Notch

PROTEIN INTERACTIONS
Table of Contents

page 1

General considerations
Notch interactions with its ligands
Signaling by Notch lacking a C-terminus

page 2

Notch and Kuzbanian
Notch interaction with Wingless
Notch modulates Wnt signalling by associating with Armadillo/ß-catenin and regulating its transcriptional activity
Notch interaction with Fringe
Notch modulation by O-fucosyltransferase 1 is essential for Notch interaction with its ligands and for Fringe function
Gfr is involved in the fucosylation of Notch-linked glycans
Distinct functional units of the Golgi complex in Drosophila cells as revealed by the distribution of Fringe connection - Notch and the Golgi complex
Notch interaction with Scabrous

page 3

Notch and Suppressor of Hairless
Geometry and protein interactions at Su(H) binding sites
Notch and Numb
Notch and Sanpodo
Notch and Dishevelled
Notch and Canoe
Notch and Shaggy
Notch and Deltex

page 4

Notch, Abl and Disabled
Notch and Notchless
Notch, Presenilin and Nicastrin
Notch cleavage by Furin
Notch and Mastermind
Nipped-A and Notch signaling

page 5

Warthog and trafficking of Notch
Lethal giant discs and Notch trafficking
Notch signaling at the wing margin is SNARE dependent
Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101,
       elicit non-cell-autonomous overgrowth caused by increased Notch-mediated signaling and ectopic expression
       of the Notch target gene unpaired
The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating Notch trafficking
Merlin and Expanded function cooperatively to modulate EGFR and Notch endocytosis and signaling
Protein degradation and Notch signaling

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