| Developmental and Signaling Pathways: Wingless Pathway |
| Zeng, Y. A. and Verheyen, E. M. (2004). Nemo is an inducible antagonist of Wingless signaling during Drosophila wing development. Development 131: 2911-2920. PubMed ID: 15169756 |
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Legend: The role of negative feedback inhibitors in Wingless (Wg) signaling. Drosophila Wg pathway components include the receptor Frizzled 2 (Fz2), Dishevelled (Dsh), Armadillo (Arm) and Pangolin (dTcf). Wg signaling is controlled by a number of induced inhibitors including Naked (Nkd) and Wingful/Notum (Wf). Wg also regulates Nemo expression and Nemo in turn can antagonize Wg during wing patterning (Zeng, 2004). |
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