Anderson, A. C., et al. (2005). The Notch regulator Numb links the Notch and TCR signaling pathways. J. Immunol. 174(2): 890-7. 15634911

Arimura, N., et al. (2005). Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones. Mol. Cell. Biol. 25: 9973-9984. 16260611

Bultje, R. S., et al. (2009). Mammalian Par3 regulates progenitor cell asymmetric division via notch signaling in the developing neocortex. Neuron 63(2): 189-202. PubMed Citation: 19640478

Babaoglan, A. B., O'Connor-Giles, K. M., Mistry, H., Schickedanz, A., Wilson, B. A. and Skeath, J. B. (2009). Sanpodo: a context-dependent activator and inhibitor of Notch signaling during asymmetric divisions. Development 136(24): 4089-98. PubMed Citation: 19906847

Bani-Yaghoub, M., Kubu, C. J., Cowling, R., Rochira, J., Nikopoulos, G. N., Bellum, S. and Verdi, J. M. (2007). A switch in numb isoforms is a critical step in cortical development. Dev. Dyn. 236: 696-705. Medline abstract: 17253625

Bellaïche, Y., et al. (2001). The Partner of Inscuteable/Discs-large complex is required to establish planar polarity during asymmetric cell division in Drosophila. Cell 106: 355-366. 11509184

Ben-Yaacov, S., et al. (2001). Wasp, the Drosophila Wiskott-Aldrich syndrome gene homologue, is required for cell fate decisions mediated by Notch signaling. J. Cell Biol. 152: 1-14. 11149916

Berdnik, D. and Knoblich, J. (2002a). Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis. Curr. Biol. 12: 640-647. 11967150

Berdnik, D., Török, G., González-Gaitán, M. and Knoblich, J. A. (2002b). The endocytic protein a-Adaptin is required for Numb-mediated asymmetric cell division in Drosophila. Dev. Cell 3: 221-231. 12194853

Bhalerao, S., Berdnik, D., Torok, T. and Knoblich, J. A. (2005). Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila. Curr. Biol. 15(17): 1583-90. Medline abstract: 16139215

Bhat, K. M., Gaziova, I. and Katipalla, S. (2011). Neuralized mediates asymmetric division of neural precursors by two distinct and sequential events: promoting asymmetric localization of Numb and enhancing activation of Notch-signaling. Dev. Biol. 351(1): 186-98. PubMed Citation: 21147089

Bowman, S. K. et al. (2008). The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila. Dev. Cell 14: 535-546. PubMed Citation: 18342578

Brewster, R. and Bodmer, R. (1995). Origin and specification of type II sensory neurons in Drosophila. Development 121: 2923-2936. 7555719

Buescher, M., et al. (1998). Binary sibling neuronal cell fate decisions in the Drosophila embryonic central nervous system are nonstochastic and require inscuteable-mediated asymmetry of ganglion mother cells. Genes Dev. 12(12): 1858-1870

Calderwood, D. A., et al. (2003). Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling. Proc. Natl. Acad. Sci. 100: 2272-2277. 12606711

Carmena, A., et al. (1998). inscuteable and numb mediate asymmetric muscle progenitor cell divisions during Drosophila myogenesis. Genes Dev. 12(3): 304-315. 9450926

Caussinus, E. and Gonzalez, C. (2005). Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster. Nature Genetics 37: 1125-9. 16142234

Cayouette, M., et al. (2001). Asymmetric segregation of numb in retinal development and the influence of the pigmented epithelium. J. Neurosci. 21(15): 5643-5651. 11466435

Cheah, P. Y., Chia, W. and Yang, X. (2000). Jumeaux, a novel Drosophila winged-helix family protein, is required for generating asymmetric sibling neuronal cell fates. Development 127(15): 3325-3335. 10887088

Cheng, X., et al. (2008). Numb mediates the interaction between Wnt and Notch to modulate primitive erythropoietic specification from the hemangioblast. Development 135(20): 3447-58. PubMed Citation: 18799543

Chiba, A., et al. (1993). Growth cone choices of Drosophila motoneurons in response to muscle fiber mismatch. J Neurosci 13: 714-32. PubMed Citation: 8426233

Chien, C. T., et al. (1998). Numb-associated kinase interacts with the phosphotyrosine binding domain of Numb and antagonizes the function of Numb in vivo. Mol. Cell. Biol. 18(1): 598-607. PubMed Citation: 9418906

Colalucam, I. N., et al. (2008). NUMB controls p53 tumour suppressor activity. Nature 451(7174): 76-80. Medline abstract: 18172499

Couturier, L., Vodovar, N. and Schweisguth, F. (2012). Endocytosis by Numb breaks Notch symmetry at cytokinesis. Nat. Cell Biol. 14(2): 131-9. PubMed Citation: 22267085

Dong, X., et al., (1997). Control of G1 in the developing Drosophila eye: rca1 regulates Cyclin A. Genes Dev. 11: 94-105. 9000053

Dho, S. E., et al. (1999). Characterization of four mammalian Numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain. J. Biol. Chem. 274(46): 33097-33104. PubMed Citation: 10551880

Dye, C. A., et al. (1998). The Drosophila sanpodo gene controls sibling cell fate and encodes a tropomodulin homolog, an actin/tropomyosin-associated protein. Development 125: 1845-1856. PubMed Citation: 9550717

Eddison, M., Le Roux, I. and Lewis, J. (2000). Notch signaling in the development of the inner ear: Lessons from Drosophila. Proc. Natl. Acad. Sci. 97: 11692-11699. PubMed Citation: 11050197

Edenfeld, G., Altenhein, B., Zierau, A., Cleppien, D., Krukkert, K., Technau, G. and Klämbt, C. (2007). Notch and Numb are required for normal migration of peripheral glia in Drosophila. Dev. Biol. 301(1): 27-37. Medline abstract: 17157832

Endo, K., Aoki, T., Yoda, Y., Kimura, K. and Hama, C. (2007). Notch signal organizes the Drosophila olfactory circuitry by diversifying the sensory neuronal lineages. Nat. Neurosci. 10(2): 153-60. Medline abstract: 17220884

Freedman, D. A., Wu, L. & Levine, A. J. (1999). Functions of the MDM2 oncoprotein. Cell Mol. Life Sci. 55: 96-107. PubMed Citation: 10065155

Frise, E., et al. (1996). The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage. Proc. Natl. Acad. Sci. 93: 11925-32. 8876239

Gho, M. and Schweisguth, F. (1998). Frizzled signalling controls orientation of asymmetric sense organ precursor cell divisions in Drosophila. Nature 393(6681): 178-181. PubMed Citation: 9603522

Gho, M., Bellaiche, Y. and Schweisguth, F., (1999). Revisiting the Drosophila microchaete lineage: a novel intrinsically asymmetric cell division generates a glial cell. Development 126: 3573-3584. PubMed Citation: 10409503

Giniger, E. (1998) A role for Abl in Notch signaling. Neuron 20: 667-681. 9581760

Gomez, M. R. and Bate, M. (1997). Segregation of myogenic lineages in Drosophila requires numb. Development 124(23): 4857-4866

Guo, M., Bier, E., Jan, L.Y. and Jan, Y.N. (1995). tramtrack acts downstream of numb to specify distinct daughter cell fates during asymmetric cell divisions in the Drosophila PNS. Neuron 14(5): 913-25

Guo, M., Jan, L. Y. and Jan, Y. N. (1996). Control of daughter cell fates during asymmetric division: Interaction of Numb and Notch. Neuron 17: 21-41

Han, Z. and Bodmer, R. (2003). Myogenic cells fates are antagonized by Notch only in asymmetric lineages of the Drosophila heart, with or without cell division. Development 130: 3039-3051. 12756185

Ho, L. H., et al. (2009). A tumor suppressor function for caspase-2. Proc. Natl. Acad. Sci. 106: 5336-5341. PubMed Citation: 19279217

Huang, E. J. et al. (2005). Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization. Genes Dev. 19(1): 138-51. 15598981

Hattendorf, D. A., et al. (2007). Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism. Nature 446: 567-571. PubMed Citation: 17392788

Hutterer, A. and Knoblich, J. A. (2005). Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs. EMBO Rep. 6(9): 836-42. Medline abstract: 16113648

Justice, N., Roegiers, F. Jan, L. Y., and Jan, Y. H. (2003). Lethal giant larvae acts together with Numb in Notch inhibition and cell fate specification in the Drosophila adult sensory organ precursor lineage. Curr. Biol. 13: 778-783. 12725738

Juven-Gershon, T., Shifman, O., Unger, T., Elkeles, A., Haupt, Y. & Oren, M. (1998). The Mdm2 oncoprotein interacts with the cell fate regulator Numb. Mol. Cell Biol. 7: 3974-3982

Katanaev, V. L., Ponzielli, R., Semeriva, M. and Tomlinson, A. (2005). Trimeric G protein-dependent Frizzled signaling in Drosophila. Cell 120: 111-122. 15652486

Katanaev, V. L., Tomlinson, A. (2006). Dual roles for the trimeric G protein Go in asymmetric cell division in Drosophila. Proc. Natl. Acad. Sci. 103: 6524-6529. 16617104

Knoblich, J. A., Jan, L. Y. and Jan, Y. N. (1995). Asymmetric segregation of Numb and Prospero during cell division. Nature 377: 624-627

Knoblich, J. A., Jan, L. Y. and Jan, Y. N. (1997). The N terminus of the Drosophila Numb protein directs membrane association and actin-dependent asymmetric localization. Proc. Natl. Acad. Sci. 94(24): 13005-13010

Kraut, R.,K. et al. (1996b). Role of inscuteable in orienting asymmetric cell divisions in Drosophila. Nature 383: 50-55

Kubu, C. J., et al. (2002). Developmental changes in Notch1 and Numb expression mediated by local cell-cell interactions underlie progressively increasing delta sensitivity in neural crest stem cells. Dev. Biol. 244: 199-214. 11900468

Kuo, C. T., et al. (2006). Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. Cell 127(6): 1253-64. Medline abstract: 17174898

Lear, B. C., Skeath, J. B. and Patel, N. H. (1999). Neural cell fate in rca1 and cycA mutants: the roles of intrinsic and extrinsic factors in asymmetric division in the Drosophila central nervous system. Mech. Dev. 207-219. PubMed Citation: 10534619

Lee, C. Y., et al. (2006). Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation. Genes Dev. 20(24): 3464-74. Medline abstract: 17182871

Li, H.-S., et al. (2004). Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron 40: 1105-1118. 14687546

Li, S.-C., et al. (1997). High-affinity binding of the Drosophila numb phosphotyrosine-binding domain to peptides containing a gly-pro-(p)Tyr motif. Proc. Natl. Acad. Sci. 94(14): 7204-7209. PubMed Citation: 9207069

Liebl, E. C., et al. (2003). Interactions between the secreted protein Amalgam, its transmembrane receptor Neurotactin and the Abelson tyrosine kinase affect axon pathfinding. Development 130: 3217-3226. 12783792

Lin, H. and Spradling, A. C. (1995). Fusome asymmetry and oocyte determination in Drosophila. Dev. Genet. 16: 6-12. PubMed Citation: 7758245

Lin, S., et al. (2010). Lineage-specific effects of Notch/Numb signaling in post-embryonic development of the Drosophila brain. Development. 137(1):43-51. PubMed Citation: 20023159

Lin, Y. T., Barske, L., DeFalco, T. and Capel, B. (2017). Numb regulates somatic cell lineage commitment during early gonadogenesis in mice. Development 144(9):1607-1618. PubMed ID: 28360133

Lu, B., Rothenberg, M., Jan, L. Y. and Jan, Y. N. (1998). Partner of numb colocalizes with numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors. Cell 95: 225-23. PubMed Citation: 9790529

Lu, B., Ackerman, L., Jan, L. Y., Jan, Y. N. (1999). Modes of protein movement that lead to the asymmetric localization of partner of Numb during Drosophila neuroblast division. Molec. Cell 4: 883-891. PubMed Citation: 10635314.

Lu, B., et al. (2001). Adherens junctions inhibit asymmetric division in the Drosophila epithelium. Nature 409: 522-525. 11206549

Lundell, M. J., et al. (2003). The regulation of apoptosis by Numb/Notch signaling in the serotonin lineage of Drosophila. Development 130: 4109-4121. 12874131

Manning, L. and Doe, C. Q. (1999). Prospero distinguishes sibling cell fate without asymmetric localization in the Drosophila adult external sense organ lineage. Development 26: 2063-2071. PubMed Citation: 10207132

Mayer, B., Emery, G., Berdnik, D., Wirtz-Peitz, F. and Knoblich, J. A. (2005). Quantitative analysis of protein dynamics during asymmetric cell division. Curr. Biol. 15(20): 1847-54. Medline abstract: 16243032

McGill, M. A. and McGlade, C. J. (2003). Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain. J. Biol. Chem. 278(25): 23196-203. 12682059

Mehta, B. and Bhat, K. M. (2001). Slit signaling promotes the terminal asymmetric division of neural precursor cells in the Drosophila CNS. Development 128: 3161-3168. 11688564

Merdes, G., Soba, P., Loewer, A., Bilic, M. V., Beyreuther, K. and Paro, R. (2004). Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila. EMBO J. 23(20): 4082-95. 15385958

Nagel, A. C., Maier, D. and Preiss, A. (2000). Su(H)-independent activity of Hairless during mechano-sensory organ formation in Drosophila. Mech. Dev. 94: 3-12. PubMed Citation: 10842054

Nie, J., et al. (2002). LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation EMBO J. 21: 93-102. 11782429

Nishimura, T., et al. (2003). CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth. Nat Cell Biol. 5(9): 819-26. 12942088

Nishimura, T. and Kaibuchi, K. (2007). Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3. Dev. Cell 13(1): 15-28. Medline abstract: 17609107

O'Connor-Giles, K. M. and Skeath, J. B. (2003). Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila. Dev. Cell 5: 231-243. 12919675

Ohshiro, T., et al. (2000). Role of cortical tumor-suppressor proteins in asymmetric division of Drosophila neuroblast. Nature 408: 593-596. 21003824

Orgogozo, V., Schweisguth, F. and Bellaïche, Y. (2002). Binary cell death decision regulated by unequal partitioning of Numb at mitosis. Development 129: 4677-4684. 12361960

Ouyang, Y., et al. (2011). Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila. Development 138(11): 2185-96. PubMed Citation: 21558368

Park, M., Yaich, L. E. and Bodmer, R. (1998). Mesodermal cell fate decisions in Drosophila are under the control of the lineage genes numb, Notch, and sanpodo. Mech. Dev. 75(1-2): 117-26. PubMed Citation: 9739121

Peng, C.-Y., et al. (2000). The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts. Nature 408: 596-600. 21003825

Petersen, P. H., et al. (2002). Progenitor cell maintenance requires numb and numblike during mouse neurogenesis. Nature 419: 929-934. 12410312

Rasin, M. R., et al. (2007). Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat. Neurosci. 10(7): 819-27. Medline abstract: 17589506

Rath, P., et al. (2002). Inscuteable-independent apicobasally oriented asymmetric divisions in the Drosophila embryonic CNS. EMBO Reports 3: 660-665. 12101099

Rebeiz, M., Reeves, N. L. and Posakony, J. W. (2002). SCORE: A computational approach to the identification of cis-regulatory modules and target genes in whole-genome sequence data. Proc. Natl. Acad. Sci. 99: 9888-9893. PubMed Citation: 12107285

Rebeiz, M., Miller, S. W. and Posakony, J. W. (2011). Notch regulates numb: integration of conditional and autonomous cell fate specification. Development 138(2): 215-25. PubMed Citation: 21148185

Rhyu, M.S., et al. (1994). Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell 76: 477-491. PubMed Citation: 8313469

Rhyu, M. S. and Knoblich, J. (1995). Spindle orientation and asymmetric cell fate. Cell 82: 523-526. PubMed Citation: 7664329

Roegiers, F., et al. (2001a). Two types of asymmetric divisions in the Drosophila sensory organ precursor cell lineage. Nature Cell Bio. 3: 58-67 . 11146627

Roegiers, F., Younger-Shepherd, S., Jan, L. Y. and Jan, Y. N. (2001b). Bazooka is required for localization of determinants and controlling proliferation in the sensory organ precursor cell lineage in Drosophila. Proc. Natl. Acad. Sci. 98: 14469-14474. 11734647

Roegiers, F., Jan, L. Y. and Jan, Y. N. (2005). Regulation of membrane localization of Sanpodo by Lethal giant larvae and Neuralized in asymmetrically dividing cells of Drosophila sensory organs. Mol Biol Cell.. 15901829

Roncarati, R., Sestan, N., Scheinfeld, M. H., Berechid, B. E., Lopez, P. A, Meucci, O., McGlade, J. C., Rakic, P. and D'Adamio, L. (2002). The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling. Proc. Natl. Acad. Sci. 99: 7102-7107. 12011466

Salcini, A. E., et al. (1997). Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module. Genes Dev. 11: 2239-2249. 9303539

Santolini, E., et al. (2000). Numb is an endocytic protein. J. Cell Biol. 151: 1345-1352. 11121447

Schuldt, A. J. and Brand, A. H. (1999). Mastermind acts downstream of Notch to specify neuronal cell fates in the Drosophila central nervous system. Dev. Biol. 205(2): 287-295. PubMed Citation: 9917364

Shen, C.-P., Jan, L. Y. and Jan, Y. N. (1997). Miranda is required for the asymmetric localization of Prospero during mitosis in Drosophila. Cell 90: 449-458. PubMed Citation: 9267025

Shen, Q., Zhong, W., Jan, Y. N. and Temple, S. (2002). Asymmetric Numb distribution is critical for asymmetric cell division of mouse cerebral cortical stem cells and neuroblasts. Development 129: 4843-4853. 12361975

Skeath, J. B. and Doe, C. Q. (1998). Sanpodo and Notch act in opposition to Numb to distinguish sibling neuron fates in the Drosophila CNS. Development 125: 1857-1865. PubMed Citation: 9550718

Smith, C. A., et al. (2007). aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb. EMBO J. 26: 468-480. Medline abstract: 17203073

Spana, E.P. (1995). Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS. Development 121: 3489-3491. PubMed Citation: 8582263

Su, M.-T., et al. (1999). The Drosophila homeobox genes zfh-1 and even-skipped are required for cardiac-specific differentiation of a numb-dependent lineage decision Development 126: 3241-3251. PubMed Citation: 10375513

Susini, L., et al. (2001). Siah-1 binds and regulates the function of Numb. Proc. Natl. Acad. Sci. 98: 15067-15072. 11752454

Tio, M., et al. (1999). A functional analysis of Inscuteable and its roles during Drosophila asymmetric cell divisions. J. Cell Sci. 112(Pt 10): 1541-1551. PubMed Citation: 10212148

Tokumitsu, H., et al. (2005). Phosphorylation of Numb family proteins. Possible involvement of Ca2+/calmodulin-dependent protein kinases. J. Biol. Chem. 280(42): 35108-18. 16105844

Toriya, M., Tokunaga, A., Sawamoto, K., Nakao, K. and Okano, H. (2006). Distinct functions of human numb isoforms revealed by misexpression in the neural stem cell lineage in the Drosophila larval brain. Dev. Neurosci. 28(1-2): 142-55. 16508311

Udolph, G., Rath, P. and Chia, W. (2001). A requirement for Notch in the genesis of a subset of glial cells in the Drosophila embryonic central nervous system which arise through asymmetric divisions. Development 128: 1457-1466. 11262244

Uemura, T., Shepherd, S., Ackerman, L., Jan, L.Y. and Jan, Y.N. (1989). numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos. Cell 58: 349-360. PubMed Citation: 2752427

Van De Bor, V. and Giangrande, A. (2001). Notch signaling represses the glial fate in fly PNS. Development 128: 1381-1390. 11262238

Verdi, J. M., et al. (1999). Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage. Proc. Natl. Acad. Sci. 96: 10472-10476. PubMed Citation: 10468633

Vervoort, M., et al. (1997). Genetic basis of the formation and identity of type I and type II neurons in Drosophila embryos. Development (14): 2819-2828. PubMed Citation: 9226453

Wai, P., Truong, B. and Bhat, K. M. (1999). Cell division genes promote asymmetric interaction between Numb and Notch in the Drosophila CNS. Development 126(12): 2759-2770. PubMed Citation: 10331986

Wakamatsu, Y., et al. (1999). NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1. Neuron 23: 71-81. PubMed Citation: 10402194

Wakamatsu, Y., Maynard, T. M. and Weston, J. A. (2000). Fate determination of neural crest cells by NOTCH-mediated lateral inhibition and asymmetrical cell division during gangliogenesis. Development 127: 2811-2821. Medline abstract: 10851127

Wakamatsu, Y., et al. (2007). Transitin, a nestin-like intermediate filament protein, mediates cortical localization and the lateral transport of Numb in mitotic avian neuroepithelial cells. Development 134: 2425-2433. Medline abstract: 17522158

Wan, S., Cato, A.-M. and Skaer, H. (2000). Multiple signalling pathways establish cell fate and cell number in Drosophila Malpighian tubules, Dev. Biol. 217: 153-165. PubMed Citation: 10625542

Wang, C., et al. (2009). Protein phosphatase 2A regulates self-renewal of Drosophila neural stem cells. Development 136(13): 2287-96. PubMed Citation: 19502489

Wang, H., Somers, G. W., Bashirullah, A., Heberlein, U., Yu, F. and Chia, W. (2006). Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts. Genes Dev. 20(24): 3453-63. Medline abstract: 17182870

Wang, H., Ouyang, Y., Somers, W. G., Chia, W. and Lu, B. (2007). Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon. Nature 449(7158): 96-100. Medline abstract: 17805297

Wang, S., Younger-Shepherd, S., Jan, L. Y. and Jan, Y. N. (1997). Only a subset of the binary cell fate decisions mediated by Numb/Notch signaling in Drosophila sensory organ lineage requires Suppressor of Hairless. Development 124(22): 4435-4446. PubMed Citation: 9409662

Wang, W., Liu, W., Wang, Y., Zhou, L., Tang, X. and Luo, H. (2011). Notch signaling regulates neuroepithelial stem cell maintenance and neuroblast formation in Drosophila optic lobe development. Dev. Biol. 350(2): 414-28. PubMed Citation: 21146517

Ward, E. J. and Skeath, J. B. (2000). Characterization of a novel subset of cardiac cells and their progenitors in the Drosophila embryo. Development 127: 4959-4969. 11044409

Wirtz-Peitz, F., Nishimura, T. and Knoblich, J. A. (2008). Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization. Cell 135: 161-173. PubMed Citation: 18854163

Wu, Y. C., Lee, K. S., Song, Y., Gehrke, S. and Lu, B. (2017). The bantam microRNA acts through Numb to exert cell growth control and feedback regulation of Notch in tumor-forming stem cells in the Drosophila brain. PLoS Genet 13(5): e1006785. PubMed ID: 28520736

Yaich, L., et al. (1998). Functional analysis of the numb phosphotyrosine-binding domain using site-directed mutagenesis. J. Biol. Chem. 273(17): 10381-10388. PubMed Citation: 9553095

Zhao, C., Guo, H., Li, J., Myint, T., Pittman, W., Yang, L., Zhong, W., Schwartz, R. J., Schwarz, J. J., Singer, H. A., Tallquist, M. D. and Wu, M. (2014). Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation. Development 141: 281-295. PubMed ID: 24335256

Zhong, W. et al. (1996). Asymmetric localization of a mammalian Numb homolog during mouse cortical Neurogenesis. Neuron 17: 43-53. PubMed Citation: 8755477

Zhong, W., et al. (1997). Differential expression of mammalian Numb, Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis. Development 124: 1887-1897. PubMed Citation: 9169836

Zhong, W., et al. (2000). Mouse numb is an essential gene involved in cortical neurogenesis. Proc. Natl. Acad. Sci. 97: 6844-6849. Medline abstract: 10841580

Zilian, O., et al. (2001). Multiple roles of mouse Numb in tuning developmental cell fates. Curr. Biol. 11: 494-501. Medline abstract: 11412999

Zhou, Y., Atkins, J. B., Rompani, S. B., Bancescu, D. L., Petersen, P. H., Tang, H., Zou, K. M., Stewart, S. B. and Zhong, W. (2007). The mammalian Golgi regulates Numb signaling in asymmetric cell division by releasing ACBD3 during mitosis. Cell 129: 163-178. Medline abstract: 17418793

Zwahlen, C., Li, S. C., Kay, L. E., Pawson, T. and Forman-Kay, J, D. (2000). Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb. EMBO J. 19(7): 1505-15. PubMed Citation: 10747019

numb: Biological Overview | Evolutionary Homologs | Regulation | Developmental Biology | Effects of Mutation

date revised: 10 March 2015 

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