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Jinks, T. M., et al. (2000). The JAK/STAT signaling pathway is required for the initial choice of sexual identity in Drosophila melanogaster. Molec. Cell 5: 581-587

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Luo, H., et al. (1997). Mutation in the Jak Kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways. Mol. Cell. Biol. 17: 1562-71

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Marrero, M. B., et al. (1997). Role of janus Kinase/Signal transducer and activator of transcription and mitogen-activated protein kinase cascades in angiotensin II- and platelet-derived growth factor-induced vascular smooth muscle cell proliferation. J. Biol. Chem. 272(39): 24684-24690.

McGregor, J. B., Xi, R. and Harrison, D. A. (2002). JAK signaling is somatically required for follicle cell differentiation in Drosophila. Development 129: 705-717. 11830571

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Mukherjee, T., Schäfer, U. and Zeidler, M. P. (2006). Identification of Drosophila genes modulating janus kinase/signal transducer and activator of transcription signal transduction. Genetics 172(3): 1683-97. PubMed citation: 16387886

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Parganas E., et al. (1998). Jak2 is essential for signaling through a variety of cytokine receptors. Cell 93(3): 385-395.

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Rodig, S. J., et al. (1998). Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses. Cell 93(3): 373-383.

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Shi, S., et al. (2006). JAK signaling globally counteracts heterochromatic gene silencing. Nat. Genet. 38(9): 1071-6. Medline abstract: 16892059

Silver, D. L. and Montell, D. J. (2001). Paracrine signaling through the JAK/STAT pathway activates invasive behavior of ovarian epithelial cells in Drosophila. Cell 107: 831-841. 11779460

Small, S., Blair, A. and Levine, M. (1996). Regulation of two pair-rule stripes by a single enhancer in the Drosophila embryo. Dev. Biol. 175: 314-324

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Sorrentino, R. P., Melk, J. P. and Govind, S. (2004). Genetic analysis of contributions of dorsal group and JAK-Stat92E pathway genes to larval hemocyte concentration and the egg encapsulation response in Drosophila. Genetics 166: 1343-1356. 15082553

Takemoto, S., et al. (1997). Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins. Proc. Natl. Acad. Sci. 94(25): 13897-13902.

Torres, P. L., López-Schier, H. and St Johnston, D. (2003). A Notch/Delta-dependent relay mechanism establishes anterior-posterior polarity in Drosophila. Dev. Cell 5: 547-558. 14536057

Xi, R., McGregor, J. R. and Harrison, D. A. (2003). A gradient of JAK pathway activity patterns the anterior-posterior axis of the follicular epithelium. Dev. Cell 4: 167-177. 12586061

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Yan, R., et al. (1996a). Identification of a STAT gene that functions in Drosophila development. Cell 84: 421-30

Yan, R., et al. (1996b). A JAK-STAT pathwar regulates wing vein formation in Drosophila. Proc. Natl. Acad. Sci. 93: 5842-47

Yasukawa, H., et al. (1999). The JAK-binding protein JAB inhibits janus tyrosine kinase activity through binding in the activation loop. EMBO J. 18(5): 1309-20.

Zeidler, M. P., Perrimon, N. and Strutt, D. I. (1999a). Polarity determination in the Drosophila eye: a novel role for Unpaired and JAK/STAT signaling. Genes Dev. 13: 1342-1353.

Zeidler, M. P., Perrimon, N. and Strutt, D. I. (1999b). The four-jointed gene is required in the Drosophila eye for ommatidial polarity specification. Curr. Biol. 9: 1363-1372.

Zhang X. F., et al. (2001). Janus kinase 2 is involved in stromal cell-derived factor-1alpha-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells. Blood 97: 3342-3348. 11369622

Zhao, S., et al. (2002). JAK2, complemented by a second signal from c-kit or flt-3, triggers extensive self-renewal of primary multipotential hemopoietic cells. EMBO J. 21: 2159-2167. 11980713

Zhou, Y. J., et al. (1997). Distinct tyrosine phosphorylation sites in JAK3 kinase domain positively and negatively regulate its enzymatic activity. Proc. Natl. Acad. Sci. 94(25): 13850-13855.

Zhu, X., et al. (1997). Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase. Mol. Cell. Biol. 17(11): 6618-6623.

date revised: 20 June 2008 

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