ovarian tumor

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Bae, E., et al. (1994). Molecular characterization of ovarian tumors in Drosophila. Mech. Dev. 47(2): 151-164.

Comer, A. R., Searles, L. L. and Kalfayan, L. J. (1992). Identification of a genomic DNA fragment containing the Drosophila melanogaster ovarian tumor gene (otu) and localization of regions governing its expression. Gene 118(2): 171-179.

Geyer, P. K., et al. (1993). Genetic and molecular characterization of P element-induced mutations reveals that the Drosophila ovarian tumor gene has maternal activity and a variable null phenotype. Genetics 133(2): 265-278.

Glenn, L. E. and Searles, L. L. (2001). Distinct domains mediate the early and late functions of the Drosophila ovarian tumor proteins. Mech. Dev. 102: 181-191. 11287191

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Goodrich, J. S., Clouse, K. N. and Schüpbach, T. (2004). Hrb27C, Sqd and Otu cooperatively regulate gurken RNA localization and mediate nurse cell chromosome dispersion in Drosophila oogenesis. Development 131: 1949-1958. 15056611

Hammond, L. E., Rudner, D. Z., Kanaar, R. and Rio, D. C. (1997). Mutations in the hrp48 gene, which encodes a Drosophila heterogeneous nuclear ribonucleoprotein particle protein, cause lethality and developmental defects and affect P-element third-intron splicing in vivo. Mol. Cell. Biol. 17: 7260-7267. 9372958

Heino, T. I., et al. (1995). Polytene chromosomes show normal gene activity but some mRNAs are abnormally accumulated in the pseudonurse cell nuclei of Drosophila melanogaster otu mutants. Chromosoma 104(1): 44-55.

Hinson, S. and Nagoshi, R. N. (1999a). Regulatory and functional interactions between the somatic sex regulatory gene transformer and the germline genes ovo and ovarian tumor. Development 126: 861-871

Hinson, S., Pettus, J. and Nagoshi. R. N. (1999). Regulatory and functional interactions between ovarian tumor and ovo during Drosophila oogenesis. Mech. Dev. 88: 3-14

Jackson, S. M. and Berg, C. A. (1999). Soma-to-germline interactions during Drosophila oogenesis are influenced by dose-sensitive interactions between cut and the genes cappuccino, ovarian tumor and agnostic. Genetics, Vol. 153: 289-303.

Keyes, L. N. and Spradling, A. C. (1997). The Drosophila gene fs(2)cup interacts with otu to define a cytoplasmic pathway required for the structure and function of germ-line chromosomes. Development 124: 1419-1431.

Lu, J., Andrews, J., Pauli, D. and Oliver, B. (1998). Drosophila OVO zinc-finger protein regulates ovo and ovarian tumor target promoters. Dev. Genes Evol. 208(4): 213-22.

Lu, J. and Oliver, B. (2001). Drosophila OVO regulates ovarian tumor transcription by binding unusually near the transcription start site. Development 128: 1671-1686. 11290304

Nagoshi, R. N., et al. (1995). The somatic sex determines the requirement for ovarian tumor gene activity in the proliferation of the Drosophila germline. Development 121(2): 579-587.

Norvell, A., Kelley, R. L., Wehr, K. and Schupbach, T. (1999). Specific isoforms of squid, a Drosophila hnRNP, perform distinct roles in Gurken localization during oogenesis. Genes Dev. 13: 864-876. 10197986

Pauli, D., Oliver, B., and Mahowald, A. P. (1993). The role of the ovarian tumor locus in Drosophila melanogaster germ line sex determination. Development 119(1): 123-134.

Rodesch, C., et al. (1995). Developmental analysis of the ovarian tumor gene during Drosophila oogenesis. Genetics 141(1): 191-202.

Rodesch, C., Pettus, J. and Nagoshi, R. N. (1997). The Drosophila ovarian tumor gene is required for the organization of actin filaments during multiple stages in oogenesis. Dev. Biol. 190(2): 153-164.

Sass, G. L., et al. (1993). Structure and expression of hybrid dysgenesis-induced alleles of the ovarian tumor (otu) gene in Drosophila melanogaster. Genetics 133(2): 253-263.

Sass, G. L., Comer, A. R. and Searles, L. L. (1995). The ovarian tumor protein isoforms of Drosophila melanogaster exhibit differences in function, expression, and localization. Dev. Biol. 167(1): 201-212.

Siebel, C. W., Kanaar, R. and Rio, D. C. (1994). Regulation of tissue-specific P-element pre-mRNA splicing requires the RNA-binding protein PSI. Genes Dev. 8: 1713-1725. 7958851

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Staab, S. and Steinmann-Zwicky, M. (1996). Female germ cells of Drosophila require zygotic ovo and otu product for survival in larvae and pupae respectively. Mech. Dev. 54: 205-210.

Steinhauer, W. R., Walsh, R. C. and Kalfayan, L. J. (1989). Sequence and structure of the Drosophila melanogaster ovarian tumor gene and generation of an antibody specific for the ovarian tumor protein. Mol. Cell Biol. 9(12): 5726-5732.

Steinhauer, W. R. and Kalfayan, L. J. (1992). A specific ovarian tumor protein isoform is required for efficient differentiation of germ cells in Drosophila oogenesis. Genes Dev. 6(2): 233-243.

Storto, P. D. and King, R. C. (1988). Multiplicity of functions for the otu gene products during Drosophila oogenesis. Dev. Genet. 9(2): 91-120

Tirronen, M., et al. (1993). Analyses of the Drosophila quit, ovarian tumor and shut down mutants in oocyte differentiation using in situ hybridisation. Mech. Dev. 40(1-2):113-126.

Tirronen, M., et al. (1995). Two otu transcripts are selectively localised in Drosophila oogenesis by a mechanism that requires a function of the otu protein. Mech. Dev. 52(1): 65-75.

Van Buskirk, C. V. and Schüpbach, T. (2002). half pint regulates alternative splice site selection in Drosophila. Developmental Cell 2: 343-353. 11879639

date revised: 25 July 2002 

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