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Stow, E. C., Simmons, J. R., An, R., Schoborg, T. A., Davenport, N. M. and Labrador, M. (2022). A Drosophila insulator interacting protein suppresses enhancer-blocking function and modulates replication timing. Gene 819: 146208. PubMed ID: 35092858 Hsu, S. J., Stow, E. C., Simmons, J. R., Wallace, H. A., Lopez, A. M., Stroud, S. and Labrador, M. (2020). Mutations in the insulator protein Suppressor of Hairy wing induce genome instability. Chromosoma 129(3-4): 255-274. PubMed ID: 33140220 Asadzadeh, J., Neligan, N., Kramer, S.G. and Labrador, J.P. (2016). Tinman regulates NetrinB in the cardioblasts of the Drosophila dorsal vessel. PLoS One 11: e0148526. PubMed ID: 26840059 Asadzadeh, J., Neligan, N., Canabal-Alvear, J. J., Daly, A. C., Kramer, S. G. and Labrador, J. P. (2015). The Unc-5 Receptor Is Directly Regulated by Tinman in the Developing Drosophila Dorsal Vessel. PLoS One 10: e0137688. PubMed ID: 26356221 Hsu, S.J., Plata, M.P., Ernest, B., Asgarifar, S. and Labrador, M. (2015). The insulator protein Suppressor of Hairy wing is required for proper ring canal development during oogenesis in Drosophila. Dev Biol [Epub ahead of print]. PubMed ID: 25882370 Schoborg, T. and Labrador, M. (2014). Expanding the roles of chromatin insulators in nuclear architecture, chromatin organization and genome function. Cell Mol Life Sci 71: 4089-4113. PubMed ID: 25012699 Zarin, A. A., Asadzadeh, J., Hokamp, K., McCartney, D., Yang, L., Bashaw, G. J. and Labrador, J. P. (2014). A Transcription Factor Network Coordinates Attraction, Repulsion, and Adhesion Combinatorially to Control Motor Axon Pathway Selection. Neuron. PubMed ID: 24560702 Schoborg, T., Kuruganti, S., Rickels, R. and Labrador, M. (2013). The Drosophila gypsy Insulator Supports Transvection in the Presence of the vestigial Enhancer. PLoS One 8: e81331. PubMed ID: 24236213 Schoborg, T., Rickels, R., Barrios, J. and Labrador, M. (2013). Chromatin insulator bodies are nuclear structures that form in response to osmotic stress and cell death. J Cell Biol 202: 261-276. PubMed ID: 23878275 Schauer, T., Schwalie, P. C., Handley, A., Margulies, C. E., Flicek, P. and Ladurner, A. G. (2013). CAST-ChIP Maps Cell-Type-Specific Chromatin States in the Drosophila Central Nervous System. Cell Rep. PubMed ID: 24095734 Czarna, A., Berndt, A., Singh, H. R., Grudziecki, A., Ladurner, A. G., Timinszky, G., Kramer, A. and Wolf, E. (2013). Structures of Drosophila cryptochrome and mouse cryptochrome1 provide insight into circadian function. Cell 153: 1394-1405. PubMed ID: 23746849 Murawska, M., Hassler, M., Renkawitz-Pohl, R., Ladurner, A. and Brehm, A. (2011). Stress-induced PARP activation mediates recruitment of Drosophila Mi-2 to promote heat shock gene expression. PLoS Genet 7: e1002206. PubMed ID: 21829383 Vedanayagam, J., Lin, C. J. and Lai, E. C. (2021). Rapid evolutionary dynamics of an expanding family of meiotic drive factors and their hpRNA suppressors. Nat Ecol Evol 5(12): 1613-1623. PubMed ID: 34862477 Joseph, B., Scala, C., Kondo, S. and Lai, E. C. (2022). Molecular and genetic dissection of recursive splicing. Life Sci Alliance 5(1). PubMed ID: 34759052 Garaulet, D. L., Moro, A. and Lai, E. C. (2021). A double-negative gene regulatory circuit underlies the virgin behavioral state. Cell Rep 36(1): 109335. PubMed ID: 34233178 Lee, S., Wei, L., Zhang, B., Goering, R., Majumdar, S., Wen, J., Taliaferro, J. M. and Lai, E. C. (2021). ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing. PLoS Genet 17(4): e1009439. PubMed ID: 33826609 Kan, L., Ott, S., Joseph, B., Park, E. S., Dai, W., Kleiner, R. E., Claridge-Chang, A. and Lai, E. C. (2021). A neural m(6)A/Ythdf pathway is required for learning and memory in Drosophila. Nat Commun 12(1): 1458. PubMed ID: 33674589 Bejarano, F., Chang, C. H., Sun, K., Hagen, J. W., Deng, W. M. and Lai, E. C. (2021). A comprehensive in vivo screen for anti-apoptotic miRNAs indicates broad capacities for oncogenic synergy. Dev Biol 475: 10-20. PubMed ID: 33662357 Wei, L., Lee, S., Majumdar, S., Zhang, B., Sanfilippo, P., Joseph, B., Miura, P., Soller, M. and Lai, E. C. (2020). Overlapping Activities of ELAV/Hu Family RNA Binding Proteins Specify the Extended Neuronal 3' UTR Landscape in Drosophila. Mol Cell 80(1): 140-155.e146. PubMed ID: 33007254 Mazaud, D., Kottler, B., Goncalves-Pimentel, C., Proelss, S., Tuchler, N., Deneubourg, C., Yuasa, Y., Diebold, C., Jungbluth, H., Lai, E. C., Hirth, F., Giangrande, A. and Fanto, M. (2019). Transcriptional regulation of the Glutamate/GABA/Glutamine cycle in adult glia controls motor activity and seizures in Drosophila. J Neurosci. PubMed ID: 31064860 Bag, I., Dale, R. K., Palmer, C. and Lei, E. P. (2019). The zinc-finger protein CLAMP promotes gypsy chromatin insulator function in Drosophila. J Cell Sci. PubMed ID: 30718365 Lin, C. J., Hu, F., Dubruille, R., Vedanayagam, J., Wen, J., Smibert, P., Loppin, B. and Lai, E. C. (2018). The hpRNA/RNAi pathway is essential to resolve intragenomic conflict in the Drosophila male germline. Dev Cell 46(3): 316-326.e315. PubMed ID: 30086302 Joseph, B., Kondo, S. and Lai, E. C. (2018). Short cryptic exons mediate recursive splicing in Drosophila. Nat Struct Mol Biol. PubMed ID: 29632374 Zhang, Y. and Lai, Z. C. (2013). Mob as tumor suppressor is regulated by bantam microRNA through a feedback loop for tissue growth control. Biochem Biophys Res Commun 439: 438-442. PubMed ID: 24016667 Zhang, Y. and Lai, Z. C. (2013). Mob as tumor suppressor is regulated by bantam microRNA through a feedback loop for tissue growth control. Biochem Biophys Res Commun. PubMed ID: 24016667 Deng, Y., Matsui, Y., Zhang, Y., Lai, Z. C. (2013) Hippo activation through homodimerization and membrane association for growth inhibition and organ size control. Dev Biol 375: 152-159. PubMed ID: 23298890 Ye, X., Deng, Y., and Z.-C. Lai. 2012. Akt is negatively regulated by Hippo signaling for growth inhibition in Drosophila. Dev. Biol. 369: 115-123. PubMed ID: 22732571 Ho, L.-L., X. Wei, T. Shimizu, and Z.-C. Lai. 2010. Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in Drosophila. Dev. Biol 337: 274-283. PubMed Citation: 19913529 Ray, M. and Lakhotia, S. C. (2019). Activated Ras/JNK driven Dilp8 in imaginal discs adversely affects organismal homeostasis during early pupal stage in Drosophila, a new checkpoint for development. Dev Dyn. PubMed ID: 31415125 Singh, A.K. and Lakhotia, S.C. (2015). The hnRNP A1 homolog Hrb87F/Hrp36 is important for telomere maintenance in Drosophila melanogaster. Chromosoma [Epub ahead of print]. PubMed ID: 26373285 Singh, A. K. and Lakhotia, S. C. (2015). Dynamics of hnRNPs and omega speckles in normal and heat shocked live cell nuclei of Drosophila melanogaster. Chromosoma. PubMed ID: 25663367 Singh, A. K. and Lakhotia, S. C. (2012). The hnRNP A1 homolog Hrp36 is essential for normal development, female fecundity, omega speckle formation and stress tolerance in Drosophila melanogaster. J Biosci 37: 659-678. PubMed ID: 22922191 Lakhotia, S. C., Mallik, M., Singh, A. K. and Ray, M. (2012). The large noncoding hsromega-n transcripts are essential for thermotolerance and remobilization of hnRNPs, HP1 and RNA polymerase II during recovery from heat shock in Drosophila. Chromosoma 121: 49-70. PubMed ID: 21913129 Parkash, R., Singh, D. and Lambhod, C. (2013). Divergent strategies for adaptations to stress resistance in two tropical Drosophila species: effects of developmental acclimation for D. bipectinata and the invasive species - D. malerkotliana. J Exp Biol. PubMed ID: 24265421 Parkash, R., Aggarwal, D. D., Lambhod, C. and Singh, D. (2013). Divergence of water balance mechanisms and acclimation potential in body color morphs of Drosophila ananassae. J Exp Zool A Ecol Genet Physiol. PubMed ID: 24167067 Lander, A. D., Nie, Q., Sanchez-Tapia, C., Simonyan, A. and Wan, F. Y. M. (2020). Regulatory feedback on receptor and non-receptor synthesis for robust signaling. Dev Dyn 249(3): 383-409. PubMed ID: 32034817 Newkirk, D. A., Chen, Y. Y., Chien, R., Zeng, W., Biesinger, J., Flowers, E., Kawauchi, S., Santos, R., Calof, A. L., Lander, A. D., Xie, X. and Yokomori, K. (2017). The effect of Nipped-B-like (Nipbl) haploinsufficiency on genome-wide cohesin binding and target gene expression: modeling Cornelia de Lange syndrome. Clin Epigenetics 9: 89. PubMed ID: 28855971 Wortman, J. C., Nahmad, M., Zhang, P. C., Lander, A. D. and Yu, C. C. (2017). Expanding signaling-molecule wavefront model of cell polarization in the Drosophila wing primordium. PLoS Comput Biol 13(7): e1005610. PubMed ID: 28671940 Giachello, C. N. G., Fan, Y. N., Landgraf, M. and Baines, R. A. (2021). Nitric oxide mediates activity-dependent change to synaptic excitation during a critical period in Drosophila. Sci Rep 11(1): 20286. PubMed ID: 34645891 Dhawan, S., Myers, P., Bailey, D. M. D., Ostrovsky, A. D., Evers, J. F. and Landgraf, M. (2021). Reactive Oxygen Species Mediate Activity-Regulated Dendritic Plasticity Through NADPH Oxidase and Aquaporin Regulation. Front Cell Neurosci 15: 641802. PubMed ID: 34290589 Valdes-Aleman, J., Fetter, R. D., Sales, E. C., Heckman, E. L., Venkatasubramanian, L., Doe, C. Q., Landgraf, M., Cardona, A. and Zlatic, M. (2020). Comparative Connectomics Reveals How Partner Identity, Location, and Activity Specify Synaptic Connectivity in Drosophila. Neuron. PubMed ID: 33120017 Oswald, M. C. W., Brooks, P. S., Zwart, M. F., Mukherjee, A., West, R. J. H., Giachello, C. N. G., Morarach, K., Baines, R. A., Sweeney, S. T. and Landgraf, M. (2018). Reactive oxygen species regulate activity-dependent neuronal plasticity in Drosophila. Elife 7. PubMed ID: 30540251 Zwart, M.F., Pulver, S,R., Truman, J.W., Fushiki, A., Cardona, A. and Landgraf, M. (2016). Selective inhibition mediates the sequential recruitment of motor pools. Neuron [Epub ahead of print]. PubMed ID: 27427461 Peco, E., Davla, S., Camp, D., Stacey, S., Landgraf, M. and van Meyel, D. (2016). Drosophila astrocytes cover specific territories of CNS neuropil and are instructed to differentiate by Prospero, a key effector of Notch. Development [Epub ahead of print]. PubMed ID: 26893340 Picao-Osorio, J., Johnston, J., Landgraf, M., Berni, J. and Alonso, C.R. (2015).MicroRNA-encoded behavior in Drosophila. Science [Epub ahead of print]. PubMed ID: 26494171 Diao, F., Ironfield, H., Luan, H., Diao, F., Shropshire, W. C., Ewer, J., Marr, E., Potter, C. J., Landgraf, M. and White, B. H. (2015). Plug-and-play genetic access to Drosophila cell types using exchangeable exon cassettes. Cell Rep 10: 1410-1421. PubMed ID: 25732830 Couton, L., Mauss, A. S., Yunusov, T., Diegelmann, S., Evers, J. F. and Landgraf, M. (2015). Development of connectivity in a motoneuronal network in Drosophila larvae. Curr Biol 25: 568-576. PubMed ID: 25702582 Zwart, M. F., Randlett, O., Evers, J. F. and Landgraf, M. (2013). Dendritic growth gated by a steroid hormone receptor underlies increases in activity in the developing Drosophila locomotor system. Proc Natl Acad Sci U S A. PubMed ID: 24043825 Schubert, T., Langst, G. (2013) Changes in higher order structures of chromatin by RNP complexes. RNA Biol 10. PubMed ID: 23353578 Schubert, T., Pusch, M. C., Diermeier, S., Benes, V., Kremmer, E., Imhof, A. and Langst, G. (2012). Df31 protein and snoRNAs maintain accessible higher-order structures of chromatin. Mol Cell 48: 434-444. PubMed ID: 23022379 Biehler, C., Wang, L. T., Sevigny, M., Jette, A., Gamblin, C. L., Catterall, R., Houssin, E., McCaffrey, L. and Laprise, P. (2020). Girdin is a component of the lateral polarity protein network restricting cell dissemination. PLoS Genet 16(3): e1008674. PubMed ID: 32196494 Houssin, E., Tepass, U. and Laprise, P. (2015). Girdin-mediated interactions between cadherin and the actin cytoskeleton are required for epithelial morphogenesis in Drosophila. Development 142: 1777-1784. PubMed ID: 25968313 Gareau, C., Houssin, E., Martel, D., Coudert, L., Mellaoui, S., Huot, M. E., Laprise, P. and Mazroui, R. (2013). Characterization of fragile X mental retardation protein recruitment and dynamics in Drosophila stress granules. PLoS One 8: e55342. PubMed ID: 23408971 Chartier, F. J., Hardy, E. J. and Laprise, P. (2012). Crumbs limits oxidase-dependent signaling to maintain epithelial integrity and prevent photoreceptor cell death. J Cell Biol 198: 991-998. PubMed ID: 22965909 Chartier, F. J., Hardy, E. J. and Laprise, P. (2011). Crumbs controls epithelial integrity by inhibiting Rac1 and PI3K. J Cell Sci 124: 3393-3398. PubMed ID: 21984807 Cox, R. L., Hofley, C. M., Tatapudy, P., Patel, R. K., Dayani, Y., Betcher, M. and LaRocque, J. R. (2019). Functional conservation of RecQ helicase BLM between humans and Drosophila melanogaster. Sci Rep 9(1): 17527. PubMed ID: 31772289 Fernandez, J., Bloomer, H., Kellam, N. and LaRocque, J. R. (2019). Chromosome preference during homologous recombination repair of DNA double-strand breaks in Drosophila melanogaster. G3 (Bethesda). PubMed ID: 31519746 Ertl, H. A., Russo, D. P., Srivastava, N., Brooks, J. T., Dao, T. N. and LaRocque, J. R. (2017). The Role of Blm Helicase in homologous recombination, gene conversion tract length, and recombination between diverged sequences in Drosophila. Genetics [Epub ahead of print]. PubMed ID: 28912341 Delabaere, L., Ertl, H. A., Massey, D. J., Hofley, C. M., Sohail, F., Bienenstock, E. J., Sebastian, H., Chiolo, I. and LaRocque, J. R. (2016). Aging impairs double-strand break repair by homologous recombination in Drosophila germ cells. Aging Cell. PubMed ID: 28000382 Do, A. T. and LaRocque, J. R. (2015). The role of Drosophila mismatch repair in suppressing recombination between diverged sequences. Sci Rep 5: 17601. PubMed ID: 26616528 Do, A. T., Brooks, J. T., Le Neveu, M. K. and LaRocque, J. R. (2014). Double-strand break repair assays determine pathway choice and structure of gene conversion events in Drosophila melanogaster. G3 (Bethesda) 4(3): 425-432. PubMed ID: 24368780 Chang, C. H., Gregory, L. E., Gordon, K. E., Meiklejohn, C. D. and Larracuente, A. M. (2022). Unique structure and positive selection promote the rapid divergence of Drosophila Y chromosomes. Elife 11. PubMed ID: 34989337 Wei, X., Eickbush, D. G., Speece, I. and Larracuente, A. M. (2021). Heterochromatin-dependent transcription of satellite DNAs in the Drosophila melanogaster female germline. Elife 10. PubMed ID: 34259629 Chakraborty, M., Chang, C. H., Khost, D. E., Vedanayagam, J., Adrion, J. R., Liao, Y., Montooth, K. L., Meiklejohn, C. D., Larracuente, A. M. and Emerson, J. J. (2021). Evolution of genome structure in the Drosophila simulans species complex. Genome Res 31(3): 380-396. PubMed ID: 33563718 Duan, J., Rieder, L., Colonnetta, M. M., Huang, A., McKenney, M., Watters, S., Deshpande, G., Jordan, W., Fawzi, N. and Larschan, E. (2021). CLAMP and Zelda function together to promote Drosophila zygotic genome activation. Elife 10. PubMed ID: 34342574 Rieder, L. E., Jordan, W. T., 3rd and Larschan, E. N. (2019). Targeting of the dosage-compensated male X-chromosome during early Drosophila development. Cell Rep 29(13): 4268-4275.e4262. PubMed ID: 31875538 Kaye, E. G., Booker, M., Kurland, J. V., Conicella, A. E., Fawzi, N. L., Bulyk, M. L., Tolstorukov, M. Y. and Larschan, E. (2018). Differential occupancy of two GA-binding proteins promotes targeting of the Drosophila dosage compensation complex to the male X chromosome. Cell Rep 22(12): 3227-3239. PubMed ID: 29562179 Urban, J. A., Urban, J. M., Kuzu, G. and Larschan, E. N. (2017). The Drosophila CLAMP protein associates with diverse proteins on chromatin. PLoS One 12(12): e0189772. PubMed ID: 29281702 Urban, J., Kuzu, G., Bowman, S., Scruggs, B., Henriques, T., Kingston, R., Adelman, K., Tolstorukov, M. and Larschan, E. (2017). Enhanced chromatin accessibility of the dosage compensated Drosophila male X-chromosome requires the CLAMP zinc finger protein. PLoS One 12(10): e0186855. PubMed ID: 29077765 Kaye, E. G., Kurbidaeva, A., Wolle, D., Aoki, T., Schedl, P. and Larschan, E. (2017). Drosophila dosage compensation loci associate with a boundary forming insulator complex. Mol Cell Biol. [Epub ahead of print] PubMed ID: 28784719 Urban, J. A., Doherty, C. A., Jordan, W. T., 3rd, Bliss, J. E., Feng, J., Soruco, M. 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Odd-skipped labels a group of distinct neurons associated with the mushroom body and optic lobe in the adult Drosophila brain. J Comp Neurol. PubMed ID: 23749685 Larsen, C., Shy, D., Spindler, S. R., Fung, S., Pereanu, W., Younossi-Hartenstein, A. and Hartenstein, V. (2009). Patterns of growth, axonal extension and axonal arborization of neuronal lineages in the developing Drosophila brain. Dev Biol 335: 289-304. PubMed ID: 19538956 Ekhteraei-Tousi, S., Lewerentz, J. and Larsson, J. (2020). Painting of fourth and the X-linked 1.688 satellite in D. melanogaster is involved in chromosome-wide gene regulation. Cells 9(2). PubMed ID: 32019091 Kim, M., Faucillion, M. L. and Larsson, J. (2018). RNA-on-X 1 and 2 in Drosophila melanogaster fulfill separate functions in dosage compensation. PLoS Genet 14(12): e1007842. PubMed ID: 30532158 Kim, M., Ekhteraei-Tousi, S., Lewerentz, J. and Larsson, J. (2018). The X-linked 1.688 satellite in Drosophila melanogaster promotes specific targeting by Painting of fourth. Genetics 208(2): 623-632. PubMed ID: 29242291 Figueiredo, M. L., Kim, M., Philip, P., Allgardsson, A., Stenberg, P. and Larsson, J. (2014). Non-coding roX RNAs Prevent the Binding of the MSL-complex to Heterochromatic Regions. PLoS Genet 10: e1004865. PubMed ID: 25501352 Lundberg, L. E., Kim, M., Johansson, A. M., Faucillion, M. L., Josupeit, R. and Larsson, J. (2013). Targeting of Painting of Fourth to roX1 and roX2 Proximal Sites Suggests Evolutionary Links Between Dosage Compensation and the Regulation of the 4th Chromosome in Drosophila melanogaster. G3 (Bethesda). PubMed ID: 23733888 Lundberg, L. E., Stenberg, P., Larsson, J. (2013) HP1a, Su(var)3-9, SETDB1 and POF stimulate or repress gene expression depending on genomic position, gene length and expression pattern in Drosophila melanogaster. Nucleic Acids Res. PubMed ID: 23476027 Crona, F., Dahlberg, O., Lundberg, L. 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S., Vali, H., Lecuyer, E. and Lasko, P. (2019). A ribosomal protein S5 isoform is essential for oogenesis and interacts with distinct RNAs in Drosophila melanogaster. Sci Rep 9(1): 13779. PubMed ID: 31551467 Berlandi, J., Chaouch, A., De Jay, N., Tegeder, I., Thiel, K., Shirinian, M., Kleinman, C. L., Jeibmann, A., Lasko, P., Jabado, N. and Hasselblatt, M. (2019). Identification of genes functionally involved in the detrimental effects of mutant histone H3.3-K27M in Drosophila melanogaster. Neuro Oncol. PubMed ID: 30715493 Kowanda, M., Bergalet, J., Wieczorek, M., Brouhard, G., Lecuyer, E. and Lasko, P. (2016). Loss of function of the Drosophila Ninein-related centrosomal protein Bsg25D causes mitotic defects and impairs embryonic development. Biol Open [Epub ahead of print]. PubMed ID: 27422905 Valzania, L., Ono, H., Ignesti, M., Cavaliere, V., Bernardi, F., Gamberi, C., Lasko, P. and Gargiulo, G. (2015). Drosophila 4EHP is essential for the larval-pupal transition and required in the prothoracic gland for ecdysone biosynthesis. Dev Biol. PubMed ID: 26721418 Liu, N. and Lasko, P. (2015). Analysis of RNA interference lines identifies new functions of maternally-expressed genes involved in embryonic patterning in Drosophila melanogaster. G3 (Bethesda). PubMed ID: 25834215 Ghosh, S and Lasko, P. (2015). Loss-of-function analysis reveals distinct requirements of the translation initiation factors eIF4E, eIF4E-3, eIF4G and eIF4G2 in Drosophila spermatogenesis. PLoS One 10: e0122519. PubMed ID: 25849588 Liu, N. and Lasko, P. (2015). Analysis of RNA interference lines identifies new functions of maternally-expressed genes involved in embryonic patterning in Drosophila melanogaster. G3 (Bethesda) [Epub ahead of print]. 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