REFERENCES (part 2/2)

Naik, U. P., Patel, P. M. and Parise, L. V. (1997). Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain. J. Biol. Chem. 272(8): 4651-4. PubMed ID: 9030514

Nakahara, H., et al. (1998). Activation of beta1 integrin signaling stimulates tyrosine phosphorylation of p190RhoGAP and membrane-protrusive activities at invadopodia. J. Biol. Chem. 273(1): 9-12. PubMed ID: 9417037

Newham, P., et al. (1997). Alpha4 integrin binding interfaces on VCAM-1 and MAdCAM-1. Integrin binding footprints identify accessory binding sites that play a role in integrin specificity. J. Biol. Chem. 272(31): 19429-19440. PubMed ID: 9235944

Ng, B. F., Selvaraj, G. K., Mateos, C. S., Grosheva, I., Alvarez-Garcia, I., Martin-Bermudo, M. D. and Palacios, I. M. (2016). Alpha-Spectrin and integrins act together to regulate actomyosin and columnarization, and to maintain a mono-layered follicular epithelium. Development 143(8):1388-99. PubMed ID: 26952981

Ng, D. H., Humphries, J. D., Byron, A., Millon-Fremillon, A. and Humphries, M. J. (2014). Microtubule-dependent modulation of adhesion complex composition. PLoS One 9(12): e115213. PubMed ID: 25526367

Ng, T., et al. (2001). Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motility. EMBO J. 20: 2723-2741. PubMed ID: 11387207

Niessen, C. M., et al. (1997). A minimal region on the integrin beta4 subunit that is critical to its localization in hemidesmosomes regulates the distribution of HD1/plectin in COS-7 cells. J. Cell Sci. 110:1705-1716. PubMed ID: 9264458

Nishimura, T. and Kaibuchi, K. (2007). Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3. Dev. Cell 13(1): 15-28. PubMed ID: 17609107

Oktay, M., et al. (1999). Integrin-mediated activation of focal adhesion kinase Is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle. J. Cell Biol. 145: 1461-1469. PubMed ID: 10385525

Pabla, R., et al. (1999). Integrin-dependent control of translation: engagement of integrin alphaIIbbeta3 regulates synthesis of proteins in activated human platelets. J. Cell Biol. 144(1): 175-84. PubMed ID: 9885253

Pankratz, M. J. and Hoch, M. (1995). Control of epithelial morphogenesis by cell signaling and integrin molecules in the Drosophila foregut. Development 121: 1885-1898. PubMed ID: 7601002

Patel, M., Margaron, Y., Fradet, N., Yang, Q., Wilkes, B., Bouvier, M., Hofmann, K. and Cote, J. F. (2010). An evolutionarily conserved autoinhibitory molecular switch in ELMO proteins regulates Rac signaling. Curr Biol 20: 2021-2027. PubMed ID: 21035343

Peng, X. et al. (2008). Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice. Proc. Natl. Acad. Sci. 105: 6638-6643. PubMed ID: 18448675

Persad, S., et al. (2000). Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis in PTEN null prostate cancer cells. Proc. Natl. Acad. Sci. 97: 3207-3212. PubMed ID: 10716737

Pietri, T., et al. (2004). Conditional ß1-integrin gene deletion in neural crest cells causes severe developmental alterations of the peripheral nervous system. Development 131: 3871-3883. PubMed ID: 15253938

Pines, M., Das, R., Ellis, S. J., Morin, A., Czerniecki, S., Yuan, L., Klose, M., Coombs, D. and Tanentzapf, G. (2012). Mechanical force regulates integrin turnover in Drosophila in vivo. Nat Cell Biol 14(9): 935-943. PubMed ID: 22885771

Poinat, P., et al. (2002). A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans. Curr. Biol. 12(8): 622-31. PubMed ID: 11967148

Polte, T.R. and Hanks, S.K. (1995). Interaction between focal adhesion kinase and Crk-associate tyrosine kinase substrate p130Cas. Proc Natl Acad Sci 92: 10678-82. PubMed ID: 7479864

Prieto, A. L., Edelman G. M. and Crossin, K. L. (1993). Multiple integrins mediate cell attachment to cytotactin/tenascin. Proc. Natl. Acad. Sci. 90 (21): 10154-10158. PubMed ID: 7694284

Prokop, A., et al. (1998). Absence of PS integrins or Laminin A affects extracellular adhesion, but not intracellular assembly, of hemiadherens and neuromuscular junctions in Drosophila embryos. Dev. Biol. 196(1): 58-76. PubMed ID: 9527881

Prout, M., Damania, Z., Soong, J., Fristrom, D. and Fristrom, J. W. (1997). Autosomal mutations affecting adhesion between wing surfaces in Drosophila melanogaster. Genetics: 146: 275-285. PubMed ID: 9136017

Rabinovitz, I. and Mercurio, A. M. (1997). The integrin alpha6beta4 functions in carcinoma cell migration on Laminin-1 by mediating the formation and stabilization of actin-containing motility structures. J. Cell Biol. 139(7): 1873-1884. PubMed ID: 9412479

Radeva, G., et al. (1997). Overexpression of the integrin-linked kinase promotes anchorage-independent cell cycle progression. J. Biol. Chem. 272 (21): 13937-13944. PubMed ID: 9153256

Raghavan, S., Vaezi, A. and Fuchs, E. (2003). A role for alphaß1 integrins in focal adhesion function and polarized cytoskeletal dynamics. Dev. Cell 5: 415-427. PubMed ID: 12967561

Rapisarda, V., Borghesan, M., Miguela, V., Encheva, V., Snijders, A. P., Lujambio, A. and O'Loghlen, A. (2017). Integrin β 3 regulates cellular senescence by activating the TGF-β pathway. Cell Rep 18(10): 2480-2493. PubMed ID: 28273461

Reed, B. H., Wilk, R., Schöck, F. and and Lipshitz, H. D. (2004), Integrin-dependent apposition of Drosophila extraembryonic membranes promotes morphogenesis and prevents anoikis. Curr. Biol. 14: 372-380. PubMed ID: 15028211

Relvas, J. B., et al. (2001). Expression of dominant-negative and chimeric subunits reveals an essential role for ß1 integrin during myelination. Curr. Bio. 11: 1039-1043. PubMed ID: 11470408

Ribeiro, I., Yuan, L., Tanentzapf, G., Dowling, J. J. and Kiger, A. (2011). Phosphoinositide regulation of integrin trafficking required for muscle attachment and maintenance. PLoS Genet. 7(2): e1001295. PubMed ID: 21347281

Richardson, A., et al. (1997). Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of Src or catalytically inactive FAK: a role for paxillin tyrosine phosphorylation. Mol. Cell. Biol. 17(12): 6906-6914. PubMed ID: 9372922

Romzek, N. C., et al. (1998). Use of a beta1 integrin-deficient human T cell to identify beta1 integrin cytoplasmic domain sequences critical for integrin function. Mol. Biol. Cell 9(10): 2715-27. PubMed ID: 9763439

Roote, C. E. and Zusman, S. (1995). Functions for PS integrins in tissue adhesion, migration, and shape changes during early embryonic development in Drosophila. Dev Biol 169: 322-336. PubMed ID: 7750648

Rosmarin, A. G., et al. (1998). Sp1 Cooperates with the ets transcription factor, GABP, to activate the CD18 (beta2 Leukocyte Integrin) promoter. J. Biol. Chem. 273(21): 13097-13103. PubMed ID: 9582348

Rupp, P. A., Czirók, A. and Little, C. D. (2004). alphavß3 integrin-dependent endothelial cell dynamics in vivo. Development 131: 2887-2897. PubMed ID: 15151986

Rushton, E., Rohrbough, J. and Broadie, K. (2009). Presynaptic secretion of mind-the-gap organizes the synaptic extracellular matrix-integrin interface and postsynaptic environments. Dev Dyn 238: 554-571. PubMed ID:19235718

Rusnati, M., et al. (1997). alphavbeta3 integrin mediates the cell-adhesive capacity and biological activity of basic fibroblast growth factor (FGF-2) in cultured endothelial cells. Mol. Biol. Cell 8(12): 2449-2461. PubMed ID: 9398667

Sakai, T., et al. (1998). Modulation of beta1A integrin functions by tyrosine residues in the beta1 cytoplasmic domain. J. Cell Biol. 141(2): 527-538. PubMed ID: 9548729

Sandstrom, D. J., et al. (1997). Broad-Complex transcription factors regulate muscle attachment in Drosophila. Dev. Biol. 181: 168-185. PubMed ID: 9013928

Sanjay, A., et al. (2001). Cbl associates with Pyk2 and Src to regulate Src kinase activity, alphavß3 integrin-mediated signaling, cell adhesion, and osteoclast motility. J. Cell Bio. 152: 181-196. PubMed ID: 11149930

Santoro, M. M., Gaudino, G. and Marchisio, P. C. (2003). The MSP receptor regulates alpha6beta4 and alpha3beta1 integrins via 14-3-3 proteins in keratinocyte migration. Dev. Cell 5: 257-271. PubMed ID: 12919677

Sastry, S. K., et al. (1999). Quantitative changes in integrin and focal adhesion signaling regulate myoblast cell cycle withdrawal. J. Cell Biol. 144(6): 1295-1309 . PubMed ID: 10087271

Sattler, M., et al. (1997). Differential signaling after beta1 integrin ligation is mediated through binding of CRKL to p120(CBL) and p110(HEF1). J. Biol. Chem. 272 (22): 14320-14326. PubMed ID: 9162067

Sasaki, T., et al. (1998). Deficiency of beta 1 integrins in teratoma interferes with basement membrane assembly and laminin-1 expression. Exp. Cell Res. 238(1): 70-81. PubMed ID: 9457058

Schlaepfer, D. D. and Hunter, T. (1997). Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src. J. Biol. Chem. 272(20): 13189-13195. PubMed ID: 9148935

Schmid, R. S., et al. (2005). alpha3beta1 integrin modulates neuronal migration and placement during early stages of cerebral cortical development. Development. 131(24): 6023-31. PubMed ID: 15537685

Schneller. M., Vuori, K. and Ruoslahti, E. (1997). alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF. EMBO J. 16(18): 5600-5607. PubMed ID: 9312019

Schwander, M., et al. (2003). ß1 integrins regulate myoblast fusion and sarcomere assembly. Developmental Cell 4: 673-685. PubMed ID: 12737803

Senger, D. R., et al. (1997). Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins. Proc. Natl. Acad. Sci. 94(25): 13612-13617. PubMed ID: 9391074

Shimaoka, M., et al. (2003). Structures of the alphaL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation. Cell 112: 99-111. PubMed ID: 12526797

Shinohara, T., Avarbock, M. R. and, Brinster, R. L. (1999). beta1- and alpha6-integrin are surface markers on mouse spermatogonial stem cells. Proc. Natl. Acad. Sci. 96(10): 5504-9. PubMed ID: 10318913

Shock, D. D., et al (1999). Calcium-dependent properties of CIB binding to the integrin alphaIIb cytoplasmic domain and translocation to the platelet cytoskeleton. Biochem J. 342 Pt3: 729-35. PubMed ID: 10477286

Soba, P., Han, C., Zheng, Y., Perea, D., Miguel-Aliaga, I., Jan, L. Y. and Jan, Y. N. (2015). The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion. Elife 4. PubMed ID: 25764303

Stark, K. A., et al. (1997). A novel alpha integrin subunit associates with betaPS and functions in tissue morphogenesis and movement during Drosophila development. Development 124(22): 4583-4594

Stenzel, D., et al. (2011). Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis. Development 138(20): 4451-63. PubMed ID: 21880786

Stevens, A. and Jacobs, J. R. (2002). Integrins regulate responsiveness to Slit repellent signals. J. Neurosci. 22(11): 4448-4455. PubMed ID: 12040052

Subramanian, A., Wayburn, B., Bunch, T. and Volk, T. (2007). Thrombospondin-mediated adhesion is essential for the formation of the myotendinous junction in Drosophila. Development 134(7): 1269-78. PubMed ID: 17314133

Tahiliani, P. D., et al. (1997). The role of conserved amino acid motifs within the integrin beta3 cytoplasmic domain in triggering focal adhesion kinase phosphorylation. J. Biol. Chem. 272(12): 7892-7898. PubMed ID: 9065456

Takagi, J., et al. (1997). Changing ligand specificities of alphavbeta1 and alphavbeta3 integrins by swapping a short diverse sequence of the beta subunit. J. Biol. Chem. 272(32): 19794-19800. PubMed ID: 9242639

Takagi, J., et al. (2002). Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling. Cell 110: 599-611. PubMed ID: 12230977

Tanentzapf, G., et al. (2006a). Multiple factors contribute to integrin-talin interactions in vivo. J. Cell Sci. 119: 1632-1644. PubMed ID: 16569666

Tanentzapf, G. and Brown, N. H. (2006b). An interaction between integrin and the talin FERM domain mediates integrin activation but not linkage to the cytoskeleton. Nature Cell Biol. 8: 601-606. PubMed ID: 16648844

Tepass, U. and Hartenstein, J. (1994). Epithelium formation in the Drosophila midgut depends on the interaction of endoderm and mesoderm. Development 120: 579-590. PubMed ID: 8162857

Tiger, C.-F., et al. (2001). alpha1ß11 integrin is a receptor for interstitial collagens involved in cell migration and collagen reorganization on mesenchymal nonmuscle cells. Dev. Bio. 237: 116-129. PubMed ID: 11518510

Tremuth, L., Kreis, S., Melchior, C., Hoebeke, J., Ronde, P., Plancon, S., Takeda, K. and Kieffer, N. (2004). A fluorescence cell biology approach to map the second integrin-binding site of talin to a 130-amino acid sequence within the rod domain. J. Biol. Chem. 279: 22258-22266. PubMed ID: 15031296

Trusolino, L., et al. (1998). Growth factor-dependent activation of alphavbeta3 integrin in normal epithelial cells: implications for tumor invasion. J. Cell Biol. 142(4): 1145-56. PubMed ID: 9722624

Ulmer, T. S., Calderwood, D. A., Ginsberg, M. H. and Campbell, I. D. (2003). Domain-specific interactions of talin with the membrane-proximal region of the integrin beta3 subunit. Biochemistry 42: 8307-8312. PubMed ID: 12846579

Urbano, J. M., Dominguez-Giménez, P., Estrada, B. and Martin-Bermudo, M. D. (2011). PS integrins and laminins: key regulators of cell migration during Drosophila embryogenesis. PLoS One. 6(9): e23893. PubMed ID: 21949686

Vallar, L., et al. (1999). Divalent cations differentially regulate integrin alphaIIb cytoplasmic tail binding to beta3 and to calcium- and integrin-binding protein. J. Biol. Chem. 274(24): 17257-66. PubMed ID: 10358085

Vanderploeg, J. and Jacobs, R. (2015). Talin is required to position and expand the luminal domain of the Drosophila heart tube. Dev Biol [Epub ahead of print]. PubMed ID: 25958089

Vignoud, L., et al. (1997). NPXY motifs control the recruitment of the alpha5beta1 integrin in focal adhesions independently of the association of talin with the beta1 chain. J. Cell Sci. 110:1421-1430. PubMed ID: 9217328

Vinogradova, O., et al. (2002). A structural mechanism of integrin alphaIIß3 'inside-out' activation as regulated by its cytoplasmic face. Cell 110: 587-597. PubMed ID: 12230976

Vivinus-Nebot, M., et al. (1999). Laminin 5 in the human thymus: Control of T cell proliferation via alpha6beta4 integrins. J. Cell Biol. 144(3): 563-574. PubMed ID: 9971749

Volk, T., Fessler, L. I. and Fessler, J. H. (1990). A role for integrin in the formation of sarcomeric cytoarchitecture. Cell 63: 525-36. PubMed ID: 2225065

Wahlström, G., Norokorpi, H. L. and Heino, T. I. (2006). Drosophila alpha-actinin in ovarian follicle cells is regulated by EGFR and Dpp signalling and required for cytoskeletal remodelling. Mech. Dev. 123(11): 801-18. PubMed ID: 17008069

Walser, M., Umbricht, C.A., Fröhli, E., Nanni, P. and Hajnal, A. (2017). β-Integrin de-phosphorylation by the Density-Enhanced Phosphatase DEP-1 attenuates EGFR signaling in C. elegans. PLoS Genet [Epub ahead of print]. PubMed ID: 28135265

Wang, J., Mayernik, L. and Armant, D. R. (2002). Integrin signaling regulates blastocyst adhesion to fibronectin at implantation: intracellular calcium transients and vesicle trafficking in primary trophoblast cells. Dev. Biol. 245: 270-279. PubMed ID: 11977980

Wang, Q., Han, T. H., Nguyen, P., Jarnik, M. and Serpe, M. (2018). Tenectin recruits integrin to stabilize bouton architecture and regulate vesicle release at the Drosophila neuromuscular junction. Elife 7. PubMed ID: 29901439

Wang, X. Q. and Frazier, W. A. (1998). The thrombospondin receptor CD47 (IAP) modulates and associates with alpha2 beta1 integrin in vascular smooth muscle cells. Mol. Biol. Cell 9(4): 865-74. PubMed ID: 9529384

Wegener, K. L., et al. (2007). Structural basis of integrin activation by Talin. Cell 128(1): 171-82. PubMed ID: 17218263

Wells, A. R., Zou, R. S., Tulu, U. S., Sokolow, A. C., Crawford, J. M., Edwards, G. S. and Kiehart, D. P. (2014). Complete canthi removal reveals that forces from the amnioserosa alone are sufficient to drive dorsal closure in Drosophila. Mol Biol Cell 25: 3552-3568. PubMed ID: 25253724

Wen, L. P., et al. (1997). Cleavage of focal adhesion kinase by caspases during apoptosis. J. Biol. Chem. 272(41): 26056-61. PubMed ID: 9325343

Whitlock, B. B., et al. (2000). Differential roles for alphaMß2 integrin clustering or activation in the control of apoptosis via regulation of Akt and ERK survival mechanisms. J. Cell Bio. 151: 1305-1320. PubMed ID: 11121444

Wolfsberg, T. G., et al. (1995). ADAM, a novel family of membrane proteins containing A Disintegrin And Metalloprotease Domain: Multiple functions in cell-cell and cell-matrix interactions. J. Cell Biol. 131: 275-278. PubMed ID: 7593158

Wu, X., et al. (1998). Modulation of calcium current in arteriolar smooth muscle by alphavbeta3 and alpha5beta1 integrin ligands. J. Cell Biol. 143(1): 241-52. PubMed ID: 9763435

Xavier, M. J. and Williams, M. J. (2011). The Rho-family GTPase Rac1 regulates integrin localization in Drosophila immunosurveillance cells. PLoS One 6(5): e19504. PubMed ID: 21603603

Xie, X. and Auld, V. J. (2011). Integrins are necessary for the development and maintenance of the glial layers in the Drosophila peripheral nerve. Development 138(17): 3813-22. PubMed ID: 21828098

Xie, X., Gilbert, M., Petley-Ragan, L., Auld, V. J. (2014), Loss of focal adhesions in glia disrupts both glial and photoreceptor axon migration in the Drosophila visual system. Development 141: 3072-3083. PubMed ID: 25053436

Yamakita, Y., et al. (1999). Dissociation of FAK/p130(CAS)/c-Src complex during mitosis: role of mitosis-specific serine phosphorylation of FAK. J. Cell Biol. 144(2): 315-24. PubMed ID: 9922457

Yebra, M., et al. (2003). Recognition of the neural chemoattractant Netrin-1 by integrins α6β4 and α3β1 regulates epithelial cell adhesion and migration. Dev. Cell 5: 695-707. PubMed ID: 14602071

Yokosaki, Y., et al. (1994). The integrin alpha 9 beta 1 mediates cell attachment to a non-RGD site in the third fibronectin type III repeat of tenascin. J. Biol. Chem. 269 (43): 26691-26696. PubMed ID: 7523411

Yu, K., et al. (1996). The Drosophila decapentaplegic and short gastrulation genes function antagonistically during adult wing vein development. Development 122: 4033-4044. PubMed ID: 9012523

Yuan, L., Fairchild, M. J., Perkins, A. D. and Tanentzapf, G. (2010). Analysis of integrin turnover in fly myotendinous junctions. J. Cell Sci. 123(Pt 6): 939-46. PubMed ID: 20179102

Zhao, J. H., Reiske, H. and Guan, J. L. (1998). Regulation of the cell cycle by focal adhesion kinase. J. Cell Biol. 143(7): 1997-2008. PubMed ID: 9864370

Zhu, A. J., Haase, I. and Watt, F. M. (1999). Signaling via beta1 integrins and mitogen-activated protein kinase determines human epidermal stem cell fate in vitro. Proc. Natl. Acad. Sci. 96: 6728-6733. PubMed ID: 10359780

Zhu, J., et al. (2002). ß8 integrins are required for vascular morphogenesis in mouse embryos. Development 129: 2891-2903. PubMed ID: 12050137

Zito, K., Parnas, D., Fetter, R. D., Isacoff, E. Y. and Goodman, C. S. (1999). Watching a synapse grow: noninvasive confocal imaging of synaptic growth in Drosophila. Neuron 22: 719-729. PubMed ID: 10230792

Zovein, A. C., et al. (2010). Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism. Dev. Cell 18(1): 39-51. PubMed ID: 20152176

Zuccotti, M., et al. (1998). Timing of gene expression and oolemma localization of mouse alpha6 and beta1 integrin subunits during oogenesis. Dev. Biol. 200(1): 27-34. PubMed ID: 9698453

Zusman, S., et al. (1990). Requirements for integrins during Drosophila development. Development 108: 391-402. PubMed ID: 2340808

Zusman, S., et al. (1993). Analyses of PS integrin functions during Drosophila development. Development 118: 737-750. PubMed ID: 8076515

return to References part 1/2

myospheroid: Biological Overview | Evolutionary Homologs | Regulation | Developmental Biology | Effects of Mutation

date revised: 10 August 2018 

Home page: The Interactive Fly © 1997 Thomas B. Brody, Ph.D.

The Interactive Fly resides on the
Society for Developmental Biology's Web server.