death executioner Bcl-2 homologue

EVOLUTIONARY HOMOLOGS
Table of Contents

page 1

Bcl-2 and Bcl-x_L promote cell survival
Bcl-x_L deamidation regulates the response to DNA damage
Proapoptotic Bcl-2 family members
Interactions among pro- and anti-apoptotic Bcl-2 family members

page 2

Domain structure and function of pro-apoptotic Bcl-2 family members
Bcl-2 family members as regulators of the cell death hierarchy: Bcl-2 interacts with Apaf-1
Bcl-2 family members are targets of caspases
Bcl-2 family members: transcriptional regulation
Signaling upstream of Bcl-2 family members

page 3

Bcl-2 family members as regulators of the cell death hierarchy: Bcl-2 proteins as
      ion channels and regulators of mitochondrial membrane permiability
Signaling downstream of Bcl-2 family members
Interaction between mutant superoxide dismutase and Bcl-2

page 4

Bcl-2 family members as regulators of the cell death hierarchy: ced-9 in C. elegans
Bcl-2 and inflamation
Bcl-2, development, cell growth and entry into the cell cycle
bcl-2 is required for appropriate development of retinal vasculature as well as its neovascularization during oxygen-induced ischemic retinopathy

Home page: The Interactive Fly © 1995, 1996 Thomas B. Brody, Ph.D.

The Interactive Fly resides on the
Society for Developmental Biology's Web server.