thickveins


REFERENCES

Adachi-Yamada, T., et al. (1999). p38 mitogen-activated protein kinase can be involved in transforming growth factor beta superfamily signal transduction in Drosophila wing morphogenesis. Mol. Cell. Biol. 19(3): 2322-9. PubMed ID: 10022918

Akiyama, T., et al. (2008). Dally regulates Dpp morphogen gradient formation by stabilizing Dpp on the cell surface. Dev. Biol. 313(1): 408-19. PubMed ID: 18054902

Affolter, M., Nellen, D., Nussbaumer, U. and Basler, K., (1994). Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGF beta homologs during Drosophila embryogenesis. Development 120: 3105-3117. PubMed ID: 7720555

Ahn, K., et al. (2001). BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb. Development 128: 4449-4461. PubMed ID: 11714671

Akiyama, S., et al. (1997). Constitutively active BMP type I receptors transduce BMP-2 signals without the ligand in C2C12 myoblasts. Exp. Cell Res. 235(2): 362-369. PubMed ID: 9299160

Andl, T., et al. (2004), Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development. Development 131: 2257-2268. PubMed ID: 15102710

Armes, N. A. and Smith, J. C. (1997). The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm-inducing signals during early Xenopus development but do not co-operate to establish thresholds. Development 124(19): 3797-3804. PubMed ID: 9367435

Arquier, N., et al. (2001). The Drosophila tumor suppressor gene lethal(2)giant larvae is required for the emission of the Decapentaplegic signal. Development 128: 2209-2220. PubMed ID: 11493541

Atfi, A., et al. (1997). Evidence for a role of Rho-like GTPases and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) in transforming growth factor beta-mediated signaling. J. Biol. Chem. 272: 1429-1432. PubMed ID: 8999807

Ayyaz, A., Li, H. and Jasper, H. (2015). Haemocytes control stem cell activity in the Drosophila intestine. Nat Cell Biol 17: 736-748. PubMed ID: 26005834

Azpiazu, N. and Morata, G. (2000). Function and regulation of homothorax in the wing imaginal disc of Drosophila. Development 127: 2685-2693. PubMed ID: 10821766

Bangi, E. and Wharton, K. (2006a). Dpp and Gbb exhibit different effective ranges in the establishment of the BMP activity gradient critical for Drosophila wing patterning. Dev. Biol. 295(1): 178-93. PubMed ID: 16643887

Bangi, E. and Wharton, K. (2006b). Dual function of the Drosophila Alk1/Alk2 ortholog Saxophone shapes the Bmp activity gradient in the wing imaginal disc. Development 133(17): 3295-303. PubMed ID: 16887821

Bartoszewski, S., et al. (2004). Drosophila p24 homologues eclair and baiser are necessary for the activity of the maternally expressed Tkv receptor during early embryogenesis. Mech. Dev. 121: 1259-1273 . PubMed ID: 15327786

Baumann, A., et al. (2010). Paralogous genes involved in juvenile hormone action in Drosophila melanogaster. Genetics 185: 1327-1336. PubMed ID: 20498297

Baur, S. T., Mai, J. J. and Dymecki, S. M. (2000). Combinatorial signaling through BMP receptor IB and GDF5: shaping of the distal mouse limb and the genetics of distal limb diversity. Development 127: 605-619. PubMed ID: 10631181

Bennett, D., Szoor, B. and Alphey, L. (1999). The chaperone-like properties of mammalian Inhibitor-2 are conserved in a Drosophila homologue. Biochemistry 38: 16276-16282. PubMed ID: 10587451

Bennett, D. and Alphey, L. (2002). PP1 binds Sara and negatively regulates Dpp signaling in Drosophila melanogaster. Nature Genetics 31(4): 419-423. PubMed ID: 12134149

Bennett, D., et al. (2003). Ectopic expression of inhibitors of protein Phosphatase Type 1 (PP1) can be used to analyze roles of PP1 in Drosophila development. Genetics 164: 235-245. PubMed ID: 12750335

Bilodeau, P. S., Urbanowski, J. L., Winistorfer, S. C. and Piper, R. C. ( 2002). The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting. Nat. Cell Biol. 4: 534-539. PubMed ID: 12055639

Blanchard, G. B., Murugesu, S., Adams, R. J., Martinez-Arias, A. and Gorfinkiel, N. (2010). Cytoskeletal dynamics and supracellular organisation of cell shape fluctuations during dorsal closure. Development 137(16): 2743-52. PubMed ID: 20663818

Boube, M., Llimargas, M. and Casanova, J. (2000). Cross-regulatory interactions among tracheal genes support a co-operative model for the induction of tracheal fates in the Drosophila embryo. Mech. Dev. 91: 271-278. PubMed ID: 10704851

Bradley, P. L., Myat, M. M., Comeaux, C. A. and Andrew, D. J. (2003). Posterior migration of the salivary gland requires an intact visceral mesoderm and integrin function. Dev. Biol. 257: 249-262. PubMed ID: 12729556

Brummel, T. J., et al. (1994). Characterization and relationship of Dpp receptors encoded by the saxophone and thick veins genes in Drosophila. Cell 78: 251-261. PubMed ID: 8044839

Bryant, Z., et al. (1999). Characterization of differentially expressed genes in purified Drosophila follicle cells: toward a general strategy for cell type-specific developmental analysis. Proc. Natl. Acad. Sci. 96(10): 5559-64. PubMed ID: 10318923

Bunt, S., Hooley, C., Hu, N., Scahill, C., Weavers, H. and Skaer, H. (2010). Hemocyte-secreted type IV collagen enhances BMP signaling to guide renal tubule morphogenesis in Drosophila. Dev. Cell 19(2): 296-306. PubMed ID: 20708591

Burke, R. and Basler, K. (1996a). Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing. Development 122: 2261-69. PubMed ID: 8681806

Burke, R. and Basler, K. (1996b). Hedgehog-dependent patterning in the Drosophila eye can occur in the absence of Dpp signaling. Dev. Biol. 179 (2): 360-368. PubMed ID: 8903352

Chang, C., et al. (1997). A Xenopus type I activin receptor mediates mesodermal but not neural specification during embryogenesis. Development 124: 827-837. PubMed ID: 9043064

Chen, D., et al. (1998). Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages. J. Cell Biol. 142(1): 295-305. PubMed ID: 9660882

Chen, Y. G., Liu, F. and Massague, J. (1997). Mechanism of TGFbeta receptor inhibition by FKBP12. EMBO J. 16(13): 3866-3876. PubMed ID: 9233797

Chen, Y., et al. (1998). A genetic screen for modifiers of Drosophila decapentaplegic signaling identifies mutations in punt, Mothers against dpp and the BMP-7 homologue, 60A. Development 125(9): 1759-1768. PubMed ID: 9521913

Conley, C. A., et al. (2000). Crossveinless 2 contains cysteine-rich domains and is required for high levels of BMP-like activity during the formation of the cross veins in Drosophila. Development 127: 3947-3959. PubMed ID: 10952893

Crickmore, M. A. and Mann, R. S. (2006). Hox control of organ size by regulation of morphogen production and mobility. Science 313(5783): 63-8. PubMed ID: 16741075

Cullen, P. J. (2008). Endosomal sorting and signalling: an emerging role for sorting nexins. Nat. Rev. Mol. Cell Biol. 9: 574-582. PubMed ID: 18523436

Curtis, B. J., Zraly, C. B. and Dingwall, A. K. (2013). Drosophila LSD1-CoREST demethylase complex regulates DPP/TGFbeta signaling during wing development. Genesis 51: 16-31. Pubmed: 22965777

de Celis, J. F. (1997). Expression and function of decapentaplegic and thick veins during the differentiation of the veins in the Drosophila wing. Development 124: 1007-1018. PubMed ID: 9056776

de Sousa Lopes, S. M C., et al. (2004). BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo. Genes Dev. 18: 1838-1849. PubMed ID: 15289457

del Alamo Rodriguez, D., Terriente Felix, J., Diaz-Benjumea, F. J. (2004). The role of the T-box gene optomotor-blind in patterning the Drosophila wing. Dev. Biol. 268(2): 481-92. PubMed ID: 15063183

Denzel, A., Otto, F., Girod, A., Pepperkok, R., Watson, R., Rosewell, I. et al., (2000). The p24 family member p23 is required for early embryonic development. Curr. Biol. 10: 55-58. PubMed ID: 10660306

Dewulf. N., et al. (1995). Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis. Endocrinology 136(6): 2652-2663. PubMed ID: 7750489

Dorfman, R. and Shilo, B.-Z. (2001). Biphasic activation of the BMP pathway patterns the Drosophila embryonic dorsal region. Development 128: 965-972. PubMed ID: 11222150

Dyson, S. and Gurdon, J. B. (1998). The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors. Cell 93(4): 557-568. PubMed ID: 9604931

Feng, X. H. and Derynck, R. (1997). A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity. EMBO J. 16(13): 3912-3923. PubMed ID: 9233801

Fernández, B. G., Ariasc, A. M. and Jacinto, A. (2007). Dpp signalling orchestrates dorsal closure by regulating cell shape changes both in the amnioserosa and in the epidermis. Mech. Dev. 124: 884-897. PubMed ID: 17950580

Fernandes, M., et al. (2007). Mutations in the BMP pathway in mice support the existence of two molecular classes of holoprosencephaly. Development 134: 3789-3794. PubMed ID: 17913790

Franch-Marro, X. and Casanova, J. (2000). The alternative migratory pathways of the Drosophila tracheal cells are associated with distinct subsets of mesodermal cells. Dev. Biol. 227: 80-90. PubMed ID: 11076678

Funakoshi, Y., Minami, M. and Tabata, T. (2001). mtv shapes the activity gradient of the Dpp morphogen through regulation of thickveins. Development 128: 67-74. PubMed ID: 11092812

Garamszegi, N., et al. (2001). Transforming growth factor receptor signaling and endocytosis are linked through a COOH terminal activation motif in the type I receptor. Mol. Biol. Cell 12: 2881-2893. PubMed ID: 11553725

Garcia-Bellido, A. and de Celis, J. F. (1992). Developmental genetics of the venation pattern of Drosophila. A. Rev. Genet. 1992 26: 277-304. PubMed ID: 1482114

Gibert, J. M., Marcellini, S., David, J. R., Schlotterer, C. and Simpson, P. (2005). A major bristle QTL from a selected population of Drosophila uncovers the zinc-finger transcription factor Poils-au-dos, a repressor of achaete-scute. Dev. Biol. 288(1): 194-205. PubMed ID: 16216235

Gleason, R. J., Vora, M., Li, Y., Kane, N. S., Liao, K. and Padgett, R. W. (2017). C. elegans SMA-10 regulates BMP receptor trafficking. PLoS One 12(7): e0180681. PubMed ID: 28704415

Gonzalez-Gaitan, G. and Jackle, H. (1999). The range of spalt-activating Dpp signalling is reduced in endocytosis- defective Drosophila wing discs. Mech. Dev. 87: 143-151. PubMed ID: 10495278

Gorfinkiel N., Blanchard G. B., Adams R. J. and Martinez-Arias A. (2009). Mechanical control of global cell behaviour during dorsal closure in Drosophila. Development 136: 1889-1898. PubMed ID: 1940366

Griswold-Prenner, I., et al., (1998). Physical and functional interactions between type I transforming growth factor beta receptors and Balpha, a WD-40 repeat subunit of phosphatase 2A. Mol. Cell. Biol. 18(11): 6595-604

Gu, Z., et al. (1998). The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse. Genes Dev. 12(6): 844-857. PubMed ID: 9512518

Gui, J., Huang, Y. and Shimmi, O. (2016). Scribbled optimizes BMP signaling through its receptor internalization to the Rab5 endosome and promote robust epithelial morphogenesis. PLoS Genet 12: e1006424. PubMed ID: 27814354

Gunther, C. V., Georgi, L. L. and Riddle, D. L. (2000). A Caenorhabditis elegans type I TGFbeta receptor can function in the absence of type II kinase to promote larval development. Development 127: 3337-3347. PubMed ID: 10887089

Han, Z. S., et al. (1998). A conserved p38 mitogen-activated protein kinase pathway regulates Drosophila immunity gene expression. Mol. Cell. Biol. 18(6): 3527-39. PubMed ID: 9584193

Hatton-Ellis, E., Ainsworth, C., Sushama, Y., Wan, S., VijayRaghavan, K. and Skaer, H. (2007). Genetic regulation of patterned tubular branching in Drosophila. Proc. Natl. Acad. Sci. 104: 169-174. PubMed ID: 17190812

Henderson, K. D., Isaac, D. D. and Andrew, D. J. (1999). Cell fate specification in the Drosophila salivary gland: the integration of homeotic gene function with the DPP signaling cascade. Dev. Biol. 205(1): 10-21. PubMed ID: 9882494

Hébert, J. M., Mishina, Y. and McConnell, S. K. (2002). BMP signaling is required locally to pattern the dorsal telencephalic midline. Neuron 35: 1029-1041. PubMed ID: 12354394

Hsiung, F., et al. (2005). Dependence of Drosophila wing imaginal disc cytonemes on Decapentaplegic. Nature 437: 560-563. PubMed ID: 16177792

Huang, J., et al. (2011). DPP-mediated TGFβ signaling regulates juvenile hormone biosynthesis by activating the expression of juvenile hormone acid methyltransferase. Development 138(11): 2283-91. PubMed ID: 21558376

Huse, M., et al. (2001). The TGFß receptor activation process: an inhibitor- to substrate-binding switch. Molec. Cell 8: 671-682. PubMed ID: 11583628

Ikeda, T., et al. (1996). Cloning of rat type I receptor cDNA for bone morphogenetic protein-2 and bone morphogenetic protein-4, and the localization compared with that of the ligands. Dev. Dyn. 206(3): 318-329. PubMed ID: 8896987

Inaba, M., Buszczak, M. and Yamashita, Y.M. (2015). Nanotubes mediate niche-stem-cell signalling in the Drosophila testis. Nature 523(7560):329-32.. PubMed ID: 26131929

Jack, J. and Myette, G. (1999). Mutations that alter the morphology of the Malpighian tubules in Drosophila. Dev. Genes Evol. 209: 546-554. PubMed ID: 10502111

Jazwinska, A., et al. (1999). The Drosophila gene brinker reveals a novel mechanism of Dpp target gene regulation. Cell 96(4): 563-73. PubMed ID: 10052458

Jékely, G. and Rørth, P. (2003). Hrs mediates downregulation of multiple signalling receptors in Drosophila. EMBO reports 4: 1163-1168. PubMed ID: 14608370

Kang, M. J., Hansen, T. J., Mickiewicz, M., Kaczynski, T. J., Fye, S. and Gunawardena, S. (2014). Disruption of axonal transport perturbs Bone Morphogenetic Protein (BMP) - signaling and contributes to synaptic abnormalities in rwo neurodegenerative diseases. PLoS One 9: e104617. PubMed ID: 25127478

Kawakami, Y., et al. (1996). BMP signaling during bone pattern determination in the developing limb. Development 122, 3557-3566

Khalsa, O., et al. (1998). TGF-beta/BMP superfamily members, Gbb-60A and Dpp, cooperate to provide pattern information and establish cell identity in the Drosophila wing. Development 125: 2723-2734. PubMed ID: 9636086

Khodosh R., Augsburger A., Schwarz T. L. and Garrity P. A. (2006). Bchs, a BEACH domain protein, antagonizes Rab11 in synapse morphogenesis and other developmental events. Development 133: 4655-4665. PubMed ID: 17079274

Kim, S., Wairkar, Y. P., Daniels, R. W. and DiAntonio, A. (2010), The novel endosomal membrane protein Ema interacts with the class C Vps-HOPS complex to promote endosomal maturation. J. Cell Biol. 188(5): 717-34. PubMed ID: 20194640

Kirilly, D., Spana, E. P., Perrimon, N., Padgett, R. W. and Xie, T. (2005). BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary.Dev. Cell 9(5): 651-62. PubMed ID: 16256740

Kirsch, T., Nickel, J. and Sebald, W. (2000). BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II. EMBO J. 19: 3314-3324. PubMed ID: 10880444

Klämbt, C. (2009). Modes and regulation of glial migration in vertebrates and invertebrates. Nat. Rev. Neurosci. 10: 769-779. PubMed ID: 19773781

Koenig, B. B., et al. (1994). Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells. Mol. Cell. Biol. 14(9): 5961-5974. PubMed ID: 8065329

Komada, M., Masaki, R., Yamamoto, A. and Kitamura, N. (1997). Hrs, a tyrosine kinase substrate with a conserved double zinc finger domain, is localized to the cytoplasmic surface of early endosomes. J. Biol. Chem. 272: 20538-20544. PubMed ID: 9252367

Kretzschmar, M., et al. (1997). The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase. Genes Dev. 11: 984-995. PubMed ID: 9136927

Krishna, S., Maduzia, L. L. and Padgett, R. W. (1999). Specificity of TGFbeta signaling is conferred by distinct type I receptors and their associated SMAD proteins in Caenorhabditis elegans. Development 126(2): 251-260. PubMed ID: 9847239

Kubota, K., et al. (2000). EGF receptor attenuates Dpp signaling and helps to distinguish the wing and leg cell fates in Drosophila. Development 127: 3769-3776. PubMed ID: 10934021

Lebrun, J. J. and Vale, W. W. (1997). Activin and Inhibin Have Antagonistic Effects on Ligand-Dependent Heteromerization of the Type I and Type II Activin Receptors and Human Erythroid Differentiation. Mol. Cell. Biol. 17: 1682-91. PubMed ID: 9032295

Lecuit, T. and Cohen, S. M. (1998). Dpp receptor levels contribute to shaping the Dpp morphogen gradient in the Drosophila wing imaginal disc. Development 125: 4901-4907. PubMed ID: 9811574

Lee-Hoeflich, S. T., Zhao, X., Mehra, A., Attisano, L.T. (2005). The Drosophila type II receptor, Wishful thinking, binds BMP and myoglianin to activate multiple TGFbeta family signaling pathways FEBS Lett. 579: 4615-21. PubMed ID: 16098524

Leiblich, A., Marsden, L., Gandy, C., Corrigan, L., Jenkins, R., Hamdy, F. and Wilson, C. (2012). Bone morphogenetic protein- and mating-dependent secretory cell growth and migration in the Drosophila accessory gland. Proc Natl Acad Sci U S A 109: 19292-19297. PubMed ID: 23129615

Letsou, A., et al. (1995). Drosophila Dpp signaling is mediated by the punt gene product: a dual ligand-binding type II receptor of the TGF beta receptor family. Cell 80: 899-908. PubMed ID: 7697720

Lia, J. and Li, W. X. (2003). Drosophila gain-of-function mutant RTK torso triggers ectopic Dpp and STAT signaling. Genetics 164: 247-258. PubMed ID: 12750336

Liu, F., et al. (1995). Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs. Mol. Cell. Biol. 15(7): 3479-3486. PubMed ID: 7791754

Liu, J., Wilson, S. and Reh, T. (2003). BMP receptor 1b is required for axon guidance and cell survival in the developing retina. Dev. Bio. 256: 34-47. PubMed ID: 12654290

Liu, W., et al. (2005). Distinct functions for Bmp signaling in lip and palate fusion in mice. Development 132: 1453-1461. PubMed ID: 15716346

Liu, Z., Huang, Y., Hu, W., Huang, S., Wang, Q., Han, J. and Zhang, Y. Q. (2014). dAcsl, the Drosophila Ortholog of Acyl-CoA Synthetase Long-Chain Family Member 3 and 4, Inhibits Synapse Growth by Attenuating Bone Morphogenetic Protein Signaling via Endocytic Recycling. J Neurosci 34: 2785-2796. PubMed ID: 24553921

Llimargas, M. and Casanova, J. (1997). ventral veinless, a POU domain transcription factor, regulates different transduction pathways required for tracheal branching in Drosophila. Development 124(17): 3273-3281. PubMed ID: 9310322

Llimargas, M. and Casanova, J. (1999). EGF signalling regulates cell invagination as well as cell migration during formation of tracheal system in Drosophila. Dev. Genes Evol. 209: 174-179. PubMed ID: 10079360

Lloyd, T. E., Atkinson, R., Wu, M. N., Zhou, Y., Pennetta, G. and Bellen, H. J. ( 2002). Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila. Cell 108: 261-269. PubMed ID: 11832215

Macias-Silva, M., et al. (1998). Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2. J. Biol. Chem. 273(40): 25628-36. PubMed ID: 9748228

Mantrova, E. Y., Schulz, R. A. and Hsu, T. (1999). Oogenic function of the myogenic factor D-MEF2: Negative regulation of the Decapentaplegic receptor gene thick veins. Proc. Natl. Acad. Sci. 96: 11889-11894. PubMed ID: 10518546

Martín-Castellanos, C. and Edgar, B. A. (2002). A characterization of the effects of Dpp signaling on cell growth and proliferation in the Drosophila wing. Development 129: 1003-1013. PubMed ID: 11861483

Massagué, J. (1996). TGFß signaling: Receptors, transducers and Mad proteins. Cell 85: 947-950. PubMed ID: 8674122

Maier, E., et al. (2010). Opposing Fgf and Bmp activities regulate the specification of olfactory sensory and respiratory epithelial cell fates. Development 137(10): 1601-11. PubMed ID: 20392740

Mishina, Y., et al. (1995). Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis. Genes Dev. 9(24): 3027-3037. PubMed ID: 8543149

Michel, M., et al. (2011). Local BMP receptor activation at adherens junctions in the Drosophila germline stem cell niche. Nat. Commun. 2: 415. PubMed ID: 21811244

Leiblich, A., Marsden, L., Gandy, C., Corrigan, L., Jenkins, R., Hamdy, F. and Wilson, C. (2012). Bone morphogenetic protein- and mating-dependent secretory cell growth and migration in the Drosophila accessory gland. Proc Natl Acad Sci U S A 109: 19292-19297. PubMed ID: 23129615

Minami, R., Wakabayashi, M., Sugimori, S., Taniguchi, K., Kokuryo, A., Imano, T., Adachi-Yamada, T., Watanabe, N. and Nakagoshi, H. (2012). The homeodomain protein defective proventriculus is essential for male accessory gland development to enhance fecundity in Drosophila. PLoS One 7: e32302. PubMed ID: 22427829

Miura, S. et al. (2000). Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA. Mol. Cell. Biol. 20: 9346-9355. PubMed ID: 11094085

Morikawa, Y., et al. (2009). BMP signaling regulates sympathetic nervous system development through Smad4-dependent and -independent pathways. Development 136(21): 3575-84. PubMed ID: 19793887

Murali, D., et al. (2005). Distinct developmental programs require different levels of Bmp signaling during mouse retinal development. Development 132: 913-923. PubMed ID: 15673568

Nakao, A, et al. (1997). TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4. EMBO J. 16(17): 5353-5362 . PubMed ID: 9311995

Newfeld, S. J., et al. (1997). Mothers against dpp participates in a DPP/TGF-beta responsive serine-threonine kinase signal transduction cascade. Development 124(16): 3167-3176. PubMed ID: 9272957

Nellen, D., Affolter, M. and Basler, K. (1994). Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic. Cell 78: 225-237. PubMed ID: 8044837

Nellen, D., et al. (1996). Direct and long-range action of a DPP morphogen gradient. Cell 85: 357-369. PubMed ID: 22003571

Nguyen, M., et al. (1998). Interpretation of a BMP activity gradient in Drosophila embryos depends on synergistic signaling by two type I receptors, SAX and TKV. Cell 95(4):495-506. PubMed ID: 9827802

Nikaido, M., et al. (1999). In vivo analysis using variants of zebrafish BMPR-IA: range of action and involvement of BMP in ectoderm patterning. Development 126(1): 181-190. PubMed ID: 9834197

Ninov N., Menezes-Cabral S., Prat-Rojo C., Manjon C., Weiss A., Pyrowolakis G., Affolter M. and Martin-Blanco E. (2010). Dpp signaling directs cell motility and invasiveness during epithelial morphogenesis. Curr. Biol. 20: 513-520. PubMed ID: 20226662

Nishitoh, H., et al. (1996). Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5. J. Biol. Chem. 271(35): 21345-21352. PubMed ID: 8702914

Nohno, T., et al. (1995). Identification of a human type II receptor for bone morphogenetic protein-4 that forms differential heteromeric complexes with bone morphogenetic protein type I receptors. J. Biol. Chem. 270(38): 22522-22526. PubMed ID: 7673243

O'Connor-Giles, K. M., Ho, L. L. and Ganetzky, B. (2008). Nervous wreck interacts with thickveins and the endocytic machinery to attenuate retrograde BMP signaling during synaptic growth. Neuron 58(4): 507-18. PubMed ID: 18498733

Oeda E., et al. (1998). Interaction of Drosophila inhibitors of apoptosis with Thick veins, a type I Serine/Threonine kinase receptor for Decapentaplegic. J. Biol. Chem. 273(16): 9353-9356. PubMed ID: 9545255

Onichtchouk, D., et al. (1999). Silencing of TGF-beta signaling by the pseudoreceptor BAMBI. Nature 401(6752): 480-5. PubMed ID: 10519551

Pajni-Underwood, S., et al. (2007). BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling. Development 134: 2359-2368. PubMed ID: 17537800

Panchision, D. M., et al. (2001). Sequential actions of BMP receptors control neural precursor cell production and fate. Genes Dev. 15: 2094-2110. PubMed ID: 11511541

Parker, L., et al., (2002). Functional interaction between NIPP1 and PP1 in Drosophila: consequences of over-expression of NIPP1 in flies and suppression by co-expression of PP1. Biochem. J. 368: 789-797. PubMed ID: 12358598

Penton, A., et al. (1994). Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a Decapentaplegic receptor. Cell 78: 239-250. PubMed ID: 8044838

Penton, A., Selleck, S. B. and Hoffmann, F. M. (1997). Regulation of cell cycle synchronization by decapentaplegic during Drosophila eye development. Science 275(5297): 203-206. PubMed ID: 8985012

Persson, U., et al. (1997). Transforming growth factor (TGF-beta)-specific signaling by chimeric TGF-beta type II receptor with intracellular domain of activin type IIB receptor. J. Biol. Chem. 272(34): 21187-21194. PubMed ID: 9261125

Piper, R. C., Cooper, A. A., Yang, H. and Stevens, T. H. (1995). VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae. J. Cell Biol. 131: 603-617. PubMed ID: 7593183

Polo, S., Sigismund, S., Faretta, M., Guidi, M., Capua, M. R., Bossi, G., Chen, H., De Camilli, P. and Di Fiore, P. P. (2002). A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins. Nature 416: 51-55. PubMed ID: 11919637

Qin, B. Y., et al. (2001). Structural basis of Smad1 activation by receptor kinase phosphorylation. Mol. Cell 8: 1303-1312. PubMed ID: 11779505

Raiborg, C., Bache, K. G., Gillooly, D. J., Madshus, I. H., Stang, E. and Stenmark, H. (2002). Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes. Nature Cell Biol. 4: 394-398. PubMed ID: 11988743

Rao, Y., et al. (2010). Molecular basis for SH3 domain regulation of F-BAR-mediated membrane deformation. Proc. Natl. Acad. Sci. 107: 8213-8218. PubMed ID: 20404169

Rentzsch, F., Zhang, J., Kramer, C., Sebald, W. and Hammerschmidt, M. (2006). Crossveinless 2 is an essential positive feedback regulator of Bmp signaling during zebrafish gastrulation. Development 133: 801-811. PubMed ID: 16439480

Ribeiro, C., Ebner, A. and Affolter, M. (202). In vivo imaging reveals different cellular functions for FGF and Dpp signaling in tracheal branching morphogenesis. Dev. Cell 2: 677-683. PubMed ID: 12015974

Ricos, M. G., et al. (1999). Dcdc42 acts in TGF-beta signaling during Drosophila morphogenesis: distinct roles for the Drac1/JNK and Dcdc42/TGF-beta cascades in cytoskeletal regulation. J. Cell Sci. 112(Pt 8): 1225-1235. PubMed ID: 10085257

Rodal, A. A., et al. (2011). A presynaptic endosomal trafficking pathway controls synaptic growth signaling. J. Cell Biol. 193(1): 201-17. PubMed ID: 21464232

Roy, S., Hsiung, F. and Kornberg, T. B. (2011). Specificity of Drosophila cytonemes for distinct signaling pathways. Science 332(6027): 354-8. PubMed ID: 21493861

Ruberte, E., et al. (1995) An absolute requirement for both the type II and type I receptors, punt and thick veins for dpp sgnaling in vivo. Cell 80: 889-97. PubMed ID: 7697719

Satow, R., Kurisaki, A., Chan, T. C., Hamazaki, T. S. and Asashima, M. (2006). Dullard promotes degradation and dephosphorylation of BMP receptors and is required for neural induction. Dev. Cell 11(6): 763-74. PubMed ID: 17141153

Schwank, G., et al. (2011). Formation of the long range Dpp morphogen gradient. PLoS Biol. 9(7): e1001111. PubMed ID: 21814489

Serpe, M., et al. (2008). The BMP-binding protein Crossveinless 2 is a short-range, concentration-dependent, biphasic modulator of BMP signaling in Drosophila. Dev. Cell 14: 940-953. PubMed ID: 18539121

Shen, J. and Dahmann, C. (2005). The role of Dpp signaling in maintaining the Drosophila anteroposterior compartment boundary. Dev. Biol. 279(1): 31-43. PubMed ID: 15708556

Shin, D., et al. (2007). Bmp and Fgf signaling are essential for liver specification in zebrafish. Development 134: 2041-2050. PubMed ID: 17507405

Shivdasani, A. A. and Ingham, P. W. (2003). Regulation of stem cell maintenance and transit amplifying cell proliferation by TGF-ß signaling in Drosophila spermatogenesis. Curr. Biol. 13: 2065-2072. PubMed ID: 14653996

Silies, M., Yuva-Aydemir, Y., Franzdóttir, S. R. and Klämbt, C. (2010). The eye imaginal disc as a model to study the coordination of neuronal and glial development. Fly (Austin) 4: 71-79. PubMed ID: 20160502

Singer, M. A., et al. (1997). Signaling through both type I DPP receptors is required for anterior-posterior patterning of the entire Drosophila wing. Development 124: 79-89. PubMed ID: 9006069

Smith, R. B., Machamer, J. B., Kim, N. C., Hays, T. S. and Marqués, G.. (2012). Relay of retrograde synaptogenic signals through axonal transport of BMP receptors. J. Cell Sci. [Epub ahead of print]. PubMed ID: 22573823

Solon, J., Kaya-Copur, A., Colombelli, J. and Brunner, D. (2009). Pulsed forces timed by a ratchet-like mechanism drive directed tissue movement during dorsal closure. Cell 137: 1331-1342. PubMed ID: 19563762

Soshnikova, N., et al. (2003). Genetic interaction between Wnt/ß-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb. Genes Dev. 17: 1963-1968. PubMed ID: 12923052

Staehling-Hampton, K., et al. (1994). dpp induces mesodermal gene expression in Drosophila. Nature 372: 783-6. PubMed ID: 7997266

Steneberg, P., Hemphala, J. and Samakovlis, C. (1999). Dpp and Notch specify the fusion cell fate in the dorsal branches of the Drosophila trachea. Mech. Dev. 87: 153-163. PubMed ID: 10495279

Stottmann, R. W., et al. (2004). BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium. Development 131: 2205-2218. PubMed ID: 15073157

Sun, K., Westholm, J. O., Tsurudome, K., Hagen, J. W., Lu, Y., Kohwi, M., Betel, D., Gao, F. B., Haghighi, A. P., Doe, C. Q. and Lai, E. C. (2012). Neurophysiological defects and neuronal gene deregulation in Drosophila mir-124 mutants. PLoS Genet 8: e1002515. Pubmed: 22347817

Sweeney, S. T. and Davis, G. W. (2002). Unrestricted synaptic growth in spinster -- a late endosomal protein implicated in TGF-ß-mediated synaptic growth regulation. Neuron 36: 403-416. PubMed ID: 12408844

Tanimoto, H., et al. (2000). Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs. Molec. Cell 5: 59-71. PubMed ID: 10678169

Thompson, B. J., Mathieu, J., Sung, H. H., Loeser, E., Rorth, P. and Cohen, S. M. (2005). Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila. Dev. Cell 9(5): 711-20. PubMed ID: 16256745

Tsuneizumi, K., et al. (1997). Daughters against dpp modulates dpp organizing activity in Drosophila wing development. Nature 389: 627-631. PubMed ID: 9335506

Varley, J. E., et al. (1998). Expression of a constitutively active type I BMP receptor using a retroviral vector promotes the development of adrenergic cells in neural crest cultures. Dev. Biol. 196(1): 107-118. PubMed ID: 9527884

Vasilyev, A., Liu, L., Mudumana, S., Mongos, S., Lam, P.-Y., Majumdar, A., Zhao, J., Poon, K.-L., Kondrychyn, K., and Drummond, I. (2009). Collective cell migration drives morphogenesis of the kidney nephron. PLoS Biol. 7: e9. PubMed ID: 19127979

Vincent, S., et al. (1997). DPP controls tracheal cell migration along the dorsoventral body axis of the Drosophila embryo. Development 124(14): 2741-2750. PubMed ID: 9226445

Vrailas, A. D. and Moses, K. (2006a). smoothened, thickveins and the genetic control of cell cycle and cell fate in the developing Drosophila eye. Mech. Dev. 123(2): 151-65. PubMed ID: 16412615

Vrailas, A. D., et al. (2006b). smoothened and thickveins regulate Moleskin/Importin 7-mediated MAP kinase signaling in the developing Drosophila eye. Development 133(8): 1485-94. PubMed ID: 16540506

Wada, A., et al. (2007). Specialized extraembryonic cells connect embryonic and extraembryonic epidermis in response to Dpp during dorsal closure in Drosophila. Dev. Biol. 301: 340-349. PubMed ID: 17034783

Wang, K., et al. (2008). Drosophila spichthyin inhibits BMP signaling and regulates synaptic growth and axonal microtubules. Nat. Neurosci. 10: 177-185. PubMed ID: 17220882

Wang, T., et al. (1996). The immunophilin FKBP12 functions as a common inhibitor of the TGFß family type I receptors. Cell 86: 435-444. PubMed ID: 8756725

Wang, X., Harris, R. E., Bayston, L. J. and Ashe, H. L. (2008). Type IV collagens regulate BMP signalling in Drosophila. Nature 455(7209): 72-7. PubMed ID: 18701888

Wen, C. and Greenwald, I. (1999). p24 proteins and quality control of LIN-12 and GLP-1 trafficking in Caenorhabditis elegans. J. Cell Biol. 145: 1165-1175. PubMed ID: 10366590

Wharton, K. A. (1995). How many receptors does it take? Bioessays 17: 13-16. PubMed ID: 7702589

Widmann, T. J. and Dahmann, C. (2009). Dpp signaling promotes the cuboidal-to-columnar shape transition of Drosophila wing disc epithelia by regulating Rho1. J. Cell Sci. 122(Pt 9): 1362-73. PubMed ID: 19366729

Wilson, M. J., Kenny, N. J. and Dearden, P. K. (2014). Components of the dorsal-ventral pathway also contribute to anterior-posterior patterning in honeybee embryos (Apis mellifera). Evodevo 5: 11. PubMed ID: 24620747

Wine-Lee, L., et al. (2004). Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord. Development 131: 5393-5403. PubMed ID: 15469980

Xia, L., et al. (2012). The niche-dependent feedback loop generates a BMP activity gradient to determine the germline stem cell fate. Curr. Biol. 22(6): 515-21. PubMed ID: 22365848

Xia, L., Jia, S., Huang, S., Wang, H., Zhu, Y., Mu, Y., Kan, L., Zheng, W., Wu, D., Li, X., Sun, Q., Meng, A. and Chen, D. (2010). The Fused/Smurf complex controls the fate of Drosophila germline stem cells by generating a gradient BMP response. Cell 143: 978-990. PubMed ID: 21145463

Xie, T., Finelli, A. L. and Padgett, R. W. (1994). The Drosophila saxophone gene: a serine-threonine kinase receptor of the TGF-beta superfamily. Science 263: 1756-9. PubMed ID: 8134837

Xie, T. and Spradling, A. C. (1998). decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary. Cell 94(2): 251-260. PubMed ID: 9695953

Yakoby, N., et al. (2008). Drosophila eggshell is patterned by sequential action of feedforward and feedback loops. Development 135: 343-351. PubMed ID: 18077592

Yamauchi, K., Phan, K. D. and Butler, S. J. (2008). BMP type I receptor complexes have distinct activities mediating cell fate and axon guidance decisions. Development 135: 1119-1128. PubMed ID: 18272594

Yi, S. E., et al. (2000). The type I BMP receptor BMPRIB is required for chondrogenesis in the mouse limb. Development 127: 621-630. PubMed ID: 10631182

Yoon, B. S., et al. (2006). BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development 133(23): 4667-78. PubMed ID: 17065231

Yoshida, S., Morita, K., Mochii, M. and Ueno, N. (2001). Hypodermal expression of Caenorhabditis elegans TGF-beta type I receptor SMA-6 is essential for the growth and maintenance of body length. Dev. Biol. 240(1): 32-45. PubMed ID: 11784045

Yoshida, Y., et al. (2003). Tob proteins enhance inhibitory Smad-receptor interactions to repress BMP signaling. Mech. Dev. 120: 629-637. PubMed ID: 12782279

Yu, L., Hébert, M. C. and Zhang, Y. E. (2002). TGF-ß receptor-activated p38 MAP kinase mediates Smad-independent TGF-ß responses. EMBO J. 21: 3749-3759. PubMed ID: 12110587

Yuhki, M., et al. (2004). BMPR1A signaling is necessary for hair follicle cycling and hair shaft differentiation in mice. Development 131: 1825-1833. PubMed ID: 15084466

Yuva-Aydemir, Y., Bauke, A. C. and Klämbt, C. (2011). Spinster controls Dpp signaling during glial migration in the Drosophila eye. J. Neurosci. 31(19): 7005-15. PubMed ID: 21562262

Zaffran, S. and Frasch, M. (2000). Barbu: an E(spl) m4/malpha-related gene that antagonizes Notch signaling and is required for the establishment of ommatidial polarity. Development 127: 1115-1130. PubMed ID: 10662650

Zhang, X., Rui, M., Gan, G., Huang, C., Yi, J., Lv, H. and Xie, W. (2017). Neuroligin 4 regulates synaptic growth via the Bone morphogenetic protein (BMP) signaling pathway at the Drosophila neuromuscular junction. J Biol Chem [Epub ahead of print]. PubMed ID: 28912273

Zhang, Y., et al. (2009). Rock2 controls TGFbeta signaling and inhibits mesoderm induction in zebrafish embryos. J. Cell Sci. 122(Pt 13): 2197-207. PubMed ID: 19509062

Zhang, Z., et al. (2000). Targeted misexpression of constitutively active BMP receptor-IB causes bifurcation, duplication, and posterior tansformation of digit in mouse limb. Dev. Biol. 220: 154-167. PubMed ID: 10753507

Zhu, C. H. and Xie, T. (2003). Clonal expansion of ovarian germline stem cells during niche formation in Drosophila. Development 130: 2579-2588. PubMed ID: 12736203


thickveins: Biological Overview | Evolutionary Homologs | Regulation | Protein Interactions | Developmental Biology | Effects of Mutation

date revised: 22 December 2017
 

Home page: The Interactive Fly © 1997 Thomas B. Brody, Ph.D.

The Interactive Fly resides on the
Society for Developmental Biology's Web server.