The Radish protein is similar to a predicted protein from the mosquito Anopheles gambiae (66% identity) and to one from the honey bee Apis mellifera (45% identity). It has no striking homology to proteins with known function. Sequence comparison with mammalian proteins reveals low homology (25%) to Arg/Ser-rich splicing factors. 29% of amino acids in the Radish protein are either arginines (14%) or serines (15%) (Folkers, 2006).

The inferred Radish amino acid sequence has 23 potential PKA and 14 protein PKC phosphorylation sites. The Radish sequence also has five bipartite nuclear localization signals (NLSs); and each NLS overlaps with a PKA target site. The truncated protein in the radish mutant lacks two PKA target sequences and two NLSs (Folkers, 2006).

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