophila. Mech. Dev. 117: 87-101. 12204250

Bae, S.-K., et al. (2000). The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation. Development 127: 2933-2943.

Battiste, J., et al. (2007). Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord. Development 134(2): 285-93. Medline abstract: 17166924

Bellefroid, E. J., et al. (1998). Xiro3 encodes a Xenopus homolog of the Drosophila Iroquois genes and functions in neural specification. EMBO J. 17: 191-203

Bertrand, V. and Hobert, O. (2009). Linking asymmetric cell division to the terminal differentiation program of postmitotic neurons in C. elegans. Dev. Cell 16(4): 563-75. PubMed Citation: 19386265

Biryukova, I. and Heitzler, P. (2005). The Drosophila LIM-homeodomain protein Islet antagonizes proneural cell specification in the peripheral nervous system. Dev. Biol. 288: 559-570. 16259974

Borges, M., et al. (1997). An achaete-scute homologue essential for neuroendocrine differentiation in the lung. Nature 386(6627): 852-5

Brennan, K., et al. (1999). The Abruptex mutations of Notch disrupt the establishment of proneural clusters in Drosophila. Dev. Biol. 216(1): 230-42.

Brody, T., Rasband, W., Baler, K., Kuzin, A., Kundu, M. and Odenwald, W. F. (2008). Sequence conservation and combinatorial complexity of Drosophila neural precursor cell enhancers. BMC Genomics 9: 371. PubMed Citation: 18673565

Buescher, M., Hing, F. S. and Chia, W. (2002). Formation of neuroblasts in the embryonic central nervous system of Drosophila melanogaster is controlled by SoxNeuro. Development 129: 4193-4203. 12183372

Cabrera, C.V., Alonso, M.C. and Huikeshoven, H. (1994). Regulation of scute function by extramacrochaete in vitro and in vivo. Development 120: 3595-3603

Cadigan, K. M. and Nusse, R. (1996). wingless signaling in the Drosophila eye and embryonic epidermis. Development 122: 2801-12

Cadigan, K. M., et al. (1998). Wingless repression of Drosophila frizzled 2 expression shapes the wingless morphogen gradient in the wing. Cell 93: 767-777.

Campbell, G. and Tomlinson, A. (1998). The roles of the homeobox genes aristaless and Distal-less in patterning the legs and wings of Drosophila. Development 125(22): 4483-4493

Casarosa, S., Fode, C. and Guillemot, F. (1999). Mash1 regulates neurogenesis in the ventral telencephalon. Development 126(3): 525-534.

Castro, D. S., et al. (2006). Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif. Dev. Cell 11(6): 831-44. Medline abstract: 17141158

Cau, E., et al. (1997). Mash1 activates a cascade of bHLH regulators in olfactory neuron progenitors. Development 124: 1611-1621.

Cau, E., et al. (2000). Hes genes regulate sequential stages of neurogenesis in the olfactory epithelium. Development 127: 2323-2332

Cau, E., Casarosa, S. and Guillemot, F. (2002). Mash1 and Ngn1 control distinct steps of determination and differentiation in the olfactory sensory neuron lineage. Development 129: 1871-1880. 11934853

Cau, E. and Wilson, S. W. (2003). Ash1a and Neurogenin1 function downstream of Floating head to regulate epiphysial neurogenesis. Development 130: 2455-2466. 12702659

Chang, J., et al. (2000). The CNS midline cells coordinate proper cell cycle progression and identity determination of the Drosophila ventral neuroectoderm. Dev. Bio. 227: 307-323.

Chen, H., et al. (1997a). Conservation of the Drosophila lateral inhibition pathway in human lung cancer: a hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression. Proc. Natl. Acad. Sci. 94 (10): 5355-5360

Chen, H., et al. (1997b). Tissue-specific expression of human achaete-scute homologue-1 in neuroendocrine tumors: transcriptional regulation by dual inhibitory regions. Cell Growth Differ, 8(6): 677-86

Cho, J. H., Klein, W. H. and Tsai, M. J. (2007). Compensational regulation of bHLH transcription factors in the postnatal development of BETA2/NeuroD1-null retina. Mech. Dev. 124(7-8): 543-50. PubMed citation: 17629466

Choksi, S. P., et al. (2006). Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cells. Dev. Cell 11(6): 775-89. Medline abstract: 17141154

Couso, J. P., Bishop, S. A., and Martinez Arias, A. (1994). The wingless signalling pathway and the patterning of the wing margin in Drosophila. Development 120: 621-36.

Cui, X. and Doe, C. Q. (1995). The role of the cell cycle and cytokinesis in regulating neuroblast sublineage gene expression in the Drosophila CNS. Development 121: 3233-3243

Culí, J., Martín-Blanco, E. and Modolell, J. (2001). The EGF receptor and N signalling pathways act antagonistically in Drosophila mesothorax bristle patterning. Development 128: 299-308

Doonan, R., Hatzold, J., Raut, S., Conradt, B. and Alfonso, A. (2008). HLH-3 is a C. elegans Achaete/Scute protein required for differentiation of the hermaphrodite-specific motor neurons. Mech. Dev. 125(9-10): 883-93. PubMed Citation: 18586090

Dove, H. and Stollewerk, A. (2003). Comparative analysis of neurogenesis in the myriapod Glomeris marginata (Diplopoda) suggests more similarities to chelicerates than to insects. Development 130: 2161-2171. 12668630

Dubois, L., et al. (1998). XCoe2, a transcription factor of the Col/Olf-1/EBF family involved in the specification of primary neurons in Xenopus. Curr. Biol. 8(4): 199-209.

Dubreuil, V., et al. (2002). The role of Phox2b in synchronizing pan-neuronal and type-specific aspects of neurogenesis. Development 129: 5241-5253. 12399315

Ferreiro, B. (1994). XASH genes promote neurogenesis in Xenopus embryos. Development 120: 3649-55

Frank, C. A., Baum, P. D. and Garriga, G. (2003). HLH-14 is a C. elegans Achaete-Scute protein that promotes neurogenesis through asymmetric cell division. Development 130: 6507-6518. 14627726

Fromental-Ramain, C., Vanolst, L., Delaporte, C. and Ramain, P. (2008). pannier encodes two structurally related isoforms that are differentially expressed during Drosophila development and display distinct functions during thorax patterning. Mech. Dev. 125(1-2): 43-57. PubMed citation: 18042352

Galant, R., et al. (1998). Expression pattern of a butterfly achaete-scute homolog reveals the homology of butterfly wing scales and insect sensory bristles. Curr. Biol. 8(14): 807-813.

Garcia-Alonso, L. VanBerkum, M., Grenningloh, G., Schuster, C. and Goodman, C.S. (1995). Fasciclin II controls proneural gene expression in Drosophila. Proc Natl Acad Sci 92: 10501-10505.

Garcia-Bellido, A. and Santamaria, P. (1978). Developmental analysis of the achaete-scute system of Drosophila melanogaster. Genetics 91: 469-486.

Garcia-Garcia, M. J., et al. (1999). Different contributions of pannier and wingless to the patterning of the dorsal mesothorax of Drosophila. Development 126: 3523-3532.

Giagtzoglou, N., et al. (2003). Two modes of recruitment of E(spl) repressors onto target genes. Development 130: 259-270. 12466194

Giangrande, A. (1995). Proneural genes influence gliogenesis in Drosophila. Development 121: 429-438

Gigliani, F., et al. (1996). Interactions among the bHLH domains of the proteins encoded by the Enhancer of split and achaete-scute gene complexes in Drosophila. Mol. Gen. Genet. 251: 628-634.

Gibert, J. M., Marcellini, S., David, J. R., Schlotterer, C. and Simpson, P. (2005). A major bristle QTL from a selected population of Drosophila uncovers the zinc-finger transcription factor Poils-au-dos, a repressor of achaete-scute. Dev. Biol. 288(1): 194-205. 16216235

Golovnin, A., et al. (1999). The su(Hw) insulator can disrupt enhancer-promoter interactions when located more than 20 kilobases away from the Drosophila achaete-scute complex. Mol. Cell. Biol. 19: 3443-3456.

Gomez-Skarmeta, J. L., et al. (1995). Cis-regulation of achaete and scute: shared enhancer-like elements drive their coexpression in proneural clusters of the imaginal discs. Genes Dev 9: 1869-1882.

Gomez-Skarmeta, J.-L., et al. (1996). araucan and caupolican, two members of the novel iroquois complex, encode homeoproteins that control proneural and vein-forming genes. Cell 85:95-105

Gómez-Skarmeta, J. L., et al. (1998). Xiro, a Xenopus homolog of the Drosophila Iroquois complex genes, controls development at the neural plate. EMBO J. 17: 181-190

Gonzalez-Crespo, S. and Levine, M. (1993). Interactions between dorsal and helix-loop-helix proteins initiate the differentiation of the embryonic mesoderm and neuroectoderm in Drosophila. Genes Dev 7: 1703-13.

Gonzalez-Gaitan, M. and Jackle, H. (1995). Invagination centers within the Drosophila stomatogastric nervous system anlage are positioned by Notch-mediated signaling which is spatially controlled through wingless. Development 121: 2313-2325

Groves, A.K., George, K.M., Tissier-Seta, J.P., Engel, J.D., Brunet, J.F. and Anderson, D.J. (1995). Differential regulation of transcription factor gene expression and phenotypic markers in developing sympathetic neurons. Development 121(3): 887-901

Gurganus, M. C., et al. (1998). Genotype-environment interaction at quantitative trait loci affecting sensory bristle number in Drosophila melanogaster. Genetics 149(4): 1883-1898.

Haenlin, M., Kunisch, M., Kramatschek, B. and Campos-Ortega, J.A. (1994). Genomic regions regulating early embryonic expression of the Drosophila neurogenic gene Delta. Mech. Dev. 47: 99-110.

Hans, S. and Campos-Ortega, J. A. (2002). On the organisation of the regulatory region of the zebrafish deltaD gene. Development 129: 4773-4784. 12361969

Hartenstein, V., Tepass, U. and Gruszynski-deFeo, E. (1996). Proneural and neurogenic genes control specification and morphogenesis of stomatogastric nerve cell precursors in Drosophila Dev. Biol. 173: 213-227

Hatakeyama, J., et al. (2001). Roles of homeobox and bHLH genes in specification of a retinal cell type. Development 128: 1313-1322. 11262232

Heitzler, M., et al. (1996). Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila. Development 122: 161-171

Heitzler, P., Vanolst, L., Biryukova, I. and Ramain, P. (2003). Enhancer-promoter communication mediated by Chip during Pannier-driven proneural patterning is regulated by Osa. Genes Dev. 17: 591-596. 12629041

Henrique, D., et al. (1997). cash4, a novel achaete-scute homolog induced by Hensen's node during generation of the posterior nervous system. Genes Dev. 11:603-615.

Hirsch, M.-R., et al. (1998). Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system. Development 125(4): 599-608.

Hoch, M., Broadie, K., Jackle, H. and Skaer, H. (1994). Sequential fates in a single cell are established by the neurogenic cascade in the Malpighian tubules of Drosophila. Development 120: 3439-3450

Hoch, M. and Jackle, H. (1998). Kruppel acts as a developmental switch gene that mediates Notch signalling-dependent tip cell differentiation in the excretory organs of Drosophila. EMBO J. 17(19): 5766-75.

Hojo, M., et al. (2000). Glial cell fate specification modulated by the bHLH gene Hes5 in mouse retina. Development 127: 2515-2522.

Huang, M.-L., Hsu, C.-H. and Chien, C.-H. (2000). The proneural gene amos promotes multiple dendritic neuron formation in the Drosophila peripheral nervous system. Neuron 25: 57-67

Huber, K., et al. (2002). Development of chromaffin cells depends on MASH1 function. Development 129: 4729-4738. 12361965

Jacobsen, T. L., et al. (1998). Cis-interactions between Delta and Notch modulate neurogenic signalling in Drosophila. Development 125(22): 4531-4540

Jafar-Nejad, H., et al. (2003). Senseless acts as a binary switch during sensory organ precursor selection. Genes Dev. 17: 2966-2978. 14665671

Jafar-Nejad, H., Tien, A. C., Acar, M. and Bellen, H. J. (2006). Senseless and Daughterless confer neuronal identity to epithelial cells in the Drosophila wing margin. Development 133(9): 1683-92. 16554363

Jennings, B. H., Tyler, D. M. and Bray, S. J. (1999). Target specificities of Drosophila Enhancer of split basic helix-loop-helix proteins. Mol. Cell. Biol. 19: 4600-4610.

Jimenez, F. and Campos-Ortega, J.A. (1990). Defective neuroblast commitment in mutants of the achaete-scute complex and adjacent genes of Drosophila melanogaster. Neuron 5:81-89

Johnston, L. A. and Edgar, B. A. (1998). Wingless and Notch regulate cell-cycle arrest in the developing Drosophila wing. Nature 394(6688): 82-84.

Joshi, M., Buchanan, K. T., Shroff, S. and Orenic, T. V. (2006). Delta and Hairy establish a periodic prepattern that positions sensory bristles in Drosophila legs. Dev. Biol. 293(1): 64-76. 16542648

Ju, B. G., et al. (2004). Activating the PARP-1 sensor component of the Groucho/ TLE1 corepressor complex mediates a CaMKinase II-dependent neurogenic gene activation pathway. Cell 119: 815-829. 15607978

Kanekar, S., et al. (1997). Xath5 participates in a network of bHLH genes in the developing Xenopus retina. Neuron 19(5): 981-994.

Kazanjian, A., Wallis, D., Au, N., Nigam, R., Venken, K. J., Cagle, P. T., Dickey, B. F., Bellen, H. J., Gilks, C. B. and Grimes, H. L. (2004). Growth factor independence-1 is expressed in primary human neuroendocrine lung carcinomas and mediates the differentiation of murine pulmonary neuroendocrine cells. Cancer Res. 64: 6874-6882. 15466176

Kehl, B. T., Cho, K.-O. and Choi, K.-W. (1998). mirror, a Drosophila homeobox gene in the iroquois complex, is required for sensory organ and alula formation. Development 125: 1217-1227.

Kim, J., et al. (2002). SOX10 maintains multipotency and inhibits neuronal differentiation of neural crest stem cells. Neuron 38: 17-31. 12691661

Klein, T. and Campos-Ortega, J. A. (1997). klumpfuss, a Drosophila gene encoding a member of the EGR family of transcription factors, is involved in bristle and leg development. Development (16): 3123-3134.

Kondo, T. and Raff, M. (2000). Basic helix-loop-helix proteins and the timing of oligodendrocyte differentiation. Development 127: 2989-2998.

Korzh, V., et al. (1998). Expression of zebrafish bHLH genes ngn1 and nrd defines distinct stages of neural differentiation. Dev. Dyn. 213(1): 92-104.

Kramatschek, B. and Campos-Ortega, J.A. (1994). Neuroecotdermal transcription of the Drosophila neurogenic genes E(spl) and HLH-m5 is regulated by proneural genes. Development 120: 815-826.

Küry, P., et al. (2002). Mammalian Achaete scute homolog 2 is expressed in the adult sciatic nerve and regulates the expression of Krox24, Mob-1, CXCR4, and p57kip2 in Schwann Cells. J. Neurosci. 22(17): 7586-7595. 12196582

Lai, E. C. and Posakony, J. W. (1998). Regulation of Drosophila neurogenesis byRNA:RNA duplexes? Cell 93: 1103-1104

Leviten, M. W., Lai, E. C. and Posakony, J. W. (1997). The Drosophila gene encodes a novel small protein and shares 3' UTR sequence motifs with multiple Enhancer of split Complex genes. Development 124: 4039-4051

Liu, Y., Helms, A. W. and Johnson, J. E. (2004). Distinct activities of Msx1 and Msx3 in dorsal neural tube development. Development 131: 1017-1028. 14973289

Lo, L., Tiveron, M.-C. and Anderson, D. J. (1998). MASH1 activates expression of the paired homeodomain transcription factor Phox2a, and couples pan-neuronal and subtype-specific components of autonomic neuronal identity. Development 125(4): 609-620.

Lin, R., Hill, R. J. and Priess, J. R. (1998). POP-1 and anterior-posterior fate decisions in C. elegans embryos. Cell 92: 229-239. PubMed Citation: 9458047

Ma, Q, Kintner, C. and Anderson, D. J. (1996). Identivication of neurogenin, a vertebrate neuronal determination gene. Cell 87: 43-52

Ma, Q., et al. (1997). Mash1 and neurogenin1 expression patterns define complementary domains of neuroepithelium in the developing CNS and are correlated with regions expressing notch ligands. J. Neurosci. 17: 3644-3652.

Ma, Y., et al. (1998). Gene regulatory functions of Drosophila fish-hook, a high mobility group domain Sox protein. Mech. Dev. 73(2): 169-82. Medline abstract: 9622621

Marcellini, S., Gibert, J.-M. and Simpson, P. (2005). achaete, but not scute, is dispensable for the peripheral nervous system of Drosophila. Dev. Biol. 285: 545-553. PubMed citation: 16084506

Martinez, C. and Modolell, J. (1991). Cross-regulatory interactions between the proneural achaete and scute genes of Drosophila. Science 251: 1485-1487

Matter-Sadzinski, L., et al. (2001). Specification of neurotransmitter receptor identity in developing retina: the chick ATH5 promoter integrates the positive and negative effects of several bHLH proteins. Development 128: 217-231

Meir, E., et al. (2002). Robustness, flexibility, and the role of lateral inhibition in the neurogenic network. Curr. Biol. 12: 778-786. 12015114

Meredith, A and Johnson. J. E. (2000). Negative autoregulation of Mash1 expression in CNS development. Dev. Biol. 222: 336-346

Mizumoto, K. and Sawa, H. (2007). Cortical beta-catenin and APC regulate asymmetric nuclear beta-catenin localization during asymmetric cell division in C. elegans. Dev. Cell 12(2): 287-99. PubMed Citation: 17276345

Mizuseki, K., et al. (1998). Xenopus Zic-related-1 and Sox-2, two factors induced by chordin, have distinct activities in the initiation of neural induction. Development 125(4): 579-587

Nakayama, H., et al. (1997). Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway. Dev. Genet. 21(1): 21-30.

Nègre, N., Ghysen, A. and Martinez, A. M. (2003). Mitotic G2-arrest is required for neural cell fate determination in Drosophila. Mech. Dev. 120: 253-265. 12559497

Nellesen, D. T., Lai, E. C. and Posakony, J. W. (1999). Discrete enhancer elements mediate selective responsiveness of enhancer of split complex genes to common transcriptional activators. Dev. Biol. 213(1): 33-53.

Neumann, C. J. and Cohen, S. M. (1997). Long-range action of Wingless organizes the dorsal-ventral axis of the Drosophila wing. Development 124: 871-880

Nakada, Y., Hunsaker, T. L., Henke, R. M. and Johnson, J. E. (2004). Distinct domains within Mash1 and Math1 are required for function in neuronal differentiation versus neuronal cell-type specification. Development 131(6): 1319-30. 14993186

Nolo, R., Abbott, L. A. and Bellen, H. J. (2000), Senseless, a Zn finger transcription factor, is necessary and sufficient for sensory organ development in Drosophila. Cell. 102(3): 349-62. 10975525

Okamura, Y. and Saga, Y. (2008). Notch signaling is required for the maintenance of enteric neural crest progenitors. Development 135(21): 3555-65. PubMed Citation: 18832397

Oellers, N., Dehio, M., and Knust, E. (1994). bHLH proteins encoded by the Enhancer of split complex of Drosophila negatively interfere with the transcriptional activation mediated by proneural genes. Mol. Gen. Genet. 244: 465-73

Ohsako, S. Hyer, J. Panganiban, G. Oliver, I. and Caudy, M. (1994). Hairy function as a DNA-binding helix-loop-helix repressor of Drosophila sensory organ formation. Genes Dev. 8: 2743-2755.

Orenic, T. W., et al. (1993) The spatial organization of epidermal structures: hairy establishes the geometrical pattern of Drosophila leg bristles by delimiting the domains of achaete expression. Development 118: 9-20

Overton, P. M., Meadows, L. A., Urban, J. and Russell, S. (2002). Evidence for differential and redundant function of the Sox genes Dichaete and SoxN during CNS development in Drosophila. Development 129: 4219-4228. 12183374

Parks, A. L., Huppert, S. S. and Muskavitch, M. A. (1997). The dynamics of neurogenic signalling underlying bristle development in Drosophila melanogaster. Mech. Dev. 63 (1): 61-74.

Parras, C., et al. (1996). Control of neural precursor specification by proneural proteins in the CNS of Drosophila. EMBO J. 15: 6394-99

Parras, C. M., et al. (2002). Divergent functions of the proneural genes Mash1 and Ngn2 in the specification of neuronal subtype identity. Genes Dev. 16: 324-338. 11825874

Pattyn, A., et al. (1999). The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives. Nature 398(6734): 366-70.

Petryniak, M. A., et al. (2007). Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain. Neuron 55: 417-433. Medline abstract: 17678855

Phillips, R. G., Warner, N. L. and Whittle, J. R. (1999). Wingless signaling leads to an asymmetric response to Decapentaplegic-dependent signaling during sense organ patterning on the notum of Drosophila melanogaster. Dev. Biol. 207(1): 150-162.

Pi, H., Huang, S. K., Tang, C. Y., Sun, Y. H. and Chien, C. T. (2004). phyllopod is a target gene of proneural proteins in Drosophila external sensory organ development. Proc. Natl. Acad. Sci. 101: 8378-8383. 15148389

Poitras, L., Ghanem, N., Hatch, G. and Ekker, M. (2007). The proneural determinant MASH1 regulates forebrain Dlx1/2 expression through the I12b intergenic enhancer. Development 134(9): 1755-65. Medline abstract: 17409112

Ramain, P., et al. (2000). Interactions between Chip and the Achaete/Scute-Daughterless heterodimers are required for Pannier-driven proneural patterning. Mol. Cell 6: 781-790

Reeves, N. and Posakony, J. W. (2005). Genetic programs activated by proneural proteins in the developing Drosophila PNS. Dev. Cell 8(3): 413-25. 15737936

Romani, S. Campuzano, S. and Modolell, J. (1987). The achaete-scute complex is expressed in neurogenic regions of Drosophila embryos. EMBO J. 6: 2085-2092

Ross, J. M., Kalis, A. K., Murphy, M. W. and Zarkower, D. (2005). The DM domain protein MAB-3 promotes sex-specific neurogenesis in C. elegans by regulating bHLH proteins. Dev. Cell 8(6): 881-92. 15935777

Rossant, J., et al. (1998). Mash2 is expressed in oogenesis and preimplantation development but is not required for blastocyst formation. Mech. Dev. 73(2): 183-191.

Rulifson, E. J. and Blair, S. S. (1995). Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila. Development 121: 2813-2824

Saito, T., et al. (1996). Identification of novel paired homeodomain protein related to C. elegans unc-4 as a potential downstream target of MASH1. Dev. Biol. 180 (1): 143-155.

Sato, M, et al. (1999). Bar homeobox genes are latitudinal prepattern genes in the developing Drosophila notum whose expression is regulated by the concerted functions of decapentaplegic and wingless. Development 126: 1457-1466.

Schlatter, R. and Maier, D. (2005). The Enhancer of split and Achaete-Scute complexes of Drosophilids derived from simple ur-complexes preserved in mosquito and honeybee. BMC Evol. Biol. 5: 67. 16293187

Seugnet, L., Simpson, P. and Haenlin, M. (1997). Transcriptional regulation of Notch and Delta: requirement for neuroblast segregation in Drosophila. Development 124: 2015-2025.

Shroff, S., Joshi, M. and Orenic, T. V. (2007). Differential Delta expression underlies the diversity of sensory organ patterns among the legs of the Drosophila adult. Mech. Dev. 124: 43-58. Medline abstract: 17107776

Singson, A., Leviten, M.W., Bang, A.G., Hua, X.H. and Posakony, J.W. (1994). Direct downstream targets of proneural activators in the imaginal disc include genes involved in lateral inhibitory signaling. Genes Dev. 8(17): 2058-2071

Skeath, J.B. and Carroll, S.B. (1992a). Regulation of proneural gene expression and cell fate during neuroblast segregation in the Drosophila embryo. Development 114: 939-946

Skeath, J. B., et al. (1992b). Gene regulation in two dimensions: the proneural achaete-scute genes are controlled by combinations of axis-patterning genes through a common intergenic control region. Genes and Dev. 6:2606-19.

Skeath, J.B. Panganiban, G. and Carroll, S.B. (1994). The ventral nervous system defective gene controls proneural gene expression at two distinct steps during neuroblast formation in Drosophila. Development 120: 1517-1524

Skeath, J. B. (1998). The Drosophila EGF receptor controls the formation and specification of neuroblasts along the dorsal-ventral axis of the Drosophila embryo. Development 125(17): 3301-3312.

Sriuranpong, V., et al. (2002). Notch signaling induces rapid degradation of achaete-scute homolog 1. Mol Cell Biol. 22(9): 3129-39. 11940670

Stollewerk, A. (2000). Changes in cell shape in the ventral neuroectoderm of Drosophila melanogaster depend on the activity of the achaete-scute complex genes. Dev. Genes Evol. 210: 190-199

Sudarsan, V., et al. (2002). A genetic hierarchy establishes mitogenic signaling and mitotic competence in the renal tubules of Drosophila. Development 129: 935-944. 11861476

Sugimori, M., et al. (2007). Combinatorial actions of patterning and HLH transcription factors in the spatiotemporal control of neurogenesis and gliogenesis in the developing spinal cord. Development 134(8): 1617-29. Medline abstract: 17344230

Sugimori, M., et al. (2008). Ascl1 is required for oligodendrocyte development in the spinal cord. Development 135: 1271-1281. PubMed Citation: 18287202

Talikka, M., Perez, S. E. and Zimmerman, K. (2002). Distinct patterns of downstream target activation are specified by the helix-loop-helix domain of proneural basic helix-loop-helix transcription factors. Dev. Bio. 247: 137-148. 12074558

Tanaka, M., et al. (1997). Mash2 acts cell autonomously in mouse spongiotrophoblast development. Dev. Biol. 190(1): 55-65.

Tepass, U. and Hartenstein, V. (1995). Neurogenic and proneural genes control cell fate specification in the Drosophila endoderm. Development 121: 393-405

Thellmann, M., Hatzold, J. and Conradt, B. (2003). The Snail-like CES-1 protein of C. elegans can block the expression of the BH3-only cell-death activator gene egl-1 by antagonizing the function of bHLH proteins. Development 130: 4057-4071. 12874127

Tomita, K., et al. (1996). Mash1 promotes neuronal differentiation in the retina. Genes Cells 1 (8): 765-774.

Tomita, K., et al. (2000). Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous system. EMBO J. 19: 5460-5472

Tomoyasu, Y., Nakamura, M. and Ueno, N. (1998). Role of Dpp signalling in prepattern formation of the dorsocentral mechanosensory organ in Drosophila melanogaster. Development 125(21): 4215-4224

Torii, M.-A., et al. (1999). Transcription factors Mash-1 and Prox-1 delineate early steps in differentiation of neural stem cells in the developing central nervous system. Development 126(3): 443-456.

Tsubota, T., Saigo, K. and Kojima, T. (2008). Hox genes regulate the same character by different strategies in each segment. Mech. Dev. 125(9-10): 894-905. PubMed Citation: 18586088

Tulin, A., Stewart, D. and Spradling, A. C. (2002). The Drosophila heterochromatic gene encoding poly(ADP-ribose) polymerase (PARP) is required to modulate chromatin structure during development. Genes Dev. 16(16): 2108-19. 12183365

Tulin, A. and Spradling, A. (2003). Chromatin loosening by poly(ADP)-ribose polymerase (PARP) at Drosophila puff loci. Science 299: 560-562. 12543974

Tuttle, R., et al. (1999). Defects in thalamocortical axon pathfinding correlate with altered cell domains in Mash-1-deficient mice. Development 126(9): 1903-1916.

van der Flier, L. G., et al. (2009). Transcription factor Achaete Scute-Like 2 controls intestinal stem cell fate. Cell 136: 903-912. PubMed Citation: 19269367

van Doren, M., Ellis, H.M. and Posakony, J.W. (1991). The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete-scute protein complexes. Development 113: 245--255

van Doren, M., Bailey, A.M., Esnayra, J., Ede, K. and Posakony, J.W. (1994). Negative regulation of proneural gene activity: hairy is a direct transcriptional repressor of achaete. Genes Dev. 8(22): 2729-42.

Von Ohlen, T., Syu, L. J. and Mellerick, D. M. (2007). Conserved properties of the Drosophila homeodomain protein, Ind. Mech. Dev. 124(11-12): 925-3417900877

Verma-Kurvari, S., et al. (1996). Lineage-specific regulation of the neural differentiatiion gene MASH1. Dev. Biol. 180: 605-617

Verma-Kurvari, S., et al. (1998). Multiple elements regulate Mash1 expression in the developing CNS. Dev. Biol. 197(1): 106-116.

Villares, R. and Cabrera, C.V. (1987). The achaete-scute gene complex of Drosophila melanogaster: conserved domains in a subset of genes required for neurogenesis and their homology to myc. Cell 50: 415-424

Wan, S., Cato, A.-M. and Skaer, H. (2000). Multiple signalling pathways establish cell fate and cell number in Drosophila Malpighian tubules, Dev. Biol. 217: 153-165.

Weiss, J. B., Ohlen, T. V., Mellerick, D. M., Dressler, G., Doe, C. Q. and Scott, M. P. (1998). Dorsoventral patterning in the Drosophila central nervous system: the intermediate neuroblasts defective homeobox gene specifies intermediate column identity. Genes Dev 12: 3591-3602.

Weatherbee, S. D., et al. (1999). Ultrabithorax function in butterfly wings and the evolution of insect wing patterns. Curr. Biol. 9(3): 109-15.

Wheeler, S. R., et al. (2003). The expression and function of the achaete-scute genes in Tribolium castaneum reveals conservation and variation in neural pattern formation and cell fate specification. Development 130:4373-81. 12900453

Yagi, Y., Suzuki, T. and Hayashi, S. (1998). Interaction between Drosophila EGF receptor and vnd determines three dorsoventral domains of the neuroectoderm. Development 125(18): 3625-3633.

Yamasaki, Y. and Nishida, Y. (2006). Mi-2 chromatin remodeling factor functions in sensory organ development through proneural gene repression in Drosophila. Dev. Growth Differ. 48(7): 411-8. Medline abstract: 16961588

Younossi-Hartenstein, A., et al. (1996). Early neurogenesis of the Drosophila brain. J. Comp. Neur. 370: 313-329

Yun, K., et al. (2002). Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon. Development 129: 5029-5040. 12397111

Zhao, C. and Emmons, S.W. (1995). A transcription factor controlling development of peripheral sense organs in C. elegans. Nature 373(6509): 74-78

Zhao, G. and Skeath, J. B. (2002). The Sox-domain containing gene Dichaete/fish-hook acts in concert with vnd and ind to regulate cell fate in the Drosophila neuroectoderm. Development 129: 1165-1174. 11874912

Zhao, G., Boekhoff-Falk, G., Wilson, B. A. and Skeath, J. B. (2007). Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS. Proc. Natl. Acad. Sci. 104(10): 3847-52. Medline abstract: 17360441

date revised: 15 December 2009

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