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Drosophila genes listed by biochemical function |
Zinc finger transcription factors A - L || M - Z
abrupt zinc finger - BTD domain
apterous LIM zinc finger domain and homeodomain
Arrowhead LIM domains and LIM homeodomain
Beadex (common alternative name: Lim-only (LMO) LIM-only protein
Boundary element-associated factor of 32kD (common alternative name: BEAF)chromatin protein required for insulator function, and chromatin structure and dynamics - required for oogenesis and zygotic development
brother of odd with entrails limited (common alternative name: bowel)zinc finger transcription factor - required for the elaboration of pattern in the tarsus - promotes morphological changes associated with joint formation during leg development
broad (common alternative name: Broad Complex) zinc finger - BTD domain
buttonhead zinc finger
castor (common alternative name: ming) zinc finger
CTCF
CCCTC-binding factor is a zinc finger transcription factor that confers enhancer blocking in all known chromatin insulators
charlatan
facilitates accumulation of proneural proteins Achaete and Scute by forming a transcriptional stimulatory loop
Chorion factor 2
zinc finger transcription factor - along with Mef2, Cf2 functions as critical regulator of the myogenic program - a mediator of EGF-R-activated dorsoventral patterning in oogenesis
clueless (preferred name: abrupt) zinc finger - BTD domain
combgap zinc finger transcription factor
crooked legsmultiple zinc finger transcription factor
cubitus interruptus zinc finger
dendritic arbor reduction 1
zinc finger transcription factor that promotes dendrite growth in part by suppressing the expression of the microtubule-severing protein Spastin
DHR3 (preferred name: Hormone receptor-like/Hr46) nuclear receptor superfamily
disconnected and disco-related zinc finger transcription factors - required for head segment identitity during Drosophila embryogenesis - required for optic lobe development and ventral appendage development
dissatisfaction nuclear receptor superfamily
doublesex novel zinc finger
drumstick zinc finger transcription factor - regulates epidermal cell differentiation and patterning in the epithelia of the foregut, hindgut, and imaginal discs
eaglenuclear receptor - zinc finger
earmuff zinc finger transcription factor - functions cell-autonomously to maintain the restricted developmental potential of the intermediate neural progenitors generated by type II neuroblasts in Drosophila larval brains
Ecdysone-induced protein 75B
nuclear receptor - ensures proper temporal progression of larval development
Ecdysone receptornuclear receptor - zinc finger
elbow B
Sp1-type zinc finger - specifies distinct tracheal cell fates
escargot zinc finger
fruitless zinc finger - sex determination
estrogen-related receptor
nuclear receptor - regulates a coordinate switch in gene expression that drives a metabolic program normally associated with proliferating cells - supports growth during larval development
ftz transcription factor 1 nuclear receptor - zinc finger
FTZ-F2 (preferred name: tramtrack) zinc finger
GAGA (preferred name: Trithorax like) zinc finger - BTD domain
gata-2 (preferred name: pannier) zinc finger - GATA family
GATAe GATA family zinc finger transcription factor - required downstream of serpent for the expression of specific genes in the differentiated midgut
glass zinc finger
grain (common alternative name: dGATAc) zinc finger - GATA family
hamlet zinc finger - regulates cell identity in the peripheral nervous system - a binary genetic switch that acts to repress a multiple dendritic arbor and promote single-dendrite morphology
Hepatocyte nuclear factor 4 zinc finger
hermaphrodite(C2 H2) zinc finger protein
hindsight (preferred name: pebbled) multiple zinc finger transcription factor
Hnf-4 (preferred name: Hepatocyte nuclear factor 4)nuclear receptor - zinc finger - activated by fatty acids released from triglycerides, inducing enzymes that drive fatty acid oxidation for energy production
Hormone receptor-like in 38 nuclear receptor superfamily - participates in a second ecdysteroid signaling pathway that responds to a distinct class of ecdysteroids in a manner that is independent of EcR
Hormone receptor-like in 46 nuclear receptor superfamily - a mediator of ecdysone signaling - coordinates metamorphosis by acting together with the dS6K pathway, which controls nutrient-dependent growth
Hormone receptor 51 (common alternative name: Unfulfilled)
nuclear receptor superfamily - a thiolate heme-binding protein - necessary for mushroom body axon extension and branching mutants modulate wing expansion and fertility through underlying neurological defects
Hormone receptor-like in 39 nuclear receptor superfamily - master regulator of a program for the production of female reproductive glands and other secretory tissues
Hormone-receptor-like in 78 nuclear receptor superfamily
Hormone receptor-like in 96 nuclear receptor superfamily - regulation of cholesterol and triacylglycerol homeostasis, genetic control of xenobiotic stress responses
Hr4
steroid hormone receptor - coordinates growth and maturation in Drosophila by mediating endocrine responses to the attainment of critical weight during larval development
huckebein zinc finger - terminal gap gene
hunchback zinc finger
islet LIM zinc finger domain and homeodomain
jing zinc finger transcription factor - a downstream target of slbo required for border cell migration - also plays an essential role in controlling CNS midline and tracheal cell differentiation
ken and barbie BTB-POZ domain transcription factor with C-terminal zinc finger - recruits NURF by physical interaction to engender transcriptional repression - involved in genital disc development
klumpfuss transcription factor - zinc finger - egr family
knirps steroid receptor - zinc finger
Krüppel zinc finger, gap gene, segmentation
Kruppel homolog 1 zinc finger transcription factor - mediates some of the juvenile hormone signaling in the adult abdominal epidermis and is upstream of broad in this pathway
lame duck
zinc finger transcription factor - has an essential regulatory role in the specification and function of fusion-competent myoblasts
longitudinals lacking zinc finger - BTD domain
Lyra zinc finger - target of proneural genes
Metal response element-binding Transcription Factor-1 zinc finger transcription factor known familiarly as metal transcription factor - controls heavy metal detoxification
ming (preferred name: castor) zinc finger
Muscle LIM protein at 60A LIM zinc finger domains - LIM-only protein
nervous fingers 1 (nerfin-1) zinc finger transcription factor required for the proper development of CNS commissural and connective axon fascicles
odd skipped zinc finger - pair rule gene
odd-paired zinc finger - pair rule gene
ovo zinc finger - ovarian maturation, sex determination, segment polarity
pannier (common alternative name: dGATAa) zinc finger - GATA family
pebbled multiple zinc finger transcription factor
pita (alternative name: spotted dick) zinc finger transcription factor that serves as an activator of expression of a set of genes required for initiation of DNA replication
pleiohomeotic zinc finger - Polycomb group
poils au dos zinc finger transcription factor - repressor of achaete and scute during bristle development
polyhomeotic proximal & distal zinc finger - Polycomb group
Posterior sexcombs zinc finger - ring motif - Polycomb group
putzig zinc finger transcription factor that acts as key regulator of cell proliferation and as a positive of Notch target genes
rotund
transcription factor - zinc finger - required for proper imaginal disc development
schnurri zinc finger - target of DPP
scratch transcription factor - zinc finger - panneural repressor
scribbler novel protein with a single zinc finger
senseless (preferred name: Lyra) zinc finger - target of proneural genes
sequoia zinc finger - required for specification of a subset of neurons - functions in regulating dendrite and axon development
serpent (common alternative name: dGATAb) zinc finger - GATA family
seven up transcription factor - orphan nuclear receptor - zinc finger
Sex combs on midleg
Polycomb group - C2C2 type zinc finger
shuttle craft zinc finger, C4HC3 type (PHD finger), and RD-domain protein
snail zinc finger - DV polarity
spalt zinc finger - PRDII-BF1 homolog
squeeze zinc finger transcription factor - regulates neuropeptidergic cellular identity and FMRFamide expression
stripe zinc finger - muscle development
sunspot zinc finger transcription factor that interacts with Armadillo - acts downstream of wingless to positively regulate the proliferation of imaginal disc cells and the endoreplication of salivary gland cells - activates E2F-1 and PCNA expression
suppressor of Hairy wing zinc fingers and leucine zipper - binds gypsy insulator element
Suppressor of variegation 3-7
chromatin constituent - zinc finger protein - required for X-restricted dosage compensation complex targeting
tailless nuclear receptor - zinc finger
teashirt zinc finger
tramtrack (common alternative name: FTZ-F2) zinc finger - BTD domain
trithorax zinc finger - trithorax group
Trithorax-like (common alternative name: GAGA) GAGA - Zinc finger, BTD domain
u-shaped multiple zinc finger protein
ultraspiracle RXR homolog - nuclear receptor
vielfaltig (common alternative name: zelda) zinc finger transcription factor - functions in the cellular blastoderm to activate many genes essential for cellularization, sex determination and pattern formation
Zinc-finger protein
zinc finger transcription factor required for the expression and asymmetric localization of aPKC, thus establishing cell polarity and controlling neuroblast self-renewal
Zinc finger protein RP-8
zinc finger domain transcription factor - essential for hematopoiesis - regulates cell proliferation through modifiying the function of the centrosome - regulates the level and localization of cell-cycle components
Zn finger homeodomain 1 zinc finger domain and homeodomain protein - mutation results in various degrees of local errors in mesodermal cell fate or positioning
Zn finger homeodomain 2
transcription factor - zinc finger domain and homeodomain - required for correct proximal wing development
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Drosophila genes listed by biochemical function
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