Adler, P.N., Vinson, C., Park, W.J., Conover, S. and Klein, L. (1990). Molecular structure of frizzled, a Drosophila tissue polarity gene. Genetics 126: 401-416. PubMed Citation: 2174014

Adler, P., Charlton, J. and Liu, J. (1998). Mutations in the cadherin superfamily member gene dachsous cause a tissue polarity phenotype by altering frizzled signaling. Development 125(5): 959-968. PubMed Citation: 9449678

Adler, P. N., Taylor, J. and Charlton, J. (2000). The domineering non-autonomy of frizzled and Van Gogh clones in the Drosophila wing is a consequence of a disruption in local signaling. Mech. Dev. 96: 197-207. PubMed Citation: 10960784

Adler, P. N. (2002). Planar signaling and morphogenesis in Drosophila. Dev. Cell 2: 525-535. 12015961

Aigouy, B., et al. (2010). Cell flow reorients the axis of planar polarity in the wing epithelium of Drosophila. Cell 142: 773-786. PubMed Citation: 20813263

Amonlirdviman, K., et al. (2005). Mathematical modeling of planar cell polarity to understand domineering nonautonomy. Science 307: 423-426. 15662015

Axelrod, J. D., et al. (1998). Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes Dev. 12(16): 2610-2622. PubMed Citation: 9716412

Axelrod, J. D. (2001). Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling. Genes Dev. 15: 1182-1187. 11358862

Axelrod, J. (2009). Progress and challenges in understanding planar cell polarity signaling. Semin. Cell Dev. Biol. 20: 964-971. PubMed Citation: 19665570

Bastock, R. and Strutt, D. (2007). The planar polarity pathway promotes coordinated cell migration during Drosophila oogenesis. Development 134(17): 3055-64. PubMed citation; Online text Beermann, A., et al. (2012). A context-dependent combination of Wnt receptors controls axis elongation and leg development in a short germ insect. Development 138: 2793-2805. PubMed Citation: 21652652

Bellaïche, Y., et al. (2001). The Partner of Inscuteable/Discs-large complex is required to establish planar polarity during asymmetric cell division in Drosophila. Cell 106: 355-366. 11509184

Bhanot, P, et al. (1996). A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 382: 225-230. PubMed Citation: 8717036

Bhat, K. M. (1998). frizzled and frizzled 2 play a partially redundant role in wingless signaling and have similar requirements to Wingless in neurogenesis. Cell 95: 1027-1036.

Beermann, A., et al. (2012). A context-dependent combination of Wnt receptors controls axis elongation and leg development in a short germ insect. Development 138: 2793-2805. PubMed Citation: 21652652

Borovina, A., Superina, S., Voskas, D. and Ciruna, B. (2010). Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia. Nat Cell Biol 12: 407-412. PubMed ID: 20305649

Boutros, M., Mihaly, J., Bouwmeester, T. and Mlodzik, M. (2000). Signaling specificity by Frizzled receptors in Drosophila. Science 288(5472): 1825-8. PubMed Citation: 10846164

Carvajal-Gonzalez, J.M., Roman, A.C. and Mlodzik, M. (2016). Positioning of centrioles is a conserved readout of Frizzled planar cell polarity signalling. Nat Commun 7: 11135. PubMed ID: 27021213

Chae, J., et al. (1999). The Drosophila tissue polarity gene starry night encodes a member of the protocadherin family. Development 126(23): 5421-9. PubMed Citation: 10556066

Chan, S.D. et al. (1992). Two homologs of the Drosophila polarity gene frizzled (fz) are widely expressed in mammalian tissues. J. Bio. Chem. 267: 25202-25207. PubMed Citation: 1334084

Chanut, F. and Heberlein, V. (1995). Role of the morphogenetic furrow in establishing polarity in the Drosophila eye. Development 121: 4085-94. PubMed Citation: 8575309

Chen, C.-m. and Struhl, G. (1999). Wingless transduction by the Frizzled and Frizzled2 proteins of Drosophila. Development 126: 5441-5452. PubMed Citation: 10556068

Chen, W.-S., et al. (2008). Asymmetric homotypic interactions of the atypical cadherin Flamingo mediate intercellular polarity signaling. Cell 133: 1093-1105. PubMed Citation: 18555784

Chin, M. L. and Mlodzik, M. (2013). The Drosophila selectin Furrowed mediates intercellular planar cell polarity interactions via Frizzled stabilization. Dev Cell. PubMed ID: 23973164

Cho, B. and Fischer, J. A. (2011). Ral GTPase promotes asymmetric Notch activation in the Drosophila eye in response to Frizzled/PCP signaling by repressing ligand-independent receptor activation. Development 138(7): 1349-59. PubMed Citation: 21350007

Classen, A.-K., Anderson, K. I., Marois, E. and Eaton, S. (2005). Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway. Dev. Cell 9(6): 805-17. 16326392

Cong, F., Schweizer, L. and Varmus, H. (2004). Wnt signals across the plasma membrane to activate the ß-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP. Development 131: 5103-5115. 15459103

Clandinin, T. R. and Zipursky, S. L. (2000). Afferent growth cone interactions control synaptic specificity in the Drosophila visual system. Neuron 28: 427-436. PubMed Citation: 11144353

Collier, S. and Gubb, D. (1997). Drosophila tissue polarity requires the cell-autonomous activity of the fuzzy gene, which encodes a novel transmembrane protein. Development 124(20): 4029-4037. PubMed Citation: 9374400

Cooper, M. T. and Bray, S. J. (1999). Frizzled regulation of Notch signalling polarizes cell fate in the Drosophila eye. Nature 397(6719): 526-30. PubMed Citation: 10028969

Das, G., Reynolds-Kenneally, J. and Mlodzik, M. (2002). The atypical cadherin Flamingo links Frizzled and Notch signaling in planar polarity establishment in the Drosophila eye. Dev. Cell 2: 655-666. 12015972

Das, G., et al. (2004). Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes. Development 131: 4467-4476. PubMed citation: 15306567

David, N. B., Martin, C. A., Segalen, M., Rosenfeld, F., Schweisguth, F. and Bellaiche, Y. (2005). Drosophila Ric-8 regulates Galphai cortical localization to promote Galphai-dependent planar orientation of the mitotic spindle during asymmetric cell division. Nat Cell Biol 7: 1083-1090. PubMed ID: 16228010

Deardorff, M. A., et al. (1998). Frizzled-8 is expressed in the spemann organizer and plays a role in early morphogenesis. Development 125(14): 2687-2700. PubMed Citation: 9636083

del Alamo, D. and Mlodzik, M. (2006). Frizzled/PCP-dependent asymmetric Neuralized expression determines R3/R4 Fates in the Drosophila eye. Dev. Cell 11: 887-894. Medline abstract: 17141162

Devenport, D. and Fuchs, E. (2008). Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol 10: 1257-1268. PubMed ID: 18849982

Dickinson, A. J. G and Sive, H. L. (2009). The Wnt antagonists Frzb-1 and Crescent locally regulate basement membrane dissolution in the developing primary mouth. Development 136: 1071-1081. PubMed Citation: 19224982

Djiane, A., Yogev, S. and Mlodzik, M. (2005). The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye. Cell 121: 621-631. 15907474

Doyle, K., Hogan, J., Lester, M. and Collier, S. (2008). The Frizzled planar cell polarity signaling pathway controls Drosophila wing topography. Dev. Biol. 317(1): 354-67. PubMed Citation: 18384764

Fanto, M., Mayes, C. A. and Mlodzik, M. (1998). Linking cell-fate specification to planar polarity: determination of the R3/R4 photoreceptors is a prerequisite for the interpretation of the Frizzled mediated polarity signal. Mech. Dev. 74(1-2): 51-58. PubMed Citation: 9651479

Fanto, M. and Mlodzik, M. (1999). Asymmetric Notch activation specifies photoreceptors R3 and R4 and planar polarity in the Drosophila eye. Nature 397(6719): 523-6. PubMed Citation: 10028968

Feiguin, F., Hannus, M., Mlodzik, M. and Eaton, S. (2001). The ankyrin repeat protein Diego mediates Frizzled-dependent planar polarization. Dev. Cell 1: 93-101. PubMed citation: 11703927

Fire, A., Xu, S., Montgomery, M., Kostas, S.A., Driver, S.E., and Mello, C.C. (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391: 806-811. PubMed Citation: 9486653

Garoia, F., et al. (2000). Cell behaviour of Drosophila fat cadherin mutations in wing development. Mech. Dev. 94: 95-109. 10842062

Gho, M. and Schweisguth, F. (1998). Frizzled signalling controls orientation of asymmetric sense organ precursor cell divisions in Drosophila. Nature 393(6681): 178-81. PubMed Citation: 10028968

Gomperts, S. N. (1996). Clustering membrane proteins: It's all coming together with the PSD-95/SAP90 protein family. Cell 84: 659-662. PubMed Citation: 8625403

Gray, R. S., Roszko, I. and Solnica-Krezel, L. (2011). Planar cell polarity: coordinating morphogenetic cell behaviors with embryonic polarity. Dev Cell 21: 120-133. PubMed ID: 21763613

Gubb, D. and A. Garcia-Bellido (1982). A genetic analysis of the determination of cuticular polarity during development in Drosophila melanogaster. J. Embryol. Exp. Morphol. 68: 37-57. PubMed Citation: 6809878

Gubb, D., et al. (1999). The balance between isoforms of the prickle LIM domain protein is critical for planar polarity in Drosophila imaginal discs. Genes Dev. 13(17): 2315-27. PubMed Citation: 10485852

Gujral, T. S., Chan, M., Peshkin, L., Sorger, P. K., Kirschner, M. W., and MacBeath, G. (2014). A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis. Cell 159: 844–856. Abstract

Han, C., et al. (2005). Drosophila glypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disc. Development 132: 667-679. 15647319

Harris, K. E. and Beckendorf, S. K. (2007). Different Wnt signals act through the Frizzled and RYK receptors during Drosophila salivary gland migration. Development 134(11): 2017-25. Medline abstract: 17507403

Heberlein, U., Borod, E. R. and Chanut, F. A. (1998). Dorsoventral patterning in the Drosophila retina by wingless. 125(4): 567-577. PubMed Citation: 9435278

Hogan, J., Valentine, M., Cox, C., Doyle, K. and Collier, S. (2011). Two frizzled planar cell polarity signals in the Drosophila wing are differentially organized by the Fat/Dachsous pathway. PLoS Genet. 7(2): e1001305. PubMed Citation: 21379328

Hua, Z. L., Chang, H., Wang, Y., Smallwood, P. M. and Nathans, J. (2014). Partial interchangeability of Fz3 and Fz6 in tissue polarity signaling for epithelial orientation and axon growth and guidance. Development 141: 3944-3954. PubMed ID: 25294940

Jarman, A.P. (1996). Epithelial polarity in the Drosophila compound eye: eyes left or right. Trends in Genetics 12: 121-123. PubMed Citation: 8901412

Klingensmith, J., Nusse R., and Perrimon, N. (1994). The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal. Genes Dev 8: 118-30. PubMed Citation: 8288125

Janda, C. Y., et al. (2017). Surrogate Wnt agonists that phenocopy canonical Wnt and beta-catenin signalling. Nature 545(7653): 234-237. PubMed ID: 28467818

Jenny, A., et al. (2005). Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding. Nat. Cell Biol. 7: 691-697. PubMed citation: 15937478

Jones, K.H., Liu, J. and Adler, P.N. (1996). Molecular analysis of EMS-induced frizzled mutations in Drosophila melanogaster. Genetics 142: 205-215. PubMed Citation: 8770598

Katanaev, V. L., Ponzielli, R., Semeriva, M. and Tomlinson, A. (2005). Trimeric G protein-dependent Frizzled signaling in Drosophila. Cell 120: 111-122. 15652486

Katanaev, V. L., Tomlinson, A. (2006). Dual roles for the trimeric G protein Go in asymmetric cell division in Drosophila. Proc. Natl. Acad. Sci. 103: 6524-6529. 16617104

Kennerdell, J. R. and Carthew, R. W. (1998). Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the Wingless pathway. Cell 95: 1017-1026. PubMed Citation: 9875855

Klein, T. J., Jenny, A., Djiane, A. and Mlodzik, M. (2006). CKIε/discs overgrown promotes both Wnt-Fz/β-catenin and Fz/PCP signaling in Drosophila. Curr. Biol. 16(13): 1337-43. 16824922

Krasnow, R.E. and Adler, P.N. (1994). A single frizzled protein has a dual function on tissue polarity. Development 120: 1883-1893. PubMed Citation: 7924994

Krasnow, R. E., Wong, L.L. and Adler, P. N. (1995). dishevelled is a component of the frizzled signaling pathway in Drosophila. Development 121: 4095-4102. PubMed Citation: 8575310

Lawrence, P. A., Casal, J. and Struhl, G. (2004). Cell interactions and planar polarity in the abdominal epidermis of Drosophila. Development 131: 4651-4664. 15329345

Lecourtois, M., et al. (2001). Wingless capture by Frizzled and Frizzled2 in Drosophila embryos. Dev. Bio. 235: 467-475. 11437451

Lee, H. and Adler, P. N. (2002). The function of the frizzled pathway in the Drosophila wing is dependent on inturned and fuzzy. Genetics 160: 1535-1547. 11973308

Matakatsu, H. and Blair, S. S. (2004). Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing. Development 131: 3785-3794. PubMed Citation: 15240556

Mayr, T., et al. (1997). Fritz: a secreted frizzled-related protein that inhibits Wnt activity. Mech. Dev. 63 (1): 109-125. PubMed Citation: 9178261

Moline, M. M., Dierick, H. A., Southern, C. and Bejsovec, A. (2000). Non-equivalent roles of Drosophila Frizzled and Dfrizzled2 in embryonic Wingless signal transduction. Curr. Biol. 10: 1127-1130. 10996794

Ng, J. (2012). Wnt/PCP proteins regulate stereotyped axon branch extension in Drosophila. Development 139(1): 165-77. PubMed Citation: 22147954

Pan, J., You, Y., Huang, T. and Brody, S. L. (2007). RhoA-mediated apical actin enrichment is required for ciliogenesis and promoted by Foxj1. J Cell Sci 120: 1868-1876. PubMed ID: 17488776

Park, T. J., Haigo, S. L. and Wallingford, J. B. (2006). Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling. Nat Genet 38: 303-311. PubMed ID: 16493421

Park, W.J., Liu, J. and Adler, P.N. (1994). The frizzled gene of Drosophila encodes a membrane protein with an odd number of transmembrane domains. Mech Dev. 45: 127-137. PubMed Citation: 8199049

Povelones, M., Howes, R., Fish, M. and Nusse, R. (2005a). Genetic evidence that Drosophila frizzled controls planar cell polarity and Armadillo signaling by a common mechanism. Genetics 171(4): 1643-54. 16085697

Povelones, M. and Nusse, R. (2005b). The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling. EMBO J. 24(19): 3493-503. 16163385

Price, M. H., et al. (2006). Cytoskeletal dynamics and cell signaling during planar polarity establishment in the Drosophila embryonic denticle. J. Cell Sci. 119: 403-415. 16418222

Rajasekharan, S., et al. (2009). Netrin 1 and Dcc regulate oligodendrocyte process branching and membrane extension via Fyn and RhoA. Development 136(3): 415-26. PubMed Citation: 19141671

Rasmussen, J. T., et al. (2001). Regulation of eye development by frizzled signaling in Xenopus. Proc. Natl. Acad. Sci. Vol. 98: 3861-3866. 11274406

Rehn, M. and Pihlajaniemi, T. (1995). Identification of three N terminal ends of type XVIII collagen chains and tissue-specific differences in the expression of the corresponding transcripts. The longest form contains a novel motif homologous to rat and Drosophila frizzled proteins. J.Biol. Chem. 270: 4705-11. PubMed Citation: 7876242

Reifegerste, R., Ma, C. and Moses, K. (1997). A polarity field is established early in the development of the Drosophila compound eye. Mech. Dev. 68(1-2): 69-79. PubMed Citation: 9431805

Roegiers, F., et al. (2001). Two types of asymmetric divisions in the Drosophila sensory organ precursor cell lineage. Nature Cell Bio. 3: 58-67 . 11146627

Rothbacher, U., et al. (2000). Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis. EMBO J. 19: 1010-1022. PubMed Citation: 10698942

Sawa, H., Lobel, L., and Horvitz, H. R. (1996). The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein similar to the Drosophila frizzled protein. Genes Dev 10 (17): 2189-2197. PubMed Citation: 8804313

Schlesinger, A., et al. (1999). Wnt pathway components orient a mitotic spindle in the early Caenorhabditis elegans embryo without requiring gene transcription in the responding cell. Genes Dev. 13: 2028-2038. PubMed Citation: 10444600

Schwarz-Romond, T., et al. (2002). The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the β-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling. Genes Dev. 16: 2073-2084. PubMed citation: 12183362

Shi, D. L., Goisset, C. and Boucaut, J. C. (1998). Expression of Xfz3, a Xenopus frizzled family member, is restricted to the early nervous system. Mech. Dev. 70: 35-47. PubMed Citation: 9510023

Shimada, Y., et al. (2001). Asymmetric colocalization of Flamingo, a seven-pass transmembrane cadherin, and Dishevelled in planar cell polarization. Cur. Biol. 11: 859-863. 11516647

Shimada, Y., Yonemura, S., Ohkura, H., Strutt, D. and Uemura, T. (2006). Polarized transport of Frizzled along the planar microtubule arrays in Drosophila wing epithelium. Dev. Cell 10(2): 209-22. 16459300

Shimizu, K., Sato, M. and Tabata, T. (2011). The Wnt5/planar cell polarity pathway regulates axonal development of the Drosophila mushroom body neuron. J. Neurosci. 31: 4944-4954. PubMed Citation: 21451033

Shulman, J. M., Perrimon, N. and Axelrod, J. D. (1998). Frizzled signaling and the developmental control of cell polarity. Trends Genet. 14: 452-458. PubMed Citation: 9825673

Simons, M. et al. (2005). Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways. Nat. Genet. 37: 537-543. PubMed citation: 15852005

Song, H., Hu, J., Chen, W., Elliott, G., Andre, P., Gao, B. and Yang, Y. (2010). Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning. Nature 466: 378-382. PubMed ID: 20562861

Sotillos, S., et al. (2004). DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila. J. Cell Biol. 166: 549-557. 15302858

Srahna, M., Leyssen, M., Choi, C. M., Fradkin, L. G., Noordermeer, J. N. and Hassan, B. A. (2006). A signaling network for patterning of neuronal connectivity in the Drosophila brain. PLoS Biol. 4(11): e348. Medline abstract: 17032066

Strapps, W. R. and Tomlinson, A. (2001). Transducing properties of Drosophila Frizzled proteins. Development 128: 4829-4835. 11731462

Struhl, G., Casal, J. and Lawrence, P. A. (2012). Dissecting the molecular bridges that mediate the function of Frizzled in planar cell polarity. Development 139: 3665-3674. PubMed ID: 22949620

Strutt, D. I., Weber. U., and Mlodzik, M. (1997). The role of RhoA in tissue polarity and Frizzled signalling. Nature 387 (6630): 292-295. PubMed Citation: 9153394

Strutt, D. I. (2001). Asymmetric localization of Frizzled and the establishment of cell polarity in the Drosophila wing. Molec. Cell 367-375. 11239465

Strutt, H. and Strutt, D. (2002). Nonautonomous planar polarity patterning in Drosophila: Dishevelled-independent functions of Frizzled. Dev. Cell 3: 851-863. 12479810

Strutt, D., Johnson, R., Cooper, K. and Bray, S. (2002). Asymmetric localization of Frizzled and the determination of Notch-dependent cell fate in the Drosophila eye. Curr. Biol. 12: 813-824. 12015117

Strutt, H. and Strutt, D. (2003). EGF signaling and ommatidial rotation in the Drosophila eye. Curr. Biol. 13: 1451-1457. 12932331

Strutt, D. and Warrington, S. J. (2008). Planar polarity genes in the Drosophila wing regulate the localisation of the FH3-domain protein Multiple Wing Hairs to control the site of hair production. Development 135(18): 3103-11. PubMed Citation: 18701542

Strutt, H. and Strutt, D. (2009). Differential stability of flamingo protein complexes underlies the establishment of planar polarity. Curr. Biol. 18(20): 1555-64. PubMed Citation: 18804371

Strutt, H., Warrington, S. J. and Strutt, D. (2011). Dynamics of core planar polarity protein turnover and stable assembly into discrete membrane subdomains. Dev. Cell 20: 511-525. PubMed Citation: 21497763

Tall, G. G., Krumins, A. M. and Gilman, A. G. (2003). Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor. J Biol Chem 278: 8356-8362. PubMed ID: 12509430

Taylor J., et al. (1998). Van Gogh: A new Drosophila tissue polarity gene. Genetics 150(1): 199-210. PubMed Citation: 9725839

Tomlinson, A., Strapps, W. R. and Heemskerk, J. (1997). Linking Frizzled and Wnt signaling in Drosophila development. Development 124(22): 4515-4521. PubMed Citation: 9409669

Tomlinson, A. and Struhl, G. (1999). Decoding vectorial information from a gradient: sequential roles of the receptors Frizzled and Notch in establishing planar polarity in the Drosophila eye. Development 126: 5725-5738. PubMed Citation: 10572048

Tree, D. R. P., et al. (2002). Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling. Cell 109: 371-381. 12015986

Turner, C. M. and Adler, P. N. (1998). Distinct roles for the actin and microtubule cytoskeletons in the morphogenesis of epidermal hairs during wing development in Drosophila. Mech. Dev. 70: 181-192. PubMed Citation: 9510034

Usui, T., et al. (1999). Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled. Cell 98(5): 585-95. PubMed Citation: 10490098

Wagner, U., et al. (1997). Overexpression of the mouse dishevelled-1 protein inhibits GSK-3beta-mediated phosphorylation of tau in transfected mammalian cells. FEBS Lett. 411: 369-372. PubMed Citation: 9271238

Wang, Y., et al. (1996). A large family of putative receptors homologous to the product of the Drosophila tissue polarity gene frizzled. J. Biol. Chem. 271: 4468-76. PubMed Citation: 8626800

Wang, Y., Yan, J., Lee, H., Lu, Q. and Adler, P. N. (2014). The proteins encoded by the Drosophila Planar Polarity Effector genes inturned, fuzzy and fritz interact physically and can re-pattern the accumulation of 'upstream' planar cell polarity proteins. Dev Biol 394(1):156-69. PubMed ID: 25072625

Warrington, S. J., Strutt, H. and Strutt, D. (2013). The Frizzled-dependent planar polarity pathway locally promotes E-cadherin turnover via recruitment of RhoGEF2. Development 140: 1045-1054. PubMed ID: 23364328

Weber, U., Paricio, N. and Mlodzik, M. (2000). Jun mediates Frizzled-induced R3/R4 cell fate distinction and planar polarity determination in the Drosophila eye. Development 127: 3619-3629. PubMed Citation: 10903185

Weber, U., Pataki, C., Mihaly, J. and Mlodzik, M. (2008). Combinatorial signaling by the Frizzled/PCP and Egfr pathways during planar cell polarity establishment in the Drosophila eye. Dev. Biol. 316(1): 110-23. PubMed Citation: 18291359

Wolff, T. and Rubin, G. M. (1998). Strabismus, a novel gene that regulates tissue polarity and cell fate decisions in Drosophila. Development 125(6): 1149-1159. PubMed Citation: 9463361

Wong, L. L. and Adler, P. N. (1993). Tissue polarity genes of Drosophila regulate the subcellular location for prehair initiation in pupal wing cells. J. Cell Biol. 123: 209-221. PubMed Citation: 8408199

Wu, J., Klein, T. J. and Mlodzik, M. (2004). Subcellular localization of frizzled receptors, mediated by their cytoplasmic tails, regulates signaling pathway specificity. PLoS Biol. 2: e158. 15252441

Wu, J., Jenny, A., Mirkovic, I. and Mlodzik, M. (2008a). Frizzled-Dishevelled signaling specificity outcome can be modulated by Diego in Drosophila. Mech. Dev. 125: 30-42. PubMed citation: 18065209

Wu, J. and Mlodzik, M. (2008b). The Frizzled extracellular domain is a ligand for Van Gogh/Stbm during nonautonomous planar cell polarity signaling. Dev. Cell 15: 462-469. PubMed Citation: 18804440

Wu, J. and Mlodzik, M. (2008). The frizzled extracellular domain is a ligand for Van Gogh/Stbm during nonautonomous planar cell polarity signaling. Dev. Cell 15(3): 462-9. PubMed Citation: 18804440

Wu, J., Roman, A. C., Carvajal-Gonzalez, J. M., Mlodzik, M. (2013) Wg and Wnt4 provide long-range directional input to planar cell polarity orientation in Drosophila. Nat Cell Biol 15: 1045-1055. PubMed ID: 23912125

Yang, C.-h., Axelrod, J. D. and Simon, M. A. (2002). Regulation of Frizzled by Fat-like cadherins during planar polarity signaling in the Drosophila compound eye. Cell 108: 675-688. 11893338

Zhang, J. and Carthew, R. W. (1998). Interactions between Wingless and DFz2 during Drosophila wing development. Development 125(16): 3075-3085. PubMed Citation: 9671581

Zhao, Z., Lee, C., Baldini, A. and Caskey, C.T. (1995). A human homologue of the Drosophila polarity gene frizzled has been identified and mapped to 17q21.1. Genomics 27: 370-373. PubMed Citation: 7558010

Zheng, L., Zhang, J. and Carthew, R. W. (1995). frizzled regulates mirror-symmetric pattern formation in the Drosophila eye. Development 121: 3045-3055. PubMed Citation: 7555730

frizzled: Biological Overview | Evolutionary Homologs | Regulation | Developmental Biology | Effects of Mutation

date revised: 18 June 2017

Home page: The Interactive Fly © 1997 Thomas B. Brody, Ph.D.

The Interactive Fly resides on the
Society for Developmental Biology's Web server.