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| Past SDB Meetings Page | |
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SDB 60th Annual Meeting Program July 18-22, 2001 University of Washington, Seattle, WA
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| Numbers in Italics indicate Program Abstract Number. | |||
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Wednesday July 18th |
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| 1-5pm | Meeting Registration at the dorms | Haggett | |
| 5-7pm | Dinner | McMahon | |
| 7-9:00pm | Presidential Symposium Analysis of Complex Systems |
HUB Ballroom | |
| Chair: | Brigid Hogan |
| 7:00 | Brigid Hogan (Vanderbilt
Medical School) Introduction |
| 7:05 | Linda Buck (Harvard
Medical School) The molecular architecture of odor and pheromone perception |
| 1 | 7:45 | Joanne Chory (Salk
Institute) Steroid hormones in plant development |
| 8:25 | Jay Hirsh (University
of Virginia) Bugs on drugs: Fruit flies as a model system for studying cocaine responsiveness |
| 9-11pm | Opening Reception and set up for Poster Session I | Upper Husky Den |
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Thursday July 19th |
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| 8am-5pm | Meeting Registration |
Kane Lobby |
| 8-9am | Funding Opportunities in Developmental Biology |
Kane 110 |
| Moderator: | Ida Chow (Society
for Developmental Biology) Domestic resources and international collaboration opportunities Agencies: NSF, NIH, MOD, HFSP |
| 8-9am |
Biotech Tutorial |
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| 9am-12:15pm | Concurrent Symposia with 15 min coffee break around 10:30am |
| 1. Cell Interactions and Signaling Pathways 1 | Kane 120 |
| Chair: | Philippe Soriano |
| 2 | 9:00 | Philippe
Soriano (Fred Hutchinson Cancer Research Center) PDGF Signaling in mouse development |
| 3 | 9:30 | Suzanne
Mansour (University of Utah) Fibroblast growth factors in ear development |
| 4 | 9:45 | Mark Krasnow (Stanford
Medical School) Genetic dissection of epithelial branching and oxygen response pathways in Drosophila |
| 5 | 10:15 | Laurel
Raftery (Massachusetts General Hospital) BMP and Sog-dependent thresholds of Smad activation during Drosophila dorsal-ventral patterning |
| 10:30 | Break |
| 10:45 | Jeff
Wrana (Samuel Lunenfeld Res. Inst., Canada) Interpreting TGFß and BMP signals during early development |
| 6 | 11:15 | Dominic
Norris (Harvard University) A nodal allelic series in the mouse |
| 7 | 11:30 | Malcolm
Whitman (Harvard Medical School) Nodal signals to Smads through Cripto-dependent and Cripto-independent mechanisms |
| 8 | 11:45 | Marek
Mlodzik (Mount Sinai School of Medicine) Non-canonical Frizzled signaling and epithelial planar polarity establishment |
| 2. Gametes: Formation and Function | Kane 110 |
| Chair: | Celeste Berg |
| 9 | 9:00 | Eleanor
Maine (Syracuse University) C. elegans ego-1 functions in germline development and RNAi |
| 10 | 9:30 | Erika Matunis
(Carnegie Institution of Washington) Jak Stat signaling controls male germline and somatic stem cell fate in Drosophila |
| 9:45 | Daphne
Preuss (University of Chicago) Mating interactions in Arabidopsis š signaling and species-specificity |
| 11 | 10:00 | Uta Wolke (Max-Planck
Institute, Germany) Multiple different modes of zebrafish VASA regulation |
| 10:30 | Break |
| 12 | 10:45 | Celeste
Berg (University of Washington) Multiple signaling pathways contribute to patterning and morphogenesis of the Drosophila egg |
| 13 | 11:15 | Karen
Bennett (University of Missouri-Columbia) Identifying C. elegans GLH partners by yeast two hybrid assays |
| 11:30 | Chris
Wylie (University of Cincinnati) Germ cells in the early mouse embryo |
| 14 | 12:00 | York
Marahrens (UCLA) Role of transvection in X-inactivation |
| 3. Cell Motility and Guidance | Kane 210 |
| Chair: | Lilianna Solnica-Krezel |
| 15 | 9:00 | Jeff
Hardin (University of Wisconsin-Madison) Molecular mechanisms regulating migration and adhesion of epithelial sheets in the C. elegans embryo |
| 16 | 9:30 | Erik
Lundquist (University of Kansas-Lawrence) Differential roles of Rac GTPase in axon pathfinding and cell corpse phagocytosis in C. elegans |
| 17 | 9:45 | Lilianna
Solnica-Krezel (Vanderbilt
University) Genetic control of convergent extension movements during zebrafish gastrulation |
| 18 | 10:15 | Gilbert Weidinger
(Max Planck Institute, Germany) Attraction, active migration and clustering of zebrafish primordial germ cells |
| 10:30 | Break |
| 19 | 10:45 | Pernille
Rorth (European Molecular Biology Laboratory, Germany) Regulation of cell migration during Drosophila oogenesis |
| 20 | 11:15 | Dan
Mellott (University of Victoria, Canada) ephB1 receptor and ephrins guide the migration of avian hindbrain neural crest |
| 21 | 11:30 | Darren
Gilmour (Max Planck Institute, Germany) A neural crest derived glial lineage in the zebrafish: coupling in vivo imaging and genetic analysis |
| 11:45 | Peter Devreotes
(Johns Hopkins University) Chemotactic gradient sensing in eucaryotic cells |
| 12:30-1:30pm | Lunch | McMahon |
| 1:30-3:30pm | Education
Workshop Ethics |
HUB Ballroom |
| Chair: | Karen Crawford |
| 1:30 | Mary
Claire King (University of Washington) Genomic views of human history |
| 22 | 2:00 | Anne
McLaren (University of Cambridge, U.K.) Human embryo and stem cell research: A view from Europe |
| 2:30 | Karen
Crawford (St. Mary's College of Maryland) - Moderator Discussion |
| 1:30-4pm | Poster Session I | Upper Husky Den |
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Numbers in Italics
indicate the Program Abstract Number. Odd number boards: Authors
present at posters 1:30-3pm |
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Cell Biology and
Development 24 B2 The dynamic cell wall of Acetabularia. E. Dunn, R. Froisland, M.E. Moffet, S. Mehri, N. Carpita, X. Huang, R. Kline, A. Mackay, M. Madison, I. Taylor, Z. Yang, G. Odell and D. Mandoli. Univ. of Washington, Seattle, WA, Purdue Univ., W. Lafayette, IN, Univ. of British Columbia, Canada and Univ. of California, Riverside, CA. 25 B3 Morpholino antisense-mediated depletion of SpRunt-1 causes mitotic abnormalities and late cleavage-stage arrest in sea urchin embryos. J.A. Coffman, S.J. Morris and C.W. Thurm. Stowers Inst. for Med. Res., Kansas City, MO. 26 B4 Incorporation of wheat germ agglutinin into the calcitic spicule of developing sea urchin embryos. N.M. Mozingo. Miami Univ., Oxford, OH. 27 B5 The role of the cytoskeleton during cytoplasmic cap formation and early cleavage in the squid, Loligo pealei. K. Crawford. St. Mary's Col. of Maryland, St. Mary's City, MD. 28 B6 Withdrawn 29 B7 Gurken- and microtubule-independent polarization of the Drosophila oocyte; rab11-mediated organization of the posterior pole. G.L. Dollar, E. Struckhoff, J. Michaud and R.S. Cohen. Univ. of Kansas, Lawrence, KS. 30 B8 Conserved signals and machinery for asymmetric RNA localisation in Drosophila oocytes and embryos. S.L. Bullock and D. Ish-Horowicz. Imperial Cancer Res. Fund, London, UK. 31 B9 Cytoskeleton networks affect Cdk1-cyclin B activities in the syncytial Drosophila embryo. J.Y. Ji, C. Trusty, C. Beach and G. Schubiger. Univ. of Washington, Seattle, WA. 32 B10 Rho1 is required for localization of adherens junction components during Drosophila development. C.R. Magie, D. Pinto-Santini and S.M. Parkhurst. Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 33 B11 Characterization of a novel dominant allele of the roughest-irregular chiasm C gene shows its requirement for pigment cell fate determination in the Drosophila retina. S. Octacilio-Silva, H. Araujo, L.C.H. Machado and R.G.P. Ramos. Ribeirão Preto Med. Sch., São Paulo, Brazil. 34 B12 Steroid regulation of programmed cell death during Drosophila development. C. Lee, C.R. Simon and E.H. Baehrecke. Univ. of Maryland, College Park, MD. 35 B13 Transcription factors E75 and MHR3 display a mosaic response to rising titers of ecdysone in Manduca epidermis. R.E. Langelan, K. Hiruma and L.M. Riddiford. Univ. of Washington, Seattle, WA. 36 B14 Spindle rotation in the early C. elegans embryo. A.J. Wright and C.P. Hunter. Harvard Univ., Cambridge, MA. 37 B15 Unraveling the role of calcium signaling in the early embryo. J.M. Squirrell, J. Ji, J.W. Walker and J.G. White. Univ. of Wisconsin, Madison, WI and Univ. of Washington, Seattle, WA. 38 B16 Cell cycle control during Xenopus tropicalis oocyte maturation. J-F. Bodart, D. Gutierrez and N. Duesbery. Van Andel Res. Inst., Grand Rapids, MI. 39 B17 Effects of localized acto-myosin contraction in Xenopus laevis oocytes. J. Thorn and B. Kay. Knox Col., Galesburg, IL and Univ. of Wisconsin, Madison, WI. 40 B18 Segregation of zebrafish muscle lineages: lineage relationships and cellular commitment. E. Hirsinger and M. Westerfield. Univ. of Oregon, Eugene, OR. 41 B19 When and where do zebrafish slow muscle precursors stop dividing? J.A. D'Angelo, M.J.F. Barresi and S.H. Devoto. Wesleyan Univ., Middletown CT. 42 B20 How your muscles know you've been working out: the IP3 pathway as a developmental signal in skeletal muscle. J.A. Powell, M.A. Carrasco, D.S. Adams, B. Drouet, J. Rios, M. Muller, M. Estrada, and E. Jaimovich. Smith Col., Northampton, MA, Univ. of Chile, Santiago, Chile and INSERM U-505, Paris, France. 43 B21 Bone morphogenetic protein function is required for the initial myofibrillogenesis in chick cardiogenesis. Y. Nakajima, T. Yamagishi and H. Nakamura. Saitama Med. Sch., Saitama, Japan. 44 B22 The zebrafish inv gene is required for left-right brain and heart development. J.J. Essner, X.-H. Wang, J. Zhang and H.J. Yost. Univ. of Utah, Salt Lake City, UT. 45 B23 Fates of neural crest cells in zebrafish Waardenburg-Shah model colourless/sox10 mutant. K.A. Dutton and R.N. Kelsh. Univ. of Bath, Bath, UK. 46 B24 Zebrafish mosaic eyes gene is required for tight junction formation in the retinal pigmented epithelium. A.M. Jensen and M. Westerfield. Univ. of Oregon, Eugene, OR. 47 B25 BMP11-a candidate negative regulator of olfactory neurogenesis. H.-H. Wu, P. Chern, J.E. Johnson and A.L. Calof. Univ. of California, Irvine, CA and Univ. of Texas Southwestern, Dallas, TX. 48 B26 Insulin-like growth factor-II modifies cell survival and proliferation during a discrete period of mouse embryogenesis. J.L. Burns and A.B. Hassan. Univ. of Oxford, Oxford, UK. 49 B27 Immunohistochemical localization of leukemia inhibitory factor, interleukins 1α, 1β and IL-6 in embryo-endometrium interface during implantation in the rhesus monkey. L. Dhawan, D. Ghosh and J. Sengupta. All India Inst. of Med. Sci., New Delhi, India. 50 B28 Exposure of human ES cells to TGF beta family members alters endoderm and mesoderm differentiation in vitro. M.T. Firpo, C. Ayala, C. Catuar, J.J. Meneses, G. Perez and R.A. Pedersen. Univ. of California, San Francisco, CA. Cell Interactions 51 B29 The role of callose in root gravitropism. L.C. Enns, R.E. Cleland, K.U. Torii and L. Comai. Univ. of Washington, Seattle, WA. 52 B30 Peripodial membrane cells regulate imaginal disc development in Drosophila. M.C. Gibson and G. Schubiger. Univ. of Washington, Seattle, WA. 53 B31 Functional characterization of the Lim1 gene during gastrulation. N.A. Hukriede, D.L. Weeks and I.B. Dawid. NICHD, NIH, Bethesda, MD and Univ. of Iowa, Iowa City, IA. 54 B32 Early pregnancy factor in embryonic development and during pregnancy in the dasyurid marsupial, Sminthopsis macroura (Spencer). Y.P. Cruz, L. Selwood, H. Morton and A.C. Cavanagh. Oberlin Col., Oberlin, OH, Univ. of Melbourne, Melbourne, Australia and Univ. of Queensland, Brisbane, Australia. 55 B33 Survey of surface characteristics of human cancer cells using derivatized agarose beads. G.R. Weerasinghe, M.R. Khurrum, E.S. Soriano, O. Badali, T. Sakhakorn, L. Kirszenbaum, L. Ngo, K. Abedi, C. Harieg, V.M. Navarro, M. Barajas, A. Martino, D. Toledo, J. Ching, M.W. Soccar, D. Khatibi, R. Riman, C.A. Bulan, G. Zem, K.M. Cork, S. Meshkinfam, R. Nejathaim and S.B. Oppenheimer. California State Univ., Northridge, CA. Cell Motility and Guidance 56 B34 Filopodial initiation and a novel filament organizing center, the focal ring. K.W. Tosney, K. Balazovich and M. Steketee. Univ. of Michigan, Ann Arbor, MI. 57 B35 Morphogenetic domains and their ontogeny in the zebrafish gastrula. M.S. Cooper and L.A. D'Amico. Univ. of Washington, Seattle, WA. 58 B36 Stuck in place is a new locus required for proper cell migration in Drosophila. J.A. McDonald and D.J. Montell. Johns Hopkins Univ. Sch. of Med., Baltimore, MD. 59 B37 Identification of genes controlling longitudinal guidance in the nematode C. elegans. A. Adeleye, F. Vedulla and E. Stringham. Trinity Western Univ., Langley, Canada. 60 B38 The regulation of bud elongation and branching program initiation during lacrimal gland development. H. Makarenkova and R. Lang. Skirball Inst., NYU Sch. of Med., New York, NY. 61 B39 Hindbrain neural crest cells require integrins for epithelial-mesenchyme transition, but not for pathfinding. R.L. Atkins, D. Wang and R.D. Burke. Univ. of Victoria, Victoria, Canada. 62 B40 Avian neural crest migration guidance, from microns to millimeters. A.J. Ewald and S.E. Fraser. Caltech, Pasadena, CA. 63 B41 Quantitative analysis of germ cell movements in tissue explants. K.A. Molyneaux, K. Schaible and C. Wylie. Children's Hosp., Cincinnati, OH. 64 B42 Regulation of Doublecortin, a protein implicated in cortical neuron migration. B.T. Schaar, K. Kinoshita, A. Hyman and S.K. McConnell. Stanford Univ., Stanford, CA and Max Planck Inst. of Mol. Cell Biol. and Genet., Dresden, Germany. Body Plan 65 B43 Embryonic handedness choice in C. elegans involves a Gα protein encoded by the spn-1 gene. W.B. Wood, B. Robertson and D. Bergmann. Univ. of Colorado, Boulder, CO. 66 B44 Spatial expression patterns of Hox genes during development of the sepiolid squid, Euprymna scolopes. P.N. Lee, P. Callaerts, B. Hartmann, D. Choy, M.Q. Martindale and H.G. de Couet. Univ. of Hawaii at Manoa, Honolulu, HI. 67 B45 A sensitized haploid screen for zebrafish gastrulation mutants. D.H. Lee, F.A. Olale, T. Bruno, D. Yelon and A.F. Schier. Skirball Inst., NYU Sch. of Med., New York, NY. 68 B46 Pitx2c-gfp trangenic zebrafish identify regions of asymmetric gene expression in the central nervous system. H.J. Yost, E.B. Harris and J.J. Essner. Univ. of Utah, Salt Lake City, UT. 69 B47 Arkadia is essential for specification of antero-posterior and left-right axes. P.M. Timmons, R.L. Andrew, J.J. Walsh, D. Swan, R. Arkell and V. Episkopou. MRC Clin. Sci. Ctr., London, UK. 70 B48 Withdrawn 71 B49 Inadequate differentiation of endoderm/mesoderm derived cells in mouse l7Rn3 mutant embryos. H. Nakamura, S.E. Thomas and M.J. Justice. Baylor Col. of Med., Houston, TX. 72 B50 Functional analyses of bone morphogenetic proteins during pattern formation and organogenesis in mouse embryos. Y. Mishina, C. Trisha and S. Kishigami. Natl. Inst. of Envrn. Hlth. Sci., NIH, Res. Triangle Park, NC. 73 B51 Evidence that delta and forkhead genes interact during somitogenesis in the mouse. B. Wilm and B.L.M. Hogan. Vanderbilt Univ. Sch. of Med., Nashville, TN. 74 B52 The role of midline FGF8 in left-right axis specification in the rabbit. M. Blum and A. Fischer. Forschungszentrum Karlsruhe, Karlsruhe, Germany. Morphogenesis 75 B53 Complete live Drosophila embryogenesis: time-lapse movie of histone-GFP embryos with multiphoton microscopy. J.Y. Ji, J. Squirrell, D. Hurley and G. Schubiger. Univ. of Washington, Seattle, WA and Univ. of Wisconsin, Madison, WI. 76 B54 Genetic analysis of isometric growth in the zebrafish. M.K. Iovine and S.L. Johnson. Washington Univ. Sch. of Med., St. Louis, MO. 77 B55 Growth control in the zebrafish, Danio Rerio. M.I. Goldsmith, R. Waterman and S.L. Johnson. Washington Univ. Sch. of Med., St. Louis, MO. 78 B56 Zebrafish Paxillin and FAK are necessary for normal development. C.A. Henry, B.D. Crawford and M.B. Hille. Univ. of Washington, Seattle, WA. 79 B57 One-eyed pinhead dependent cell behavior in the zebrafish blastula. R.M. Warga and D.A. Kane. Univ. of Rochester, Rochester, NY. 80 B58 A relationship of epiboly with other cellular movements in the zebrafish gastrula. D.A. Kane, K.N. DelKanic and R.M. Warga. Univ. of Rochester, Rochester, NY. 81 B59 Cell internalization during zebrafish gastrulation. A.J. Carmany-Rampey and A.F. Schier. Skirball Inst., NYU Sch. of Med., New York, NY. 82 B60 3D-time lapse analysis of Xenopus gastrulation movements using μMRI. C. Papan, S.S. Velan, S.E. Fraser and R.E. Jacobs. Beckman Inst., California Inst. of Technol., Pasadena, CA. 83 B61 The role of the Rho GTPases in controlling cell movements: a close look into the fine mechanics of Xenopus gastrulation. E. Tahinci and K. Symes. Boston Univ. Sch. of Med., Boston, MA. 84 B62 Involvement of PAR-6 in the regulation of gastrulation cell movement in Xenopus early development. S-C. Choi and J-K. Han. Pohang Univ. of Sci. and Technol., Pohang, Republic of Korea. 85 B63 Migration and mechanics during closure of the mesendodermal mantle in Xenopus laevis. L.A. Davidson, R. Keller and D.W. DeSimone. Univ. of Virginia Hlth. Syst., Sch. of Med., Charlottesville, VA. 86 B64 Cell autonomous effect of the Wnt pathway in Spemann organizer formation in Xenopus laevis. A. Vonica and B.M. Gumbiner. Sloan-Kettering Inst., New York, NY. 87 B65 Identifying neurulation genes in chick. J-F. Colas and G.C. Schoenwolf. Univ. of Utah Sch. of Med., Salt Lake City, UT. 88 B66 Exploring a genetic basis for neurulation in zebrafish. R.M. Brewster, A.L. Rubinstein and M.E. Halpern. Carnegie Inst. of Washington, Baltimore, MD. 89 B67 A role for midline signalling in neural convergence and extension. C.M. Scott-Whitlow, C.R. Heitz and R.E. Keller. Univ. of Virginia, Charlottesville, VA. 90 B68 The role of the AP-2α transcription factor in ventral body wall closure. S.L. Brewer, S. Donaldson and T. Williams. Yale Univ., New Haven, CT and Univ. of Colorado Hlth. Sci. Ctr., Denver, CO. 91 B69 Epithelial-mesenchymal transition and neural crest differentiation: several routes to one outcome. D.F. Newgreen, S. Lewis and J. Minichiello. Murdoch Childrens Res. Inst., Parkville, Australia. 92 B70 Neural crest cell motility in valproic acid. D. Wiens, L. Fuller and S. Cornelius. Univ. of Northern Iowa, Cedar Falls, IA. 93 B71 Genetic dissection of c-kit function during embryonic melanocyte development in the zebrafish. J.F. Rawls and S.L. Johnson. Washington Univ. Sch. of Med., St. Louis, MO. 94 B72 The flat top mutation affects the differentiation of post-otic neural crest. T.H. Linbo, C.B. Moens and D.W. Raible. Univ. of Washington, Seattle, WA and Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 95 B73 Time-lapse analysis of somite formation in whole chick embryo explants. P.M. Kulesa and S.E. Fraser. California Inst. of Technol., Pasadena, CA. 96 B74 Contribution of somitic cells to the avian axial skeleton and hypaxial musculature. D.J.R.Evans. Cardiff Univ., Cardiff, Wales, UK. 97 B75 Dorsal, axial morphogenesis, deposition of the ECM protein fibrillin, and sonic hedgehog expression are all dependent on the notochord-somite boundary. P. Skoglund, A. Rolo and R.E. Keller. Univ. of Virginia, Charlottesville, VA. 98 B76 The upstream ectoderm enhancer in Pax6 has an important role in lens induction. P.V. Dimanlig and R.A. Lang. Skirball Inst. for Biomolec. Med., New York Univ. Sch. of Med., New York, NY. 99 B77 Chondrogenesis of the otic capsule during the chicken inner ear development. W. Chang, P. ten Dijke and D.K. Wu. NIDCD/NIH, Rockville, MD and The Netherlands Cancer Inst., Amsterdam, The Netherlands. 100 B78 Mechanisms of left-right asymmetric digestive organ morphogenesis. J.L. Keene, D.R. Knutson and N.M. Nascone-Yoder. Eckerd Col., St. Petersburg, FL. 101 B79 The Ret signaling system and pronephric duct migration in axolotl and Xenopus embryos. J. Drawbridge, M.E. Kite, C.M. Meighan and R. Lumpkins. Rider Univ., Lawrenceville, NJ. 102 B80 Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis. A. Mailleux, D. Tefft, D. Ndiaye, N. Itoh, J-P. Thiery, D. Warburton and S. Bellusci. CNRS/Institut Curie, Paris, France, Childrens Hosp. Los Angeles Res. Inst., Univ. of Southern California, Los dAngeles, CA and Kyoto Univ., Kyoto, Japan. B 103 B81 Absence of ventricular ballooning segments in embryos lacking the homeobox gene Nkx2-5. C. Biben, L. McDonald and R.P. Harvey. Victor Chang Cardiac Res. Inst., Darlinghurst, Australia. 104 B82 Withdrawn 105 B83 Characterization of the roles of a novel T-box transcription factor, hrT, during cardiovascular development in zebrafish. D.P. Szeto, K.J.P. Griffin and D. Kimelman. Univ. of Washington, Seattle, WA. 106 B84 Distinct mechanisms regulate slow muscle development during the embryonic and larval periods. M.J.F. Barresi, J.A. D'Angelo, L.P. Hernandez and S.H. Devoto. Wesleyan Univ., Middletown, CT. 107 B85 A new semi-dominant mutation linked to Shh causes preaxial polydactyly. J.O. Bush and R.J. Jiang. Univ. of Rochester Sch. of Med. and Dent., Rochester, NY. 108 B86 Engrailed1 is critical for repression of nail type differentiation in mouse. P. Kraus, C. Tong and C.A. Loomis. NYU Sch. of Med., New York, NY. 109 B87 Surprising expression pattern of cholesterogenic enzymes during embryonic mouse development. D. Laubner, R. Breitling and J. Adamski. GSF, Natl. Res. Ctr., Neuherberg, Germany. 110 B88 DWnt-4 cooperates with Dfrizzled-2 to regulate cell motility during ovarian morphogenesis. E.D. Cohen and E. Wilder. Univ. of Pennsylvania Sch. of Med., Philadelphia, PA. 111 B89 Genetic screen identifies Bicaudal-C, Kinesin heavy chain, and Shark as enhancers of bullwinkle. D.H. Tran and C.A. Berg. Univ. of Washington, Seattle, WA. 112 B90 Planarian regeneration: a classic problem enters the era of functional genomics.. P.A. Newmark, S. Robb, R. Juste, S. Saha and A. Sanchez Alvarado. Carnegie Inst. of Washington, Baltimore, MD. 113 B91 Pharynx tubulogenesis during C. elegans development. M.F. Portereiko and S.E. Mango. Univ. of Utah, Salt Lake City, UT. 114 B92 Development of the Acetabularia acetabulum vacuole: a model for vacuolar morphogenesis and inheritance. P.A. Garland, D. Ngo, P. Luethe and D. Mandoli. Univ. of Washington, Seattle, WA. 115 B93 The invA gene of Volvox encodes a novel kinesin that is required for inversion of the embryo. I. Nishii and D.L. Kirk. Washington Univ., St. Louis, MO. Organogenesis 116 B94 Regulation of organ shape in Arabidopsis by ERECTA receptor-like kinase. E.D. Shpak, C.A.B. Josefsson and K.U. Torii. Univ. of Washington, Seattle WA. 117 B95 Specification of organ identity by the C. elegans FoxA protein PHA-4. J. Gaudet, M. Horner, S. Kim and S.E. Mango. Univ. of Utah, Salt Lake City, UT and Stanford Univ. Med. Sch., Stanford, CA. 118 B96 Molecular integration of signaling activities and tissue-specific transcription factors during visceral mesoderm specification of Drosophila. H.H. Lee, S. Zaffran and M. Frasch. Mount Sinai Sch. of Med., New York, NY. 119 B97 BMP signaling is important for mesoderm specification and regulation of neurectoderm growth in mouse embryonic development. S. Miura, M.D. Tallquist, P. Soriano and Y. Mishina. NIEHS/NIH, Research Triangle Park, NC and Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 120 B98 Chick-quail chimerism proves the mesenchymal origin of bursal secretory dendritic cell. N. Nagy, A. Magyar and I. Olah. Semmelweis Univ., Budapest, Hungary. 121 B99 Tissue-specific knockout of smoothened reveals a critical role for hedgehog signaling in chondrocyte proliferation. F. Long, X. Zhang and A.P. McMahon. Harvard Univ., Cambridge, MA. 122 B100 Study on the role of epidermal growth factor in chondrogenesis. K.M. Ng, S.E. Cheah, W.C. Wong and S.Y. Chan. Univ. of Hong Kong, Hong Kong, China and Univ. of Tokyo, Tokyo, Japan. 123 B101 Commitment and differentiation of avian head muscles. D. Noden, X. Borue and R. Marcucio. Cornell Univ., Ithaca, NY and Univ. of California, San Francisco, CA. 124 B102 Evolutionary conservation of Hoxc13. R. Thummel, M.P. Sarras and A.R. Godwin. Univ. of Kansas Med. Ctr., Kansas City, KS. 125 B103 Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a role of BMP and SHH signaling in mammalian palatogenesis. Z. Zhang, Y. Song, X. Zhao, X. Zhang and Y. Chen. Tulane Univ., New Orleans, LA. 126 B104 Wnt pathway members in the development of hair and other skin appendages. U. Gat, B.J. Merrill and E. Fuchs. Hebrew Univ., Jerusalem, Israel and Univ. of Chicago, Chicago, IL. 127 B105 The role of Msx1 and Bmp4 in digit tip regeneration of mice. M. Han and K. Muneoka. Tulane Univ., New Orleans, LA. 128 B106 Genetic analysis of zebrafish fin regeneration. K.D. Poss, A. Nechiporuk, S.L. Johnson and M.T. Keating. Children's Hosp., Boston, MA and Washington Univ., St. Louis, MO. 129 B107 A role for the LIM-domain co-factors Clim2/Ldb-1/Nli in hair follicle regulation. E.I. Kudryavtseva, I. Chen, T.M. Sugihara and B. Andersen. UCSD, La Jolla, CA and UCI, Irvine, CA. 130 B108 Overexpression of a soluble dominant negative FGFR1 and SPRY2 affects craniofacial and feather development. M. Mandler and A. Neubuser. Inst. of Molec. Pathol., Vienna, Austria. 131 B109 In vitro studies of the discrete steps in the development of mouse Rathke's pouch. A.S. Gleiberman, E.I. Kudryavtseva and M.G. Rosenfeld. UCSD, La Jolla, CA. 132 B110 Pitx2 is required at multiple stages of pituitary organogenesis: formation of the pituitary primoridum and cell specification. H. Suh, P.J. Gage, J. Drouin and S.A. Camper. Univ. of Michigan, Ann Arbor, MI and Inst. of Clin. Res., Montreal, Canada. 133 B111 Dorsal-ventral patterning in Xenopus inner ear: ablation and Wnt-3a studies. C.A. Forristall and A. Collazo. Univ. of Redlands, Redlands, CA and House Ear Inst., Los Angeles, CA. 134 Withdrawn 465* B112 Ras1 is required cell autonomously in the Drosophila follicular epithelium for pipe repression and dorsal follicle cell migration. K.E. James and C.A. Berg. Univ. of Washington, Seattle, WA. * Poster moved from Poster Session II, B175 135 B113 Withdrawn 136 B114 The role of Eya genes during mammalian organogenesis. P. Xu, R. Maas, C. Buller, H. Peters and X. Xu. McLaughlin Res. Inst., Great Falls, MT. 137 B115 FGF receptor and BMP7 signaling cooperate in lens induction. S.C. Faber, H.P. Makarenkova, P. Dimanlig and R.A. Lang. Skirball Inst. and New York Univ. Med. Ctr., New York, NY. 138 B116 A role for sonic hedgehog in fetal thymus development. B.A. Moore and N.R. Manley. Med. Col. of Georgia, Augusta, GA. 139 B117 ITIH-4, a serine protease inhibitor plays a prominent functional role in IL-6 induced hepatocyte formation. C. Banumathy, Y. Tang, C. Fox, B. Mishra and L. Mishra . DVAMC, Washington, DC and Fels Cancer Inst., Temple Univ., Philadelphia, PA, NHGRI, NIH, Bethesda, MD and Walter Reed Army Med. Ctr., Washigton, DC. 140 B118 Expression of Prox1 during liver development. Z.D. Burke, B. Sosa-Pineda, J. Wigle and G. Oliver. Saint Jude Children's Res. Hosp., Memphis, TN. 141 B119 The roles of FGFs, BMP4, and SHH in transdifferentiation of mouse tracheal epithelium in mesenchyme-free culture. B.A. Hyatt, J.A. Whitsett and J.M. Shannon. Children's Hosp. Med. Ctr., Cincinnati, OH. 142 B120 Hlx homeobox transcription factor downstream targets identified in Hlx knockout mesenchymal cell lines. M.D. Bates, D.A. Persons, L.C. Schatzman, R.P. Harvey, and S.S. Potter. Children's Hosp. Med. Ctr., Cincinnati, OH, St. Jude Children's Res. Hosp., Memphis, TN, and St. Vincent's Hosp., Darlinghurst, Australia. 143 B121 The homeobox gene Hex is necessary for liver and lung development. C.W. Bogue, C.M. Wilson, H. Vasavada and H.C. Jacobs. Yale Univ. Sch. of Med., New Haven, CT. 144 B122 The correct regional specification and function of the stomach requires mesenchymal-epithelial signaling cascades controlled by Hoxa5. J. Aubin, U. Dery, P. Chailler and L. Jeannotte. Univ. Laval, Univ. of Quebec, L'Hotel-Dieu de Quebec, and Univ. of Sherbrooke, Quebec, Canada. 145 B123 Using a novel gut culture system to analyse the influence of known and novel genes on intestinal epithelial differentiation. H.E. Abud, C.N. Johnstone, N. Watson, N.C. Tebbutt, M. Ernst and J.K. Heath. Ludwig Inst. for Cancer Res., Royal Melbourne Hosp., Melbourne, Australia. 146 B124 A new Abd-B class homeobox gene (HgHbox12) from an echinoderm, and its expression during intestinal regeneration. A.T. Mendez-Merced and J.E. Garcia-Arraras. Univ. of Puerto Rico, Rio Piedras, Puerto Rico. 147 B125 Two actin isoforms are differentially expressed during regenerative organogenesis in the echinoderm Holothuria glaberrima. J.L. Roig-Lopez, C. Lasalde and J.E. Garcia-Arraras. Univ. of Puerto Rico-Rio Piedras, San Juan, PR. 148 B126 Notochord and endothelial signals during patterning of the Xenopus endoderm. O. Cleaver and D. Melton. Harvard Univ., Cambridge, MA. 149 B127 Gata4 and Gata6 function in the mouse embryonic pancreas. D.C. Goldman and L. Sussel. Univ. of Colorado Hlth. Sci. Ctr., Denver, CO. 150 B128 Cloning and functional characterization of Xenopus Pod-1, a bHLH transcription factor expressed in the developing pronephric kidney. S.R. Eid and A.W. Brandli. Swiss Fed. Inst. of Technol., Zurich, Switzerland. 151 B129 The biology of becoming: cell fate decisions during embryonic kidney development. K.A. McLaughlin, M.S. Rones and M. Mercola. Harvard Med. Sch., Boston, MA. 152 B130 Differential regulation of pax2 and lim1 in the chick embryonic kidney. R.G. James and T.M. Schultheiss. Beth Israel Deaconness Med. Ctr., Boston, MA. 153 B131 Visualization of kidney branching morphogenesis. T. Watanabe, S. Srinivas, C.S. Lin, R. Shakya and F. Costantini. Columbia Univ., New York, NY and Natl. Inst. of Med. Res., London, UK. 154 B132 Regulation of metanephric kidney development by Gdf-11. A. Esquela Kerscher, A. McPherron and S-J. Lee. Johns Hopkins Sch. of Med., Baltimore, MD. 155 B133 Role of the transcription factors Pax2 and Pax8 in nephric lineage determination. M. Bouchard, A. Souabni and M. Busslinger. Inst. for Molec. Pathol., Vienna, Austria. 156 B134 The role of Wnts in the development of the kidney collecting ducts. T.J. Carroll, M. Ishibashi, B. Parr and A.P. McMahon. Harvard Univ., Cambridge, MA. 157 B135 The role of sonic hedgehog during mouse kidney development. J. Yu, T.J. Carroll, P.M. Lewis and A.P. McMahon. Harvard Univ., Cambridge, MA. 158 B136 Kidney development depends on a novel reciprocal signaling loop mediated by vitamin A and ret. E. Batourina, S. Gim, N. Bello, M. Shy, M. Clagett-Dame, S. Srinivas, F. Costantini and C. Mendelsohn. Columbia Univ., New York, NY, Univ. of Wisconsin-Madison, Madison, WI and Natl. Inst. for Med. Res., Mill Hill, London, U.K. 159 B137 Functional characterization of the Hey bHLH gene family. M. Gessler, K. Knobeloch, N. Schumacher, K. Amann, N. Golenhofen and C. Leimeister. Univ. of Wuerzburg, Wuerzburg, Germany, Freie Univ., Berlin, Germany and Univ. of Erlangen, Germany. 160 B138 A role for XWnt-11 in Xenopus cardiogenesis. P. Pandur and M. Kuehl. Univ. of Goettingen, Goettingen, Germany. 161 B139 In vivo study of ANF regulation by Nkx2-5 and GATA-4 in transgenic Xenopus laevis embryos. E.M. Small and P.A. Krieg. Univ. of Arizona Hlth. Sci. Ctr., Tucson, AZ. 162 B140 Genetic regulation of myocardial differentiation in zebrafish. B.R. Keegan, R.K. Ho and D.L. Yelon. Skirball Inst. of Biomolec. Med., New York Univ. Med. Ctr., New York, NY and Princeton Univ., Princeton, NJ. 163 B141 Causes and consequences of an atrium-specific developmental defect in zebrafish. E. Berdougo, D.Y.R. Stainier and D. Yelon. Skirball Inst., New York Univ. Med. Ctr., New York, NY and Univ. of California at San Francisco, San Francisco, CA. 164 B142 A role for FGF signaling in the specification of avian heart tissue. T.M. Schultheiss and B.H. Alsan. Beth Israel Deaconess Med. Ctr., Harvard Med. Sch., Boston, MA. 165 B143 Cardiofunk, a zebafish mutation disrupting atrioventricular valve formation. T. Bartman and D.Y.R. Stainier. Univ. of California, San Francisco, CA. 166 B144 Bves: prototype of a new class of cell adhesion molecules expressed during coronary artery development. A.M. Wada, D.E. Reese and D.M. Bader. Vanderbilt Univ., Nashville, TN. 167 B145 The zebrafish gene pandora regulates myocardial differentiation. J.L. Feldman, D.Y.R. Stainier and D.L. Yelon. Skirball Inst. of Biomolec. Med., New York Univ. Med. Ctr., New York, NY and Univ. of California, San Francisco, San Francisco, CA. 168 B146 Notch signaling in left-right determination during mouse development. L.T. Krebs, I. Welsh, C.H. Tenney, Y. Lan, R. Jiang, T. O'Brien and T. Gridley. The Jackson Lab., Bar Harbor, ME. 169 B147 Development of the hematopoietic tissue in the Penaeid shrimp Sicyonia ingentis. P.L. Hertzler and O.J. Sepulveda Villet. Central Michigan Univ., Mt. Pleasant, MI. 170 B148 Hedgehog signaling and yolk sac vasculogenesis. N.A. Byrd, S. Becker, P.F. Maye, J.A. McMahon, X.M. Zhang, A.P. McMahon and L.B. Grabel. Wesleyan Univ., Middletown, CT, and Harvard Univ., Cambridge, MA. 171 B149 Endoderm is not necessary for vascular specification, but is necessary for endothelial tube formation. S.A. Vokes and P.A. Krieg. Univ. of Arizona Hlth. Sci. Ctr. Tucson, AZ. 172 B150 Intersomitic arteries and intersomitic veins form via distinct mechanisms. S. Isogai, N.D. Lawson, S. Torrealday and B.M. Weinstein. NICHD, NIH, Bethesda, MD. 173 B151 Notch signaling is required for arterial differentiation and repression of venous cell fate during embryonic vascular development. N.D. Lawson, N. Scheer, V.N. Pham, C-H. Kim, A.B. Chitnis, J.A. Campos-Ortega and B.M. Weinstein. NICHD, NIH, Bethesda, MD and Univ. of Koln, Cologne, Germany. 174 B152 Competing pathways in testis organogenesis. B. Capel, C. Tilmann, J. Schmahl, J. Brennan and H.H.C. Yao. Duke Univ. Med. Ctr., Durham, NC. 175 B153 Sex specific gene expression during mouse gonad development. D. Menke and D.C. Page. MIT, Cambridge, MA. 176 B154 The PDGF alpha receptor is required for interstitial specification and cord formation in the mammalian testis. C.E. Tilmann, J.R. Brennan and B. Capel. Duke Univ. Med. Ctr., Durham, NC. 177 B155 The role of FGF9 and proliferation in sex determination. J.P. Schmahl, J. Colvin, D. Ornitz and B. Capel. Duke Univ., Durham, NC. 178 B156 Direct evidence that Sry is expressed in pre-Sertoli cells and that Sertoli and granulosa cells develop from a common precursor. K.H. Albrecht and E.M. Eicher. Jackson Lab., Bar Harbor, ME. 179 B157 Sexually dimorphic vascular development in the XY mouse gonad. J.R. Brennan, and B. Capel. Duke Univ. Med. Ctr., Durham, NC. 180 B158 Decisive roles of meiotic germ cells in sex determination of mammalian gonads. H.H.C. Yao and B. Capel. Duke Univ. Med. Ctr., Durham, NC. 181 B159 Assessment of candidate ovarian determining genes. K.A. Loffler, J. Bowles and P. Koopman. Univ. of Queensland, Brisbane, Australia. 182 B160 Effects of acute nutritional stress during the pre-implantation stage of gestation on reproductive functions in the mouse. J.F. Rosario, J. Sengupta and D. Ghosh. All India Inst. of Med. Sci., New Delhi, India. 183 B161 An effects on teratogenicity by exposure with cyclophosphamide during early organogenic period. S.J. Kwack, H.S. Kim and K.L. Park. Natl. Inst. of Toxicol. Res., Seoul, Korea. Gametogenesis and Fertilization 184 B162 POP2, a gene required for guidance of Arabidopsis pollen tubes, is similar to class III omega aminotransferases. R. Palanivelu, L.K. Wilhelmi and D. Preuss. Univ. of Chicago, Chicago, IL. 185 B163 L-HGP, a heterodimeric mucin-like protein with acrosome protective properties. S.E. Arranz, R. Cabrera and M.O. Cabada. Univ. Nacional de Rosario, Rosario, Argentina. 186 B164 Identification of a sperm lysin in the frog Lepidobatrachus laevis. V. Hutchins-Latham and E.J. Carroll, Jr. California State Univ., Northridge, CA. 187 B165 Xenopus sperm display three swimming patterns: ideal corkscrew, uncoupled corkscrew, and idle. S. Naqvi, A. Kittelson and D.E. Chandler. Arizona State Univ., Tempe, AZ. 188 B166 Allurin, a 21 kD sperm chemoattractant from Xenopus egg jelly, is related to mammalian sperm-binding proteins of the CRISP family. X. Xiang, J. Olson, J. Johnson, A. Rawls, A.L. Bieber and D.E. Chandler. Arizona State Univ., Tempe, AZ. 189 B167 Isolation of allurin, a 21 kD sperm chemoattractant protein from Xenopus laevis egg jelly: purification and characterization. J.H. Olson, X. Xiang, T. Ziegert, A. Kittelson, K. Stone, D. Simh, D.E. Chandler and A.L. Bieber. Arizona State Univ., Tempe, AZ. 190 B168 Identification of a conserved candidate gene for the spermiogenesis defect in the mouse mutant quaking. D. Lorenzetti and M.J. Justice. Baylor Col. of Med., Houston, TX. 191 B169 Sperm nuclear basic proteins in Drosophila simulans undergoing Wolbachia-induced cytoplasmic incompatibility. H. Harris and H. Braig. Univ. of Wales, Bangor, United Kingdom. 192 B170 dpo is required in the niche cells to maintain germline stem cells in the Drosophila ovary. T. Xie, C. Doan, X. Song and A. Spradling. Stowers Inst. for Med. Res., Kansas City, MO and Carnegie Inst. of Washington, Baltimore, MD. 193 B171 Investigating egalitarian's function during Drosophila oogenesis. C. Navarro, J.Z. Morris and R. Lehmann. New York Univ. Med. Ctr., Skirball Inst., New York, NY. Neural Development 194 B172 Roles of Notch/Abl/Dab and Notch/Su(H) signaling pathways in Drosophila axon patterning. M. Le Gall, M. Gates, C. DeMattei and E. Giniger. Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 195 B173 A targeted gain of function screen to identify genes involved in axon guidance in the Drosophila CNS. V.L. McGovern and M.A. Seeger. Ohio State Univ., Columbus, OH. 196 B174 Alternate isoforms of Lola regulate the coordinated expression of many networks of axon guidance molecules in Drosophila. S. Goeke, E.A. Greene and E. Giniger. Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 197 B175 Getting from here to there: axon guidance in the periphery. J. Eberhart, M. Swartz, E.B. Pasquale, S.A. Koblar and C.E. Krull. Univ. of Missouri-Columbia, Columbia, MO, The Burnham Inst., La Jolla, CA and Univ. of Adelaide, Adelaide, Australia. 198 B176 Pioneer axon guidance errors in Pax6 mutants are rescued by whole mouse embryo electroporation. G.S. Mastick. Univ. of Nevada, Reno, NV. 199 B177 R-cadherin is a Pax6-regulated, growth-promoting cue for pioneer axons. G.L. Andrews and G.M. Mastick. Univ. of Nevada, Reno, NV. 200 B178 What is the role of the growth cone kinase Cdk5 in axon patterning? L. Connell-Crowley, D. Vo and E. Giniger. Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 201 B179 Identifying C. elegans UNC-4 targets. S.E. Von Stetina and D.M. Miller III. Vanderbilt Univ., Nashville, TN. 202 B180 Lox6, a leech Dfd ortholog, may play a role in the patterning of the nervous systems. M.E. Mercado-Pimentel and G.O. Aisemberg. Lehman Col. of CUNY, Bronx, NY. 203 B181 Nerfin-1, a member of the conserved ein zn-finger subfamily, is required for proper cell fate specification in the developing Drosophila nervous system.. A. Kuzin, C. Stivers, T. Brody and W.F. Odenwald. NINDS, Bethesda, MD. 204 B182 A cDNA screen for Drosophila genes that are dynamically expressed during the generation of embryonic neural lineages. T. Brody, C. Stivers, A. Kuzin and W.F. Odenwald. NINDS, NIH, Bethesda, MD. 205 B183 Timing and competence of neural crest formation. M.L. Basch, M.A.J. Selleck and M. Bronner-Fraser. California Inst. of Technol., Pasadena, CA and Univ. of Southern California, Sch. of Med., Los Angeles, CA. 206 B184 Underlying mesoderm is not required for neural crest induction. J.W. Ragland and D.W. Raible. Univ. of Washington, Seattle, WA. 207 B185 Colgate b382 is required for the normal development of subsets of neural crest cells, primary neurons and the pectoral fin. R.M. Nambiar and P.D. Henion. Ohio State Univ., Columbus, OH. 208 B186 Survival and glial fate acquisition of neural crest cells are regulated by an interplay between the transcription factor Sox10 and extrinsic combinatorial signalling. L. Sommer, C. Paratore, D.E. Goerich, U. Suter and M. Wegner. Swiss Fed. Inst. of Technol., Zurich, Switzerland and Univ. of Erlangen-Nurnberg, Erlangen, Germany. 209 B187 Primary neuronal differentiation and orientated cell division in Xenopus. A.D. Chalmers, B. Strauss and N. Papalopulu. Univ. of Cambridge, Cambridge, UK. 210 B188 Regulation of neurogenesis by Hairy/Enhancer of split related proteins in Xenopus laevis. M. Solter, T. Hollemann, V. Gawantka, C. Niehrs, E.J. Bellefroid and T. Pieler. Univ. Gottingen, Gottingen, Germany, Deutsches Krebsforschungszentrum, Heidelberg, Germany and Univ. libre de Bruxelles, Gosselies, Belgium. 211 B189 A role for Dlx3 in neural plate border formation. J.M. Woda, J. Pastagia, K.B. Artinger and M. Mercola. Harvard Med. Sch., Boston, MA. 212 B190 Xrx1 controls neuronal differentiation in the anterior neural plate. M. Andreazzoli, G. Gestri and G. Barsacchi. Universita' di Pisa, Italy. 213 B191 Notch-mediated fate specification in the zebrafish neural tube. H. Park, A. Mehta, J. Richardson and B. Appel. Vanderbilt Univ., Nashville, TN. 214 B192 wimple, a mouse mutation that plays a role in Shh-dependent neural tube patterning. D. Huangfu and K.V. Anderson. Sloan-Kettering Inst. and Cornell Univ., New York, NY. 215 B193 Neurogenin1 functions as a switch between neuronal and non-neuronal fates in zebrafish lateral neural plate. R.A. Cornell and J.S. Eisen. Univ. of Oregon, Eugene, OR. 216 B194 G protein signaling in the developing zebrafish central nervous system. G.M. Kelly, B. Vanderbeld and M. Knowlton. Univ. of Western Ontario, London, Canada. 217 B195 A novel gene, axotrophin, is important in neural development. G.E. Lyons, M.A. Haendel, M. Epstein, M. Wagner and J. Johnson. Univ. of Wisconsin Med. Sch., Madison, WI. 218 B196 Effects of temperature on the gene expression of aromatase and estrogen receptors in the developing tilapia brain. C-L. Tsai. Natl. Sun Yat-sen Univ., Kaohsiung, Taiwan. 219 B197 Regulation of extracellular matrix-mediated contact inhibition of growth in the developing nervous system. L.S. Sherman, H. Morrison, F. Banine, J. Struve, G. Lepperdinger, T. Tuohy and C. Kuntz. Univ. of Cincinnati Col. of Med., Cincinnati, OH and Austrian Acad. of Sci., Inst. of Molec. Biol., Salzburg, Austria. 220 B198 Zfhep transcription factor may influence neural cell differentiation. D.S. Darling, G. Yen, R.T. Zoeller and R.P. Stearman. Univ. of Louisville, Louisville, KY and Univ. of Massachusetts, Amherst, MA. 221 B199 Cloning and expression of CRIM1 and its potential function in the development of the central nervous system. G.V. Kolle, A. Jansen, L. Wilkinson, M.H. Little and T. Yamada. Univ. of Queensland, St. Lucia, Australia. 222 B200 Bone morphogenetic protein control of Wnt ligands, secreted inhibitors and receptors during neural development. C.R. Chesnutt, A.M.C. Brown and L.A. Niswander. Cornell Univ. and Sloan Kettering Inst., New York, NY. 223 B201 BMP signaling in the mammalian dorsal neural tube. R.W. Stottmann, J. Wiedman, Y. Mishina and J.A. Klingensmith. Duke Univ. Med. Ctr., Durham, NC and NIEHS, Res. Triangle Park, NC. 224 PLEASE SEE WORKSHOP 4 Left-Right Asymmetry 225 B203 The zebrafish belladonna mutation specifically affects axon guidance in the ventral forebrain. J. Culverwell, M. Walkowicz and R. Karlstrom. Univ. of Massachusetts, Amherst, MA,. 226 B204 Retinoic acid synthesis for the developing telencephalon. U.C. Drager, D. Smith, E. Wagner, O. Koul and P. McCaffery. Harvard Med. Sch. and U. Mass. Med. Sch., Waltham MA. 227 B205 Isolation of a novel paired-like homeobox gene expressed in the midbrain of mouse embryos. A. Ohtoshi and R.R. Behringer. Univ. of Texas M.D. Anderson Cancer Ctr., Houston, TX. 228 B206 A novel function for EphB2 and EphB3 in maintaining cell shape in the developing ventral midbrain. A. Altick, G. Andrews, C. Cowan, N. Yokoyama, M. Henkemeyer, E. Nilsson and G. Mastick. Univ. of Nevada, Reno, NV. 229 B207 Relevance of TGF-β for the development of ventral midbrain dopaminergic neurons. U. Rauch, L. Farkas and K. Krieglstein. Univ. of Saarland, Homburg/Saar,, Germany. 230 B208 Shh and the isthmus regulate the development of early neurons in the midbrain. N. Fedtsova and E.E. Turner. UCSD, La Jolla, CA and VA Med. Ctr., San Diego, CA. 231 B209 Lmx1b functions in the zebrafish isthmic organizer. R.D. Riddle, P. O'Hara and A. Sebastian. Univ. of Pennsylvania Sch. of Med. Philadelphia, PA. 232 B210 Formation of the mesencephalic/metencephalic boundary. M. Zervas, S. Millet and A. Joyner. Skirball Inst. NYU Med. Ctr., New York, NY. 233 B211 Withdrawn 234 B212 Type I BMP receptors are expressed in cerebellar granular neurons and constitutive activation of the IA receptor induces cerebellar abnormalities. J.E. Ming, M. Elkan, K. Tang and J.A. Golden. Children's Hosp. of Philadelphia and Univ. of Pennsylvania Sch. of Med., Philadelphia, PA. 235 B213 Hedgehog signaling is required for zebrafish motoneuron development. K.E. Lewis and J.S. Eisen. Univ. of Oregon, Eugene OR. 236 B214 Function of zebrafish gli1 and gli2 in motor neuron development. A. Chandrasekhar. Univ. of Missouri, Columbia, MO. 237 B215 Hoxb1 coordinates specification of ventral motoneurons and dorsal interneurons at a specific anteroposterior level. G.O. Gaufo and M.R. Capecchi. Univ. of Utah, Salt Lake City, UT. 238 B216 Ectopic expression of Olig1 is deleterious to V3 interneuron development in the developing CNS. T. Sun, R. Lu, C. Stiles, Y. Echelard and D. Rowitch. Dana-Farber Cancer Inst. and Harvard Med. Sch., Boston, MA. 239 B217 GATA3 identifies a distinct ventral interneuron subtype in the developing spinal cord. A. Karunaratne, M. Hargrave and T. Yamada. Univ. of Queensland, Brisbane, Australia. 240 B218 Regulation and role of neural bHLH factors in spinal cord development. K. Gowan, A.W. Helms, P. Ebert, T. Hunsaker, T. Collisson, R. Odom and J.E. Johnson. Univ. of Texas Southwestern Med. Ctr., Dallas, TX. 241 B219 Hoxa5-overexpressing mice have spinal cord defects that impair sensory performance. K.E. Krieger, I.M. Sonea, M. Abbott and C.K. Tuggle. Iowa State Univ., Ames, IA. 242 B220 Sonic hedgehog signaling is required for proper development of zebrafish dorsal root ganglia. J.M. Ungos and D.W. Raible. Univ. of Washington, Seattle, WA. 243 B221 A genetic screen to identify zebrafish enteric nervous system mutants. I. Shepherd, T. Linbo and D. Raible. Univ. of Washington, Seattle, WA. 244 B222 Expression of chick calcium channel gamma subunit in differentiating neurons and myoblasts. A. Knecht, B. Kious and M. Bronner-Fraser. Caltech, Pasadena, CA. 245 B223 Neuronal cell differentiation in the developing mouse brain is influenced by peripheral axonal inputs from sensory and motor neurons. B. Kablar and M.A. Rudnicki. Dalhousie Univ., Halifax, Canada and Ottawa Hosp. Res. Inst., Ottawa, Canada. 246 B224 Multiple levels of auto-regulation on FGF signaling during mouse mid/hindbrain early patterning. A. Liu and A.L. Joyner. Skirball Inst., New York Univ. Sch. of Med., New York, NY. 247 B225 FGF signaling mediates an organizing activity in the zebrafish hindbrain. L. Maves and C.B. Kimmel. Univ. of Oregon, Eugene, OR. 248 B226 Role of nlz, a novel zinc finger protein, in the development of the zebrafish hindbrain. A.P. Runko and C.G. Sagerstrom. Univ. of Massachusetts Med. Ctr., Worcester, MA. 249 B227 Mosaic analysis of antennal lobe projection neurons suggests olfactory system connectivity is genetically predetermined. E.C. Marin, G.S.X.E. Jefferis, R.F. Stocker and L. Luo. Stanford Univ., Stanford, CA and Univ. of Fribourg, Perolles, Switzerland. 250 B228 Development of the avian olfactory placode. S. Bhattacharyya and M. Bronner-Fraser. California Inst. of Technol., Pasadena, CA. 251 B229 TGF-β modulates programmed cell death in the developing chick retina. N. Duenker, N. Schuster and K. Krieglstein. Univ. of Saarland, Homburg/Saar, Germany. 252 B230 The multipotency of retinal progenitor cells depends on Pax6 function. T. Marquardt, R. Ashery-Padan, N. Andrejewski and P. Gruss. Max-Planck Inst. of Biophys. Chem., Goettingen, Germany. 253 B231 Changes in the sensitivity to apoptosis during development of the retina are associated with Ref-1 expression. L.B. Chiarini, M.L. Leal-Ferreira, F.G. Freitas and R. Linden. UFRJ, Rio de Janeiro, Brazil. 254 B232 Characterization of retinal differentiation in zebrafish lacking the sonic hedgehog gene. D.M. Mallory, R.A. Frey and D.L. Stenkamp. Univ. of Idaho, Moscow, ID. 255 B233 Withdrawn 256 B234 IL-1β induces FGF production in the embryonic chick retina. E.I. Barragan, S.A. Avila, V. Chafrat and J. Cerdeira. Univ. Nacional del Comahue. Toschi and Arrayanes. Cipolletti Rio Negro, Argentina. 257 B235 Localization of components of the retinoic acid (RA) signaling system and effects of RA on photoreceptor patterning in embryonic zebrafish retina. S.N. Prabhudesai and D.L. Stenkamp. Univ. of Idaho, Moscow, ID. 258 B236 Taurine and the glycine receptor in vertebrate retinal development. T.L. Young and C.L. Cepko. Harvard Med. Sch., Boston, MA. 259 B237 Ath5 is required for retinal ganglion cell and optic nerve formation. N.L. Brown, S. Patel, J. Brzezinski and T. Glaser. Univ. of Michigan, Ann Arbor, MI and Northwestern Univ. Med. Sch, Chicago, IL 260 B238 Genetic analysis of neural stem cells in zebrafish retina. A. Wehman and H. Baier. Univ. of California, San Francisco, CA. |
| 3:30-3:45pm | Break |
| 4-5:30pm | Workshops |
| 1. Stem Cells | HUB Ballroom |
| Chair: | Janet Rossant |
| 261 | 4:00 | Janet Rossant
(Samuel Lunenfeld Research Institute, Canada) Stem cells from the mouse blastocyst |
| 262 | 4:20 | James Sherley
(Massachusetts Institute of Technology) Molecular determinants of asymmetric stem cell kinetics |
| 263 | 4:40 | Melissa
Carpenter (Geron Corporation) Lineage specific differentiation of human embryonic stem cells |
| 5:00 | Discussion |
| 2. Imaging and Cell Marking | Kane 120 |
| Chair: | Andras Nagy |
| 4:00 | Andras Nagy (Samuel Lunenfeld Research Institute, Canada) |
| 264 | 4:20 | Mary
Dickinson (Caltech) Analysis of somite development using a multi-photon, multispectral approach |
| 265 | 4:40 | Steven A. Farber
(Thomas Jefferson University) Visualizing lipid metabolism in live zebrafish |
| 5:00 | Discussion |
| 5:30-7pm | Dinner | McMahon |
| 7-9pm | Plenary
Session I Organ Building |
HUB Ballroom |
| Chair: | Cliff Tabin |
| 7:00 | Cliff
Tabin (Harvard Medical School) Patterning the chick embryo |
| 266 | 7:30 | Bruce
Morgan (Massachusetts General Hospital) Inductive signals that initiate feather bud development |
| 267 | 8:00 | Charles
Gasser (UC Davis) Genetic analysis of ovule morphogenesis |
| 268 |