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Bayer, C. A., von Kalm, L. and Fristrom, J. W. (1997). Relationships between protein isoforms and genetic functions demonstrate functional redundancy at the Broad-Complex during Drosophila metamorphosis. Dev. Biol. 187(2): 267-282.

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Brennan, C. A., et al. (2001). Broad-complex, but not Ecdysone receptor, is required for progression of the morphogenetic furrow in the Drosophila eye. Development 128: 1-11

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Dressel, U., et al. (1999). Alien, a highly conserved protein with characteristics of a corepressor for members of the nuclear hormone receptor superfamily. Mol. Cell. Biol. 19: 3383-3394.

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Dubrovsky, E. B., et al. (1996). The Broad-Complex gene is a tissue-specific modulator of the ecdysone response of the Drosophila hsp23 gene. Mol. Cell. Biol. 16: 6542-55

Dunne, J. C., Kondylis, V. and Rabouille, C. (2002). Ecdysone triggers the expression of golgi genes in Drosophila imaginal discs via Broad-Complex. Dev. Biol. 245: 172-186. 11969264

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Emery, I. F., Bedian, V. and Guild, G. M. (1994). Differential expression of Broad-Complex transcriptionfactors may forecast tissue-specific developmental fatesduring Drosophila metamorphosis. Development 120: 3275-3287

Fisk, G. J. and Thummel, C. S. (1998). The DHR78 nuclear receptor is required for ecdysteroid signaling during the onset of Drosophila metamorphosis. Cell 93(4): 543-555.

Fletcher, J. C. and Thummel, C. S. (1995).The ecdysone-inducible Broad-complex and E74 early genes interact to regulate target gene transcription and Drosophila metamorphosis. Genetics 141: 1025-1035

Fletcher, J. C., D'Avino, P. P. and Thummel, C. S. (1997). A steroid-triggered switch in E74 transcription factor isoforms regulates the timing of secondary-response gene expression. Proc. Natl. Acad. Sci. 94 (9): 4582-4586

Geneste, O., Copeland, J.W., and Treisman, R. (2002). LIM kinase and Diaphanous cooperate to regulate serum response factor and actin dynamics. J. Cell Biol. 157: 831-838. 12034774

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Ghbeish, N. and McKeown, M. (2002). Analyzing the repressive function of ultraspiracle, the Drosophila RXR, in Drosophila eye development. Mech. Dev. 111(1-2): 89-98. 11804781

Gotwals, P. J. and Fristrom, J. W. (1991). Three neighboring genes interact with the Broad-Complex and the Stubble-stubbloid locus to affect imaginal disc morphogenesis in Drosophila. Genetics 127: 747-59

Halsell, S. R. and Kiehart, D, P. (1998). Second-site noncomplementation identifies genomic regions required for Drosophila nonmuscle myosin function during morphogenesis. Genetics 148(4):1845-1863.

Hodgetts, R. B., et al. (1995). Hormonal induction of Dopa decarboxylase in the epidermis of Drosophila is mediated by the Broad-Complex. Development 121: 3913-3922

Huet, F., Puiz, C. and Richards, G. (1993). Puffs and PCR: the in vivo dynamics of early gene expression during ecdysone responses in Drosophila. Development 118: 613-627

Huynh, K. D. and Bardwell, V. J. (1998). The BCL-6 POZ domain and other POZ domains interact with the co-repressors N-CoR and SMRT. Oncogene 1998 Nov 12;17(19):2473-84.

Jiang, C., et al. (2000). A steroid-triggered transcriptional hierarchy controls salivary gland cell death during Drosophila metamorphosis. Molec. Cell 5: 445-455.

Johnson, F. B., Parker, E. and Krasnow, M. A. (1995). Extradenticle protein is a selective cofactor for the Drosophila homeotics: role of the homeodomain and YPWM amino acid motif in the interaction. Proc. Natl. Acad. Sci. 92: 739-743

Konopova, B. and Jindra, M. (2008). Broad-Complex acts downstream of Met in juvenile hormone signaling to coordinate primitive holometabolan metamorphosis. Development 135: 559-568. PubMed Citation: 18171683

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Karim, F. D., Guild, G. M. and Thummel, C. S. (1993). The Drosophila Broad-Complex plays a key role in controlling ecdysone-regulated gene expression at the onset of metamorphosis. Development 118: 977-988

Lam, G. T., Jiang, C., and Thummel, C. S. (1997). Coordination of larval and prepupal gene expression by the DHR3 orphan receptor during Drosophila metamorphosis. Development 124 (9): 1757-1769.

Lee, C.-Y. and Baehrecke, E. H. (2001). Steroid regulation of autophagic programmed cell death during development. Development 128: 1443-1455. 11262243

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Lehmann, M. and Korge, G. (1995). Ecdysone regulation of the Drosophila Sgs-4 gene is mediated by the synergistic action of ecdysone receptor and SEBP 3. EMBO J. 14: 716-726

Li, T.-R. and Bender, M. (2000). A conditional rescue system reveals essential functions for the ecdysone receptor( EcR) gene during molting and metamorphosis in Drosophila. Development 127: 2897-2905.

Li, X., et al. (1997). Overexpression, purification, characterization, and crystallization of the BTB/POZ domain from the PLZF oncoprotein. J. Biol. Chem. 272(43): 27324-27329

Lovato, T. L., Benjamin, A. R. and Cripps, R. M. (2005). Transcription of Myocyte enhancer factor-2 in adult Drosophila myoblasts is induced by the steroid hormone ecdysone. Dev. Biol. 288(2): 612-21. 16325168

Major, R. J. and Irvine, K. D. (2005). Influence of Notch on dorsoventral compartmentalization and actin organization in the Drosophila wing. Development 132(17): 3823-33. 16049109

Martin, D. N. and Baehrecke, E. H. (2004). Caspases function in autophagic programmed cell death in Drosophila. Development 131: 275-284. 14668412

Minakuchi, C., Zhou, X. and Riddiford, L. M. (2008). Krüppel homolog 1 (Kr-h1) mediates juvenile hormone action during metamorphosis of Drosophila melanogaster. Mech. Dev. 125(1-2): 91-105. PubMed citation: 18036785

Miura, K., Oda, M., Makita, S and Chinzei, Y. (2005). Characterization of the Drosophila Methoprene-tolerant gene product. FEBS J. 272: 1169-1178. 15720391

Mugat, B., et al. (2000). Dynamic expression of Broad-complex isoforms mediates temporal control of an ecdysteroid target gene at the onset of Drosophila metamorphosis. Dev. Bio. 227: 104-117.

Niu, H., Ye, B. H. and Dalla-Favera, R. (1998). Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factor. Genes Dev. 12(13): 1953-1961.

O'Keefe, S., Schouls, M. and Hodgetts, R. (1995). Epidermal cell-specific quantitation of dopa decarboxylase mRNA in Drosophila by competitive RT-PCR: an effect of Broad-Complex mutants. Dev. Genet. 1645: 77-84

Peri, F., Bokel, C. and Roth, S. (1999). Local gurken signaling and dynamic MAPK activation during Drosophila oogenesis. Mech. Dev. 81(1-2): 75-88.

Peri, F. and Roth, S. (2000). Combined activities of Gurken and Decapentaplegic specify dorsal chorion structures of the Drosophila egg. Development 127: 841-850.

Renault, N., King-Jones, K. and Lehmann, M. (2001). Downregulation of the tissue-specific transcription factor Fork head by Broad-Complex mediates a stage-specific hormone response. Development 128: 3729-3737. 11585799

Restifo, L. L. and White, K. (1991). Mutations in a steroid hormone-regulated gene disrupt the metamorphosis of the central nervous system in Drosophila. Dev. Biol. 148: 174-94

Restifo, L. L. and Merrill, V. K. (1994). Two Drosophila regulatory genes, Deformed and the Broad-Complex, share common functions in development of adult CNS, head, and salivary glands. Dev. Biol. 162: 465-485

Restifo, L. L. and Hauglum, W. (1998). Parallel molecular genetic pathways operate during CNS metamorphosis in Drosophila. Mol. Cell. Neurosci. 11: 134-48.

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Sandstrom, D. J., et al. (1997). Broad-Complex transcription factors regulate muscle attachment in Drosophila. Dev. Biol. 181: 168-185.

Sandstrom, D. J. and Restifo, L. L. (1999). Epidermal tendon cells require Broad Complex function for correct attachment of the indirect flight muscles in Drosophila melanogaster. J. Cell Sci. 112: 4051-4065.

Schubiger, M. and Truman, J. W. (2000). The RXR ortholog USP suppresses early metamorphic processes in Drosophila in the absence of ecdysteroids. Development 127: 1151-1159.

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Sempere, L. F., et al. (2003). Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and Broad-Complex gene activity. Dev. Biol. 259: 9-18. 12812784

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Sorrentino, R. P., Carton, Y. and Govind, S. (2002). Cellular immune response to parasite infection in the Drosophila lymph gland is developmentally regulated. Dev. Biol. 243: 65-80. 11846478

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Sugawara, M., et al. (1994). A factor that regulates the class II major histocompatibility complex gene DPA is a member of a subfamily of zinc finger proteins that includes a Drosophila developmental control protein. Mol. Cell. Biol. 14: 8438-8450

Suzuki, Y., Truman, J. M. and Riddiford, L. M. (2008). The role of Broad in the development of Tribolium castaneum: implications for the evolution of the holometabolous insect pupa. Development 135: 569-577. PubMed Citation: 18171684

Terashima, J. and Bownes, M. (2004). Translating available food into the number of eggs laid by Drosophila melanogaster. Genetics 167(4): 1711-9. 15342510

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von Kalm, L., et al. (1994). The Broad-Complex directly controls a tissue-specific response to the steroid hormone ecdysone at the onset of Drosophila metamorphosis. EMBO J. 13: 3505-3516

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date revised: 16 August 2008

 

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