mastermind
Bettler, D., Schmid, A. and Yedvobnick, B. (1991). Early ventral expression of the Drosophila neurogenic locus mastermind. Dev. Biol. 144(2): 436-9
Bettler, D., Pearson, S. and Yedvobnick, B. (1996). The nuclear protein encoded by the Drosophila neurogenic gene mastermind is widely expressed and associates with specific chromosomal regions. Genetics 143(2): 859-875.
Brand, M. and Campos-Ortega, J.A. (1988). Two groups of interrelated genes regulate early neurogenesis in Drosophila melanogaster. Roux Arch. dev. Biol. 197: 457-470
Buescher, M., et al. (1998). Binary sibling neuronal cell fate decisions in the Drosophila embryonic central nervous system are nonstochastic and require inscuteable-mediated asymmetry of ganglion mother cells. Genes Dev. 12(12): 1858-1870.
Cave, J. W., Loh, F., Surpris, J. W., Xia, L. and Caudy, M. A. (2005). A DNA transcription code for cell-specific gene activation by notch signaling. Curr. Biol. 15(2): 94-104. 15668164
Endo, K., Aoki, T., Yoda, Y., Kimura, K. and Hama, C. (2007). Notch signal organizes the Drosophila olfactory circuitry by diversifying the sensory neuronal lineages. Nat. Neurosci. 10(2): 153-60. Medline abstract: 17220884
Fortini, M.E. and Artavanis-Tsakonas, S. (1994). The suppressor of Hairless protein participates in Notch receptor signaling. Cell 79: 273-282
Fryer, C. J., et al. (2002). Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex. Genes Dev. 16: 1397-1411. 12050117
Gause, M., Eissenberg, J. C., Macrae, A. F., Dorsett, M., Misulovin, Z., Dorsett, D. (2006). Nipped-A, the Tra1/TRRAP subunit of the Drosophila SAGA and Tip60 complexes, has multiple roles in Notch signaling during wing development. Mol. Cell. Biol. 26(6): 2347-59. 16508010
Giraldez, A. J. Perez, L. and Cohen, S. M. (2002). A naturally occurring alternative product of the mastermind locus that represses Notch signaling. Mech. Dev. 115: 101-105. 12049771
Go, M. J. and Artavanis-Tsakonas, S. (1998). A genetic screen for novel components of the Notch signaling pathway during Drosophila bristle development. Genetics 150(1): 211-220
Hartenstein, A.Y., Rugendorff, A., Tepass, U. and Hartenstein, V. (1992). The function of the neurogenic genes during epithelial development in the Drosophila embryo. Development 116(4): 1203-20
Helms, W., et al. (1999). Engineered truncations in the Drosophila Mastermind protein disrupt Notch pathway function. Dev. Biol. 215(2): 358-374
Jagla, T., et al. (1998). ladybird determines cell fate decisions during diversification of Drosophila somatic muscles. Development 125(18): 3699-3708.
Kitagawa, M., et al. (2001). A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters. Mol. Cell. Biol. 21(13): 4337-46. 11390662
Kovalick, G.E. and Beckingham, K. (1992). Calmodulin transcription is limited to the nervous system during Drosophila embryogenesis. Dev. Biol. 150(1): 33-46
Lamar, E., et al. (2001). Nrarp is a novel intracellular component of the Notch signaling pathway. Genes Dev. 15: 1885-1899. 11485984
Lieber, T., et al. (1993). Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes Dev. 7: 1949-1965
Martin-Bermudo, M.D., Carmena, M. and Jimenez, F. (1995). Neurogenic genes control gene expression at the transcriptional level in early neurogenesis and in mesectoderm specification. Development 121: 219-224
Morcillo, P., Rosen, C. and Dorsett, D. (1996). Genes regulating the remote wing margin enhancer in the Drosophila cut locus. Genetics 144(3): 1143-1154.
Morcillo, P., et al. (1997). Chip, a widely expressed chromosomal protein required for segmentation and activity of a remote wing margin enhancer in Drosophila. Genes Dev. 11(20):2729-2740.
Nam, Y., Sliz, P., Song, L., Aster, J. C. and Blacklow, S. C. (2006). Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes. Cell 124(5): 973-83. 16530044
Nam, Y., et al. (2007). Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription. Proc. Natl. Acad. Sci. 104: 2103-2108. Medline abstract: 17284587
Newfeld, S.J., Smoller, D.A. and Yedvobnick, B. (1991). Interspecific comparison of the unusually repetitive Drosophila locus mastermind. J. Mol. Evol. 32(5): 415-20
Peng, C.-Y., et al. (2007). Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord. Neuron 53: 813-827. Medline abstract: 17359917
Petcherski, A. G. and Kimble, J. (2000). Mastermind is a putative activator for Notch. Curr. Biol. 10: R471-R473
Prout, M., et al. (1997). Autosomal mutations affecting adhesion between wing surfaces in Drosophila melanogaster. Genetics 146(1): 275-285.
Rusconi, J. C. and Corbin, V. (1999). A widespread and early requirement for a novel Notch function during Drosophila embryogenesis. Dev. Biol. 215(2): 388-398
Schuldt, A. J. and Brand, A. H. (1999). Mastermind acts downstream of Notch to specify neuronal cell fates in the Drosophila central nervous system. Dev. Biol. 205(2): 287-295.
Skeath, J. B. and Doe, C. Q. (1998). Sanpodo and Notch act in opposition to Numb to distinguish sibling neuron fates in the Drosophila CNS. Development 125: 1857-1865.
Smoller, D.A., Friedel, C., Schmid, A., Bettler, D., Lam, L. and Yedvobnick, B. (1990). The Drosophila neurogenic locus mastermind encodes a nuclear protein unusually rich in amino acid homopolymers. Genes & Dev. 4(10): 1688-1700
Udolph, G., Rath, P. and Chia, W. (2001). A requirement for Notch in the genesis of a subset of glial cells in the Drosophila embryonic central nervous system which arise through asymmetric divisions. Development 128: 1457-1466. 11262244
Wilson, J. J. and Kovall, R. A. (2006). Crystal structure of the CSL-Notch-Mastermind ternary complex bound to DNA. Cell 124(5): 985-96. 16530045
Wu, L., et al. (2000). MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors. Nat. Genet. 26(4): 484-9. 11101851
Yedvobnick, B., et al. (2004). Differential effects of Drosophila Mastermind on asymmetric cell fate specification and neuroblast formation. Genetics 166: 1281-1289. 15082547
date revised: 30 March 2008
Home page: The Interactive Fly © 1997 Thomas B. Brody, Ph.D.
The Interactive Fly resides on the
Society for Developmental Biology's Web server.