REFERENCES (part 1/2)

Abe, P. and Takeichi, M. (2007). NMDA-receptor activation induces Calpain-mediated β-catenin cleavages for triggering gene expression. Neuron 53: 387-397. Medline abstract: 17270735

Abdou, M., et al (2011). Wnt signaling cross-talks with JH signaling by suppressing Met and gce expression. PLoS One 6(11): e26772. PubMed Citation: 22087234

Aberle, H., et al. (1996). Single amino acid substitutions in proteins of the armadillo gene family abolish their binding to alpha-catenin. J. Biol. Chem. 271: 1520-1526. PubMed Citation: 8576147

Aberle, H., et al. (1997). ß-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 16(13): 3797-3804. PubMed Citation: 9233789

Acosta, H., López, S. L., Revinski, D. R. and Carrasco, A. E. (2011). Notch destabilises maternal β-catenin and restricts dorsal-anterior development in Xenopus. Development 138(12): 2567-79. PubMed Citation: 21610033

Adachi, S., et al. (2004). Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling. Cancer Res. 64(23): 8496-501. 15574752

Adelman, K., et al. (2006). Drosophila paf1 modulates chromatin structure at actively transcribed genes. Mol. Cell. Biol. 26: 250-260. Medline abstract: 16354696

Agathocleous, M., et al. (2009). A directional Wnt/beta-catenin-Sox2-proneural pathway regulates the transition from proliferation to differentiation in the Xenopus retina. Development 136(19): 3289-99. PubMed Citation: 19736324

Ahmed, Y., et al. (1998). Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development. Cell 93(7): 1171-1182. PubMed Citation: 9657150

Ahmed, Y., Nouri, A. and Wieschaus, E. (2002). Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development. Development 129: 1751-1762. 11923210

Akong, K., McCartney, B. M. and Peifer, M. (2002). Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations. Dev. Biol. 250: 71-90. PubMed Citation: 12297097

Allard, S., et al. (2000). Molecular mechanisms of hormone-mediated Müllerian duct regression: involvement of beta-catenin. Development 127: 3349-3360. PubMed Citation: 10887090

Amit, S., et al. (2002). Axin-mediated CKI phosphorylation of ß-catenin at Ser 45: a molecular switch for the Wnt pathway. Genes Dev. 16: 1066-1076. 12000790

Angelats, C., et al. (2001). Cubitus interruptus acts to specify naked cuticle in the trunk of Drosophila embryos. Dev. Biol. 241(1): 132-144. 11784100

Angerer, L. M., Newman, L. A. and Angerer, R. C. (2005). SoxB1 downregulation in vegetal lineages of sea urchin embryos is achieved by both transcriptional repression and selective protein turnover. Development 132: 999-1008. 15689377

Aoki, M., et al. (1999). Nuclear endpoint of wnt signaling: neoplastic transformation induced by transactivating lymphoid-enhancing factor 1. Proc. Natl. Acad. Sci. 96(1): 139-44. PubMed Citation: 9874785

Axelrod, J. D., Matsuno, K., Artavanis Tsakonas, S., and Perrimon, N. (1996). Interaction between Wingless and Notch signaling pathways mediated by Dishevelled. Science 271: 1826-1832. PubMed Citation: 8596950

Azzolin, L., Panciera, T., Soligo, S., Enzo, E., Bicciato, S., Dupont, S., Bresolin, S., Frasson, C., Basso, G., Guzzardo, V., Fassina, A., Cordenonsi, M. and Piccolo, S. (2014). YAP/TAZ incorporation in the beta-Catenin destruction complex orchestrates the Wnt response. Cell 158: 157-170. PubMed ID: 24976009

Bahmanyar, S., et al. (2008). β-Catenin is a Nek2 substrate involved in centrosome separation. Genes Dev. 22: 91-105. PubMed citation: 18086858

Bai, J. Uehara, Y. and Montell, D. J. (2000). Regulation of invasive cell behavior by Taiman, a Drosophila protein related to AIB1, a steroid receptor coactivator amplified in breast cancer. Cell 103: 1047-1058. 11163181

Bajpai, R., et al. (2004). Drosophila Twins regulates Armadillo levels in response to Wg/Wnt signal. Development 131: 1007-1016. 14973271

Balakirev, M. Y., Tcherniuk, S. O., Jaquinod, M. and Chroboczek, J. (2003). Otubains: A new family of cysteine proteases in the ubiquitin pathway. EMBO Rep. 4: 517-522. PubMed Citation: 12704427

Balmer, S., Dussert, A., Collu, G. M., Benitez, E., Iomini, C. and Mlodzik, M. (2015). Components of Intraflagellar Transport complex A function independently of the cilium to regulate canonical Wnt signaling in Drosophila. Dev Cell 34(6):705-18. PubMed ID: 26364750

Bamji, S. X., et al. (2003). Role of ß-Catenin in synaptic vesicle localization and presynaptic assembly. Neuron 40: 719-731. 14622577

Baonza, A. and Freeman, M. (2002). Control of Drosophila eye specification by Wingless signaling. Development 129: 5313-5322. 12403704

Barker, N., et al. (2001). The chromatin remodeling factor Brg-1 interacts with ß-catenin to promote target gene activation. EMBO J. 20: 4935-4943. 11532957

Batlle, E., et al. (2002). ß-Catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/EphrinB. Cell 111: 251-263. 12408869

Bauer, A., Huber, O. and Kemler, R. (1998). Pontin52, an interaction partner of beta-catenin, binds to the TATA box binding protein. Proc. Natl. Acad. Sci. 95(25): 14787-92. PubMed Citation: 9843967

Beanan, M. J., Feledy, J. A. and Sargent, T. D. (2000). Regulation of early expression of Dlx3, a Xenopus anti-neural factor, by beta-catenin signaling. Mech. Dev. 227-235. PubMed Citation: 10704847

Behrens, J., et al. (1996). Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 382: 638-642. PubMed Citation: 8757136

Behrens, J., et al. (1998). Functional interaction of an axin homolog, Conductin, with beta-Catenin, APC, and GSK3beta. Science 280(5363): 596-599. PubMed Citation: 9554852

Bejsovec, A. and Wieschaus, E. (1993). Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos. Development 119: 501-517. PubMed Citation: 8287799

Benchabane, H., et al. (2008). Adenomatous polyposis coli is present near the minimal level required for accurate graded responses to the Wingless morphogen. Development 135: 963-971. PubMed Citation: 18234723

Benchabane, H., et al. (2011). Jerky/Earthbound facilitates cell-specific Wnt/Wingless signalling by modulating beta-catenin-TCF activity. EMBO J. 30: 1444-1458. PubMed Citation: 21399610

Benhamouche, S., et al. (2006). Apc tumor suppressor gene is the 'zonation-keeper' of mouse liver. Dev. Cell 10(6): 759-70. 16740478

Bertrand, V. and Hobert, O. (2009). Linking asymmetric cell division to the terminal differentiation program of postmitotic neurons in C. elegans. Dev. Cell 16(4): 563-75. PubMed Citation: 19386265

Bierkamp, C., et al. (1999). Desmosomal localization of beta-catenin in the skin of plakoglobin null-mutant mice. Development 126(2): 371-381. PubMed Citation: 9847250

Bikkavilli, R. K. and Malbon, C. C. (2010). Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of beta-catenin mRNA. J. Cell Sci. 123(Pt 8): 1352-62. PubMed Citation: 20332102

Blythe, S. A., et al. et al. (2010). beta-Catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2. Dev. Cell 19(2): 220-31. PubMed Citation: 20708585

Boulay, J. L., Stiefel, U., Taylor, E., Dolder, B., Merlo, A. and Hirth, F. (2009). Loss of heterozygosity of TRIM3 in malignant gliomas. BMC Cancer 9: 71. PubMed ID: 19250537

Boulton, S. J., et al. (2000). A role for ebi in neuronal cell cycle control. EMBO J. 19(20): 5376-86. PubMed Citation: 11032805

Brancolini, C., et al. (1997). Dismantling cell-cell contacts during apoptosis is coupled to a caspase-dependent proteolytic cleavage of beta-catenin. J. Cell Biol. 139(3): 759-771. PubMed Citation: 9348292

Brannon, M., et al. (1997). A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus. Genes Dev. 11(18): 2359-2370. PubMed Citation: 9308964

Brault, V., et al. (2001). Inactivation of the ß-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development 128: 1253-1264. 11262227

Brembeck, F. H., et al. (2004). Essential role of BCL9-2 in the switch between ß-catenin's adhesive and transcriptional functions. Genes Dev. 18(18): 2225-30. 15371335

Brennan, K., et al. (1999). Wingless modulates the effects of dominant negative notch molecules in the developing wing of Drosophila. Dev. Biol. 216(1): 210-29. PubMed Citation: 10588873

Brunner, E., et al. (1997). pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila. Nature 385: 829-933. PubMed Citation: 9039917

Buceta, J., Herranz, H., Canela-Xandri, O., Reigada, R., Sagues, F. and Milan, M. (2007). Robustness and stability of the gene regulatory network involved in DV boundary formation in the Drosophila wing. PLoS ONE 2: e602. PubMed Citation: 17622347

Buchman, J. J., Durak, O. and Tsai, L. H. (2011). ASPM regulates Wnt signaling pathway activity in the developing brain. Genes Dev. 25(18): 1909-14. PubMed Citation: 21937711

Cantera, R., et al. (2002). Mutations in spalt cause a severe but reversible neurodegenerative phenotype in the embryonic central nervous system of Drosophila melanogaster. Development 129: 5577-5586. 12421699

Capdevila, J., Tabin, C. and Johnson, R. L. (1998). Control of dorsoventral somite patterning by Wnt-1 and beta-Catenin. Dev. Biol. 193(2): 182-194. PubMed Citation: 9473323

Carl, M., et al. (2007). Wnt/Axin1/beta-catenin signaling regulates asymmetric nodal activation, elaboration, and concordance of CNS asymmetries. Neuron 55(3): 393-405. PubMed citation: 17678853

Cavallo, R. A., et al. (1998). Drosophila Tcf and Groucho interact to repress Wingless signalling activity. Nature 395(6702): 604-8. PubMed Citation: 9783586

Cavodeassi, F., et al. (2005). Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/ß-Catenin pathway. Neuron 47: 43-56. 15996547

Celso, C. L., Prowse, D. M. and Watt, F. M. (2004). Transient activation of ß-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumors. Development 131: 1787-1799. 15084463

Chambers, M., Turki-Judeh, W., Kim, M. W., Chen, K., Gallaher, S. D. and Courey, A. J. (2017). Mechanisms of Groucho-mediated repression revealed by genome-wide analysis of Groucho binding and activity. BMC Genomics 18(1): 215. PubMed ID: 28245789

Chen, H. J., et al. (2006). The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway. Genes Dev. 20(14): 1933-45. 16815997

Chen, R. H., Ding, W. V., McCormick, F. (2000). Wnt signaling to beta-catenin involves two interactive components. Glycogen synthase kinase-3beta inhibition and activation of protein kinase C. J. Biol. Chem. 275(23): 17894-9. PubMed Citation: 10749878

Chen, Y. T., Stewart, D. B. and Nelson, W. J. (1999). Coupling assembly of the E-Cadherin/beta-Catenin complex to efficient endoplasmic reticulum exit and basal-lateral membrane targeting of E-Cadherin in polarized MDCK cells. J. Cell Biol. 144(4): 687-699. PubMed Citation: 10037790

Chitaev, N. A., et al. (1996). The binding of plakoglobin to desmosomal cadherins: patterns of binding sites and topogenic potential. J. Cell Biol. 133: 359-369. PubMed Citation: 8609168

Cho, S. H. and Cepko, C. L. (2006). Wnt2b/β-catenin-mediated canonical Wnt signaling determines the peripheral fates of the chick eye. Development 133(16): 3167-77. 16854977

Chodaparambil, J. V., Pate, K. T., Hepler, M. R., Tsai, B. P., Muthurajan, U. M., Luger, K., Waterman, M. L. and Weis, W. I. (2014). Molecular functions of the TLE tetramerization domain in Wnt target gene repression. EMBO J 33(7): 719-731. PubMed ID: 24596249

Choi, S. H., Estaras, C., Moresco, J. J., Yates, J. R. and Jones, K. A. (2013). alpha-Catenin interacts with APC to regulate beta-catenin proteolysis and transcriptional repression of Wnt target genes. Genes Dev 27: 2473-2488. PubMed ID: 24240237

Ciruna, B. and Rossant, J. (2001). FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak. Dev. Cell 1: 37-49. PubMed Citation: 11703922

Cliffe, A., Hamada, F. and Bienz, M. (2003). A role of Dishevelled in relocating Axin to the plasma membrane during Wingless signaling. Curr. Biol. 13: 960-966. 12781135

Colosimo, P. F. and Tolwinski, N. S. (2006). Wnt, Hedgehog and junctional Armadillo/beta-catenin establish planar polarity in the Drosophila embryo. PLoS ONE 1:e9. PubMed citation: 17183721

Colnot, S., Decaens, T., Niwa-Kawakita, M., Godard, C., Hamard, G., Kahn, A., Giovannini, M. and Perret, C. (2004). Liver-targeted disruption of Apc in mice activates ß-catenin signaling and leads to hepatocellular carcinomas. Proc. Natl. Acad. Sci. 101: 17216-17221. 15563600

Conacci-Sorrell, M. E., et al. (2002). Nr-CAM is a target gene of the ß-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesis. Genes Dev. 16: 2058-2072. 12183361

Cong, F., Schweizer, L. and Varmus, H. (2004). Wnt signals across the plasma membrane to activate the ß-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP. Development 131: 5103-5115. 15459103

Corbit, K. C., et al. (2008). Kif3a constrains β-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms. Nat. Cell Biol. 10: 70-76. PubMed Citation: 18084282

Cordero, J. B., Larson, D. E., Craig, C. R., Hays, R. and Cagan, R. (2007). Dynamic decapentaplegic signaling regulates patterning and adhesion in the Drosophila pupal retina. Development 134(10): 1861-71. Medline abstract: 17428827

Costa, M., et al. (1998). A putative catenin-cadherin system mediates morphogenesis of the Caenorhabditis elegans embryo. J. Cell Biol. 141(1): 297-308

Coste, A. L., et al. (1998). Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. Proc. Natl. Acad. Sci. 95(15): 8847-8851

Cox, R. T., Kirkpatrick, C. and Peifer, M. (1996), Armadillo is required for adherens junction assembly, cell polarity and morphogenesis during Drosophila embryogenesis. J. Cell Biol. 134: 133-148

Cox, R. T., et al. (1999). Membrane-tethered Drosophila Armadillo cannot transduce Wingless signal on its own. Development 126: 1327-1335

Cox, R. T., et al. (2000). A screen for mutations that suppress the phenotype of Drosophila armadillo, the ß-catenin homolog. Genetics 155: 1725-1740

Daniels, D. L. and Weis, W. I. (2002). ICAT inhibits ß-Catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules. Molec. Cell 10: 573-584. 12408825

Darras, S., et al. (1997). Animal and vegetal pole cells of early Xenopus embryos respond differently to maternal dorsal determinants: implications for the patterning of the organiser. Development 124(21): 4275-4286

Davidson, E. H., et al. (2002). A provisional regulatory gene network for specification of endomesoderm in the sea urchin embryo. Dev. Biol. 246: 162-190. 12027441

Davidson, G., Wu, W., Shen, J., Bilic, J., Fenger, U., Stannek, P., Glinka, A. and Niehrs, C. (2005). Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction. Nature 438: 867-872. PubMed ID: 16341016

De Graeve, F. M., et al. (2012). Drosophila apc regulates delamination of invasive epithelial clusters. Dev. Biol. 368(1): 76-85. PubMed Citation: 22627290

de la Roche, M. and Bienz, M. (2007). Wingless-independent association of Pygopus with dTCF target genes. Curr. Biol. 17(6): 556-61. Medline abstract: 17320388

Delmas, V., et al. (2007). β-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development. Genes Dev. 21(22): 2923-35. PubMed citation: 18006687

Desai, R., Sarpal, R., Ishiyama, N., Pellikka, M., Ikura, M. and Tepass, U. (2013). Monomeric α-catenin links cadherin to the actin cytoskeleton. Nat Cell Biol 15: 261-273. PubMed ID: 23417122

Desprat, N., Supatto, W., Pouille, P. A., Beaurepaire, E. and Farge, E. (2008). Tissue deformation modulates twist expression to determine anterior midgut differentiation in Drosophila embryos. Dev. Cell 15(3): 470-7. PubMed Citation: 18804441

de Vries, W. N., et al. (2004). Maternal ß-catenin and E-cadherin in mouse development. Development 131: 4435-4445. 15306566

Domingos, P. M., et al. (2001). The Wnt/ß-Catenin pathway posteriorizes neural tissue in Xenopus by an indirect mechanism requiring FGF signaling. Dev. Bio. 239: 148-160

Dominguez, I., et al. (2004). Protein kinase CK2 is required for dorsal axis formation in Xenopus embryos. Dev. Biol. 274: 110-124. 15355792

Drees, F., Pokutta, S., Yamada, S., Nelson, W. J. and Weis, W. I. (2005). α-catenin is a molecular switch that binds E-cadherin-ß-catenin and regulates actin-filament assembly. Cell 123(5): 903-15. 16325583

Eisenmann, D. M., et al. (1998). The beta-catenin homolog BAR-1 and LET-60 Ras coordinately regulate the Hox gene lin-39 during Caenorhabditis elegans vulval development. Development 125(18): 3667-3680. PubMed Citation: 9716532

Eleftheriou, A., Yoshida, M. and Henderson, B. R. (2001). Nuclear export of human ß-Catenin can occur independent of CRM1 and the adenomatous polyposis coli tumor suppressor. J. Biol. Chem. 276: 25883-25888. 11337505

Enshell-Seijffers, D., et al. (2010). β-catenin activity in the dermal papilla regulates morphogenesis and regeneration of hair. Dev. Cell 18: 633-642. PubMed Citation: 20439431

Fagotto, R., Guger, K. and Gumbiner, B. M. (1997). Induction of the primary dorsalizing center in Xenopus by the Wnt/GSK/ß-catenin signaling pathway, but not by Vg1, Activin or Noggin. Development 124: 453-460. PubMed Citation: 9053321

Fagotto, F., Gluck, U. and Gumbiner, B. M. (1998). Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin. Curr. Biol. 8(4): 181-190. PubMed Citation: 9501980

Fagotto, F., et al. (1999). Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization. J. Cell Biol. 145(4): 741-56. PubMed Citation: 10330403

Fan, M. J. and Sokol, S. Y. (1997). A role for Siamois in Spemann organizer formation. Development 124(13): 2581-2589. PubMed Citation: 9217000

Fancy, S. P., et al. (2009). Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Genes Dev. 23(13): 1571-85. PubMed Citation: 19515974

Fang, M., Li, J., Blauwkamp, T., Bhambhani, C., Campbell, N. and Cadigan, K. M. (2006). C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila. EMBO J. 25(12): 2735-45. 16710294

Farge, E. (2003). Mechanical induction of Twist in the Drosophila foregut/stomodeal primordium. Curr. Biol. 13: 1365-1377. 12932320

Faux, M. C., et al. (2004). Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion. J. Cell Sci. 117(Pt 3): 427-39. 14679305

Feng, Y., et al. (2007). Drosophila split ends homologue SHARP functions as a positive regulator of Wnt/β-Catenin/T-cell factor signaling in neoplastic transformation, Cancer Res. 67: 485-491. PubMed Citation: 17234755

Fiedler, M., Sanchez-Barrena, M. J., Nekrasov, M., Mieszczanek, J., Rybin, V., Muller, J., Evans, P. and Bienz, M. (2008). Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex. Mol Cell 30(4): 507-518. PubMed ID: 18498752

Fiedler, M., Graeb, M., Mieszczanek, J., Rutherford, T. J., Johnson, C. M. and Bienz, M. (2015). An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP. Elife 4. PubMed ID: 26312500

Flack, J. E., Mieszczanek, J., Novcic, N. and Bienz, M. (2017). Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5. Mol Cell 67(2): 181-193.e185. PubMed ID: 28689657

Fleckenstein, D., et al. (1998). Yel013p (Vac8p), an armadillo repeat protein related to plakoglobin and importin alpha, is associated with the yeast vacuole membrane. J. Cell Sci. 111(20): 3109-3118. PubMed Citation: 9739084

Freeman, M. and Bienz, M. (2001). EGF receptor/Rolled MAP kinase signalling protects cells against activated Armadillo in the Drosophila eye. EMBO Reports 2: 157-162. 11258709

Fujita, Y., et al. (2002). Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex. Nat. Cell Biol. 4: 222-231. 11836526

Funayama, N., et al. (1995). Embryonic axis induction by the armadillo repeat domain of beta-Catenin: evidence for intracellular signaling. J. Cell Biol. 128: 959-968

Gallet, A., et al. (1998). Trunk-specific modulation of Wingless signalling in Drosophila by Teashirt binding to Armadillo. Curr. Biol. 8(16): 893-902

Gallet, A., et al. (1999). The C-terminal domain of Armadillo binds to hypophosphorylated Teashirt to modulate Wingless signalling in Drosophila. EMBO J. 18(8): 2208-2217

Gat, U., et al. (1998). De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell 95(5): 605-14

Gault, W. J., Olguin, P., Weber, U. and Mlodzik, M. (2012). Drosophila CK1-gamma, gilgamesh, controls PCP-mediated morphogenesis through regulation of vesicle trafficking. J Cell Biol 196: 605-621. PubMed ID: 22391037

Geis, K., et al. (1998). Expression of the Armadillo family member p120cas1B in Xenopus embryos affects head differentiation but not axis formation. Dev. Genes Evol. 207(7): 471-81

Goichberg, P., et al. (2001). Recruitment of ß-catenin to cadherin-mediated intercellular adhesions is involved in myogenic induction. J. Cell Sci. 114: 1309-1319. 11256997

Gold, D. A., et al. (2003). RORalpha coordinates reciprocal signaling in cerebellar development through Sonic hedgehog and calcium-dependent pathways. Neuron 40: 1119-1131. 14687547

Gonzalez-Reyes, A. and Johnston, D. S. (1998). The Drosophila AP axis is polarised by the cadherin-mediated positioning of the oocyte. Development 125(18): 3635-3644. PubMed Citation: 9716529

Goessling, W., et al. (2009). Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell 136(6): 1136-47. PubMed Citation: 19303855

Goss, A. M., et al. (2009). Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut. Dev. Cell 17(2): 290-8. PubMed Citation: 19686689

Gotz, J., et al. (2000). Distinct role of protein phosphatase 2A subunit Calpha in the regulation of E-cadherin and beta-catenin during development. Mech. Dev. 93: 83-93. PubMed Citation: 10781942

Graham, T. A., et al. (2000). Crystal structure of a beta-Catenin/Tcf complex. Cell 103: 885-896. PubMed Citation: 11136974

Graham, T. A., et al. (2002). The crystal structure of the ß-Catenin/ICAT complex reveals the inhibitory mechanism of ICAT Molec. Cell 10: 563-571. 12408824

Greaves, S., et al. (1999). A screen for identifying genes interacting with Armadillo, the Drosophila homolog of ß-catenin. Genetics 153: 1753-1766. PubMed Citation: 10581282

Grevengoed, E. E., Loureiro, J. J., Jesse, T. L. and Peifer, M. (2001). Abelson kinase regulates epithelial morphogenesis in Drosophila. J. Cell Biol. 155: 1185-1198. 11756472

Guger, K. A. and Gumbiner, B. M. (2000). A mode of regulation of beta-Catenin signaling activity in Xenopus embryos independent of its levels. Dev. Bio. 223: 441-448. PubMed Citation: 10882528

Guo, X., et al. (2004). Wnt/beta-catenin signaling is sufficient and necessary for synovial joint formation. Genes Dev. 18(19): 2404-17. 15371327

Hall, E. T. and Verheyen, E. M. (2015). Ras-activated Dsor1 promotes Wnt signaling in Drosophila development. J Cell Sci 128(24):4499-511. PubMed ID: 26542023

Hamada, F., et al. (1999). Negative regulation of Wingless signaling by D-Axin, a Drosophila homolog of Axin. Science 283(5408): 1739-42. PubMed Citation: 10073940

Hamada, F. and Bienz, M. (2004). The APC tumor suppressor binds to C-terminal binding protein to divert nuclear ß-Catenin from TCF. Dev. Cell 7: 677-685. 15525529

Hamilton, F. S., Wheeler, G. N. and Hoppler, S. (2001). Difference in XTcf-3 dependency accounts for change in response to ß-catenin-mediated Wnt signalling in Xenopus blastula. Development 128: 2063-2073. PubMed Citation: 11493528

Haussmann I., White, K. and Soller, M. (2008). Erect wing regulates synaptic growth in Drosophila by integration of multiple signaling pathways. Genome Biol. 9: R73. PubMed Citation: 18419806

Hayward, P., Balayo, T. and Martinez Arias, A. (2006). Notch synergizes with axin to regulate the activity of armadillo in Drosophila. Dev. Dyn. 235(10): 2656-66. Medline abstract: 16881048

Hayasi, S., et al. (1997). A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates ß-catenin but its zygotic expression is not essential for the regulation of Armadillo. Proc. Natl. Acad. Sci. 94: 242-247. PubMed Citation: 8990193

Hayward, P., Brennan, K., Sanders, P., Balayo, T., DasGupta, R., Perrimon, N. and Martinez Arias, A. (2005). Notch modulates Wnt signalling by associating with Armadillo/ß-catenin and regulating its transcriptional activity. Development 132: 1819-1830. 15772135

Hazan, R. B., Kang, L., Roe, S., Borgen, P. I., and Rimm, D. L. (1997). Vinculin is associated with the E-cadherin adhesion complex. J. Biol. Chem. 272: 32448-32453. 9405455

He T.-C., et al. (1998). Identification of c-MYC as a target of the APC pathway. Science 281(5382): 1509-1512

Heasman, J., Kofron, M. and Wylie, C. (2000). beta-Catenin signaling activity dissected in the early Xenopus embryo: A novel antisense approach. Dev. Bio. 222: 124-134

Hendriksen, J., Fagotto, F., van der Velde, H., van Schie, M., Noordermeer, J. and Fornerod, M. (2005). RanBP3 enhances nuclear export of active ß-catenin independently of CRM1. J. Cell Biol. 171(5): 785-97. 16314428

Herren, B., et al. (1998). Cleavage of beta-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: evidence for a role for caspases and metalloproteinases. Mol. Biol. Cell 9(6): 1589-1601

Hilton, E., Rex, M. and Old, R. (2003). VegT activation of the early zygotic gene Xnr5 requires lifting of Tcf-mediated repression in the Xenopus blastula. Mech. Dev. 120: 1127-1138. 14568102

Hirabayashi, Y., et al. (2004). The Wnt/ß-catenin pathway directs neuronal differentiation of cortical neural precursor cells. Development 131: 2791-2801. 15142975

Hobmayer, B., et al. (2000). WNT signaling molecules act in axis formation in the diploblastic metazoan Hydra. Nature 407: 186-189

Hoffmans, R. and Basler, K. (2004). Identification and in vivo role of the Armadillo-Legless interaction. Development 131: 4393-4400. 15294866

Hoffmans, R., Stadeli, R. and Basler, K. (2005). Pygopus and legless provide essential transcriptional coactivator functions to armadillo/β-catenin. Curr. Biol. 15(13): 1207-11. 16005293

Hoffmans, R. and Basler, K. (2007). BCL9-2 binds Arm/β-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling. Mech. Dev. 124(1): 59-67. 17113272

Hooper, J. E. (1994). Distinct pathways for autocrine and paracrine Wingless signalling in Drosophila embryos. Nature 372: 461-464

Hsu, S. C., Galceran, J., Grosschedl, R. (1998). Modulation of transcriptional regulation by LEF-1 in response to wnt-1 signaling and association with beta-catenin. Mol. Cell. Biol. 18(8): 4807-4818

Hu, M. C., Piscione, T. D. and Rosenblum, N. D. (2003). Elevated SMAD1/ß-catenin molecular complexes and renal medullary cystic dysplasia in ALK3 transgenic mice. Development 130: 2753-2766. 12736218

Hu, M. C. and Rosenblum, N. D. (2005). Smad1, ß-catenin and Tcf4 associate in a molecular complex with the Myc promoter in dysplastic renal tissue and cooperate to control Myc transcription. Development 132: 215-225. 15576399

Huang, S., Shetty, P., Robertson, S. M. and Lin, R. (2007). Binary cell fate specification during C. elegans embryogenesis driven by reiterated reciprocal asymmetry of TCF POP-1 and its coactivator β-catenin SYS-1. Development 134(14): 2685-95. PubMed citation; Online text

Huber, A. H., Nelson, W. J. and Weis, W. I. (1997). Three-dimensional structure of the armadillo repeat region of beta-catenin. Cell 90(5): 871-882.

Huber, O., et al. (1996). Nuclear localization of ß-catenin by interaction with transcription factor LEF-1. Mech. Dev. 56: 3-10

Huber, O., Krohn, M. and Kemler, R. (1997). A specific domain in alpha-catenin mediates binding to beta-catenin or plakoglobin. J. Cell Sci. 110:1759-1765

Huber, A. H. and Weis, W. I. (2001). The structure of the ß-Catenin/E-Cadherin complex and the molecular basis of diverse ligand recognition by ß-Catenin. Cell 105: 391-402. 11348595

Huelsken, J., et al. (2001). ß-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 105: 533-545. 11371349

Huh, S. H. and Ornitz, D. M. (2010). Beta-catenin deficiency causes DiGeorge syndrome-like phenotypes through regulation of Tbx1. Development 137(7): 1137-47. PubMed Citation: 20215350

Hulsken, J., Behrens, J. and Birchmeier, W. (1994).Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection. Curr. Opin. Cell Biol. 6: 711-716

Hunter, C. and Wieschaus, E. (2000). Regulated expression of nullo is required for the formation of distinct apical and basal adherens junctions in the Drosophila blastoderm. J. Cell Bio. 150: 391-402. 10908580

Hutcheson, D. A., Zhao, J., Merrell, A., Haldar, M. and Kardon, G. (2009). Embryonic and fetal limb myogenic cells are derived from developmentally distinct progenitors and have different requirements for beta-catenin. Genes Dev. 23(8): 997-1013. PubMed Citation: 19346403

Ikeda, S., et al. (1998). Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin. EMBO J. 17(5): 1371-1384.

Ilyas, M., et al. (1997). Beta-catenin mutations in cell lines established from human colorectal cancers. Proc. Natl. Acad. Sci. 94(19): 10330-10334

Imai, K. S., Satoh, N. and Satou, Y. (2002). An essential role of a FoxD gene in notochord induction in Ciona embryos. Development 129: 3441-3453. 12091314

Imamura, Y., et al. (1999). Functional domains of alpha-Catenin required for the strong state of Cadherin-based cell adhesion. J. Cell Biol. 144(6): 1311-1322

Ishitani, T., (1999). The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF. Nature 399: 798-802. Medline abstract: 10391247

Ishitani, T., Ninomiya-Tsuji, J. and Matsumoto, K. (2003). Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling. Mol. Cell. Biol. 23: 1379-1389. Medline abstract: 12556497

Iwai, Y., Usui, T., Hirano, S., Steward, R., Takeichi, M. and Uemura, T. (1997). Axon patterning requires DN-cadherin, a novel neuronal adhesion receptor, in the Drosophila embryonic CNS. Neuron 19(1): 77-89

Jaiswal, M., Agrawal, N. and Sinha, P. (2006). Fat and Wingless signaling oppositely regulate epithelial cell-cell adhesion and distal wing development in Drosophila. Development 133(5): 925-35. 16452097

Jemc, J. C., Milutinovich, A. B., Weyers, J. J., Takeda, Y. and Van Doren, M. (2012). raw Functions through JNK signaling and cadherin-based adhesion to regulate Drosophila gonad morphogenesis. Dev Biol 367: 114-125. PubMed ID: 22575490

Jezowska, B., Fernandez, B. G., Amandio, A. R., Duarte, P., Mendes, C., Bras-Pereira, C. and Janody, F. (2011). A dual function of Drosophila capping protein on DE-cadherin maintains epithelial integrity and prevents JNK-mediated apoptosis. Dev Biol 360: 143-159. Pubmed: 21963538

Jiang, J. and Struhl, G. (1998). Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb. Nature 391(6666): 493-496. PubMed ID: 9461217

Kadoch, C. and Crabtree, G. R. (2015). Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics. Sci Adv 1(5): e1500447. PubMed ID: 26601204

Kang, D. E., et al. (2002). Presenilin couples the paired phosphorylation of ß-Catenin independent of Axin: Implications for ß-Catenin activation in tumorigenesis. Cell 110: 751-762. 12297048

Karnovsky, A. and Klymkowsky, M. W. (1995). Anterior axis duplication in Xenopus induced by the over-expression of the cadherin-binding protein plakoglobin. Proc. Natl. Acad. Sci. 92: 4522-4526. PubMed Citation: 7753837

Katanaev, V. L., et al. (2005). Trimeric G protein-dependent Frizzled signaling in Drosophila. Cell 120: 111-122. 15652486

Kawakami, Y., et al. (2011). Islet1-mediated activation of the β-catenin pathway is necessary for hindlimb initiation in mice. Development 138(20): 4465-73. PubMed Citation: 21937598

Kelly, C., et al. (2000). Maternally controlled beta-catenin-mediated signaling is required for organizer formation in the zebrafish. Development 127: 3899-3911. PubMed ID: 10952888

Kemler, R., et al. (2004). Stabilization of ß-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast. Development 131: 5817-5824. 15525667

Kengaku, M., et al. (1998). Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud. Science 280(5367): 1274-1277. PubMed ID: 9596583

Kessler, R., Hausmann, G. and Basler, K. (2009). The PHD domain is required to link Drosophila Pygopus to Legless/β-catenin and not to histone H3. Mech. Dev. 126(8-9): 752-9. PubMed Citation: 19493659

Kiger, J. A. Jr., Natzle, J. E., Kimbrell, D. A., Paddy, M. R., Kleinhesselink, K. and Green. M. M. (2007). Tissue remodeling during maturation of the Drosophila wing. Dev. Biol. 301(1): 178-91. Medline abstract: 16962574

Kim, H., Wu, J., Ye, S., Tai, C. I., Zhou, X., Yan, H., Li, P., Pera, M. and Ying, Q. L. (2013). Modulation of β-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal. Nat Commun 4: 2403. PubMed ID: 23985566

Kim, L. and Wong, T. W. (1998). Growth factor-dependent phosphorylation of the actin-binding protein cortactin is mediated by the cytoplasmic tyrosine kinase FER. J. Biol. Chem. 273(36):23542-8. PubMed ID: 9722593

Kimelman, D., Christian, J. L. and Moon, R. T. (1992). Synergistic principles of development: overlapping patterning systems in Xenopus mesoderm induction. Development 116: 1-9. PubMed ID: 1483380

Kimura, T., et al. (2006) The stabilization of β-catenin leads to impaired primordial germ cell development via aberrant cell cycle progression. Dev. Biol. 27: 545-553. PubMed Citation: 17055474

Kimura-Yoshida, C., et al. (2005). Canonical Wnt signaling and its antagonist regulate anterior-posterior axis polarization by guiding cell migration in mouse visceral endoderm. Dev. Cell 9: 639-650. 16256739

Kioussi, C., et al. (2002). Identification of a Wnt/Dvl/ß-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development. Cell 111: 673-685. 12464179

Kishida, S., et al. (1999). DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability. Mol. Cell. Biol. 19(6): 4414-22

Kitagawa, M., et al. (1999). An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin. EMBO J. 18(9): 2401-2410

Knudsen, K. A., Soler, A. P., Johnson, K. R. and Wheelock, M. J. (1995). Interaction of α-actinin with the cadherin/catenin cell-cell adhesion complex via α-catenin. J. Cell Biol. 130: 67-77. 7790378

Kolligs, F. T., et al. (2000). gamma-Catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. Genes Dev. 14: 1319-1331

Komori, H., Xiao, Q., McCartney, B. M. and Lee, C. Y. (2013). Brain tumor specifies intermediate progenitor cell identity by attenuating beta-catenin/Armadillo activity. Development 141(1): 51-62. PubMed ID: 24257623

Korinek, V., et al. (1997). Constitutive transcriptional activation by a ß-Catenin-Tcf complex in APC-/- colon carcinoma. Science 275: 1784-87.

Korswagen, H. C., (2000). Distinct beta-catenins mediate adhesion and signaling functions in C. elegans. Nature 406: 527-532

Koslov, E. R., et al. (1997). alpha-catenin can form asymmetric homodimeric complexes and/or heterodimeric complexes with beta-catenin. J. Biol. Chem. 272(43): 27301-27306

Kramps, T. (2002). Wnt/Wingless signaling requires BCL9/Legless-mediated recruitment of Pygopus to the nuclear ß-Catenin-TCF complex Cell 109: 47-60. 11955446

Krieghoff, E., Behrens, J. and Mayr, B. (2006). Nucleo-cytoplasmic distribution of β-catenin is regulated by retention. J. Cell Sci. 119(Pt 7): 1453-63. 16554443

Krufka, A., et al. (1998). Evidence that dorsal-ventral differences in gap junctional communication in the early Xenopus embryo are generated by beta-Catenin independent of cell adhesion effects. Dev. Biol. 200(1): 92-102.

Kubota, K., Goto, S. and Hayashi, S. (2003). The role of Wg signaling in the patterning of embryonic leg primordium in Drosophila. Dev. Biol. 257: 117-126. 12710961

Kunttas-Tatli, E., Roberts, D. M. and McCartney, B. M. (2014). Self-association of the APC tumor suppressor is required for the assembly, stability, and activity of the Wnt signaling destruction complex. Mol Biol Cell 25(21):3424-36. PubMed ID: 25208568

Kuroda S., et al. (1998). Role of IQGAP1, a target of the small GTPases cdc42 and rac1, in regulation of E-cadherin- mediated cell-cell adhesion. Science 282(5378): 832-835

Kuwahara, A., et al. (2010). Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex. Development. 2010 Apr;137(7):1035-44. PubMed Citation: 20215343

Kuzhandaivel, A., Schultz, S. W., Alkhori, L. and Alenius, M. (2014). Cilia-mediated hedgehog signaling in Drosophila. Cell Rep 7: 672-680. PubMed ID: 24768000

Kwon, Y. T., et al. (2000). Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase. Curr. Biol. 10(7): 363-72. PubMed ID: 10753743

Kypta, R. M., Su, H. and Reichardt, L. F. (1996). Association between a transmembrane protein tyrosine phospatase and the Cadherin-Catenin complex. J. Cell Biol. 134: 1519-29

Lal, M., et al. (2008). Polycystin-1 C-terminal tail associates with β-catenin and inhibits canonical Wnt signaling. Hum. Mol. Genet. 17: 3105-3117. PubMed Citation: 18632682

Lam, N., Chesney, M. A. and Kimble, J. (2006). Wnt signaling and CEH-22/tinman/Nkx2.5 specify a stem cell niche in C. elegans. Curr. Biol. 16: 287-295. 16461282

Langevin, J., et al. (2005). Drosophila exocyst components Sec5, Sec6, and Sec15 regulate DE-Cadherin trafficking from recycling endosomes to the plasma membrane. Dev. Cell 9(3): 355-76. 16224820

Larabell, C. A., et al. (1997). Establishment of the Dorso-ventral axis in Xenopus embryos is presaged by early asymmetries in ß-catenin that are modulated by the Wnt signaling pathway. J. Cell Biol. 136: 1123-36

Le Borgne, R., Bellaçhe, Y. and Schweisguth, F. (2002). Drosophila E-cadherin regulates the orientation of asymmetric cell division in the sensory organ lineage Curr. Biol. 12: 95-104. 11818059

Lecuit, T. and Wieschaus, E. (2000). Polarized insertion of new membrane from a cytoplasmic reservoir during cleavage of the Drosophila embryo. J. Cell Biol. 150(4): 849-60. 10953008

Lee, E., et al. (2003). The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway. Plos Biol. 2(3): E89. 14551908

Lee, J. H., Bassel-Duby, R., Olson, E. N. (2014) Heart- and muscle-derived signaling system dependent on MED13 and Wingless controls obesity in Drosophila. Proc Natl Acad Sci U S A 111: 9491-9496. PubMed ID: 24979807

Lee, M., et al. (2003). Distinct sites in E-cadherin regulate different steps in Drosophila tracheal tube fusion. Development 130: 5989-5999. 14597571

Lee, W., Swarup, S., Chen, J., Ishitani, T. and Verheyen, E. M. (2009) Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of β-catenin/Arm and stimulation of target gene expression. Development 136(2): 241-51. PubMed Citation: 19088090

Lemaire, P., Garrett, N. and Gurdon, J. B. (1995). Expression cloing of Siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis. Cell 81: 85-94

Li, J., Chen, X., Ding, X., Cheng, Y., Zhao, B., Lai, Z. C., Al Hezaimi, K., Hakem, R., Guan, K. L. and Wang, C. Y. (2013). LATS2 suppresses oncogenic Wnt signaling by disrupting beta-catenin/BCL9 interaction. Cell Rep 5: 1650-1663. PubMed ID: 24360964; Graphical Abstract

Li, W., et al. (2003). Squamous cell carcinoma and mammary abscess formation through squamous metaplasia in Smad4/Dpc4 conditional knockout mice. Development 130: 6143-6153. 14597578

Li, X., et al. (2001). Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus. EMBO J. 20: 4122-4131. 11483515

Lin, R., Hill, R. J. and Priess, J. R. (1998). POP-1 and anterior-posterior fate decisions in C. elegans embryos. Cell 92: 229-239. PubMed Citation: 9458047

Lickert, H., et al. (2002). Formation of multiple hearts in mice following deletion of ß-catenin in the embryonic endoderm. Dev. Cell 3: 171-181. 12194849

Lickert, H., et al. (2005). Dissecting Wnt/ß-catenin signaling during gastrulation using RNA interference in mouse embryos. Development 132: 2599-2609. 15857914

Lin, L., et al. (2007). β-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis. Proc. Natl. Acad. Sci. 104(22): 9313-8. Medline abstract: 17519333

Lin, S.-Y., et al. (2000). ß-catenin, a novel prognostic marker for breast cancer: Its role in cyclin D1 expression and cancer progression. Proc. Natl. Acad. Sci. 97: 4262-4266. 10759547

Linask, K. K., Knudsen, K. A. and Gui, Y. H. (1997). N-cadherin-catenin interaction: necessary component of cardiac cell compartmentalization during early vertebrate heart development. Dev. Biol. 185(2): 148-164

Liu, C., et al. (1999). beta-trcp couples beta-catenin phosphorylation-degradation and regulates xenopus axis formation. Proc. Natl. Acad. Sci. 96(11): 6273-8

Liu, C., et al. (2002). Control of ß-Catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 108: 837-847. 11955436

Liu, J., et al. (2001). Siah-1 mediates a novel ß-Catenin degradation pathway linking p53 to the Adenomatous polyposis coli protein. Mol. Cell 7: 927-936. 11389840

Liu, J. and Farmer, S. R. (2004). Regulating the balance between peroxisome proliferator-activated receptor gamma and ß-catenin signaling during adipogenesis. A glycogen synthase kinase 3ß phosphorylation-defective mutant of ß-catenin inhibits expression of a subset of adipogenic genes. J Biol Chem. 279(43): 45020-7. 15308623

Liu, J., et al. (2006). The third 20 amino acid repeat is the tightest binding site of APC for ß-catenin. J. Mol. Biol. 360(1): 133-44. 16753179

Llimargas, M. (2000). wingless and its signalling pathway have common and separable functions during tracheal development. Development 127: 4407-4417

López-Schier, H. and St Johnston, D. (2002). Drosophila Nicastrin is essential for the intramembranous cleavage of Notch. Dev. Cell 2: 79-89. 11782316

Loureiro, J. and Peifer, M. (1998). Roles of Armadillo, a Drosophila catenin, during central nervous system development. Curr. Biol. 8(11): 622-32

Loureiro, J. J., et al. (2001). Activated Armadillo/ß-Catenin does not play a general role in cell migration and process extension in Drosophila. Dev. Bio. 235: 33-44. 11412025

Lowry, W. E., et al. (2005). Defining the impact of ß-catenin/Tcf transactivation on epithelial stem cells. Genes Dev. 19: 1596-1611. 15961525

Lu, Q., et al. (1999). delta-catenin, an adhesive junction-associated protein which promotes cell scattering. J. Cell Biol. 144(3): 519-532. PubMed Citation: 9971746

Lyu, J. and Joo, C.-K. (2004). Wnt signaling enhances FGF2-triggered lens fiber cell differentiation. Development 131: 1813-1824. 15084465

Mao, Y., et al. (2009). Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell 136(6): 1017-31. PubMed Citation: 19303846

Marikawa, Y., Li, Y. and Elinson, R. P. (1997). Dorsal determinants in the Xenopus egg are firmly associated with the vegetal cortex and behave like activators of the wnt pathway. Dev. Biol. 191(1): 69-79. PubMed Citation: 9356172

Markiewicz, E., et al. (2006). The inner nuclear membrane protein emerin regulates ß-catenin activity by restricting its accumulation in the nucleus. EMBO J. 25(14): 3275-85. 16858403

Marygold, S. J. and Vincent, J.-P. (2003). Armadillo levels are reduced during mitosis in Drosophila. Mech. Dev. 120: 157-165. 12559488

Matsumine, A., et al. (1996). Binding of APC to the human homolog of the Drosophila Discs Large tumor suppressor protein. Science 272: 1020-1023. PubMed Citation: 8638125

Matsuzawa, S.-I. and Reed, J. C. (2001). Siah-1, SIP, and Ebi collaborate in a novel pathway for ß-catenin degradation linked to p53 responses. Mol. Cell 7: 915-926. 11389839

McCartney, B. M., et al. (1999). Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis. J. Cell Biol. 146: 1303-1318. PubMed Citation: 10491393

Merriam, J. M., Rubenstein, A. B. and Klykowsky, M. W. (1997). Cytoplasmically anchored plakoglobin induces a WNT-like phenotype in Xenopus. Dev. Biol. 185: 67-81

McCartney, B. M., et al. (1999). Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis. J. Cell Biol. 146(6): 1303-18. PubMed Citation: 10491393

McCartney, B. M., McEwen, D. G., Grevengoed, E., Maddox, P., Bejsovec, A. and Peifer, M. (2001). Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin. Nat. Cell Biol. 3: 933-938. PubMed Citation: 11584277

McClay, D. R., et al. (2000). A micromere induction signal is activated by beta-catenin and acts through Notch to initiate specification of secondary mesenchyme cells in the sea urchin embryo. Development 127: 5113-5122

McEwen, D. G., Cox, R. J. and Peifer, M. (2000). The canonical Wg and JNK signaling cascades collaborate to promote both dorsal closure and ventral patterning. Development 127: 3607-3617. PubMed Citation: 10903184

McLin, V. A., Rankin, S. A. and Zorn, A. M. (2007). Repression of Wnt/β-catenin signaling in the anterior endoderm is essential for liver and pancreas development. Development 134: 2207-2217. Medline abstract: 17507400

Miller, J. R. and Moon, R. T. (1997). Analysis of the signaling activities of localization mutants of beta-catenin during axis specification in Xenopus. J. Cell Biol. 139: 229-243

Mirkovic, I., et al. (2002). Drosophila nemo is an essential gene involved in the regulation of programmed cell death. Mech. Dev. 119: 9-20. 12385750

Mirkovic, I., et al. (2011). Nemo kinase phosphorylates β-catenin to promote ommatidial rotation and connects core PCP factors to E-cadherin-β-catenin. Nat. Struct. Mol. Biol. 18(6): 665-72. PubMed Citation: 21552260

Mizumoto, K. and Sawa, H. (2007). Cortical β-catenin and APC regulate asymmetric nuclear β-catenin localization during asymmetric cell division in C. elegans. Dev. Cell 12(2): 287-99. Medline abstract: 17276345

Miyawaki, K., et al. (2004). Involvement of Wingless/Armadillo signaling in the posterior sequential segmentation in the cricket, Gryllus bimaculatus (Orthoptera), as revealed by RNAi analysis. Mech. Dev. 121: 119-130. 15037314

Mohan, M., et al. (2010). Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom). Genes Dev. 24(6): 574-89. PubMed Citation: 20203130

Molenaar, M., et al. (1996). XTcf-3 transcription factor mediates ß-catenin-induced axis formation in Xenopus embryos. Cell 86: 391-399. PubMed Citation: 8756721

Morel, V. and Arias, A. M. (2004). Armadillo/ß-catenin-dependent Wnt signalling is required for the polarisation of epidermal cells during dorsal closure in Drosophila. Development 131: 3273-3283. 15226252

Morkel, M., et al. (2003). ß-Catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation. Development 130: 6283-6294. 14623818

Mosimann, C., Hausmann, G. and Basler, K. (2006). Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with β-catenin/Armadillo. Cell 125(2): 327-41. Medline abstract: 16630820

Mosimann, C., Hausmann, G. and Basler, K. (2009). Beta-catenin hits chromatin: regulation of Wnt target gene activation. Nat. Rev. Mol. Cell Biol. 10: 276-286. PubMed Citation: 19305417

Müller, H.-A. and Wieschaus, E. (1996). armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila. J. Cell Biol. 134: 149-163

Muller, T., et al. (1999). Phosphorylation and free pool of beta-catenin are regulated by tyrosine kinases and tyrosine phosphatases during epithelial cell migration. J. Biol. Chem. 274(15): 10173-83

Moon, R. T., Brown, J. D. and Torres, M. (1997). WNTs modulate cell fate and behavior during vertebrate development. Trends Genet. 13: 157-163

Mosimann, C., Hausmann, G. and Basler, K. (2006). Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with β-catenin/Armadillo. Cell 125(2): 327-41. 16630820

Muñoz-Descalzo, S., et al. (2011). Modulation of the ligand-independent traffic of Notch by Axin and Apc contributes to the activation of Armadillo in Drosophila. Development 138: 1501-1506. PubMed Citation: 21389052

Murase, S., Mosser, E. and Schuman, E. M. (2002). Depolarization drives ß-Catenin into neuronal spines promoting changes in synaptic structure and function. Neuron 35(1): 91-105. 12123611

Murayama, M., et al. (1998). Direct association of presenilin-1 with beta-catenin. FEBS Lett. 433(1-2): 73-7

Murray, M. J., Davidson, C. M., Hayward, N. M. and Brand, A. H. (2006). The Fes/Fer non-receptor tyrosine kinase cooperates with Src42A to regulate dorsal closure in Drosophila. Development 133(16): 3063-73. 16831834

Murtaugh, L. C., Law, A. C., Dor, Y. and Melton, D. A. (2005). β-Catenin is essential for pancreatic acinar but not islet development. Development 132: 4663-4674. 16192304

Continued: armadillo References part 2/2

armadillo: Biological Overview | Evolutionary Homologs | Regulation | Protein Interactions | Developmental Biology | Effects of Mutation

Home page: The Interactive Fly © 1995, 1996 Thomas B. Brody, Ph.D.

The Interactive Fly resides on the
Society for Developmental Biology's Web server.