Djun
Agarwal, S., Corbley, M. J., and Roberts, T. M. (1995). Reconstitution of signal transduction from the membrane to the nucleus in a baculovirus expression system: activation of Raf-1 leads to hypermodification of c-jun and c-fos via multiple pathways. Oncogene 11: 427-438. PubMed Citation: 7543194
Agarwal, S. K., et al. (1999). Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription. Cell 96(1): 143-52. PubMed Citation: 9989505
Bakiri, L., et al. (2000). Cell cycle-dependent variations in c-Jun and JunB phosphorylation: a role in the control of cyclin D1 expression. EMBO J. 19: 2056-2068. PubMed Citation: 10790372
Barila, D., et al. (2000). A nuclear tyrosine phosphorylation circuit: c-Jun as an activator and substrate of c-Abl and JNK. EMBO J. 19: 273-281. PubMed Citation: 10637231
Bates, K. L., Higley, M. and Letsou, A. (2008). Raw mediates antagonism of AP-1 activity in Drosophila. Genetics 178(4): 1989-2002. PubMed Citation: 18430930
Behrens, A., Sibilia, M. and Wagner, E. F. (1999). Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation. Nat. Genet. 21(3): 326-9. PubMed Citation: 10080190
Behrens, A., et al. (2002). Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver. EMBO J. 21: 1782-1790. 11927562
Behrens, A., et al. (2003). Impaired intervertebral disc formation in the absence of Jun. Development 130(1): 103-9. 12441295
Blake, K. J., Myette, G. and Jack, J. (1998). The products of ribbon and raw are necessary for proper cell shape and cellular localization of nonmuscle myosin in Drosophila. Dev. Biol. 203: 177-188. PubMed Citation: 9806782
Blake, K. J., Myette, G. and Jack, J. (1999). ribbon, raw, and zipper have distinct functions in reshaping the Drosophila cytoskeleton. Dev. Genes Evol. 209: 555-559. PubMed Citation: 10502112
Blank, U., Brown, A., Adams, D. C., Karolak, M. J. and Oxburgh, L. (2009). BMP7 promotes proliferation of nephron progenitor cells via a JNK-dependent mechanism. Development 136(21): 3557-66. PubMed Citation: 19793891
Blatow M, et al. (2003). Ca2+ buffer saturation underlies paired pulse facilitation in calbindin-D28k-containing terminals. Neuron 38: 79-88. PubMed Citation: 12691666
Bohmann, D., et al. (1994). Drosophila Jun mediates Ras-dependent photoreceptor determination. Cell 78: 973-986. PubMed Citation: 7923366
Borchiellini, C., Coulon, J. and Le Parco, Y. (1996). The function of type IV collagen during Drosophila embryogenesis. Wilhelm Roux's Arch. Dev. Biol. 205: 468-475
Bossis, G., et al. (2005). Down-regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation. Mol. Cell. Biol. 25(16): 6964-79. 16055710
Boutros, M., et al. (1998). Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling. Cell 94(1): 109-118. PubMed Citation: 9674432
Busygina, V., et al. (2004). Hypermutability in a Drosophila model for multiple endocrine neoplasia type 1. Hum. Mol. Genet. 13: 2399-2408. Medline abstract: 15333582
Byars, C. L., Bates, K. L. and Letsou, A. (1999). The dorsal-open group gene raw is required for restricted DJNK signaling during closure. Development 126(21): 4913-23. PubMed Citation: 10518507
Campos, I., et al. (2010). Genetic screen in Drosophila melanogaster uncovers a novel set of genes required for embryonic epithelial repair. Genetics 184(1): 129-40. PubMed Citation: 19884309
Caelles, C., et al. (1997). Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway. Genes Dev. 11(24): 3351-3364. PubMed Citation: 9407028
Cerrato, A., et al. (2006). Genetic interactions between Drosophila melanogaster menin and Jun/Fos. Dev. Biol. 298(1): 59-70. Medline abstract: 16930585
Chong, J. A., et al. (1995). REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons. Cell 80: 949-957. PubMed Citation: 7697725
Ciapponi, L. and Bohmann, D. (2002). An essential function of AP-1 heterodimers in Drosophila development. Mech. Dev. 115: 35-40. 12049765
Claret, F.-X., et al. (1996). A new group of conserved coactivators that increase the specificity of AP-1 transcription factors. Nature 383: 453-457
Clarke, N., et al. (1998). Epidermal growth factor induction of the c-jun promoter by a Rac pathway. Mol. Cell. Biol. 18(2): 1065-1073. PubMed Citation: 9448004
Clayton, A. L., et al. (2000). Phosphoacetylation of histone H3 on c-fos- and c-jun-associated nucleosomes upon gene activation. EMBO J. 19: 3714-3726. PubMed Citation: 10899125
Cook, S. J., Aziz, N. and McMahon, M. (1999). The repertoire of Fos and Jun proteins expressed during the G1 phase of the cell cycle is determined by the duration of mitogen-activated protein kinase activation. Mol. Cell. Biol. 19(1): 330-41. PubMed Citation: 9858557
Cruzalegui, F. H., Hardingham, G. E. and Bading, H. (1999). c-Jun functions as a calcium-regulated transcriptional activator in the absence of JNK/SAPK1 activation. EMBO J. 18(5): 1335-44. PubMed Citation: 10064599
Davies, C. C., et al. (2010). Identification of a co-activator that links growth factor signalling to c-Jun/AP-1 activation. Nat. Cell Biol. 12(10): 963-72. PubMed Citation: 20852630
de Groot, R. P., et al. (1993). Negative regulation of Jun/AP-1: conserved function of glycogen synthase kinase 3 and the Drosophila kinase shaggy. Oncogene 8: 841-7. PubMed Citation: 8384355
Delgado, R, et al. (2000). Size of vesicle pools, rates of mobilization, and recycling at neuromuscular synapses of a Drosophila mutant, shibire. Neuron 28: 941-953. PubMed Citation: 11163278
Efer, R., et al. (2003). Liver tumor development: c-jun antagonizes the proapoptotic activity of p53. Cell 112: 181-192. 12553907
Fang, X., et al. (1997). Lysophosphatidylcholine stimulates activator protein 1 and the c-Jun N-terminal kinase activity. J. Biol. Chem. 272 (21): 13683-13689. PubMed Citation: 9153219
Faris, M., et al. (1998). Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter. Mol. Cell. Biol. 18(9): 5414-24. PubMed Citation: 9710625
Franciscovich, A. L., Mortimer, A. D., Freeman, A. A., Gu, J. and Sanyal, S. (2008). Overexpression screen in Drosophila identifies neuronal roles of GSK-3 beta/shaggy as a regulator of AP-1-dependent developmental plasticity. Genetics 180(4): 2057-71. PubMed Citation: 18832361
Gaiddon, C., Loeffler, J. P., and Larmet, Y. (1996). Brain-derived neurotrophic factor stimulates AP-1 and cyclic AMP-responsive element dependent transcriptional activity in central nervous system neurons. J. Neurochem. 66: 2279-2286. PubMed Citation: 8632149
Geles, K. G., Freiman, R. N., Liu, W. L., Zheng, S., Voronina. E. and Tjian, R. (2006). Cell-type-selective induction of c-jun by TAF4b directs ovarian-specific transcription networks. Proc. Natl. Acad. Sci. 103(8): 2594-9. 16473943
Gerald, D., et al. (2004). JunD reduces tumor angiogenesis by protecting cells from oxidative stress. Cell 118(6): 781-94. 15369676
Gritzan, U., Weiss, C., Brennecke, J. and Bohmann, D. (2002). Transrepression of AP-1 by nuclear receptors in Drosophila. Mech. Dev. 115: 91-100. 12049770
Grotewold, L. and Rüther, U. (2002). The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death. EMBO J. 21: 966-975. 11867524
Groupp, E. R. and Donovan-Peluso, M. (1997). Lipopolysaccharide induction of THP-1 cells activates binding of c-Jun, Ets, and Egr-1 to the tissue factor promoter. J. Biol. Chem. 271(21): 12423-12430. PubMed Citation: 8647847
Han, T. H. and Prywes, R. (1995). Regulatory role of MEF2D in serum induction of the c-jun promoter. Mol. Cell. Biol. 15 (6): 2907-2915. PubMed Citation: 7760790
Han, Z. S., et al. (1998). A conserved p38 mitogen-activated protein kinase pathway regulates Drosophila immunity gene expression. Mol. Cell. Biol. 18(6): 3527-39. PubMed Citation: 9584193
Hartwig, C. L., et al. (2009). Normal dendrite growth in Drosophila motor neurons requires the AP-1 transcription factor. Dev. Neurobiol. 68(10): 1225-1242. PubMed Citation: 18548486
Herzog, K. H., Chen, S. C. and Morgan, J. I. (1999). c-jun is dispensable for developmental cell death and axogenesis in the retina. J. Neurosci. 19(11): 4349-59. PubMed Citation: 10341238
Hooper, C., et al. (2007). Glycogen synthase kinase-3 inhibition is integral to long-term potentiation. Eur. J. Neurosci. 25: 81-86. PubMed Citation: 17241269
Hou, X. S., Goldstein, E. S. and Perrimon, N. (1997). Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway to the Decapentaplegic signal transduction pathway in regulating epithelial cell sheet movement. Genes Dev. 11:1728-1737. PubMed Citation: 9224721
Ivanov, V. N., et al. (2001). Cooperation between STAT3 and c-Jun suppresses Fas transcription. Molec. Cell 7: 517-528. PubMed Citation: 11463377
Isaksson, A., et al. (1997). The deubiquitination enzyme fat facets negatively regulates RTK/Ras/MAPK signalling during Drosophila eye development. Mech. Dev. 68(1-2): 59-67. PubMed Citation: 9431804
Kardassis, D., et al. (1999). c-Jun transactivates the promoter of the human p21WAF1/Cip1 gene by acting as a superactivator of the ubiquitous transcription factor Sp1. J. Biol. Chem. 274: 29572-29581. PubMed Citation: 10506225
Karin, M. (1995). The regulation of AP-1 activity by mitogen-activated protein kinases. J. Biol. Chem. 270: 16483-6. PubMed Citation: 7622446
Kassel, O., et al. (2004). A nuclear isoform of the focal adhesion LIM-domain protein Trip6 integrates activating and repressing signals at AP-1- and NF-kappaB-regulated promoters. Genes Dev. 18: 2518-2528. 15489293
Kawasaki, H., et al. (1998). p300 and ATF-2 are components of the DRF complex, which regulates retinoic acid- and E1A-mediated transcription of the c-jun gene in F9 cells. Genes Dev. 12: 233-245. PubMed Citation: 9436983
Kerppola, T. K. and Curran, T. (1997). The transcription activation domains of Fos and Jun induce DNA bending through electrostatic interactions. EMBO J. 16: 2907-16. PubMed Citation: 9184234
Kim, S. M., et al. (2009). Fos and Jun potentiate individual release sites and mobilize the reserve synaptic-vesicle pool at the Drosophila larval motor synapse. Proc. Natl. Acad. Sci. 106(10): 4000-4005. PubMed Citation: 19228945
Kim, T., Yoon, Y., Cho, H., Lee, W-B., Kim, J., Song, Y-H., Kim, S.N., Yoon, J.H., Kim-Ha, J. and Kim, Y-J. (2005). Downregulation of lipopolysaccharide response in Drosophila by negative crosstalk between the AP-1 and the NF-kappaB signaling modules. Nat. Immunol. 6: 211-218. 15640802
Knochel, S., Schuler-Metz, A. and Knochel, W. (2000). c-Jun (AP-1) activates BMP-4 transcription in Xenopus embryos. Mech. Dev. 98: 29-36. PubMed Citation: 11044605
Kockel, L., et al. (1997). Jun in Drosophila development: redundant and nonredundant functions and regulation by two MAPK signal transduction pathways. Genes Dev. 11: 1748-1758. PubMed Citation: 9224723
Kralova, J., et al. (1996). Synergistic stimulation of avian IkappaBalpha transcription by rel and fos/jun factors. Oncogene 12: 2595-2604. PubMed Citation: 8700518
Kramer, B., Wiegmann, K. and Kronke, M. (1995). Regulation of the human TNF promoter by the transcription factor Ets. J Biol Chem 270: 6577-6583. PubMed Citation: 7896795
Kallunki, T., et al. (1996). cJun can recruit JNK to phosphorylate dimerization partners via specific docking interactions. Cell 87: 929-939. PubMed Citation: 8945519
Lamb, J. A., et al. (2003). JunD mediates survival signaling by the JNK signal transduction pathway. Molec. Cell 11: 1479-1489. 12820962
Leppa, S., et al. (1998). Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation. EMBO J. 17: 4404-4413
Li, G., et al. (2003). c-Jun is essential for organization of the epidermal leading edge. Dev. Cell 4: 865-877. 12791271
Liberati, N. T., et al. (1999). Smads bind directly to the jun family of AP-1 transcription factors. Proc. Natl. Acad. Sci. 96(9): 4844-9. PubMed Citation: 10220381
Liu, W. L., et al. (2009). Structures of three distinct activator-TFIID complexes. Genes Dev. 23(13): 1510-21. PubMed Citation: 19571180
Lively, T. N., Nguyen, T. N., Galasinski, S. K. and Goodrich, J. A. (2004). The basic leucine zipper domain of c-Jun functions in transcriptional activation through interaction with the N terminus of human TATA-binding protein-associated factor-1 (human TAF(II)250). J. Biol. Chem. 279(25): 26257-65. Medline abstract: 15087451
Macian, F., García-Rodriguez, C. and Rao, A.2 (2000). Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun. EMBO J. 19: 4783-4795
Malliri, A., et al. (1998). The transcription factor AP-1 Is required for EGF-induced activation of Rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells. J. Cell Biol. 143(4): 1087-1099
Marinissen, M. J., et al. (1999). A network of mitogen-activated protein kinases links G protein-coupled receptors to the c-jun promoter: a role for c-Jun NH2-terminal kinase, p38s, and extracellular signal-regulated kinase 5. Mol. Cell Biol. 19(6): 4289-301
Martin-Blanco, E., et al. (1998). puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila Genes Dev. 12: 557-570. PubMed Citation: 9472024
May, G. H. W., et al. (1998). An oncogenic mutation uncouples the v-Jun oncoprotein from positive regulation by the SAPK/JNK pathway in vivo. Curr. Biol. 8(2): 117-120
McDonough, P. M., et al. (1997). Collaborative roles for c-Jun N-terminal kinase, c-Jun, Serum response factor, and Sp1 in calcium-regulated myocardial gene expression. J. Biol. Chem. 272(38): 24046-24053
Mettouchi, A., et al. (1997). The c-Jun-indued transformation process involves complex regulation of Tenascin-C expression. Mol. Cell. Biol. 17: 3202-3209
Malliri, A., et al. (1998). The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells. J. Cell Biol. 143(4): 1087-99
Mechta-Grigoriou, F., et al. (2003). c-jun regulation and function in the developing hindbrain. Dev. Biol. 258: 419-431. 12798298
Mihaly, J., et al. (2001). The role of the Drosophila TAK homologue dTAK during development. Mech. Dev. 102(1-2): 67-79. 11287182
Miotto, B., Sagnier, T., Berenger, H., Bohmann, D., Pradel, J. and Graba, Y. (2005). Chameau HAT and DRpd3 HDAC function as antagonistic cofactors of JNK/AP-1-dependent transcription during Drosophila metamorphosis. Genes Dev. 20(1): 101-12. 16391236
Monnier, D. and Loeffler, J. P. (1998). Pituitary adenylate cyclase-activating polypeptide stimulates proenkephalin gene transcription through AP1- and CREB-dependent mechanisms. DNA Cell Biol. 17(2): 151-159
Murthy, V. N. and Stevens, C. F. (1999). Reversal of synaptic vesicle docking at central synapses. Nat Neurosci. 2: 503-507. PubMed Citation: 10448213
Naumann M., Bech-Otschir D., Huang X., Ferrell K. and Dubiel W. (1999). COP9 signalosome-directed c-Jun activation/stabilization is independent of JNK. J. Biol. Chem. 274: 35297-35300. 10585392
Nead, N. A., et al. (1998). Rb binds c-Jun and activates transcription. EMBO J. 17: 2342-2352. PubMed Citation: 9545246
Ng, K. W., et al. (1997). The binding of a Fos/Jun heterodimer can completely disrupt the structure of a nucleosome. EMBO J. 16: 2072-85. PubMed Citation: 9155033
Ogryzko, V. V., et al. (1996). The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 87: 953-959. PubMed Citation: 8945521
Oren, A., et al. (1999). The cytoskeletal network controls c-Jun expression and glucocorticoid receptor transcriptional activity in an antagonistic and cell-type-specific manner. Mol. Cell. Biol. 19(3): 1742-50. PubMed Citation: 10022861
O'Shaughnessy, R. F., Welti, J. C., Sully, K. and Byrne, C. (2009). Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development. Development 136(20): 3423-31. PubMed Citation: 19762425
Ouwens, D. M., et al. (2002). Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38. EMBO J. 21: 3782-3793. 12110590
Papaconstantinou, M., et al. (2005). Menin is a regulator of the stress response in Drosophila melanogaster, Mol. Cell. Biol. 25: 9960-9972. Medline abstract: 16260610
Passegue, E., Wagner, E. F. and Weissman, I. L. (2004). JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells. Cell 119(3): 431-43. 15507213
Peineau, S., et al. (2007). LTP inhibits LTD in the hippocampus via regulation of GSK3beta. Neuron 53: 703-717. PubMed Citation: 17329210
Perkins, K. K., Dailey, G. M. and Tjian, R. (1988). Novel Jun- and Fos-related proteins in Drosophila are functionally homologous to enhancer factor AP-1. EMBO J. 7: 4265-73. PubMed Citation: 3149584
Perkins, K. K., et al. (1990). The Drosophila Fos-related AP-1 protein is a developmentally regulated transcription factor. Genes Dev 4: 822-34. PubMed Citation: 2116361
Peverali, F. A., et al. (1996). Phosphorylation of Drosophila Jun by the MAP kinase Rolled regulates photoreceptor differentiation. EMBO J. 15: 3943-50. PubMed Citation: 8670899
Rajaram, N. and Kerppola, T. K. (1997). DNA bending by Fos-Jun and the orientation of heterodimer binding depend on the sequence of the AP-1 site. EMBO J 16 (10): 2917-2925
Rasse, T. M., et al. (2005) Glutamate receptor dynamics organizing synapse formation in vivo. Nat. Neurosci. 8: 898-905. PubMed Citation: 16136672
Ricci, R., et al. (2005). Distinct functions of junD in cardiac hypertrophy and heart failure. Genes Dev. 19: 208-213. 15655111
Riesgo-Escovar, J. R. and Hafen, E. (1997a). Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure. Genes Dev. 11:1717-1727. PubMed Citation: 9224720
Riesgo-Escovar, J. R. and Hafen, E. (1997b). Common and distinct roles of DFos and DJun during Drosophila development. Science 278(5338): 669-672. PubMed Citation: 9381174
Sanyal, S., et al. (2002). AP-1 functions upstream of CREB to control synaptic plasticity in Drosophila. Nature 416: 870-874. PubMed Citation: 11976688
Schoenherr, C. J. and Anderson, D. J. (1995). The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes. Science 267: 1360-1363. PubMed Citation: 7871435
Scholz, H., et al. (1997). Control of midline glia development in the embryonic Drosophila. Mech. Dev. 62: 79-91. PubMed Citation: 9106169
Schreiber, M., et al. (1999). Control of cell cycle progression by c-Jun is p53 dependent. Genes Dev. 13(5): 607-619. PubMed Citation: 10072388
See, R. H. and Shi, Y. (1998). Adenovirus E1B 19,000-molecular-weight protein activates c-Jun N-terminal kinase and c-Jun-mediated transcription. Mol. Cell. Biol. 18(7): 4012-4022. PubMed Citation: 9632786
Sekyrova, P., Bohmann, D., Jindra, M. and Uhlirova, M. (2010). Interaction between Drosophila bZIP proteins Atf3 and Jun prevents replacement of epithelial cells during metamorphosis. Development 137(1): 141-50. PubMed Citation: 20023169
Shaulian, E., et al. (2000). The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest. Cell 103: 897-907. PubMed Citation: 11136975
Shimizu, M., et al. (1998). Activation of the rat cyclin a promoter by ATF2 and Jun family members and its suppression by ATF4. Exp. Cell Res. 239(1): 93-103. PubMed Citation: 9511728
Sitlani, A. and Crothers, D. M. (1998). DNA-binding domains of Fos and Jun do not induce DNA curvature: An investigation with solution and gel methods. Proc. Natl. Acad. Sci. 95(4): 1404-1409. PubMed Citation: 9465027
Stronach, B. and Perrimon, N. (2002). Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper. Genes Dev. 16: 377-387. 11825878
Su, Y.-C., Treisman, J. E. and Skolnik, E. Y. (1998). The Drosophila Ste20-related kinase misshapen is required for embryonic dorsal closure and acts through a JNK MAPK module on an evolutionarily conserved signaling pathway. Genes Dev. 12: 2371-2380. PubMed Citation: 9694801
Suzanne, M., Perrimon, N. and Noselli, S. (2001). The Drosophila JNK pathway controls the morphogenesis of the egg dorsal appendages and micropyle. Dev. Bio. 237: 282-294. 11543614
Szabowski, A., et al. (2000). c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin. Cell 103: 745-755. PubMed Citation: 11114331
Szuts, D. and Bienz, M. (2000). LexA chimeras reveal the function of Drosophila Fos as a context-dependent transcriptional activator. Proc. Natl. Acad. Sci. 97: 5351-5356. PubMed Citation: 10805795
Thépot, D., et al. (2000). Targeted disruption of the murine junD gene results in multiple defects in male reproductive function. Development 127: 143-153. PubMed Citation: 10654608
Treier, M., Bohmann, D. and Mlodzik, M. (1995). JUN cooperates with the ETS domain protein pointed to induce photoreceptor R7 fate in the Drosophila eye. Cell 83: 753-760. PubMed Citation: 8521492
Tsuda, L., et al. (2006). An NRSF/REST-like repressor downstream of Ebi/SMRTER/Su(H) regulates eye development in Drosophila. EMBO J. 25(13): 3191-202. PubMed Citation: 16763555
Vallone, D., et al. (1997). Neoplastic transformation of rat thyroid cells requires the junB and fra-1 gene induction which is dependent on the HMGI-C gene product. EMBO J. 16(17): 5310-5321
Verstreken, P., et al. (2005). Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions. Neuron 47: 365-378. PubMed Citation: 16055061
Wang, G. L. and Goldstein, E. S. (1994). Transcription of DJun from D. melanogaster is positively regulated by DTF-1, AP-1, and CREB binding sites. Exp. Cell Res. 214: 389-399
Watson, A., et al. (1998). Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons. J. Neurosci. 18(2): 751-762
Weber, U., Paricio, N. and Mlodzik, M. (2000). Jun mediates Frizzled-induced R3/R4 cell fate distinction and planar polarity determination in the Drosophila eye. Development 127: 3619-3629. PubMed Citation: 10903185
Weitzman, J. B., et al. (2000). JunD protects cells from p53-dependent senescence and apoptosis. Mol. Cell 6: 1109-1119.
Westbrook, T. F., et al. (2005). A genetic screen for candidate tumor suppressors identifies REST. Cell 121: 837-848. PubMed Citation: 15960972
Westermarck, J., et al. (2002). The DEXD/H-box RNA helicase RHII/Gu is a co-factor for c-Jun-activated transcription. EMBO J. 21: 451-460. 11823437
Whitfield, J., et al. (2001). Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial Cytochrome c release. Neuron 29: 629-643. 11301023
Wisdom, R., Johnson, R. S. and Moore, C. (1999). c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms. EMBO J. 18(1): 188-97
Wollnik, F., et al. (1995). Block of c-Fos and JunB expression by antisense oligonucleotides inhibits light-induced phase shifts of the mammalian circadian clock. Eur. J. Neurosci. 7(3): 388-93
Wong, C., et al. (1999). Smad3-smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta. Mol. Cell. Biol. 19(3): 1821-30
Yao, J., et al. (1997). Lipopolysaccharide induction of the tumor necrosis factor-alpha promoter in human monocytic cells. Regulation by Egr-1, c-Jun, and NF-kappaB transcription factors. J. Biol. Chem. 272(28): 17795-17801
Yi, C. H., et al. (2007). A genome-wide RNAi screen reveals multiple regulators of caspase activation. J. Cell Biol. 179: 619-626. PubMed Citation: 17998402
Zagariya, A., et al. (1998). Tumor necrosis factor alpha gene regulation: enhancement of C/EBPbeta-induced activation by c-Jun. Mol. Cell. Biol. 8(5): 2815-2824
Zakharenko, S. S., et al. (2003). Presynaptic BDNF required for a presynaptic but not postsynaptic component of LTP at hippocampal CA1-CA3 synapses. Neuron 39: 975-990. PubMed Citation: 12971897
Zanger, K. Radovick, S. and Wondisford, F. E. (2001). CREB binding protein recruitment to the transcription complex requires growth factor-dependent phosphorylation of its GF box. Molec. Cell 7: 551-558
Zenz, R., et al. (2003). c-Jun regulates eyelid closure and skin tumor development through EGFR signaling. Dev. Cell 4: 879-889. 12791272
Zhang, K., et al. (1990). Drosophila homolog of the mammalian jun oncogene is expressed during embryonic development and activates transcription in mammalian cells. Proc Natl Acad Sci 87: 6281-5. PubMed Citation: 1696724
Zhang, Y., Feng, X. H. and Derynck, R. (1998). Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription. Nature 394: 909-913
Zhu, L. Q., et al. (2007). Activation of glycogen synthase kinase-3 inhibits long-term potentiation with synapse-associated impairments. J. Neurosci. 27: 12211-12220. PubMed Citation: 17989287
Zucker, R. S. and Regehr, W. G. (2002). Short-term synaptic plasticity. Annu. Rev. Physiol. 64: 355-405. PubMed Citation: 11826273
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