REFERENCES (part 1/3)

Abu-Shaar, M. and Mann, R. S. (1998). Generation of multiple antagonistic domains along the proximodistal axis during Drosophila leg development. Development 125(19): 3821-3830. PubMed Citation: 9729490

Adams, K. A., et al. (2000). The transcription factor Lmx1b maintains Wnt1 expression within the isthmic organizer. Development 127: 1857-1867. PubMed Citation: 10751174

Adell, T., et al. (2009). Smed-Evi/Wntless is required for β-catenin-dependent and -independent processes during planarian regeneration. Development 136: 905-910. PubMed Citation: 19211673

Agathocleous, M., et al. (2009). A directional Wnt/beta-catenin-Sox2-proneural pathway regulates the transition from proliferation to differentiation in the Xenopus retina. Development 136(19): 3289-99. PubMed Citation: 19736324

Alexandre, C., Jacinto, A., and Ingham, P. W. (1996). Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the Cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins. Genes Dev. 10: 2003-13. 8769644

Alexandre, C., Lecourtois, M. and Vincent, J.-P. (1999). Wingless and Hedgehog pattern Drosophila denticle belts by regulating the production of short-range signals. Development 126: 5689-5698. PubMed Citation: 10572045

Alexandre, C., Baena-Lopez, A. and Vincent, J. P. (2014). Patterning and growth control by membrane-tethered Wingless. Nature 505: 180-185. PubMed ID: 24390349

Aman, A. and Piotrowski, T. (2008). Wnt/beta-catenin and Fgf signaling control collective cell migration by restricting chemokine receptor expression. Dev. Cell 15(5): 749-61. PubMed Citation: 19000839

Amin, A., Li, Y. and Finkelstein, R. (1999). Hedgehog activates the EGF receptor pathway during Drosophila head development. Development 126(12): 2623-2630. PubMed Citation: 10331974

Amoyel, M., Cheng, Y.-C., Jiang, Y.-J. and Wilkinson, D. G. (2005). Wnt1 regulates neurogenesis and mediates lateral inhibition of boundary cell specification in the zebrafish hindbrain. Development 132: 775-785. 15659486

Anakwe, K., et al. (2003). Wnt signalling regulates myogenic differentiation in the developing avian wing. Development 130: 3503-3514. 12810597

Andl, T., et al. (2002). WNT signals are required for the initiation of hair follicle development. Dev. Cell Vol 2: 643-653. 12015971

Ataman, B., Ashley, J., Gorczyca, M., Ramachandran, P., Fouquet, W., Sigrist, S. J. and Budnik, V. (2008). Rapid activity-dependent modifications in synaptic structure and function require bidirectional Wnt signaling. Neuron 57: 705-718. PubMed Citation: 18341991

Aulehla, A., et al. (2003). Wnt3a plays a major role in the segmentation clock controlling somitogenesis. Developmental Cell 4: 395-406. 12636920

Avanesov, A., Honeyager, S. M., Malicki, J. and Blair, S. S. (2012). The role of glypicans in Wnt inhibitory factor-1 activity and the structural basis of Wif1's effects on Wnt and Hedgehog signaling. PLoS Genet. 8(2): e1002503. PubMed Citation: 22383891

Axelrod, J. D., Matsuno, K., Artavanis Tsakonas, S., and Perrimon, N. (1996). Interaction between Wingless and Notch signaling pathways mediated by Dishevelled. Science 271: 1826-1832. 8596950

Axelrod, J. D., et al. (1998). Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes Dev. 12(16): 2610-2622. PubMed Citation: 9716412

Ayyar S., et al. (2007). NF-kappaB/Rel-mediated regulation of the neural fate in Drosophila. PLoS ONE 2: e1178. PubMed Citation: 18000549

Ayyar, S., et al. (2010). An arthropod cis-regulatory element functioning in sensory organ precursor development dates back to the Cambrian. BMC Biol. 8: 127. PubMed Citation: 20868489

Azpiazu, N., et al. (1996). Segmentation and specification of the Drosophila mesoderm. Genes Dev. 10: 3183-94. 8985186

Backman, M., et al. (2004). Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon. Dev. Biol. 279: 155-168. 15708565

Baeg, G.-H., et al. (2001). Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless. Development 128: 87-94. 11092814

Baeg, G. H., Selva, E. M., Goodman, R. M., Dasgupta, R. and Perrimon, N. (2004). The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycan receptors. Dev. Biol. 276(1): 89-100. 15531366

Baena-López, L. A. and García-Bellido. A. (2003). Genetic requirements of vestigial in the regulation of Drosophila wing development. Development 130: 197-208. 12441303

Bajard, L., Morelli, L. G., Ares, S., Pecreaux, J., Julicher, F. and Oates, A. C. (2014). Wnt-regulated dynamics of positional information in zebrafish somitogenesis. Development 141: 1381-1391. PubMed ID: 24595291

Bang, A. G., et al. (1999). Expression of Pax-3 in the lateral neural plate is dependent on a Wnt-mediated signal from posterior nonaxial mesoderm. Dev. Biol. 212(2): 366-80. PubMed Citation: 10433827

Banziger, C., et al. (2006). Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell 125: 509-522. PubMed Citation: 16678095

Baonza, A., Roch, F. and Martin-Blanco, E. (2000). DER signaling restricts the boundaries of the wing field during Drosophila development. Proc. Natl. Acad. Sci. 97: 7331-7335. PubMed Citation: 10860999

Baonza, A. and Freeman, M. (2002). Control of Drosophila eye specification by Wingless signaling. Development 129: 5313-5322. 12403704

Baranski, M., et al. (2000). The dynamic expression pattern of frzb-1 suggests multiple roles in chick development. Dev. Biol. 217: 25-41. PubMed Citation: 10625533

Bate, M. and Rushton, E. (1993). Myogenesis and muscle patterning in Drosophila. C. R. Acad. Sci. III 316: 1047-1061. PubMed Citation: 8076205

Bänziger, C., Soldini, D., Schütt, C., Zipperlen, P., Hausmann, G. and Basler, K. (2006). Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell 125: 509-522. Medline abstract: 16678095

Bartscherer, et al. (2006). Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell 125: 523-533. PubMed Citation: 16678096

Baylies, M. K., Martinez Arias, A. and Bate, M. (1995). wingless is required for the formation of a subset of muscle founder cells during Drosophila embryogenesis. Development 121: 3829-37. 8582292

Bei, Y., et al. (2002). SRC-1 and Wnt signaling act together to specify endoderm and to control cleavage orientation in early C. elegans embryos. Dev. Cell 3: 113-125. 12110172

Bejsovec, A., and Arias, A.M. (1991). Roles of wingless in patterning the larval epidermis of Drosophila. Development 113: 471-85. PubMed Citation: 1782860

Bejsovec, A. and Wieschaus, E. (1993). Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos. Development 119: 501-517. PubMed Citation: 8287799

Bejsovec, A., and Wieschaus, E. (1995). Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface. Genetics 139: 309-20. PubMed Citation: 7705631

Bejsovec, A, and Chao, A. T. (2012). crinkled reveals a new role for Wingless signaling in Drosophila denticle formation. Development 139(4): 690-8. PubMed Citation: 22219350

Belenkaya, T. Y., Han, C., Yan, D., Opoka, R. J., Khodoun, M., Liu, H. and Lin, X. (2004). Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the glypican members of heparan sulfate proteoglycans. Cell 119(2): 231-44. PubMed Citation: 15479640

Belenkaya, T. Y., et al. (2008). The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network. Dev. Cell 14(1): 120-31. PubMed Citation: 18160348

Balmer, S., Dussert, A., Collu, G. M., Benitez, E., Iomini, C. and Mlodzik, M. (2015). Components of Intraflagellar Transport complex A function independently of the cilium to regulate canonical Wnt signaling in Drosophila. Dev Cell 34(6):705-18. PubMed ID: 26364750

Benedyk, M. J., Mullen, J. R. and DiNardo, S. (1994). odd-paired: a zinc finger pair-rule protein required for the timely activation of engrailed and wingless in Drosophila embryos. Genes Dev. 8: 105-17. PubMed Citation: 8288124

Bessa, J. and Casares, F. (2005). Restricted teashirt expression confers eye-specific responsiveness to Dpp and Wg signals during eye specification in Drosophila. Development 132: 5011-5020. PubMed Citation: 16221726

Bhanot, P, et al. (1996). A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 382: 225-230. PubMed Citation: 8717036

Bhanot, P., et al. (1999). Frizzled and DFrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development. Development 126: 4175-4186. PubMed Citation: 10457026

Bhaskar, V. and Courey, A. J. (2002). The MADF-BESS domain factor Dip3 potentiates synergistic activation by Dorsal and Twist. Gene 299(1-2): 173-84. PubMed Citation: 12459265

Bhat, K. M. (1996). The patched signaling pathway mediates repression of gooseberry allowing neuroblast specification by wingless during Drosophila neurogenesis. Development 122: 2921-32. 8787765

Bhat, K. M. and Schedl, P. (1997). Requirement for engrailed and invected genes reveals novel regulatory interactions between engrailed/invected, patched, gooseberry and wingless during Drosophila neurogenesis. Development 124: 1689-1698

Bhat, K. M. (1998). frizzled and frizzled 2 play a partially redundant role in wingless signaling and have similar requirements to Wingless in neurogenesis. Cell 95: 1027-1036

Bhat, K. M., van Beers, E. H. and Bhat, P. (2000). Sloppy paired acts as the downstream target of Wingless in the Drosophila CNS and interaction between sloppy paired and gooseberry inhibits sloppy paired during neurogenesis. Development 127(3): 655-665. 10631185

Bikkavilli, R. K., Feigin, M. E. and Malbon, C. C. (2008). p38 mitogen-activated protein kinase regulates canonical Wnt-beta-catenin signaling by inactivation of GSK3beta. J. Cell Sci. 121(Pt 21): 3598-607. PubMed Citation: 18946023

Bilder, D., Graba, Y. and Scott, M. (1998a). Wnt and TGFbeta signals subdivide the AbdA hox domain during Drosophila mesoderm patterning. Development 125(9): 1781-1790

Bilder, D. and Scott, M. P. (1998b). Hedgehog and Wingless induce metameric pattern in the Drosophila visceral mesoderm. Dev. Biol. 201(1): 43-56

Bilic, J., et al. (2007). Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation. Science 316(5831): 1619-22. PubMed Citation: 17569865

Binari, R. and Perrimon, N. (1994). Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila. Genes Dev 8: 300-12. PubMed Citation: 8314084

Binari, R. C., et al. (1997). Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling. Development 124(13): 2623-2632. PubMed Citation: 9217004

Boldajipour, B., et al. (2008). Control of chemokine-guided cell migration by ligand sequestration. Cell 132(3): 463-73. PubMed Citation: 18267076

Bolognesi, R., Farzana, L., Fischer, T. D. and Brown, S. J. (2008). Multiple Wnt genes are required for segmentation in the short-germ embryo of Tribolium castaneum. Curr. Biol. 18(20): 1624-9. PubMed Citation: 18926702

Bonneaud, N., Savare, J., Berta, P. and Girard, F. (2003). SNCF, a SoxNeuro interacting protein, defines a novel protein family in Drosophila melanogaster. Gene 319: 33-41. Medline abstract: 14597169

Borello, U., et al. (1999). Transplacental delivery of the Wnt antagonist Frzb1 inhibits development of caudal paraxial mesoderm and skeletal myogenesis in mouse embryos. Development 126: 4247-4255

Bornemann, D. J., Duncan, J. E., Staatz, W., Selleck, S. and Warrior, R. (2004). Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways. Development 131(9): 1927-38. 15056609

Borod, E. R. and Heberlein, U. (1998). Mutual regulation of decapentaplegic and hedgehog during the initiation of differentiation in the Drosophila retina. Dev. Biol. 197(2): 187-197. PubMed Citation: 9630745

Borycki, A.-G., Brown, A. M. C. and Emerson, C. P. (2000). Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites. Development 127: 2075-2087. PubMed Citation: 10769232

Bossing, T and Brand, A. H. (2006). Determination of cell fate along the anteroposterior axis of the Drosophila ventral midline. Development 133: 1001-1012. 16467357

Boulianne, G. L. and Trimble, W. S. (1995). Identification of a second homolog of N-ethylmaleimide-sensitive fusion protein that is expressed in the nervous system and secretory tissues of Drosophila. Proc. Natl. Acad. Sci. 92(15): 7095-7099. 7624376

Boyle, M., Bonini, N. and DiNardo, S. (1997). Expression and function of clift in the development of somatic gonadal precursors within the Drosophila mesoderm. Development 124: 971-982. PubMed Citation: 9056773

Bradley, L., et al. (2000). Different activities of the Frizzled-related proteins frzb2 and sizzled2 during Xenopus anteroposterior patterning. Dev. Biol. 227: 118-132. PubMed Citation: 11076681

Bradley, P. L. and Andrew, D. J. (2001). ribbon encodes a novel BTB/POZ protein required for directed cell migration in Drosophila melanogaster. Development 128: 3001-3015. 11532922

Bras-Pereira, C., Bessa, J. and Casares, F. (2006). Odd-skipped genes specify the signaling center that triggers retinogenesis in Drosophila. Development 133(21): 4145-9. PubMed citation: 17021046

Brás-Pereira, C, and Casares, F. (2008). An antennal-specific role for bowl in repressing supernumerary appendage development in Drosophila. Mech. Dev. 125: 809-821. PubMed Citation: 18662773

Braun, M. M., et al. (2003). Wnt signaling is required at distinct stages of development for the induction of the posterior forebrain. Development 130: 5579-5587. 14522868

Brennan, K., et al. (1999). Wingless modulates the effects of dominant negative notch molecules in the developing wing of Drosophila. Dev. Biol. 216(1): 210-29

Brennan, K., Baylies, M. and Martinez Arias, A. (2000). Repression by Notch is required before Wingless signaling during muscle progenitor cell development in Drosophila. Curr. Biol. 9: 707-710

Brennecke, J., Hipfner, D. R., Stark, A., Russell, R. B. and Cohen, S. M. (2003). bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 113: 25-36. 12679032

Briata, P., et al. (2003). The Wnt/ß-Catenin --> Pitx2 pathway controls the turnover of Pitx2 and other unstable mRNAs. Molec. Cell 12: 1201-1211. 14636578

Brisken, C., et al. (2000). Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling. Genes Dev. 14: 650-654

Brunner, E., et al. (1997). pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila. Nature 385: 829-933

Brunner E., et al. (1999). The dominant mutation glazed is a gain-of-function allele of wingless that, similar to loss of APC, interferes with normal eye development. Dev. Biol. 206(2): 178-88. 99143072

Bryja, V., Schulte, G., Rawal, N., Grahn, A. and Arenas, E. (2007). Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. J. Cell Sci. 120(Pt 4): 586-95. PubMed citation: 17244647

Buceta, J., Herranz, H., Canela-Xandri, O., Reigada, R., Sagues, F. and Milan, M. (2007). Robustness and stability of the gene regulatory network involved in DV boundary formation in the Drosophila wing. PLoS ONE 2: e602. PubMed Citation: 17622347

Buckles, G. R., et al. (2004). Combinatorial Wnt control of zebrafish midbrain-hindbrain boundary formation. Mech. Dev. 121: 437-447. 15147762

Buescher, M., Svendsen, P. C., Tio, M., Miskolczi-McCallum, C., Tear, G., Brook, W. J. and Chia, W. (2004). Drosophila T box proteins break the symmetry of hedgehog-dependent activation of wingless. Curr. Biol. 14(19): 1694-702. 15458640

Buescher, M., Tio, M., Tear, G., Overton, P. M., Brook, W. J. and Chia, W. (2006). Functions of the segment polarity genes midline and H15 in Drosophila melanogaster neurogenesis. Dev. Biol. 292(2): 418-29. 16499900

Bulfone, A., et al. (1993). Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries. J Neurosci 13: 3155-72

Bullock, S. L., et al. (2004). Differential cytoplasmic mRNA localisation adjusts pair-rule transcription factor activity to cytoarchitecture in dipteran evolution. Development 131: 4251-4261. 15280214

Buratovich, M. A., Phillips, R. G. and Whittle, J. R. (1997). Genetic relationships between the mutations spade and Sternopleural and the wingless gene in Drosophila development. Dev. Biol. 185(2): 244-260

Buratovich, M. A., et al. (2000). DWnt-4 and Wingless have distinct activities in the Drosophila dorsal epidermis. Dev. Genes Evol. 210: 111-119

Burstyn-Cohen, T., et al. (2004). Canonical Wnt activity regulates trunk neural crest delamination linking BMP/noggin signaling with G1/S transition. Development 131: 5327-5339. 15456730

Buttitta, L., et al. (2003). Microarray analysis of somitogenesis reveals novel targets of different WNT signaling pathways in the somitic mesoderm. Dev. Biol. 258: 91-104. 12781685

Cadigan, K. M., Grossniklaus, U. and Gehring, W, J. (1994). Localized expression of sloppy paired protein maintains the polarity of Drosophila parasegments. Genes Dev 8: 899-913

Cadigan, K. M. and Nusse, R. (1996). wingless signaling in the Drosophila eye and embryonic epidermis. Development 122: 2801-12. 8787754

Cadigan, K. M., et al. (1998). Wingless repression of Drosophila frizzled 2 expression shapes the wingless morphogen gradient in the wing. Cell 93: 767-777

Cadigan, K. M., Jou, A. D. and Nusse, R. (2002). Wingless blocks bristle formation and morphogenetic furrow progression in the eye through repression of Daughterless. Development 129: 3393-3402. 12091309

Caldwell, P. E., Walkiewicz, M. and Stern, M. (2005). Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release. Curr. Biol. 15: 1785-1795. PubMed Citation: 16182526

Calleja, M., et al. (1996). Visualization of gene expression in living adult Drosophila. Science 274: 252-256

Cambier, L., Plate, M., Sucov, H. M. and Pashmforoush, M. (2014). Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3. Development 141: 2959-2971. PubMed ID: 25053429

Campbell, G., Weaver, T. and Tomlinson, A. (1993). Axis specification in the developing Drosophila appendage: The role of wingless, decapentaplegtic and the homeobox gene aristaless. Cell 74: 1113-1123

Campbell, G. and Tomlinson, A. (1998). The roles of the homeobox genes aristaless and Distal-less in patterning the legs and wings of Drosophila. Development 125(22): 4483-4493. 9778507

Campbell, G. (2002). Distalization of the Drosophila leg by graded EGF-receptor activity. Nature 418: 781-785. 12181568

Capdevila, J., et al. (1994). Subcellular localization of the segment polarity protein ptc suggests an interaction with the wingless reception complex in Drosophila embryos. Development 120: 987-998. 7600973

Capdevila, J., Tabin, C. and Johnson, R. L. (1998). Control of dorsoventral somite patterning by Wnt-1 and beta-Catenin. Dev. Biol. 193(2): 182-194

Carl, M., et al. (2007). Wnt/Axin1/beta-catenin signaling regulates asymmetric nodal activation, elaboration, and concordance of CNS asymmetries. Neuron 55(3): 393-405. PubMed citation: 17678853

Caronia-Brown, G., Yoshida, M., Gulden, F., Assimacopoulos, S. and Grove, E. A. (2014). The cortical hem regulates the size and patterning of neocortex. Development 141: 2855-2865. PubMed ID: 24948604

Carroll, T. J., Park, J. S., Hayashi, S., Majumdar, A. and McMahon, A. P. (2005). Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the Mammalian urogenital system. Dev Cell 9(2): 283-92. 16054034

Casares, F. and Mann, R. S. (2000). A dual role for homothorax in inhibiting wing blade development and specifying proximal wing identities in Drosophila. Development 127: 1499-1508

Caviglia, S. and Luschnig, S. (2013). The ETS domain transcriptional repressor Anterior open inhibits MAP kinase and Wingless signaling to couple tracheal cell fate with branch identity. Development 140: 1240-1249. PubMed ID: 23444354

Cavodeassi, F., et al. (1999). Compartments and organizing boundaries in the Drosophila eye: the role of the homeodomain Iroquois proteins. Development 126: 4933-4942

Cavodeassi, F., et al. (2005). Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/ß-Catenin pathway. Neuron 47: 43-56. 15996547

Cavallo, R. A., et al. (1998). Drosophila Tcf and Groucho interact to repress Wingless signalling activity. Nature 395(6702): 604-8

Cha, K. B., et al. (2004). WNT5A signaling affects pituitary gland shape. Mech. Dev. 121: 183-194. 15037319

Cha, S.-W., et al. (2008). Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation. Development 135: 3719-3729. PubMed Citation: 18927149

Chang, C. and Hemmati-Brivanlou, A. (1998). Neural crest induction by Xwnt7B in Xenopus. Dev. Biol. 194(1): 129-134

Chanut, R. and Heberlein, U. (1997). Role of decapentaplegic in initiation and progression of the morphogenetic furrow in the developing Drosophila retina Development 124: 559-567. 9053331

Chao, A. T., Jones, W. M. and Bejsovec, A. (2007). The HMG-box transcription factor SoxNeuro acts with Tcf to control Wg/Wnt signaling activity. Development 134(5): 989-97. Medline abstract: 17267442

Chen, E. H. and Baker. B. S. (1997). Compartmental organization of the Drosophila genital imaginal discs. Development 124: 205-218. 9006081

Chen, Y., et al. (1998). A genetic screen for modifiers of Drosophila decapentaplegic signaling identifies mutations in punt, Mothers against dpp and the BMP-7 homologue, 60A. Development 125(9): 1759-1768. 9521913

Chesnutt, C., et al. (2004). Coordinate regulation of neural tube patterning and proliferation by TGFβ and WNT activity. Dev. Biol. 274: 334-347. 15385163

Chiang, A., et al. (2009). Neuronal activity and Wnt signaling act through Gsk3-β to regulate axonal integrity in mature Drosophila olfactory sensory neurons. Development 136: 1273-1282. PubMed Citation: 19304886

Chihara, T. and Hayashi, S. (2000). Control of tracheal tubulogenesis by Wingless signaling. Development 127: 4433-4442. PubMed Citation: 11003842

Cho, K.-O., et al. (2000). Novel signaling from the peripodial membrane Is essential for eye disc patterning in Drosophila. Cell 103: 331-342. PubMed Citation: 11057905

Cho, S. H. and Cepko, C. L. (2006). Wnt2b/β-catenin-mediated canonical Wnt signaling determines the peripheral fates of the chick eye. Development 133(16): 3167-77. 16854977

Choe, C. P. and Brown, S. J. (2007). Evolutionary flexibility of pair-rule patterning revealed by functional analysis of secondary pair-rule genes, paired and sloppy-paired in the short-germ insect, Tribolium castaneum. Dev. Biol. 302(1): 281-94. PubMed citation: 17054935

Choi, S.-C. and Han, J.-K. (2002). Xenopus Cdc42 regulates convergent extension movements during gastrulation through Wnt/Ca2+ signaling pathway. Dev. Biol. 244: 342-357. 11944942

Chu, E. Y., et al. (2004). Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis. Development 131: 4819-4829. 15342465

Chu-LaGraff, Q. and Doe, C. Q. (1993). Neuroblast specification and formation regulated by wingless in the Drosophila CNS. Science 261: 1594-7

Cline, H. and Haas, K. (2008). The regulation of dendritic arbor development and plasticity by glutamatergic synaptic input: a review of the synaptotrophic hypothesis. J. Physiol. 586: 1509-1517. PubMed Citation: 18202093

Cohen, B., Simcox, A.A. and Cohen, S.M. (1993). Allocation of the thoracic imaginal primordia in the Drosophila embryo. Development 117: 597-608

Couso, J. P., Bishop, S. A., and Martinez Arias, A. (1994). The wingless signalling pathway and the patterning of the wing margin in Drosophila. Development 120: 621-36

Collavin, L. and Kirschner, M. W. (2003). The secreted Frizzled-related protein Sizzled functions as a negative feedback regulator of extreme ventral mesoderm. Development 130: 805-816. 12506010

Colombani, J., Bianchini, L., Layalle, S., Pondeville, E., Dauphin-Villemant, C., Antoniewski, C., Carre, C., Noselli, S. and Leopold, P. (2005). Antagonistic actions of ecdysone and insulins determine final size in Drosophila. Science 310: 667-670. PubMed Citation: 16179433

Colosimo, P. F. and Tolwinski, N. S. (2006). Wnt, Hedgehog and junctional Armadillo/beta-catenin establish planar polarity in the Drosophila embryo. PLoS ONE 1:e9. PubMed citation: 17183721

Constantine-Paton, M. and Cline, H. T. (1998). LTP and activity-dependent synaptogenesis: the more alike they are, the more different they become. Curr. Opin. Neurobiol. 8: 139-148. PubMed Citation: 9568401

Cordero, J. B., Stefanatos, R. K., Myant, K., Vidal, M. and Sansom, O. J. (2012). Non-autonomous crosstalk between the Jak/Stat and Egfr pathways mediates Apc1-driven intestinal stem cell hyperplasia in the Drosophila adult midgut. Development 139: 4524-4535. PubMed ID: 23172913

Coudreuse, D. Y., et al. (2006). Wnt gradient formation requires retromer function in Wnt-producing cells. Science 312: 921-924. PubMed Citation: 16645052

Coudreuse, D. and Korswagen, H. C. (2007). The making of Wnt: new insights into Wnt maturation, sorting and secretion. Development 134: 3-12. PubMed Citation: 17138665

Cong, F., Schweizer, L. and Varmus, H. (2004). Wnt signals across the plasma membrane to activate the ß-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP. Development 131: 5103-5115. 15459103

Cordero, J., Jassim, O., Bao, S. and Cagan, R. (2004). A role for wingless in an early pupal cell death event that contributes to patterning the Drosophila eye. Mech. Dev. 121: 1523-1530. 15511643

Cordero, J. B., Stefanatos, R. K., Scopelliti, A., Vidal, M. and Sansom, O. J. (2012). Inducible progenitor-derived Wingless regulates adult midgut regeneration in Drosophila. EMBO J 31: 3901-3917. PubMed ID: 22948071

Coudreuse, D. Y., Roel, G., Betist, M. C., Destree, O. and Korswagen, H. C. (2006). Wnt gradient formation requires retromer function in Wnt-producing cells. Science 312: 921-924. PubMed citation: 16645052

Cox, V. T. and Baylies, M. K. (2005). Specification of individual Slouch muscle progenitors in Drosophila requires sequential Wingless signaling Development 132: 713-724. 1564732

Crease, D. J., Dyson, S. and Gurdon, J. B. (1998). Cooperation between the activin and wnt pathways in the spatial control of organizer gene expression. Proc. Natl. Acad. Sci. 95(8): 4398-4403

Crozatier, M. and Vincent, V. (1999a). Requirement for the Drosophila COE transcription factor Collier in formation of an embryonic muscle: transcriptional response to Notch signalling. Development 126: 1495-1504

Crozatier, M., et al. (1999b). Head versus trunk patterning in the Drosophila embryo; collier requirement for formation of the intercalary segment. Development 126: 4385-4394

Culi, J. and Modolell, J. (1998). Proneural gene self-stimulation in neural precursors: an essential mechanism for sense organ development that is regulated by Notch signaling. Genes Dev. 12: 2036-2047. PubMed Citation: 9649507

Cunliffe, V. and Smith, J. C. (1994). Specification of mesodermal pattern in Xenopus laevis by interactions between Brachyury, noggin and Xwnt-8. EMBO J 13: 349-59

Cygan, J. A., Johnson, R. L. and McMahon, A. P. (1997). Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants. Development 124(24): 5021-5032

Dabdoub, A., et al. (2003). Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea. Development 130: 2375-2384. 12702652

Dacks A. M., et al. (2009). Serotonin modulates olfactory processing in the antennal lobe of Drosophila. J. Neurogenet. 23. 366-377. PubMed Citation: 19863268

D'Alessio, M. D. and Frasch, M. (1996). msh may play a conserved role in dorsoventral patterning of the neuroectoderm and mesoderm. Mech. Dev. 58: 217-231

Damen, W. G. M. (2002). Parasegmental organization of the spider embryo implies that the parasegment is an evolutionary conserved entity in arthropod embryogenesis. Development 129: 1239-1250. 11874919

Danesin, C., et al. (2009). Integration of telencephalic Wnt and Hedgehog signaling center activities by Foxg1. Dev. Cell 16: 576-587. PubMed Citation: 19386266

Dani, N., Nahm, M., Lee, S. and Broadie, K. (2012). A targeted glycan-related gene screen reveals heparan sulfate proteoglycan sulfation regulates WNT and BMP trans-synaptic signaling. PLoS Genet 8: e1003031. PubMed ID: 23144627

Danielian, P. S., McMahon, A. P. (1996). Engrailed-1 as a target of the WNT-1 signalling pathway in the vertebrate midbrain development. Nature 383: 332-334. PubMed Citation: 8848044

Darken, R. S. and Wilson, P. A. (2001). Axis induction by Wnt signaling: target promoter responsiveness regulates competence. Dev. Bio. 234: 42-54. 11356018

DasGupta, R., Kaykas, A., Moon, R. T. and Perrimon, N. (2005). Functional genomic analysis of the Wnt-Wingless signaling pathway. Science 308: 826-833. 15817814

Davidson, E. H., et al. (2002). A provisional regulatory gene network for specification of endomesoderm in the sea urchin embryo. Dev. Biol. 246: 162-190. 12027441

Davidson, G., Wu, W., Shen, J., Bilic, J., Fenger, U., Stannek, P., Glinka, A. and Niehrs, C. (2005). Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction. Nature 438: 867-872. PubMed ID: 16341016

Dear, M. L., Dani, N., Parkinson, W., Zhou, S. and Broadie, K. (2015). Two matrix metalloproteinase classes reciprocally regulate synaptogenesis. Development 143(1):75-87. PubMed ID: 26603384

Dearborn, R. and Kunes, S. (2004). An axon scaffold induced by retinal axons directs glia to destinations in the Drosophila optic lobe. Development 131: 2291-2303. 15102705

Deb, D. K., Tanaka-Matakatsu, M., Jones, L., Richardson, H. E. and Du, W. (2008). Wingless signaling directly regulates cyclin E expression in proliferating embryonic PNS precursor cells. Mech. Dev. 125(9-10): 857-64. PubMed Citation: 18606221

de Celis, J. F., Garcia-Bellido, A. and Bray, S. J. (1996). Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc. Development 122: 359-369. PubMed Citation: 8565848

de Celis, J. F. and Bray. S. (1997). Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing. Development 124(17): 3241-3251

de Celis, J. F., Barrio, R. and Kafatos, F. C. (1999). Regulation of the spalt/spalt-related gene complex and its function during sensory organ development in the Drosophila thorax. Development 126(12): 2653-2662

Deardorff, M. A., et al. (1998). Frizzled-8 is expressed in the Spemann organizer and plays a role in early morphogenesis. Development 125(14): 2687-2700.

Deardorff, M. A., et al. (2001). A role for frizzled 3 in neural crest development. Development 128: 3655-3663. 11585792

De Langhe, S. P., et al. (2005). Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung. Dev. Biol. 277(2): 316-31. 15617677

Delanoue, R. and Davis, I. (2005). Dynein anchors its mRNA cargo after apical transport in the Drosophila blastoderm embryo. Cell 122: 97-106. 16009136

Delaunay, D., Cortay, V., Patti, D., Knoblauch, K. and Dehay, C. (2014). Mitotic spindle asymmetry: a Wnt/PCP-regulated mechanism generating asymmetrical division in cortical precursors. Cell Rep 6: 400-414. PubMed ID: 24412369

Deshpande, N. Dittrich, R., Technau, G. M. and Urban, J. (2001). Successive specification of Drosophila neuroblasts NB 6-4 and NB 7-3 depends on interaction of the segment polarity genes wingless, gooseberry and naked cuticle. Development 128: 3253-3261. 11546742

Devgan, V., et al. (2005). p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes Dev. 19: 1485-1495. 15964998

Diaz-Benjumea, F. J. and Cohen, S. M. (1994). wingless acts through the shaggy/zeste-white 3 kinase to direct dorsal-ventral axis formation in the Drosophila leg. Development 120: 1661-1670. PubMed Citation: 8050372

Diaz-Benjumea, F. J. and Cohen, S. M. (1995). Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing. Development 121: 4215-25. PubMed Citation: 8575321

Dichtel-Danjoy, M. L., Caldeira, J. and Casares, F. (2009). SoxF is part of a novel negative-feedback loop in the wingless pathway that controls proliferation in the Drosophila wing disc. Development 136(5): 761-9. PubMed Citation: 19176582

Dichtel-Danjoy, M. L., et al. (2012). Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation. Cell Death Differ. doi: 10.1038/cdd.2012.100. PubMed Citation: 22898807

Dickinson, M. E., Krumlauf, R. and McMahon, A. P. (1994). Evidence for a mitogenic effect of Wnt-1 in the developing mammalian central nervous system. Development 120(6): 1453-71. PubMed Citation: 8050356

Dierick, H. A. and Bejsovec, A. (1998). Functional analysis of Wingless reveals a link between intercellular ligand transport and dorsal-cell-specific signaling. Development 125: 4729-4738. 9806921

Ding, X, Hausen, P. and Steinbeisser, H. (1998). Pre-MBT patterning of early gene regulation in Xenopus: the role of the cortical rotation and mesoderm induction. Mech. Dev. 70: 15-24

Dejima, K., Kang, S., Mitani, S., Cosman, P. C. and Chisholm, A. D. (2014). Syndecan defines precise spindle orientation by modulating Wnt signaling in C. elegans. Development 141: 4354-4365. PubMed ID: 25344071

Domingos, P. M., et al. (2001). The Wnt/ß-Catenin pathway posteriorizes neural tissue in Xenopus by an indirect mechanism requiring FGF signaling. Dev. Biol. 239: 148-160. PubMed ID: 11784025

Dominguez, I. and Green, J. B. A. (2000). Dorsal downregulation of GSK3beta by a non-Wnt-like mechanism is an early molecular consequence of cortical rotation in early Xenopus embryos. Development 127: 861-868. 10648244

Dorsky, R. I., Moon, R. T. and Raible, D. W. (1998). Control of neural crest cell fate by the Wnt signalling pathway. Nature 396(6709): 370-3

Dréan, B. S.-Le, et al. (1998). Dynamic changes in the functions of Odd-skipped during early Drosophila embryogenesis. Development 125: 4851-4861. 9806933

Dreier, L., Burbea, M. and Kaplan, J. M. (2005). LIN-23-mediated degradation of beta-catenin regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans, Neuron 46: 51-64. PubMed citation: 15820693

Duan, H., Skeath, J. B. and Nguyen, H. T. (2001). Drosophila Lame duck, a novel member of the Gli superfamily, acts as a key regulator of myogenesis by controlling fusion-competent myoblast development. Development 128: 4489-4500. 11714674

Dubois, L., et al. (2001). Regulated endocytic routing modulates Wingless signaling in Drosophila embryos. Cell 105: 613-624. 11389831

Duman-Scheel, M., et al. (1997). Genetic separation of the neural and cuticular patterning functions of gooseberry. Development 124(15): 2855-2865

Duman-Scheel, M., Johnston, L. A. and Du, W. (2004). Repression of dMyc expression by Wingless promotes Rbf-induced G1 arrest in the presumptive Drosophila wing margin. Proc. Natl. Acad. Sci. 101(11): 3857-62. 15001704

Duong, H. A., et al. (2008). Transformation of eye to antenna by misexpression of a single gene. Mech. Dev. 125: 130-141. PubMed Citation: 18037276

Dyer, C., Blanc, E., Hanisch, A., Roehl, H., Otto, G. W., Yu, T., Basson, M. A. and Knight, R. (2014). A bi-modal function of Wnt signalling directs an FGF activity gradient to spatially regulate neuronal differentiation in the midbrain. Development 141: 63-72. PubMed ID: 24284206

Eisenberg, C. A., Gourdie, R. G. and Eisenberg, L. M. (1997). Wnt-11 is expressed in early avian mesoderm and required for the differentiation of the quail mesoderm cell line QCE-6. Development 124: 525-536

Eivers E., et al. (2009). Mad is required for wingless signaling in wing development and segment patterning in Drosophila. PLoS ONE 4: e6543. PubMed Citation: 19657393

Ekas, L. A., et al. (2006). JAK/STAT signaling promotes regional specification by negatively regulating wingless expression in Drosophila. Development 133: 4721-4729. Medline abstract: 17079268

Eldar, A., et al. (2003). Self-enhanced ligand degradation underlies robustness of morphogen gradients. Dev. Cell 5: 635-646. 14536064

Eldon, E., et al. (1994). The Drosophila 18 wheeler is required for morphogenesis and has striking similarities to Toll. Development 120 (4): 885-899. PubMed Citation: 7600965

Elkouby, Y. M., et al. (2010). Mesodermal Wnt signaling organizes the neural plate via Meis3. Development 137(9): 1531-41. PubMed Citation: 20356957

Ellies, D. L., et al. (2000). The WNT antagonist cSFRP2 modulates programmed cell death in the developing hindbrain. Development 127: 5285-5295. 11076751

Enomoto-Iwamoto, M., et al. (2002). The Wnt antagonist Frzb-1 regulates chondrocyte maturation and long bone development during limb skeletogenesis. Dev. Bio. 251: 142-156. 12413904

Enshell-Seijffers, D., et al. (2010). β-catenin activity in the dermal papilla regulates morphogenesis and regeneration of hair. Dev. Cell 18: 633-642. PubMed Citation: 20439431

Eresh, S., et al. (1997). A CREB-binding site as a target for decapentaplegic signalling during Drosophila endoderm induction. EMBO J. 16: 2014-22

Erter, C. E., et al. (2001). Wnt8 is required in lateral mesendodermal precursors for neural posteriorization in vivo. Development 128: 3571-3583. 11566861

Espinosa, J. S., Wheeler, D. G., Tsien, R. W. and Luo, L. (2009). Uncoupling dendrite growth and patterning: single-cell knockout analysis of NMDA receptor 2B. Neuron 62: 205-217. PubMed Citation: 19409266

Estella, C., Rieckhof, G., Calleja, M. and Morata, G. (2003). The role of buttonhead and Sp1 in the development of the ventral imaginal discs of Drosophila. Development 130: 5929-5941. 14561634

Esteve, P., et al. (2011). Secreted frizzled-related proteins are required for Wnt/β-catenin signalling activation in the vertebrate optic cup. Development 138(19): 4179-84. PubMed Citation: 21896628

Estrada, B. and Sánchez-Herrero, E. (2001). The Hox gene Abdominal-B antagonizes appendage development in the genital disc of Drosophila. Development 128: 331-339. 11152632

Fagotto, R., Guger, K. and Gumbiner, B. M. (1997). Induction of the primary dorsalizing center in Xenopus by the Wnt/GSK/ß-catenin signaling pathway, but not by Vg1, Activin or Noggin. Development 124: 453-460. PubMed Citation: 9053321

Fan, C. M., Lee, C. S. and Tessier-Lavigne, M. (1997). A role for WNT proteins in induction of dermomyotome. Dev. Biol. 191(1): 160-165. PubMed Citation: 9356179

Felix, J. T., Magarinos, M. and Diaz-Benjumea, F. J. (2007). Nab controls the activity of the zinc-finger transcription factors Squeeze and Rotund in Drosophila development. Development 134(10): 1845-52. Medline abstract: 17428824

Fire, A., Xu, S., Montgomery, M., Kostas, S.A., Driver, S.E., and Mello, C.C. (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391: 806-811. PubMed Citation: 9486653

Fischbach, K.-F. and Technau, G. (1984). Cell degeneration in the developing optic lobes of the small optic lobes and sine oculis mutants of Drosophila melanogaster. Dev. Biol. 104: 219-239. 6428950

Fleming, H. E., et al. (2008). Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell 2: 274-283. PubMed Citation: 18371452

Forrester, W. C., Kim, C. and Garriga, G. (2004). The Caenorhabditis elegans Ror RTK CAM-1 inhibits EGL-20/Wnt signaling in cell migration. Genetics 168(4): 1951-62. 15371357

Fortini, M. E., Lai, Z. C., Rubin, G. M. (1991). The Drosophila zfh-1 and zfh-2 genes encode novel proteins containing both zinc-finger and homeodomain motifs. Mech. Dev. 34: 113-122. 1680376

Franch-Marro, et al. (2005). Glypicans shunt the Wingless signal between local signalling and further transport. Development 132(4): 659-66.15647318

Franch-Marro, X., Martin, N., Averof, M. and Casanova, J. (2006). Association of tracheal placodes with leg primordia in Drosophila and implications for the origin of insect tracheal systems. Development 133(5): 785-90. 16469971

Franch-Marro, X., et al. (2008). Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex. Nat. Cell Biol. 10(2): 170-7. PubMed Citation: 18193037

Fredieu, J. R., et al. (1996). Xwnt-8 and lithium can act upon either dorsal mesodermal or neurectodermal cells to cause a loss of forebrain in Xenopus embryos. Dev. Biol. 186(1): 100-114

Freter, S., et al. (2009). Progressive restriction of otic fate: the role of FGF and Wnt in resolving inner ear potential. Development 135: 3415-3424. PubMed Citation: 18799542

Friedman, S.H., Dani, N., Rushton, E. and Broadie, K. (2013). Fragile X mental retardation protein regulates trans-synaptic signaling in Drosophila. Dis Model Mech 6: 1400-1413. PubMed ID: 24046358

Fromental-Ramain, C., Vanolst, L., Delaporte, C. and Ramain, P. (2008). pannier encodes two structurally related isoforms that are differentially expressed during Drosophila development and display distinct functions during thorax patterning. Mech. Dev. 125(1-2): 43-57. PubMed citation: 18042352

Fryer, C. J., White, J. B. and Jones, K. A. (2004). Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover. Mol. Cell 16: 509-520. PubMed Citation: 22959350

Fujioka, M., Jaynes, J. B. and Goto, T. (1995). Early even-skipped stripes act as morphogenetic gradients at the single cell level to establish engrailed expression. Development 121: 4371-4382

Fujise, M., et al. (2001). Regulation of dally, an integral membrane proteoglycan, and its function during adult sensory organ formation of Drosophila. Dev. Bio. 235: 433-448. 11437449

Furriols M. and Bray, S. (2000). Dissecting the mechanisms of Suppressor of Hairless function. Dev. Bio. 227: 520-532.

Fuß, B. and Hoch, M. (1998). Drosophila endoderm development requires a novel homeobox gene which is a target of Wingless and Dpp signalling. Mech. Dev. 79(1-2): 83-97. PubMed Citation: 10349623

Fuß, B., et al. (2001). Control of endoreduplication domains in the Drosophila gut by the knirps and knirps-related genes. Mech. Dev. 100: 15-23. 11118880 d&Cmd=ShowDetailView&TermToSearch=15546612">15546612

Gajewski, K., et al. (1998). Combinatorial control of Drosophila mef2 gene expression in cardiac and somatic muscle cell lineages. Dev. Genes Evol. 208(7): 382-92

Galindo, M. I., et al. (2011). Control of Distal-less expression in the Drosophila appendages by functional 3' enhancers. Dev. Biol. 353(2): 396-410. PubMed Citation: 21320482

Gallet, A., et al. (2000). Cubitus interruptus-independent transduction of the Hedgehog signal in Drosophila. Development 127: 5509-5522

Gallet, A., Rodriguez, R., Ruel, L. and Therond, P. P. (2003). Cholesterol modification of Hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to Hedgehog. Dev. Cell 4: 191-204. 12586063

Gallet, A., Staccini-Lavenant, L. and Thérond, P. P. (2008). Cellular trafficking of the glypican Dally-like is required for full-strength Hedgehog signaling and Wingless transcytosis. Dev. Cell 14: 712-725. PubMed Citation: 18477454

Gallitano-Mendel, A. and Finkelstein, R. (1997). Novel segment polarity gene interactions during embryonic head development in Drosophila. Dev. Biol. 192(2): 599-613

Gallitano-Mendel, A. and Finkelstein, R. (1998). Ectopic orthodenticle expression alters segment polarity gene expression but not head segment identity in the Drosophila embryo. Dev. Biol. 199(1): 125-137

Garcia-Garcia, M. J., et al. (1999). Different contributions of pannier and wingless to the patterning of the dorsal mesothorax of Drosophila. Development 126: 3523-3532

Garoia, F., et al. (2000). Cell behaviour of Drosophila fat cadherin mutations in wing development. Mech. Dev. 94: 95-109. 10842062

Garriock, R. J., et al. (2005). Wnt11-R, a protein closely related to mammalian Wnt11, is required for heart morphogenesis in Xenopus. Dev. Biol. 279: 179-192. 15708567

Gault, W. J., Olguin, P., Weber, U. and Mlodzik, M. (2012). Drosophila CK1-gamma, gilgamesh, controls PCP-mediated morphogenesis through regulation of vesicle trafficking. J Cell Biol 196: 605-621. PubMed ID: 22391037

Gerlitz, O. and Basler, K. (2002). Wingful, an extracellular feedback inhibitor of Wingless. Genes Dev. 16: 1055-1059. 12000788

Ghazi, A., Paul, L. and VijayRaghavan, K. (2003). Prepattern genes and signaling molecules regulate stripe expression to specify Drosophila flight muscle attachment sites. Mech. Dev. 120: 519-528. 12782269

Gieseler, K., et al. (1996). wingless and DWnt4, 2 Drosophila Wnt genes, have related expression, regulation and function during the embryonic development. C. R. Acad. Sci. III, Sci. 318: 1101-1110

Gieseler, K., et al. (2001). DWnt4 and wingless elicit similar cellular responses during imaginal development. Dev. Biol. 232(2): 339-50. PubMed citation: 11401396

Giráldez, A. J., Copley, R. R. and Cohen, S. M. (2002). HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient. Dev. Cell 2: 667-676. 12015973

Glinka, A., et al. (1998). Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 391(6665): 357-362

Glise, B., Jones, D. L. and Ingham, P. W. (2002). Notch and Wingless modulate the response of cells to Hedgehog signaling in the Drosophila wing. Dev. Bio. 248: 93-106 . 12142023

Go, M. J., Eastman, D. S. and Artavanis-Tsakonas, S. (1998). Cell proliferation control by Notch signaling in Drosophila development. Development 125: 2031-2040

Gofflot, F., Hall, M. and Morriss-Kay, G. M. (1997). Genetic patterning of the developing mouse tail at the time of posterior neuropore closure. Dev. Dyn. 210(4): 431-45

Gomperts, S. N. (1996). Clustering membrane proteins: It's all coming together with the PSD-95/SAP90 protein family. Cell 84: 659-662

Gómez-Skarmeta, J. L. and Modolell, J. (1996). araucan and caupolican provide a link between compartment subdivisions and patterning of sensory organs and veins in the Drosophila wing. Genes Dev. 10: 2935-45

Gómez-Skarmeta, J. L., de la Calle-Mustienes, E. and Modolell, J. (2001). The Wnt-activated Xiro1 gene encodes a repressor that is essential for neural development and downregulates Bmp4. Development 128: 551-560. 11171338

Gonzalez, F., Swales, L., Bejsovec, A., Skaer, H. and Martinez Arias, A. (1991). Secretion and movement of the wingless protein in the Drosophila embryo. Mech. Dev. 35, 43-54

Gonzalez-Gaitan, M. and Jackle, H. (1995). Invagination centers within the Drosophila stomatogastric nervous system anlage are positioned by Notch-mediated signaling which is spatially controlled through wingless. Development 121: 2313-2325

González-Gaitán, M. and Jäckle, H. (2000). Tip cell-derived RTK signaling initiates cell movements in the Drosophila stomatogastric nervous system anlage. EMBO Reports 1: 366-371. 11269504

Goodman, R. M., et al. (2007). Sprinter: a novel transmembrane protein required for Wg secretion and signaling. Development 133: 4901-4911. Medline abstract: 17108000

Gorfinkiel, N., Sánchez, L. and Guerrero, I. (2003). Development of the Drosophila genital disc requires interactions between its segmental primordia. Development 130: 295-305. 12466197

Gorivodsky, M. and Lonai, P. (2003). Novel roles of Fgfr2 in AER differentiation and positioning of the dorsoventral limb interface. Development 130: 5471-5479. 14507786

Gorsi, B. and Stringer, S. E. (2007). Tinkering with heparan sulfate sulfation to steer development, Trends Cell Biol. 17: 173-177. PubMed Citation: 17320398

Goss, A. M., et al. (2009). Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut. Dev. Cell 17(2): 290-8. PubMed Citation: 19686689

Goto, S., and Hayashi, S. (1997). Specification of the embryonic limb primordium by graded activity of Decapentaplegic. Development 124: 125-132. PubMed Citation: 9006073

Greaves, S., et al. (1999). A screen for identifying genes interacting with armadillo, the Drosophila homolog of beta-catenin. Genetics. 153(4): 1753-66. PubMed Citation: 10581282

Greco, T. L., et al. (1996). Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development. Genes Dev. 10(3): 313-24. PubMed Citation: 8595882

Green, J. L., Inoue, T. and Sternberg, P. W. (2007). The C. elegans ROR receptor tyrosine kinase, CAM-1, non-autonomously inhibits the Wnt pathway. Development 134(22): 4053-62. PubMed citation: 17942487

Green, J. L., Inoue, T. and Sternberg, P. W. (2008). Opposing Wnt pathways orient cell polarity during organogenesis. Cell 134(4): 646-56. PubMed Citation: 18724937

Grimm, S. and Pflugfelder, G. O. (1996). Control of the gene optomotor-blind in Drosophila wing development by decapentaplegic and wingless. Science 271: 1601-1604. PubMed Citation: 8599120

Grienenberger, A., et al. (2003). Tgfß signaling acts on a Hox response element to confer specificity and diversity to Hox protein function. Development 130: 5445-5455. 14507783

Gritzan, U., Hatini, V. and DiNardo, S. (1999). Mutual antagonism between signals secreted by adjacent Wingless and Engrailed cells leads to specification of complementary regions of the Drosophila parasegment. Development 126: 4107-4115. PubMed Citation: 10457019

Gros, J., et al. (2010). WNT5A/JNK and FGF/MAPK pathways regulate the cellular events shaping the vertebrate limb bud. Curr. Biol. 20(22): 1993-2002. PubMed Citation: 21055947

Gross, J. C., Chaudhary, V., Bartscherer, K. and Boutros, M. (2012). Active Wnt proteins are secreted on exosomes. Nat Cell Biol 14: 1036-1045. PubMed ID: 22983114

Grove, E. A., et al. (1998). The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice. Development 125(12): 2315-25. PubMed Citation: 9584130

Grumolato, L., et al. (2010). Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors. Genes Dev. 24(22): 2517-30. PubMed Citation: 21078818

Gujral, T. S., Chan, M., Peshkin, L., Sorger, P. K., Kirschner, M. W., and MacBeath, G. (2014). A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis. Cell 159: 844–856. Abstract

Guo, X., et al. (2004). Wnt/beta-catenin signaling is sufficient and necessary for synovial joint formation. Genes Dev. 18(19): 2404-17. 15371327

Hacker, U., Lin, X. and Perrimon, N. (1997). The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis. Development 124: 3565-3573

Hadeball, B., Borchers, A. and Wedlich, D. (1998). Xenopus cadherin-11 (Xcadherin-11) expression requires the Wg/Wnt signal. Mech. Dev. 72(1-2): 101-113

Haerry, T. E., et al. (1997). Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila. Development 124(16): 3055-3064

Halfon, M. S., et al. (2000). Ras pathway specificity is determined by the integration of multiple signal-activated and tissue-restricted transcription factors. Cell 103: 63-74.

Han, C., et al. (2005). Drosophila glypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disc. Development 132: 667-679. 15647319

Harterink, M., et al. (2011). Neuroblast migration along the anteroposterior axis of C. elegans is controlled by opposing gradients of Wnts and a secreted Frizzled-related protein. Development 138(14): 2915-24. PubMed Citation: 21653614

Hausmann, G., Banziger, C. and Basler, K. (2007). Helping Wingless take flight: how WNT proteins are secreted. Nat. Rev. Mol. Cell Biol. 8: 331-336. PubMed Citation: 17342185

Haussmann, I., White, K. and Soller, M. (2008). Erect wing regulates synaptic growth in Drosophila by integration of multiple signaling pathways. Genome Biol. 9: R73. PubMed Citation: 18419806

Hartenstein, V., Younossi-Hartenstein, A. and Lekven, A. (1994). Delamination and division in the Drosophila neurectoderm: spatiotemporal pattern, cytoskeletal dynamics, and common control by neurogenic and segment polarity genes. Dev. Biol. 165: 480-99. PubMed Citation: 7958415

Harterink, M., et al. (2011). A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion. Nature Cell Biol. 13: 914-923. PubMed Citation: 21725319

Hartmann, C. and Tabin, C. J. (2000). Dual roles of Wnt signaling during chondrogenesis in the chicken limb. Development 127: 3141-3159

Hatini, V., Bokor, P., Goto-Mandeville, R. and DiNardo, S. (2000). Tissue- and stage-specific modulation of Wingless signaling by the segment polarity gene lines. Genes Dev. 11: 1364-1376

Hatini, V. and DiNardo, S. (2001). Distinct signals generate repeating Striped pattern in the embryonic parasegment. Mol. Cell 7: 151-160. 11172720

Hatini, V., Green, R. B., Lengyel, J. A., Bray, S. J. and Dinardo, S. (2005). The Drumstick/Lines/Bowl regulatory pathway links antagonistic Hedgehog and Wingless signaling inputs to epidermal cell differentiation. Genes Dev. 19(6): 709-18. 15769943

Hays, R., Gibori, G. B. and Bejsovec, A. (1997). Wingless signaling generates pattern through two distinct mechanisms. Development 124(19): 3727-3736

Hays, R., et al. (1999). Patterning of Drosophila leg sensory organs through combinatorial signaling by Hedgehog, Decapentaplegic and Wingless. Development 126: 2891-2899

Hazelett, D. J., et al. (1998). decapentaplegic and wingless are regulated by eyes absent and eyegone and interact to direct the pattern of retinal differentiation in the eye disc. Development 125(18): 3741-3751

He, X., et al. (1997). A member of the Frizzled protein family mediating axis induction by Wnt-5A. Science 275: 1652-1654

Heberlein, U., Borod, E. R. and Chanut, F. A. (1998). Dorsoventral patterning in the Drosophila retina by wingless. 125(4): 567-577

Heisenberg, C. P., et al. (2000). Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation. Nature 405(6782): 76-81. 10811221

Held, L. I., et al. (1994). Interactions of decapentaplegic, wingless and Distal-less in the Drosophila leg. Roux's Arch. Dev. Biol. 203: 310-319

Held, L. I. and Heup, M. A. (1996). Genetic mosaic analysis of decapentaplegic and wingless gene function in the Drosophila leg. Dev. Genes Evol. 206: 180-194

Herman, M. A., et al. (1995). The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomously. Cell 83 (1): 101-110

Herman, M. A. (2001). C. elegans POP-1/TCF functions in a canonical Wnt pathway that controls cell migration and in a noncanonical Wnt pathway that controls cell polarity. Development 128: 581-590. 11171341

Herranz, H., Weng, R., Cohen, S. M. (2014) Crosstalk between epithelial and mesenchymal tissues in tumorigenesis and imaginal disc development. Curr Biol 24: 1476-1484. PubMed ID: 24980505

Heslip, T. R., et al. (1997). SHAGGY and DISHEVELLED exert opposite effects on wingless and decapentaplegic expression and on positional identity in imaginal discs. Development 124: 1069-1078

Hidalgo-Sanchez, M., et al. (1999). Comparative analysis of Otx2, Gbx2, Pax2, Fgf8 and Wnt1 gene expressions during the formation of the chick midbrain/hindbrain domain. Mech. Dev. 81(1-2): 175-8

Hikasa, H., et al. (2002). The Xenopus receptor tyrosine kinase Xror2 modulates morphogenetic movements of the axial mesoderm and neuroectoderm via Wnt signaling. Development 129: 5227-5239. 12399314

Hirabayashi, S., Baranski, T. J. and Cagan, R. L. (2013). Transformed Drosophila cells evade diet-mediated insulin resistance through wingless signaling. Cell 154: 664-675. PubMed ID: 23911328

Hirabayashi, S. and Cagan, R. L. (2015). Salt-inducible kinases mediate nutrient-sensing to link dietary sugar and tumorigenesis in Drosophila. Elife 4. PubMed ID: 26573956

Hirsinger, E., et al. (1997). Noggin acts downstream of Wnt and Sonic Hedgehog to antagonize BMP4 in avian somite patterning. Development 124(22): 4605-4614

Hobmayer, B., et al. (2000). WNT signaling molecules act in axis formation in the diploblastic metazoan Hydra. Nature 407: 186-189.

Hoch, M. and Pankratz, M. J. (1996). Control of gut development by fork head and cell signaling molecules in Drosophila. Mech. Dev. 58: 3-14

Hooper, J. E. (1994). Distinct pathways for autocrine and paracrine Wingless signalling in Drosophila embryos. Nature 372: 461-464

Hoppler, S. and Bienz, M. (1995). Two different thresholds of wingless signalling with distinct developmental consequences in the Drosophila midgut. EMBO J. 14(20): 5016-5026

Hoppler, S., Brown, J. D. and Moon, R. T. (1996). Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos. Genes Dev. 10: 2805-17

Hoppler, S. and Moon, R. T. (1998). BMP-2/-4 and Wnt-8 cooperatively pattern the Xenopus mesoderm. Mech. Dev. 71(1-2): 119-129

Howard, R. M. and Sundaram, M. V. (2002). C. elegans EOR-1/PLZF and EOR-2 positively regulate Ras and Wnt signaling and function redundantly with LIN-25 and the SUR-2 Mediator component. Genes Dev. 16: 1815-1827. 12130541

Hsieh, J. C., et al. (1999). A new secreted protein that binds to Wnt proteins and inhibits their activities. Nature 398(6726): 431-6

Hu, H., Hilton, M. J., Tu, X., Yu, K., Ornitz, D. M. and Long, F. (2005). Sequential roles of Hedgehog and Wnt signaling in osteoblast development. Development 132(1): 49-60. 15576404

Huang, F. Z., Bely, A. E. and Weisblat, D. A. (2001). Stochastic WNT signaling between nonequivalent cells regulates adhesion but not fate in the two-cell leech embryo. Curr. Biol. 11: 1-7. 11166173

Huang, Z. and Kunes, S. (1996). Hedgehog, transmitted along retinal axons, triggers neurogenesis in the developing visual centers of the Drosophila brain. Cell 86: 411-422

Hughes, C. L. and Kaufman, T. C. (2002). Exploring myriapod segmentation: The expression patterns of even-skipped, engrailed, and wingless in a Centipede. Dev. Bio. 247: 47-61. 12074551

Gieseler, K., et al. (2001). DWnt4 and wingless elicit similar cellular responses during imaginal development. Dev. Biol. 232: 339-350. PubMed ID: 11401396

Hummel, T., Schimmelpfeng, K. and Klambt, C. (1999). Commissure formation in the embryonic CNS of Drosophila. Identification of required gene functions. Dev. Biol. 209(2): 381-98

Hunter, C. P., et al. (1999). Hox gene expression in a single Caenorhabditis elegans cell is regulated by a caudal homolog and intercellular signals that inhibit Wnt signaling. Development 126(4): 805-814

Hayashi, T, (2011). A LIM-homeobox gene is required for differentiation of Wnt-expressing cells at the posterior end of the planarian body. Development 138(17): 3679-88. PubMed Citation: 21828095

Continued: Wingless references: Part 2/3 | Part 3/3

wingless : Biological Overview | Evolutionary Homologs | Transcriptional regulation |Targets of Activity | Protein Interactions | mRNA Transport | Developmental Biology | Effects of Mutation

Home page: The Interactive Fly © 1995, 1996 Thomas B. Brody, Ph.D.

The Interactive Fly resides on the
Society for Developmental Biology's Web server.