branchless


REFERENCES (part 1/2)

Abu-Issa, R., et al. (2002). Fgf8 is required for pharyngeal arch and cardiovascular development in the mouse. Development 129: 4613-4625. 12223417

Agarwal, P., et al. (2003). Tbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryo. Development 130: 623-633. 12490567

Ahmad, S. M. and Baker, B. S. (2002). Sex-specific deployment of FGF signaling in Drosophila recruits mesodermal cells into the male genital imaginal disc. Cell 109: 651-661. 12111457

Alappat, S. R., et al. (2004). The cellular and molecular etiology of the cleft secondary palate in Fgf10 mutant mice. Dev. Biol. 277: 102-113. 15572143

Alarid, E. T., et al. (1994). Keratinocyte growth factor functions in epithelial induction during seminal vesicle development. Proc. Natl. Acad. Sci. 91: 1074-8

Alsan, B. H. and Schultheiss, T. M. (2002). Regulation of avian cardiogenesis by Fgf8 signaling. Development 129: 1935-1943. 11934859

Alvares, L. E., et al. (2003). Intrinsic, Hox-dependent cues determine the fate of skeletal muscle precursors. Dev. Cell 5: 379-390. 12967558

Alvarez, Y., et al. (2003). Requirements for FGF3 and FGF10 during inner ear formation. Development 130: 6329-6338. 14623822

Ambrosetti, D. C., Basilico, C. and Dailey, L. (1997). Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding sites. Mol. Cell. Biol. 17(11): 6321-9.

Aoto, K., et al. (2002). Mouse GLI3 regulates Fgf8 expression and apoptosis in the developing neural tube, face, and limb bud. Dev. Bio. 251: 320-332. 12435361

Araújo, S. J., Cela, C. and Llimargas, M. (2007). Tramtrack regulates different morphogenetic events during Drosophila tracheal development. Development 134(20): 3665-76. PubMed citation: 17881489

Bachiller, D., et al. (2003). The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome. Development 130: 3567-3578. 12810603

Bei, M. and Maas, R. (1998). FGFs and BMP4 induce both Msx1-independent and Msx1-dependent signaling pathways in early tooth development. Development 125(21): 4325-4333.

Beiman, M., Shilo, B.-Z. and Volk, T. (1996). Heartless, a Drosophila FGF receptor homolog, is essential for cell migration and establishment of several mesodermal lineages. Genes Dev. 10: 2993-3002

Bellusci, S., et al. (1997). Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. Development 124(23): 4867-4878.

Bel-Vialar, S., Itasaki, N. and Krumlauf, R. (2002). Initiating Hox gene expression: in the early chick neural tube differential sensitivity to FGF and RA signaling subdivides the HoxB genes in two distinct groups. Development 129: 5103-5115. 12399303

Bertrand, N., Medevielle, G. and Pituello, F. (2000). FGF signalling controls the timing of Pax6 activation in the neural tube. Development 127: 4837-4843. 11044398

Bertrand, V., et al. (2003). Neural tissue in ascidian embryos is induced by FGF9/16/20, acting via a combination of maternal GATA and Ets transcription factors. Cell 115: 615-627. 14651852

Bhushan, A., et al. (2001). Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis. Development 128: 5109-5117. 11748146

Biesiada, E., Razandi, M., and Levin, E. R. (1997). Egr-1 activates basic fibroblast growth factor transcription. Mechanistic implications for astrocyte proliferation. J. Biol. Chem. 271(31): 18576-18581.

Boettger, T., Wittler, L. and Kessel, M. (1999). FGF8 functions in the specification of the right body side of the chick. Curr. Biol. 9(5): 277-80.

Bonnet, H., et al. (1996). Fibroblast growth factor-2 binds to the regulatory beta subunit of CK2 and directly stimulates CK2 activity toward nucleolin. J. Biol. Chem. 271(40): 24781-24787.

Brewster, R, Mullor, J. L. and Ruiz I Altaba, A. (2000). Gli2 functions in FGF signaling during antero-posterior patterning. Development 127: 4395-4405.

Buckland, R. A., et al. (1998). Antagonistic effects of FGF4 on BMP induction of apoptosis and chondrogenesis in the chick limb bud. Mech. Dev. 71(1-2): 143-150.

Burdine, R. D., et al. (1997). egl-17 encodes an invertebrate fibroblast growth factor family member required specifically for sex myoblast migration in Caenorhabditis elegans Proc. Natl. Acad. Sci. 94: 2433-37

Burdine, R., Branda, C. and Stern, M. (1998). EGL-17(FGF) expression coordinates the attraction of the migrating sex myoblasts with vulval induction in C. elegans. Development 125(6): 1083-1093.

Burdsal, C. A., Flannery, M. L. and Pedersen, R. A. (1998). FGF-2 alters the fate of mouse epiblast from ectoderm to mesoderm in vitro. Dev. Biol. 198(2): 231-244.

Bushdid, P. B., et al. (2001). NF-kappaB mediates fgf signal regulation of msx-1 expression. Dev. Bio. 237: 107-115. 11518509

Carballada, R., Yasuo, H. and Lemaire, P. (2001). Phosphatidylinositol-3 kinase acts in parallel to the ERK MAP kinase in the FGF pathway during Xenopus mesoderm induction. Development 128: 35-44

Caruccio, N. C., et al. (1999). Constitutive activation of sonic hedgehog signaling in the chicken mutant talpid(2): Shh-independent outgrowth and polarizing activity. Dev. Biol. 212(1): 137-149.

Casey, E. S., et al. (1998). The T-box transcription factor Brachyury regulates expression of eFGF through binding to a non-palindromic response element. Development 125(19): 3887-3894

Cepko, C. L. (1999). The roles of intrinsic and extrinsic cues and bHLH genes in the determination of retinal cell fates. Curr. Opin. Neurobiol. 9: 37-46.

Chai, N., et al. (1998). FGF is an essential regulator of the fifth cell division in preimplantation mouse embryos. Dev. Biol. 198(1): 105-115.

Chambers, D., et al. (2000a). Differential display of genes expressed at the midbrain - hindbrain junction identifies sprouty2: an FGF8-inducible member of a family of intracellular FGF antagonists. Mol. Cell. Neurosci. 15(1): 22-35.

Chambers, D. and Mason, I. (2000b). Expression of sprouty2 during early development of the chick embryo is coincident with known sites of FGF signalling. Mech. Dev. 91(1-2): 361-4.

Chan, D. C., Wynshaw-Boris, A. and Leder, P. (1995). Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of fgf-4 and shh in the limb bud. Development 121(10): 3151-62.

Chandran, S., et al. (2003). FGF-dependent generation of oligodendrocytes by a hedgehog-independent pathway. Development 130: 6599-6609. 14660548

Chang, W., et al. (2004). The development of semicircular canals in the inner ear: role of FGFs in sensory cristae. Development 131: 4201-4211. 15280215

Chaudhary, A., et al. (2000). Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338. Curr. Biol. 10: 551-554.

Chen, Y., Li, X., Eswarakumar, V. P., Seger, R. and Lonai, P. (2000). Fibroblast growth factor (FGF) signaling through PI 3-kinase and Akt/PKB is required for embryoid body differentiation. Oncogene 19: 3750-3756. 10949929

Cheon, H. G., et al. (1994). High-affinity binding sites for related fibroblast growth factor ligands reside within different receptor immunoglobulin-like domains. Proc Natl Acad Sci 91: 989-93

Chi, C. L., et al. (2003). The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum. Development 130: 2633-2644. 12736208

Chihara, T., et al. (2003). Rac promotes epithelial cell rearrangement during tracheal tubulogenesis in Drosophila. Development 130: 1419-1428. 12588856

Christen, B. and Slack, J. M. (1997). FGF-8 is associated with anteroposterior patterning and limb regeneration in Xenopus. Dev. Biol. 192(2): 455-466.

Ciccolini, F. and Svendsen, C. N. (1998). Fibroblast growth factor 2 (FGF-2) promotes acquisition of epidermal growth factor (EGF) responsiveness in mouse striatal precursor cells: identification of neural precursors responding to both EGF and FGF-2. J. Neurosci. 18(19): 7869-80.

Colvin, J. S., et al. (2001a). Male-to-female sex reversal in mice lacking Fibroblast growth factor 9. Cell 104: 875-889. 11290325

Colvin, J. S., et al. (2001b). Lung hypoplasia and neonatal death in Fgf9-null mice identify this gene as an essential regulator of lung mesenchyme. Development 128: 2095-2106. 11493531

Crump, J. G., et al. (2004). An essential role for Fgfs in endodermal pouch formation influences later craniofacial skeletal patterning. Development 131: 5703-5716. 15509770

Culp, P. A. and Musci, T. J. (1998). Translational activation and cytoplasmic polyadenylation of FGF Receptor-1 are independently regulated during Xenopus cocyte maturation. Dev. Biol. 193(1): 63-76

Dasen, J. S., et al. (2001). Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 15: 3193-3207. 11731482

David, N. B., et al. (2002). Requirement for endoderm and FGF3 in ventral head skeleton formation. Development 129: 4457-4468. 12223404

Dixon, S. J., Alexander, M., Fernandes, R., Ricker, N. and Roy, P. J. (2006). FGF negatively regulates muscle membrane extension in Caenorhabditis elegans. Development 133(7):1263-75. 16495308

Dealy, C. N., et al. (1997). FGF-stimulated outgrowth and proliferation of limb mesoderm is dependent on Syndecan-3. Dev. Biol. 184: 343-350.

Delbridge, G. J. and Khachigian, L. M. (1997). FGF-1-induced platelet-derived growth factor-A chain gene expression in endothelial cells involves transcriptional activation by early growth response factor-1. Circ. Res. 81(2): 282-288.

Desire, L., et al. (1998). Suppression of fibroblast growth factor 2 expression by antisense oligonucleotides inhibits embryonic chick neural retina cell differentiation and survival in vivo. Dev. Dyn. 212(1): 63-74.

Diez del Corral, R. D., Breitkreuz, D. N. and Storey, K. G. (2002). Onset of neuronal differentiation is regulated by paraxial mesoderm and requires attenuation of FGF signaling. Development 129: 1681-1691. 11923204

Diez del Corral, R. D., et al. (2003). Opposing FGF and retinoid pathways control ventral neural pattern, neuronal differentiation, and segmentation during body axis extension. Neuron 40: 65-79. 14527434

Donohue, P. J., et al. (1997). Fibroblast growth factor-1 induction of delayed-early mRNA expression in NIH 3T3 cells is prolonged by heparin addition. Exp. Cell Res. 234(1): 139-146.

Dorfman, R., Shilo, B. Z. and Volk, T. (2002). Stripe provides cues synergizing with Branchless to direct tracheal cell migration. Dev. Bio. 252: 119-126. 12453464

Draper, B. W., Stock, D. W. and Kimmel, K. B. (2003). Zebrafish fgf24 functions with fgf8 to promote posterior mesodermal development. Development 130: 4639-4654. 12925590

Eblaghie, M. C., et al. (2003). Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos. Curr. Biol. 13: 1009-1018. 12814546

Edom-Vovard, F., Bonnin, M.-A. and Duprez, D. (2001). Misexpression of Fgf-4 in the chick limb inhibits myogenesis by down-regulating Frek expression. Dev. Biol. 233: 56-71. 11319857

Edom-Vovard, F., et al. (2002). Fgf4 positively regulates scleraxis and tenascin expression in chick limb tendons. Dev. Biol. 247: 351-366. 12086472

Englund, C., et al. (1999). adrift, a novel bnl-induced Drosophila gene, required for tracheal pathfinding into the CNS. Development 126: 1505-1514.

Englund, C., et al. (2002). Attractive and repulsive functions of Slit are mediated by different receptors in the Drosophila trachea. Development 129: 4941-4951. 12397103

Faloon, P., et al. 2000). Basic fibroblast growth factor positively regulates hematopoietic development. Development 127: 1931-1941

Firnberg, N. and Neubuser, A. (2002). FGF signaling regulates expression of Tbx2, Erm, Pea3, and Pax3 in the early nasal region. Dev. Bio. 247: 237-250. 12086464

Fisher, M. E., Isaacs, H. V. and Pownall, M. E. (2002). eFGF is required for activation of XmyoD expression in the myogenic cell lineage of Xenopus laevis. Development 129: 1307-1315. 11880340

Fischer, S., Draper, B. W. and Neumann, C. J. (2003). The zebrafish fgf24 mutant identifies an additional level of Fgf signaling involved in vertebrate forelimb initiation. Development 130: 3515-3524. 12810598

Fleming, T. C., Wolf, F. W. and Garriga, G. (2005). Sensitized genetic backgrounds reveal a role for C. elegans FGF EGL-17 as a repellent for migrating CAN neurons. Development 132(21): 4857-67. 16207764

Floss, T., Arnold, H. H. and Braun, T. (1997). A role for FGF-6 in skeletal muscle regeneration. Genes Dev. 11(16): 2040-2051.

Fraidenraich, D., Lang, R. and Basilico, C. (1998). Distinct regulatory elements govern Fgf4 gene expression in the mouse blastocyst, myotomes, and developing limb. Dev. Biol. 204(1): 197-209.

Fraidenraich, D., et al. (2000). Activation of Fgf4 gene expression in the myotomes is regulated by myogenic bHLH factors and by sonic hedgehog. Dev. Bio. 225: 392-406.

Frank, D. U., et al. (2002). An Fgf8 mouse mutant phenocopies human 22q11 deletion syndrome. Development 129: 4591-4603. 12223415

Furthauer, M., Thisse, C. and Thisse, B. (1997). A role for FGF-8 in the dorsoventral patterning of the zebrafish gastrula. Development 124(21): 4253-4264.

Fürthauer, M., et al. (2004). Fgf signalling controls the dorsoventral patterning of the zebrafish embryo. Development 131: 2853-2864. 15151985

Gabay, L., Lowell, S., Rubin, L. L. and Anderson, D. J. (2003). Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro. Neuron 40: 485-499. 14642274

Garda, A. L., Echevarria, D., and Martinez, S. (2001). Neuroepithelial co-expression of Gbx2 and Otx2 precedes Fgf8 expression in the isthmic organizer. Mech. Dev. 101: 111-118. 11231064

Garel, S., Huffman, K. J. and Rubenstein, J. L. R. (2003). Molecular regionalization of the neocortex is disrupted in Fgf8 hypomorphic mutants, Development 130: 1903-1914. 12642494

Gemel, J., Jacobsen, C. and MacArthur, C. A. (1999). Fibroblast growth factor-8 expression is regulated by intronic engrailed and Pbx1-binding sites. J. Biol. Chem. 274(9): 6020-6.

Ghabrial, A. S. and Krasnow, M. A. (2006). Social interactions among epithelial cells during tracheal branching morphogenesis. Nature 441(7094): 746-9. 16760977

Gisselbrecht, S., et al. (1996). heartless encodes a fibroblast growth factor receptor (DFR1/DFGF-R2) involved in the directional migration of early mesodermal cells in the Drosophila embryo. Genes Dev. 10: 3003-3017

Glienke, J., et al. (2000). Human SPRY2 inhibits FGF2 signalling by a secreted factor. Mech. Dev. 91-99

Gomm, J. J., et al. (1997). A paracrine role for myoepithelial cell-derived FGF2 in the normal human breast. Exp. Cell Res. 234(1): 165-173.

Govindarajan, V., et al. (2000). Endogenous and ectopic gland induction by FGF-10. Dev. Bio. 225: 188-200.

Grapin-Botton, A., et al. (1999). Patterning signals acting in the spinal cord override the organizing activity of the isthmus Mec. Dev. 84 (1-2): 41-53.

Grigoriou, M., et al. (1998). Expression and regulation of Lhx6 and Lhx7, a novel subfamily of LIM homeodomain encoding genes, suggests a role in mammalian head development. Development 125: 2063-2074.

Grisaru, S., et al. (2001). Glypican-3 modulates BMP- and FGF-mediated effects during renal branching morphogenesis. Dev. Bio. 231: 31-46. 11322381

Gritti, A., et al. (1999). Epidermal and fibroblast growth factors behave as mitogenic regulators for a single multipotent stem cell-like population from the subventricular region of the adult mouse forebrain. J. Neurosci. 19(9): 3287-97.

Guillemin, K. et al. (1996). The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal brancing of the tracheal system. Development 122: 1353-62

Guillonneau, X., et al. (1998). Fibroblast growth factor (FGF) soluble receptor 1 acts as a natural inhibitor of FGF2 neurotrophic activity during retinal degeneration. Mol. Biol. Cell 9(10): 2785-802.

Guo, L., Yu, Q. C. and Fuchs, E. (1993). Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice. EMBO J 12: 973-86

Guo, S., et al. (1999). Development of noradrenergic neurons in the zebrafish hindbrain requires BMP, FGF8, and the homeodomain protein Soulless/Phox2a. Neuron 24: 555-566.

Harada, H., et al. (2002). FGF10 maintains stem cell compartment in developing mouse incisors. Development 129: 1533-1541. 11880361

Hardcastle, Z., Chalmers, A. D. and Papalopulu, N. (2000). FGF-8 stimulates neuronal differentiation through FGFR-4a and interferes with mesoderm induction in Xenopus embryos. Curr. Biol. 10: 1511-1514. 11114518

Haremaki, T., et al. (2003). Integration of multiple signal transducing pathways on Fgf response elements of the Xenopus caudal homologue Xcad3. Development 130: 4907-4917. 12930781

Hashimoto, K., et al. (1999). Distinct signaling molecules control Hoxa-11 and Hoxa-13 expression in the muscle precursor and mesenchyme of the chick limb bud. Development 126(12): 2771-2783.

Hatch, E. P., Noyes, C. A., Wang, X., Wright, T. J. and Mansour, S. L. (2007). Fgf3 is required for dorsal patterning and morphogenesis of the inner ear epithelium. Development 134(20): 3615-25. Medline abstract: 17855431

Hemphälä, et al. (2003). Grainy head controls apical membrane growth and tube elongation in response to Branchless/FGF signalling. Development 130: 249-258. 12466193

Henig, C., Elias, S. and Frank, D. (1998). A POU protein regulates mesodermal competence to FGF in Xenopus. Mech. Dev. 71(1-2): 131-142.

Henrique, D., et al. (1997). cash4, a novel achaete-scute homolog induced by Hensen's node during generation of the posterior nervous system. Genes Dev. 11:603-615.

Herzog, W., et al. (2004). Fgf3 signaling from the ventral diencephalon is required for early specification and subsequent survival of the zebrafish adenohypophysis. Development 131: 3681-3692. 15229178

Heymann, et al. (1996). Regulation and function of SF/HGF during migration of limb muscle precursor cells in chickens. Dev. Biol. 180: 566-578

Hidalgo-Sanchez, M., et al. (1999). Comparative analysis of Otx2, Gbx2, Pax2, Fgf8 and Wnt1 gene expressions during the formation of the chick midbrain/hindbrain domain. Mech. Dev. 81(1-2): 175-8.

Holowacz, T. and Sokol, S. (1999). FGF is required for posterior neural patterning but not for neural induction. Dev. Biol. 205(2): 296-308.

Hongo, I., Kengaku, M. and Okamoto, H. (1999). FGF signaling and the anterior neural induction in Xenopus. Dev. Biol. 216(2): 561-81.

Hosono, C., Takaira, K., Matsuda, R. and Saigo, K. (2003). Functional subdivision of trunk visceral mesoderm parasegments in Drosophila is required for gut and trachea development. Development 130: 439-449. 12490551

Hou, S., et al. (2007). The secreted serine protease xHtrA1 stimulates long-range FGF signaling in the early Xenopus embryo. Dev. Cell 13(2): 226-41. PubMed citation: 17681134

Hu, N. and Castelli-Gair, J. (1999). Study of the posterior spiracles of Drosophila as a model to understand the genetic and cellular mechanisms controlling morphogenesis. Dev. Biol. 214(1): 197-210.

Huang, L., Pu, Y., Alam, S., Birch, L. and Prins, G. S. (2005). The role of Fgf10 signaling in branching morphogenesis and gene expression of the rat prostate gland: lobe-specific suppression by neonatal estrogens. Dev. Biol. 278(2): 396-414. 15680359

Huang, R., et al. (2003). Ventral axial organs regulate expression of myotomal Fgf-8 that influences rib development. Dev. Bio. 255: 30-47. 12618132

Hyer, J., Mima, T. and Mikawa, T. (1998). FGF1 patterns the optic vesicle by directing the placement of the neural retina domain. Development 125(5): 869-877.

Imai, K. S., Satoh, N. and Satou, Y. (2002a). Early embryonic expression of FGF4/6/9 gene and its role in the induction of mesenchyme and notochord in Ciona savignyi embryos. Development 129: 1729-1738. 11923208

Imai, K. S., Satoh, N. and Satou, Y. (2002b). An essential role of a FoxD gene in notochord induction in Ciona embryos. Development 129: 3441-3453. 12091314

Imai, K. S., Satoh, N. and Satou, Y. (2003). A Twist-like bHLH gene is a downstream factor of an endogenous FGF and determines mesenchymal fate in the ascidian embryos. Development 130: 4461-4472. 12900461

Irving, C. and Mason, M. (2000). Signalling by FGF8 from the isthmus patterns anterior hindbrain and establishes the anterior limit of Hox gene expression. Development 127: 177-186.

Irving, C., et al. (2002). Establishing the trochlear motor axon trajectory: role of the isthmic organiser and Fgf8. Development 129: 5389-5398. 12403710

Isaacs, H. V., Pownall, M. E. and Slack, J. M. (1994). eFGF regulates Xbra expression during Xenopus gastrulation. EMBO J. 13(19): 4469-4481.

Iseki, S., et al. (1997). Fgfr2 and osteopontin domains in the developing skull vault are mutually exclusive and can be altered by locally applied FGF2. Development 124(17): 3375-3384.

Ishibashi, M. and McMahon, A. P. (2002). A sonic hedgehog-dependent signaling relay regulates growth of diencephalic and mesencephalic primordia in the early mouse embryo. Development 129: 4807-4819. 12361972

Izvolsky, K. I., et al. (2003). Heparan sulfate-FGF10 interactions during lung morphogenesis. Dev. Biol. 258: 185-200. 12781692

Jackman, W. R., Draper, B. W. and Stock, D. W. (2004). Fgf signaling is required for zebrafish tooth development. Dev. Biol. 274: 139-157. 15355794

Jarecki, J. Johnson, E. and Krasnow, M. A. (1999). Oxygen regulation of airway branching in Drosophila Is mediated by Branchless FGF. Cell 99: 211-220.

Jiang, F., Frederick, T. J. and Wood, T. L. (2001). IGF-I synergizes with FGF-2 to stimulate oligodendrocyte progenitor entry into the cell cycle. Dev. Bio. 232: 414-423

Johnson, D. E. and Williams, L. T. (1993). Structure and functional diversity in the FGF receptor multigene family. Adv. Cancer Res. 60: 1-41

Jonca, F., et al. (1997). Cell release of bioactive fibroblast growth factor 2 by exon 6-encoded sequence of vascular endothelial growth factor. J. Biol. Chem. 272(39): 24203-24209.

Jung, H. S., et al. (1998). Local inhibitory action of BMPs and their relationships with activators in feather formation: implications for periodic patterning. Dev. Biol. 196(1): 11-23.

Jung, H. S., Oropeza, V. and Thesleff, I. (1999). Shh, bmp-2, bmp-4 and fgf-8 are associated with initiation and patterning of mouse tongue papillae. Mech. Dev. 81(1-2): 179-82.

Kamikura, D. M. and Cooper, J. A. (2003). Lipoprotein receptors and a Disabled family cytoplasmic adaptor protein regulate EGL-17/FGF export in C. elegans. Genes Dev. 17: 2798-2811. 14630941

Kamimura, K., et al. (2006). Specific and flexible roles of heparan sulfate modifications in Drosophila FGF signaling. J. Cell. Biol. 174(6): 773-8. Medline abstract: 16966419

Kawakami, Y., et al. (2001). WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo. Cell 104: 891-900. 11290326

Kengaku, M. and Okamoto, H. (1995). bFGF as a possible morphogen for the anteroposterior axis of the central nervous system in Xenopus. Development 121: 3121-3130

Kettunen, P. and Thesleff, I. (1998). Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis. Dev. Dyn. 211(3): 256-268.

Kim, G. J., Yamada, A. and Nishida, H. (2000). An FGF signal from endoderm and localized factors in the posterior-vegetal egg cytoplasm pattern the mesodermal tissues in the ascidian embryo. Development 127: 2853-2862.

Kondoh, K., Kobayashi, K. and Nishida, H. (2003). Suppression of macho-1-directed muscle fate by FGF and BMP is required for formation of posterior endoderm in ascidian embryos. Development 130: 3205-3216. 12783791

Koshida, S., et al. (1998). Initial anteroposterior pattern of the zebrafish central nervous system is determined by differential competence of the epiblast. Development 125(10): 1957-1966.

Koshida, S., et al. (2002). Inhibition of BMP activity by the FGF signal promotes posterior neural development in zebrafish. Dev. Biol. 244: 9-20. 11900455

Kouhara, H., et al. (1997). A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell 89 (5): 693-702.

Kudoh, T., Wilson, S. W. and Dawid, I. B. (2002). Distinct roles for Fgf, Wnt and retinoic acid in posteriorizing the neural ectoderm. Development 129: 4335-4346. 12183385

Kudoh, T., et al. (2004). Combinatorial Fgf and Bmp signalling patterns the gastrula ectoderm into prospective neural and epidermal domains. Development 131: 3581-3592. 15262889

Kuo, W. L., Chung, K. C. and Rosner, M. R. (1997). Differentiation of central nervous system neuronal cells by fibroblast-derived growth factor requires at least two signaling pathways: roles for Ras and Src. Mol. Cell. Biol. 17: 4633-4643.

Kuzis, K., et al. (1995). Developmental time course of acidic and basic fibroblast growth factors' expression in distinct cellular populations of the rat central nervous system. J Comp Neurol 358: 142-153

Kwak, S.-K., et al. (2002). An expanded domain of fgf3 expression in the hindbrain of zebrafish valentino mutants results in mis-patterning of the otic vesicle. Development 129: 5279-5287. 12399318

LaBonne, C. and Whitman, M. (1997). Localization of MAP kinase activity in early Xenopus embryos: implications for endogenous FGF signaling. Dev. Biol. 183 (1): 9-20.

Ladd, A. N., Yatskievych, T. A., Antin, P. B. (1998). Regulation of avian cardiac myogenesis by Activin/TGFbeta and bone morphogenetic proteins. Dev. Biol. 204(2): 407-19.

Lamb. T. M., and Harland, R. M. (1995). Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern. Development 121: 3627-3636

Larrain, J., et al. (1997). Expression of perlecan, a proteoglycan that binds myogenic inhibitory basic fibroblast growth factor, is down regulated during skeletal muscle differentiation. Exp. Cell Res. 234(2): 405-412.

Latinkic. B. V., et al. (1997). The Xenopus Brachyury promoter is activated by FGF and low concentrations of activin and suppressed by high concentrations of activin and by paired-type homeodomain proteins. Genes Dev. 11(23): 3265-3276. .

Lee, S. M. K., et al. (1997). Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain. Development 124: 959-969.

Leenders, W. P., et al. (1997). Synergism between temporally distinct growth factors: bFGF, insulin and lens cell differentiation. Mech. Dev. 67(2): 193-201.

LeSueur, J. A., et al. (2002). Smad10 is required for formation of the frog nervous system. Dev. Cell 2: 771-783. 12062089

Li, J. Y. H., Lao, Z. and Joyner, A. L. (2002). Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer. Neuron 36: 31-43. 12367504

Li, L., et al. (2004). Distinct GATA6- and laminin-dependent mechanisms regulate endodermal and ectodermal embryonic stem cell fates. Development 131: 5277-5286. 15456727

Li, S. and Muneoka, K. (1999). Cell migration and chick limb development: chemotactic action of FGF-4 and the AER. Dev. Biol. 211(2): 335-47.

Li, X., Chen, Y., Scheele, S., Arman, E., Haffner-Krausz, R., Ekblom, P. and Lonai, P. (2001). FGF signaling and basement membrane assembly are connected during epithelial morphogenesis of the embryoid body. J. Cell Biol. 153: 811-822. 11352941

Lillien, L. and Raphael, H. (2000). BMP and FGF regulate the development of EGF-responsive neural progenitor cells. Development 127: 4993-5005. 11044412

Lin, X., et al. (1999). Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development. Development 126: 3715-3723.

Litsiou, A. Hanson, S. and Streit, A. (2005). A balance of FGF, BMP and WNT signalling positions the future placode territory in the head. Development 132: 4051-4062. 16093325

Liu, A., Losos, K. and Joyner, A. L. (1999). FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate. Development 126: 4827-4838.

Liu, A. and Joyner, A. L. (2001). EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region. Development 128: 181-191. 11124114

Liu, A., et al. (2003). FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors. Development 130: 6175-6185. 14602678

Liu, C., et al. (2003). A role for the mesenchymal T-box gene Brachyury in AER formation during limb development. Development 130: 1327-1337. 12588849

Liu, J. P., Laufer, E. and Jessell, T. M. (2001). Assigning the positional identity of spinal motor neurons: Rostrocaudal patterning of Hox-c Expression by FGFs, Gdf11, and retinoids. Neuron 32: 997-1012. 11754833

Liu, Y., et al. (2002). growth arrest specific gene 1 acts as a region-specific mediator of the Fgf10/Fgf8 regulatory loop in the limb. Development 129: 5289-5300. 12399319

Liu, Z., et al. (2002). Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. Genes Dev. 16: 859-869. 11937493

Lobjois, V., et al. (2004). Specific regulation of cyclins D1 and D2 by FGF and Shh signaling coordinates cell cycle progression, patterning, and differentiation during early steps of spinal cord development. Dev. Biol. 273: 195-209. 15328007

Logan, C., et al. (1997). The role of Engrailed in establishing the dorsoventral axis of the chick limb. Development 124 (12): 2317-2324.

Lombardo, A. and Slack, J. M. (1998). Postgastrulation effects of fibroblast growth factor on Xenopus development. Dev. Dyn. 212(1): 75-85.

Londin, E. R., Niemiec, J. and Sirotkin, H. I. (2005). Chordin, FGF signaling, and mesodermal factors cooperate in zebrafish neural induction. Dev. Biol. 279(1): 1-19. 15708554

Lovicu, F. J. McAvoy, J. W. (2001). FGF-induced lens cell proliferation and differentiation is dependent on MAPK (ERK1/2) signaling. Development 128: 5075-5084. 11748143

Lu, H. C., et al. (2001). Evidence for a role of protein kinase C in FGF signal transduction in the developing chick limb bud. Development 128: 2451-2460. 11493562

Macatee, T. L., et al. (2003). Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development. Development 130: 6361-6374. 14623825

Mailleux, A. A., et al. (2001). Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis Mech. Dev. 102: 81-94. 11287183

Mailleux, A. A., et al. (2005). Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage. Development 132(9): 2157-66. 15800000

Makarenkova, H., et al. (1997). Fibroblast growth factor 4 directs gap junction expression in the mesenchyme of the vertebrate limb bud. J. Cell Biol. 138(5): 1125-1137.

Makarenkova, H. P., et al. (2000). FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development. Development 127(12): 2563-72.

Mandler, M. and Neub¸ser, A. (2004). FGF signaling is required for initiation of feather placode development. Development 131: 3333-3343. 15201222

Marics, I., et al. (2002). FGFR4 signaling is a necessary step in limb muscle differentiation. Development 129: 4559-4569. 12223412

Marín, F. and Charnay, P. (2000). Hindbrain patterning: FGFs regulate Krox20 and mafB/kr expression in the otic/preotic region. Development 127: 4925-4935. 11044406

Maroon, H., et al. (2002). Fgf3 and Fgf8 are required together for formation of the otic placode and vesicle. Development 129: 2099-2108. 11959820

Martinez, S., et al. (1999). FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression. Development 126(6): 1189-1200.

Martinez-Barbera, J. P., et al. (2001). Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2. Development 128: 4789-4800. 11731459

Mason, I. J., et al. (1994). FGF-7 (keratinocyte growth factor) expression during mouse development suggests roles in myogenesis, forebrain regionalisation and epithelial-mesenchymal interactions. Mech Dev 45: 15-30

Mathieu, J., et al. (2004). Nodal and Fgf pathways interact through a positive regulatory loop and synergize to maintain mesodermal cell populations. Development 131: 629-641. 14711879

Maves, L., Jackman, W. and Kimmel, C. B. (2002). FGF3 and FGF8 mediate a rhombomere 4 signaling activity in the zebrafish hindbrain. Development 129: 3825-3837. 12135921

Mayor, R., Guerrero, N. and MartÌnez, C. (1997). Role of FGF and noggin in neural crest induction. Dev. Biol. 189(1): 1-12

McFarlane, S., McNeill, L. and Holt, C. E. (1995). FGF signaling and target recognition in the developing Xenopus visual system. Neuron 15: 1017-1028

McGrew, L. L., Hoppler, S. and Moon, R. T. (1997). Wnt and FGF pathways cooperatively pattern anteroposterior neural ectoderm in Xenopus. Mech. Dev. 69(1-2): 105-114

McWhirter, J. R., et al. (1997). A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1. Development 124(17): 3221-3232.

Meiners, S., et al. (1993). Regulation of astrocytic tenascin by basic fibroblast growth factor. Dev. Biol. 160 (2): 480-493.

Mercader, N., et al. (2000). Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes. Development 127: 3961-3970. 10952894

Min, H., et al. (1998). Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless. Genes Dev. 12(20): 3156-61.

Miralles, F., et al. (1999). Signaling through fibroblast growth factor receptor 2b plays a key role in the development of the exocrine pancreas. Proc. Natl. Acad. Sci. 96(11):6267-72. 99272682

Miyanaga, Y., Shiurba, R. and Asashima, M. (1999). Blood cell induction in Xenopus animal cap explants: effects of fibroblast growth factor, bone morphogenetic proteins, and activin. Dev. Genes Evol. 209(2): 69-76.

Moftah, M. Z., et al. (2002). Ectodermal FGFs induce perinodular inhibition of limb chondrogenesis in vitro and in vivo via FGF receptor 2. Dev. Bio. 249: 270-282. 12221006

Monsoro-Burq, A.-H., Fletcher, R. B. and Harland, R. M. (2003). Neural crest induction by paraxial mesoderm in Xenopus embryos requires FGF signals. Development 130: 3111-3124. 12783784

Montero, J. A., et al. (2001). Role of FGFs in the control of programmed cell death during limb development. Development 128: 2075-2084. 11493529

Moon, A. M., Boulet, A. M. Capecchi, M. R. (2000). Normal limb development in conditional mutants of Fgf4. Development 127: 989-996. 10662638

Moore, K. B., et al. (2004). Morphogenetic movements underlying eye field formation require interactions between the FGF and ephrinB1 signaling pathways. Dev. Cell 6: 55-67. 14723847

Moore, R., et al. (2002). Blocking endogenous FGF-2 activity prevents cranial osteogenesis. Dev. Biol. 243: 99-114. 11846480

Morgan, E. A., et al. (2003). Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia. Development 130: 3095-3109. 12783783

Morrow, T., Song, M.-R. and Ghosh, A. (2001). Sequential specification of neurons and glia by developmentally regulated extracellular factors. Development 128: 3585-3594. 11566862

Muhr, J., et al. (1999). Convergent inductive signals specify midbrain, hindbrain, and spinal cord identity in gastrula stage chick embryos. Neuron 23: 689-702.

Munoz-Sanjuan, I., et al. (1999). Expression of chicken fibroblast growth factor homologous factor (FHF)-1 and of differentially spliced isoforms of FHF-2 during development and involvement of FHF-2 in chicken limb development. Development 126(2): 409-421.

Mustonen, T., et al. (2002). Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth. Dev. Bio. 248: 281-293. 12167404

Continued: Branchless References part 2/2


branchless: Biological Overview | Evolutionary Homologs | Regulation | Developmental Biology | Effects of Mutation

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